Predictive factors of short‐term mortality in ischaemic colitis and development of a new prognostic scoring model of in‐hospital mortality

Introduction: Anemia is a common condition encountered in acute ischemic stroke, and only a few pieces of evidence has been produced suggesting its possible association with short-term mortality have been produced. The study sought to assess whether admission anemia status had any impact on short-term clinical outcome among oldest-old patients with acute ischemic stroke. Materials and Methods: A retrospective review of Electronic Medical Recording System was performed in 2 tertiary hospitals. Data, from the oldest-old patients aged > = 80 years consecutively admitted with a diagnosis of acute ischemic stroke between January 1, 2015, and December 31, 2019, were analyzed. Admission hemoglobin was used as indicator for anemia and severity. Univariate and multivariate regression analyses were used to compare in-hospital mortality and length of in-hospital stay in different anemia statuses and normal hemoglobin patients. Results: A total of 705 acute ischemic stroke patients were admitted, and 572 were included in the final analysis. Of included patients, 240 of them were anemic and 332 nonanemic patients. A statistical difference between the 2 groups was found in in-hospital mortality (p < 0.001). After adjustment for baseline characteristics, the odds ratio value of anemia for mortality were 3.91 (95% confidence intervals (CI) 1.60–9.61, p = 0.003) and 7.15 (95% CI: 1.46–34.90, p = 0.015) in moderate and severely anemic patients, respectively. Similarly, length of in-hospital stay was longer in anemic patients (21.64 ± 6.17 days) than in nonanemic patients (19.08 ± 5.48 days, p < 0.001). Conclusions: Increased severity of anemia may be an independent risk factor for increased in-hospital mortality and longer length of stay in oldest-old patients with acute ischemic stroke.

Download Full-text

Low Body Mass Index and Low Serum Albumin Are Predictive Factors for Short-Term Mortality in Elderly Japanese Requiring Home Care

The Tohoku Journal of Experimental Medicine ◽

10.1620/tjem.221.29 ◽

2010 ◽

Vol 221 (1) ◽

pp. 29-34 ◽

Cited By ~ 25

Author(s):

Kaori Kitamura ◽

Kazutoshi Nakamura ◽

Tomoko Nishiwaki ◽

Kimiko Ueno ◽

Mariko Hasegawa

Keyword(s):

Body Mass Index ◽

Home Care ◽

Serum Albumin ◽

Body Mass ◽

Predictive Factors ◽

Short Term ◽

Short Term Mortality ◽

Low Body Mass Index ◽

Elderly Japanese ◽

Low Serum

Download Full-text

qSOFA is a Poor Predictor of Short-Term Mortality in All Patients: A Systematic Review of 410,000 Patients

Journal of Clinical Medicine ◽

10.3390/jcm8010061 ◽

2019 ◽

Vol 8 (1) ◽

pp. 61 ◽

Cited By ~ 14

Author(s):

Ronson S. L. Lo ◽

Ling Yan Leung ◽

Mikkel Brabrand ◽

Chun Yu Yeung ◽

Suet Yi Chan ◽

...

Keyword(s):

Hospital Mortality ◽

Case Reports ◽

Meta Analysis ◽

Case Series ◽

Short Term ◽

Predictive Values ◽

Icu Length Of Stay ◽

Ovid Medline ◽

Failure Assessment ◽

Short Term Mortality

Background: To determine the validity of the Quick Sepsis-Related Organ Failure Assessment (qSOFA) in the prediction of outcome (in-hospital and 1-month mortality, intensive care unit (ICU) admission, and hospital and ICU length of stay) in adult patients with or without suspected infections where qSOFA was calculated and reported; Methods: Cochrane Central of Controlled trials, EMBASE, BIOSIS, OVID MEDLINE, OVID Nursing Database, and the Joanna Briggs Institute EBP Database were the main databases searched. All studies published until 12 April 2018 were considered. All studies except case series, case reports, and conference abstracts were considered. Studies that included patients with neutropenic fever exclusively were excluded. Results: The median AUROC for in-hospital mortality (27 studies with 380,920 patients) was 0.68 (a range of 0.55 to 0.82). A meta-analysis of 377,623 subjects showed a polled AUROC of 0.68 (0.65 to 0.71); however, it also confirmed high heterogeneity among studies (I2 = 98.8%, 95%CI 98.6 to 99.0). The median sensitivity and specificity for in-hospital mortality (24 studies with 118,051 patients) was 0.52 (range 0.16 to 0.98) and 0.81 (0.19 to 0.97), respectively. Median positive and negative predictive values were 0.2 (range 0.07 to 0.38) and 0.94 (0.85 to 0.99), respectively.

Download Full-text

The impact of right ventricular injury on the mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis

Critical Care ◽

10.1186/s13054-021-03591-9 ◽

2021 ◽

Vol 25 (1) ◽

Author(s):

Ryota Sato ◽

Siddharth Dugar ◽

Wisit Cheungpasitporn ◽

Mary Schleicher ◽

Patrick Collier ◽

...

Keyword(s):

Systematic Review ◽

Acute Respiratory Distress Syndrome ◽

Hospital Mortality ◽

Respiratory Distress Syndrome ◽

Distress Syndrome ◽

Meta Analysis ◽

Icu Mortality ◽

Short Term ◽

Short Term Mortality ◽

The Impact

Abstract Background Previous studies have found various incidences of right ventricular (RV) injury and its association with clinical outcome in patients with acute respiratory distress syndrome (ARDS). In this systematic review and meta-analysis, we aimed to investigate the impact of the presence of RV injury on mortality in patients with ARDS. Method We searched Medline, Embase, and the Cochrane Central Register of Controlled Trials for studies investigating the association between RV injury and mortality. Two authors independently evaluated whether studies meet eligibility criteria and extracted the selected patients’ and studies’ characteristics and outcomes. RV injury was diagnosed by trans-thoracic echocardiogram (TTE), trans-esophageal echocardiogram (TEE) and PAC (pulmonary artery catheter) in the included studies. The primary outcome was the association between mortality and the presence of RV injury in patients with ARDS. The overall reported mortality was defined as either the intensive care unit (ICU) mortality, in-hospital mortality, or mortality within 90 days, and short-term mortality was defined as ICU-mortality, in-hospital mortality, or mortality within 30 days. Results We included 9 studies (N = 1861 patients) in this meta-analysis. RV injury that included RV dysfunction, RV dysfunction with hemodynamic compromise, RV failure, or acute cor-pulmonale was present in 21.0% (391/1,861). In the pooled meta-analysis, the presence of RV injury in patients with ARDS was associated with significantly higher overall mortality (OR 1.45, 95% CI 1.13–1.86, p-value = 0.003, I2 = 0%), as well as short-term mortality (OR 1.48, 95% CI 1.14–1.93, p-value = 0.003, I2 = 0%). Conclusion In this systematic review and meta-analysis including 1861 patients with ARDS, the presence of RV injury was significantly associated with increased overall and short-term mortality. Trial registration: The protocol was registered at PROSPERO (CRD42020206521).

Download Full-text

Prognostic value of HbA1c for in-hospital and short-term mortality in patients with acute coronary syndrome: a systematic review and meta-analysis

Cardiovascular Diabetology ◽

10.1186/s12933-019-0970-6 ◽

2019 ◽

Vol 18 (1) ◽

Cited By ~ 5

Author(s):

Wenjun Pan ◽

Haining Lu ◽

Baotao Lian ◽

Pengda Liao ◽

Liheng Guo ◽

...

Keyword(s):

Systematic Review ◽

Acute Coronary Syndrome ◽

Hospital Mortality ◽

Meta Analysis ◽

Hospital Death ◽

Short Term ◽

Coronary Syndrome ◽

Relative Risks ◽

Short Term Mortality ◽

The Relationship

Abstract Background HbA1c, the most commonly used indicator of chronic glucose metabolism, is closely associated with cardiovascular disease. However, the relationship between HbA1c and the mortality of acute coronary syndrome (ACS) patients has not been elucidated yet. Here, we aim to conduct a systematic review assessing the effect of HbA1c on in-hospital and short-term mortality in ACS patients. Methods Relevant studies reported before July 2019 were retrieved from databases including PubMed, Embase, and Central. Pooled relative risks (RRs) and the corresponding 95% confidence interval (CI) were calculated to evaluate the predictive value of HbA1c for the in-hospital mortality and short-term mortality. Results Data from 25 studies involving 304,253 ACS patients was included in systematic review. The pooled RR of in-hospital mortality was 1.246 (95% CI 1.113–1.396, p: 0.000, I2 = 48.6%, n = 14) after sensitivity analysis in studies reporting HbA1c as categorial valuable. The pooled RR was 1.042 (95% CI 0.904–1.202, p: 0.57, I2 = 82.7%, n = 4) in random-effects model for studies reporting it as continuous valuable. Subgroup analysis by diabetic status showed that elevated HbA1c is associated increased short-term mortality in ACS patients without diabetes mellitus (DM) history and without DM (RR: 2.31, 95% CI (1.81–2.94), p = 0.000, I2 = 0.0%, n = 5; RR: 2.56, 95% CI 1.38–4.74, p = 0.003, I2 = 0.0%, n = 2, respectively), which was not the case for patients with DM and patients from studies incorporating DM and non-DM individuals (RR: 1.16, 95% CI 0.79–1.69, p = 0.451, I2 = 31.9%, n = 3; RR: 1.10, 95% CI 0.51–2.38), p = 0.809, I2 = 47.4%, n = 4, respectively). Conclusions Higher HbA1c is a potential indicator for in-hospital death in ACS patients as well as a predictor for short-term mortality in ACS patients without known DM and without DM.

Download Full-text

U-Shaped Association Between Serum Uric Acid and Short-Term Mortality in Patients With Infective Endocarditis

Frontiers in Endocrinology ◽

10.3389/fendo.2021.750818 ◽

2021 ◽

Vol 12 ◽

Author(s):

Xuebiao Wei ◽

Bingqi Fu ◽

Xiaolan Chen ◽

WeiTao Chen ◽

Zhenqian Wang ◽

...

Keyword(s):

Uric Acid ◽

Infective Endocarditis ◽

Hospital Mortality ◽

Hospital Death ◽

Short Term ◽

Current Definition ◽

Short Term Mortality ◽

Previous Definition ◽

Independent Risk Factors ◽

Definition Of

BackgroundIncreased uric acid (UA) levels have been reported to be associated with poor clinical outcomes in several conditions. However, the prognostic value of UA in patients with infective endocarditis (IE) is yet unknown.MethodsA total of 1,117 patients with IE were included and divided into two groups according to the current definition of hyperuricemia (UA>420 μmol/L in men and >360 μmol/L in women): hyperuricemia group (n=336) and normouricemia group (n=781). The association between the UA level and short-term outcomes were examined.ResultsThe in-hospital mortality was 6.2% (69/1117). Patients with hyperuricemia carried a higher risk of in-hospital death (9.8% vs. 4.6%, p=0.001). Hyperuricemia was not an independent risk factor for in-hospital death (adjusted odds ratio [aOR]=1.92, 95% confidence interval [CI]: 0.92-4.02, p=0.084). A U-shaped relationship was found between the UA level and in-hospital death (p<0.001). The in-hospital mortality was lower in patients with UA in the range 250–400 μmol/L. The aOR of in-hospital death in patients with UA>400 and <250 μmol/L was 3.48 (95% CI: 1.38-8.80, p=0.008) and 3.28 (95%CI: 1.27-8.51, p=0.015), respectively. Furthermore, UA>400 μmol/L (adjusted hazard ratio [aHR]=3.54, 95%CI: 1.77-7.07, p<0.001) and <250 μmol/L (aHR=2.23, 95%CI: 1.03-4.80, p=0.041) were independent risk factors for the 6-month mortality.ConclusionThe previous definition of hyperuricemia was not suitable for risk assessment in patients with IE because of the U-shaped relationship between UA levels and in-hospital death. Low and high levels of UA were predictive of increased short-term mortality in IE patients.

Download Full-text

Predictive factors of short-term mortality after PEG placement

The American Journal of Gastroenterology ◽

10.1016/s0002-9270(01)03647-4 ◽

2001 ◽

Vol 96 (9) ◽

pp. S272

Author(s):

N KIYICI

Keyword(s):

Predictive Factors ◽

Short Term ◽

Short Term Mortality

Download Full-text

SOFA score and short-term mortality in acute decompensated heart failure

Scientific Reports ◽

10.1038/s41598-020-77967-2 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Adi Elias ◽

Reham Agbarieh ◽

Walid Saliba ◽

Johad Khoury ◽

Fadel Bahouth ◽

...

Keyword(s):

Heart Failure ◽

High Risk ◽

Hospital Mortality ◽

Sofa Score ◽

Acute Decompensated Heart Failure ◽

Decompensated Heart Failure ◽

Short Term ◽

High Risk Patients ◽

Short Term Mortality ◽

Risk Patients

AbstractAcute decompensated heart failure (ADHF) is one of the leading causes for hospitalization and mortality. Identifying high risk patients is essential to ensure proper management. Sequential Organ Function Assessment Score (SOFA) is considered an excellent score to predict short-term mortality in sepsis and other life-threatening conditions. To assess the capability of SOFA score in predicting short-term mortality in ADHF. We retrospectively identified patients with first hospitalization with primary diagnosis of ADHF between the years (2008–2018). The SOFA score was calculated for all patients. A total 3232 patients were included in the study. The SOFA score was significantly associated with in-hospital mortality and 30-day mortality. The odds ratios for 1-point increase in the SOFA score were 1.86 (95% CI 1.68–1.96) and 1.627 (95% CI 1.523–1.737) respectively. The SOFA Score demonstrated a good predictive accuracy. The areas under the curve of receiver operating characteristic curves for in-hospital mortality and 30-day mortality were 0.765 (95% CI 0.733–0.798) and 0.706 (95% CI 0.676–0.736) respectively. SOFA score is associated with increased risk of short-term mortality in ADHF. SOFA can be used as a complementary risk score to screen high risk patients who need strict monitoring.

Download Full-text