scholarly journals Chemical Composition, Antioxidant, Antimicrobial, and α-Glucosidase Activities of Essential Oils of Hornstedtia scyphifera (Zingiberaceae)

2018 ◽  
Vol 13 (2) ◽  
pp. 1934578X1801300 ◽  
Author(s):  
Siti Ernieyanti Hashim ◽  
Hasnah Mohd Sirat
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Moderate Activity ◽  
Gram Positive Bacteria ◽  
Germacrene D ◽  
Leaf Oil ◽  
Inhibition Zones ◽  
First Time ◽  
Dpph Radical Scavenging ◽  
Β Carotene

The essential oil compositions of the rhizomes, flowers, leaves, and pseudostems of Hornstedtia scyphifera (J. Koenig) Steud were studied for the first time. A total of forty three constituents were identified from the rhizome, flower, leaf, and pseudostem oils, representing 90.9%, 82.4%, 79.7%, and 82.6%, respectively. α-Selinene was found dominant in the flower (10.8%) and pseudostem (12.4%) oils, while the rhizome and leaf oils contained germacrene D (15.5%) and camphor (12.6%) as the main constituents, respectively. The rhizome, flower, and leaf oils showed moderate activity against Gram positive bacteria with MIC values of 225 to 450 μg/mL and inhibition zones of 8.4 to 10.0 mm. The leaf oil showed good β-carotene bleaching inhibition activity (64.8%) and a low IC50 value for DPPH radical scavenging activity (650.4 μg/mL). The flower oil showed potential α-glucosidase inhibitory activity with an IC50 value of 21.44 μg/mL.

STUDY OF ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF SAXICOLOUS LICHEN $ \textit{XANTHOPARMELIA STENOPHYLLA} $

2020 ◽  
Vol 54 (2 (252)) ◽  
pp. 132-137
Author(s):  
A.G. Simonyan ◽  
R.R. Sargsyan ◽  
H.H. Panosyan ◽  
A.H. Trchounian
Keyword(s):  
Methanol Extract ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Dpph Radical ◽  
Dpph Radical Scavenging Activity ◽  
Gram Positive Bacteria ◽  
Acetone Extracts ◽  
Dpph Radical Scavenging

Antibacterial and antioxidant activities of different extracts of saxicolous lichen Xanthoparmelia stenophylla sampled from Norashen, Gegharkunik Province of Armenia were studied. Methanol, ethanol and acetone extracts of lichen thalli were demonstrated to have activity against only tested gram-positive bacteria. Methanol extract of the lichen showed the highest amount of DPPH radical scavenging activity (~68%). Our studies did not reveal any significant antibacterial and antioxidant activities of aqueous extract.

scholarly journals Investigation of the bioactivities of extracts from Vernonia Amygdalina Del

2021 ◽  
Vol 947 (1) ◽  
pp. 012040
Author(s):  
Nga Phan Thi Thanh ◽  
Thanh Truc Tran
Keyword(s):  
Survival Rate ◽  
Cancer Cells ◽  
Inhibitory Concentration ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanol Extract ◽  
Dpph Assay ◽  
Vernonia Amygdalina ◽  
Gram Positive Bacteria ◽  
Dpph Radical Scavenging

Abstract The antibacterial, antioxidant activity, and anticancer of the extract from Vernonia Amygdalina Del leaves, was assessed towards 6 selected bacteria, in the DPPH test, as well as on hepatic (HepG2), blood (K562) cancer cell lines. The DPPH assay revealed that the highest DPPH radical scavenging activity with the warm ethanol extract (IC50 = 259,03 ± 5,42 μg/mL). And the ethyl acetate extract showed a high antibacterial effect expressed as minimum inhibitory concentration (MIC = 100 mg/mL) against Gram-positive bacteria. At the concentration of 250 mg/mL, this extract also demonstrated its ability to resist blood cancer cells K562 (with a survival rate of 25%) and liver cancer cells HepG2 (with a survival rate of 0%).

scholarly journals Chemical Composition, Antioxidant, and Antimicrobial Activities of Essential Oils of Endlicheria arenosa (Lauraceae) from the Amazon

2016 ◽  
Vol 11 (5) ◽  
pp. 1934578X1601100 ◽  
Author(s):  
Joyce Kelly R. da Silva ◽  
Rafaela C. S. da Trindade ◽  
José Guilherme S. Maia ◽  
William N. Setzer
Keyword(s):  
Chemical Composition ◽  
Essential Oils ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Antimicrobial Activities ◽  
Dpph Radical ◽  
Volatile Oils ◽  
Sesquiterpene Hydrocarbons ◽  
Germacrene D ◽  
Dpph Radical Scavenging

The essential oils (EOs) of leaves and twigs of Endlicheria arenosa Chanderb. were obtained by hydrodistillation using a Clevenger-type apparatus and the chemical composition was determined by GC and GC-MS. In total, 47 constituents were identified and sesquiterpene hydrocarbons (77.6%) were the main compounds found in the leaf EO, such as bicyclogermacrene (42.2%), germacrene D (12.5%) and β-caryophyllene (10.1%). Limonene (33.2%), terpinen-4-ol (15.6%) and δ-cadinol (6.9%) were the predominant constituents in the EO of the twigs. Using the DPPH radical-scavenging method, the EO of the leaves showed the greater radical-scavenging activity (216.5 ± 11.6 mg Trolox equivalents (TE)/mL compared to the EO of the twigs (122.6 ± 6.8 mg TE/mL). Also, the EO of leaves displayed promising antimicrobial activity against Escherichia coli (MIC 19.5 μg•mL−1). The present study is the first report about evaluation of volatile oils for this species.

scholarly journals β-ecdysone content and antioxidant capacity in different organs of Brazilian ginseng

2021 ◽  
Vol 51 (5) ◽  
Author(s):  
Lucas Dutra Zani da Silva Souza ◽  
Stéphane Raquel Almeida Velande da Fonseca ◽  
Ariana Ferrari ◽  
Daniele Fernanda Felipe
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Capacity ◽  
High Performance ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Antioxidant Compounds ◽  
Dpph Radical ◽  
Brazilian Ginseng ◽  
Dpph Radical Scavenging ◽  
Β Carotene

ABSTRACT: Plants that contain antioxidant compounds have attracted increasing interest for their vital role in the attenuation of oxidative damage caused by free radicals and in the treatment of various diseases. The present study investigated the β-ecdysone content and the antioxidant activity of Brazilian ginseng (Pfaffia glomerata) extracts obtained from inflorescences, stems, and roots. The P. glomerata extracts were tested for antioxidant activity using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method, β-carotene bleaching test, and phosphomolybdenum method. The β-ecdysone content of P. glomerata extracts was measured by high-performance liquid chromatography (HPLC). The P. glomerata inflorescences showed the strongest DPPH radical scavenging activity and the strongest antioxidant activity in the β-carotene bleaching assay and phosphomolybdenum test. The roots showed the lowest antioxidant capacity in all of the assays. The concentration of β-ecdysone in the plant organs followed the following decreasing order: inflorescences > stems > roots. The present study showed that P. glomerata inflorescence extract had high antioxidant capacity that could be attributed to the presence of β-ecdysone.

scholarly journals Radical Scavenging, Proteases Activities, and Phenolics Composition of Bark Extracts from 21 Medicinal Plants

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Muhammad Asam Raza ◽  
Durre Shahwar ◽  
Tania Khan
Keyword(s):  
Medicinal Plants ◽  
Room Temperature ◽  
Antiradical Activity ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Total Phenolic ◽  
Moderate Activity ◽  
Phenolic Contents ◽  
Acetone Water ◽  
First Time

Stem barks derived from twenty-one medicinal plants were extracted in methanol (100%) and acetone-water (70 : 30 v/v) and at room as well as at reflux temperature conditions. Total phenolic contents, determined using FC (Folin Ciocalteu) reagent, ranged from 528 to 715 mg GAE/g of crude extract. 15 out of 21 plants showed DPPH activity more than 90% and the rest of plants exhibited the activity in the range of 87–89%. The methanolic extract ofP. granatumobtained at room temperature showed the highest antiradical activity (96%). The extracts with similar % radical scavenging of DPPH∙showed significant variation in EC50value. Radical scavenging activity ofE. rostrata, M. champaca, A. modesta, P. roxburghii, P. longifolia, E. suberosa,andF. infectoriawas evaluated for the first time. A strong correlation between total phenols and antiradical activity was exhibited withRvalues ranging from 0.7580 to 0.8874 indicating a linear relationship The extracts phenolic composition was studied by HPLC. All extracts showed remarkable antioxidant activity (87 to 96%) while moderate activity was exhibited against protease (22 to 56%). Gallic acid, tannic acid, quercetin, rutin, catechin, hesperidin, and cinnamic acid were identified as the major phenolic acids in the extracts of selected medicinal plants.

scholarly journals DMFDMA catalyzed synthesis of 2-((Dimethylamino)methylene)-3,4-dihydro-9-arylacridin-1(2H)-ones and their derivatives: in-vitro antifungal, antibacterial and antioxidant evaluations

2018 ◽  
Vol 16 (1) ◽  
pp. 1077-1088
Author(s):  
L. Jyothish Kumar ◽  
S. Sarveswari ◽  
V. Vijayakumar
Keyword(s):  
Antibacterial Activity ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Gram Negative Bacteria ◽  
Dpph Radical ◽  
Dpph Radical Scavenging Activity ◽  
Gram Positive Bacteria ◽  
Dpph Radical Scavenging ◽  
Mic Value

AbstractA series of 3,4-dihydro-9-arylacridin-1(2H)-ones was synthesized and enaminone function was introduced at the C-2 position using DMFDMA catalyst which in turn successfully converted into pyrazole, isoxazol, 1-phenyl-1H-pyrazole by treating it with reagents such as hydrazine, hydroxylamine and phenylhydrazine. These newly synthesized compounds were evaluated for their antibacterial activity against a series of Gram-Positive bacteria including Staphylococcusaureus, Bacilluscereus, StaphylococcusaureusMLS16 and Gram-Negative bacteria including Klebsiellaplanticol, Escherichiacoliand Pseudomonasaeruginosaand also against fungal strains including Candidaalbicans, Candidaparapsilosis, Candidaglabrata, Candidaaaseri, Aspergillusnigerand Issatchenkiahanoiensis. The compounds3aand6aexhibited considerable antifungal activity (MIC value 0.007 and 0.006 μM) against Candidaalbicansand Aspergillusnigerrespectively. The compound4ashowed excellent antibacterial activity towards EscherichiaColi(MIC = 0.003 μM) and the compound5afound to show prominent DPPH radical scavenging activity with EC50value 16.85±1.5μg mL−1.

scholarly journals Hydrolysable Tannins and Biological Activities of Meriania hernandoi and Meriania nobilis (Melastomataceae)

Molecules ◽  
2019 ◽  
Vol 24 (4) ◽  
pp. 746
Author(s):  
Claudia Valverde Malaver ◽  
Ana Colmenares Dulcey ◽  
Carlos Rial ◽  
Rosa Varela ◽  
José Molinillo ◽  
...  
Keyword(s):  
Biological Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Wheat Coleoptile ◽  
Leaf Extracts ◽  
Antioxidant Power ◽  
Hydrolysable Tannins ◽  
Nmr Techniques ◽  
First Time ◽  
Dpph Radical Scavenging

A bio-guided study of leaf extracts allowed the isolation of two new macrobicyclic hydrolysable tannins, namely merianin A (1) and merianin B (2), and oct-1-en-3-yl β-xylopyranosyl-(1”-6’)-β-glucopyranoside (3) from Meriania hernandoi, in addition to 11 known compounds reported for the first time in the Meriania genus. The structures were elucidated by spectroscopic analyses including one- and two-dimensional NMR techniques and mass spectrometry. The bioactivities of the compounds were determined by measuring the DPPH radical scavenging activity and by carrying out antioxidant power assays (FRAP), etiolated wheat coleoptile assays and phytotoxicity assays on the standard target species Lycopersicum esculentum W. (tomato). Compounds 1 and 2 exhibited the best free radical scavenging activities, with FRS50 values of 2.0 and 1.9 µM, respectively.

scholarly journals Polyketides and Meroterpenes from the Marine-Derived Fungi Aspergillus unguis 158SC-067 and A. flocculosus 01NT-1.1.5 and Their Cytotoxic and Antioxidant Activities

Marine Drugs ◽  
2021 ◽  
Vol 19 (8) ◽  
pp. 415
Author(s):  
Cao Van Anh ◽  
Jong Soon Kang ◽  
Byeoung-Kyu Choi ◽  
Hwa-Sun Lee ◽  
Chang-Su Heo ◽  
...  
Keyword(s):  
Cell Lines ◽  
Spectroscopic Data ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Dpph Radical ◽  
Dpph Radical Scavenging Activity ◽  
Aspergillus Unguis ◽  
First Time ◽  
Dpph Radical Scavenging

Ten secondary metabolites, including a new grifolin analog, grifolin B (1); a new homovalencic acid derivative, 12-hydroxyhomovalencic acid (7); and a compound isolated from a natural source for the first time (9), along with seven known compounds, grifolin (2), averantin (3), 7-chloroaverantin (4), 1′-O-methylaverantin (5), 7-hydroxy-2-(2-hydroxypropyl)-5-pentylchromone (6), homovalencic acid (8), and bekeleylactone E (10), were isolated from two fungal strains. The structures of 1–10 were identified by detailed analysis and comparison of their spectroscopic data with literature values. Compounds 9 and 10 showed moderate cytotoxic activity against a panel of cancer cell lines (PC-3, HCT-15, MDA-MB-231, ACHN, NCI-H23, NUGC-3), with the GI50 values ranging from 1.1 µM to 3.6 µM, whereas 1 displayed a weak 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity without cytotoxicity against all tested cell lines.

scholarly journals Bioactive Constituents from the Traditional Kurdish plant Iris persica

2018 ◽  
Vol 13 (9) ◽  
pp. 1934578X1801300 ◽  
Author(s):  
Hawraz Ibrahim M. Amin ◽  
Faiq H. S. Hussain ◽  
Marcello Maggiolini ◽  
Giovanni Vidari
Keyword(s):  
Biological Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Human Tumor ◽  
Bioactive Constituents ◽  
Human Tumor Cells ◽  
Dpph Radical Scavenging Activity ◽  
Phytochemical Investigation ◽  
First Time ◽  
Dpph Radical Scavenging

In the first phytochemical investigation of non-volatile secondary metabolites from the Kurdish traditional plant Iris persica L, (-)-embinin was isolated from flowers and leaves, isovitexin from flowers, trans-resveratrol-3- O-β-D-glucopyranoside from rhizomes and tectorigenin from bulbs. The complete NMR spectra of embinin are reported for the first time. In an MTT assay, embinin showed an inhibition activity higher than the well-known antitumor drug cisplatin against five of the six tested human tumor cells. Moreover, embinin showed a significant DPPH radical scavenging activity (IC50 value of 112.16) comparable to the reference antioxidant ascorbic acid. The remarkable biological activities exhibited by the extracts of Iris persica and isolated compounds have validated the uses of I. persica in the traditional medicine of Kurdistan.

Carum copticum L. essential oils as natural antimicrobial and antioxidant

2018 ◽  
Vol 44 (4) ◽  
pp. 515-520
Author(s):  
M Kazemi
Keyword(s):  
Essential Oils ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Dpph Radical ◽  
Dpph Radical Scavenging Activity ◽  
Carum Copticum ◽  
Microbial Strains ◽  
Pharmaceutical Industries ◽  
Dpph Radical Scavenging ◽  
Antioxidant Effects

Carum copticum L. comprises several relevant species for food, cosmetic, perfumery and pharmaceutical industries. GC/MS analysis of the enential oil of C. copticum revealed γ- terpinene as a major component of C. copticum, with its contribution of 33.85%. Essential oils (EOs) exhibited a significant antimicrobial activity against all tested microbial strains. In addition, the C. copticum oil demonstrated the highest DPPH radical scavenging activity. These results clearly show the antimicrobial and antioxidant effects of the plant essential oil.

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