scholarly journals Blunted Reward Sensitivity and Trait Disinhibition Interact to Predict Substance Use Problems

2019 ◽  
Vol 7 (5) ◽  
pp. 1109-1124 ◽  
Author(s):  
Keanan J. Joyner ◽  
Colin B. Bowyer ◽  
James R. Yancey ◽  
Noah C. Venables ◽  
Jens Foell ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Dependence ◽  
Reward Processing ◽  
Reward Sensitivity ◽  
Future Research ◽  
Cross Sectional ◽  
Reward Positivity ◽  
New Information ◽  
Cross Sectional Design ◽  
And Gender

Reward-deficit models of addiction posit weaknesses in reward sensitivity to be promotive of substance dependence, whereas the externalizing spectrum model views substance problems as arising in large part from a general disinhibitory liability. In the current study we sought to integrate these perspectives by testing for separate and interactive associations of disinhibition and reward dysfunction with interview-assessed substance use disorders (SUDs). Community and college adults ( N = 199) completed a scale measure of trait disinhibition and performed a gambling-feedback task yielding a neural index of reward sensitivity, the “Reward Positivity” (RewP). Disinhibition and blunted RewP independently predicted SUDs and also operated synergistically, such that participants—in particular, men—with high levels of disinhibition together with blunted RewP exhibited especially severe substance problems. Though limited by its cross-sectional design, this work provides new information about the interplay of disinhibition, reward processing, and gender in SUDs and suggests important directions for future research.

FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PERNIKAHAN DINI DI DUSUN I DESA BARU KEC PANCUR BATU DELI SERDANG SUMATERA UTARA TAHUN 2017

2019 ◽  
Vol 4 (1) ◽  
pp. 41-49
Author(s):  
Meriati Bunga Arta Purba
Keyword(s):  
Divorce Rate ◽  
Drop Out ◽  
Early Marriage ◽  
P Value ◽  
Cross Sectional ◽  
Birth Complication ◽  
Sexuality And Gender ◽  
Analytical Research ◽  
Cross Sectional Design ◽  
And Gender

Based on the research by the Sexuality and Gender Study Center of University of Indonesia, the rate of early marriage in Indonesia is the second highest in Southeast Asian in which 2 million out of 7.3 million women below 15 years old are married and drop out from school. Early marriage hinders them from going to school, causes pregnancy and birth complication, impedes the achievement of KB (Family Planning) Program and increases divorce rate. Goals : The objective of the research was to discover the correlation of value of virginity, knowledge and trust with early marriage at Dusun I Desa Baru. Methods: This is an observational analytical research with cross sectional design. It was done at Dusun I Desa Baru, Pancur Batu Subdistrict from November, 2017 until February, 2018. The population covered the teenagers below 20 years old which was all taken as the research samples i.e. 139 people. The dependent variable was early marriage, while the independent variables were parent income, trust, knowledge and value of virginity. The data were collected through questionnaires. Multiple logistic regression testing was employed to analyze the data. Result : The research results demonstrated that the variable with the most dominant influence was parent income at p-value = 0.006 (p<0.05) and Exp. β value = 3.675, followed by the variable of trust at p-value = 0.027 (p<0.05) and Exp. β value = 2.368, the variable of knowledge at p-value = 0.003 (p<0.05) and Exp. β value 6.064, and the variable of virginity at p-value = 0.003 (p<0.05) and Exp. Β value = 6.064. Based on these results, it was concluded that f(y) was 97%. It indicated that the probability of the variables of parent income, trust, knowledge and virginity influenced early marriage of 97.7%. Conclusion: It is recommended that the local government cooperate with local Puskesmas, Religious Figures, and Parents to conduct counseling to improve people’s knowledge of the ideal age to get married, so that they can prevent from possible problems due to early marriage and provide their children parent income at early age the importance of protecting their virginity until they get married.

A test of the interpersonal-psychological theory of suicidal behaviour in a sample of mental health outpatients

2018 ◽  
Vol 49 (3) ◽  
pp. 430-445 ◽  
Author(s):  
Sarojini Naidoo ◽  
Steven Collings
Keyword(s):  
Mental Health ◽  
Suicidal Behaviour ◽  
Suicide Ideation ◽  
Psychological Theory ◽  
Interactive Effects ◽  
Future Research ◽  
Cross Sectional ◽  
Theoretical Predictions ◽  
Cross Sectional Design ◽  
Interpersonal Psychological Theory

Suicidality is a growing mental health problem, with statistics for South Africa being in line with global estimates. There has, however, been relatively little empirical advancement in the conceptualization of suicidal behaviour in recent years. Joiner’s interpersonal-psychological theory of suicidal behaviour is a relatively new theory that appears to hold promise for advancing our understanding of the mechanisms that underlie suicidal behaviour. The theory proposes that people die by suicide because they want to and because they can. This study sought to test two key hypotheses of the interpersonal-psychological theory of suicidal behaviour using a cross-sectional design and a sample of 239 mental health outpatients. Consistent with theoretical predictions, levels of suicidal ideation were significantly predicted by the interactive effects of high levels of thwarted belongingness and perceived burdensomeness in the presence of high levels of hopelessness in relation to both of these distressing states; with estimates of risk for suicide being most strongly predicted by the interactive effects of suicide ideation and an acquired capability for suicide. These findings are discussed in terms of their implications for theory, practice, and future research.

scholarly journals Perbedaan kadar hemoglobin pada remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Marianne C. Jacobus ◽  
Max F.J Mantik ◽  
Adrian . Umboh
Keyword(s):  
Analytical Study ◽  
Nutrition Status ◽  
P Value ◽  
Cross Sectional ◽  
Significant Difference ◽  
Good Nutrition ◽  
The Difference ◽  
Cross Sectional Design ◽  
And Gender ◽  
Main Component

Abstract: Haemoglobin is the main component of red blood cells that serves as a transporter of oxygen and carbon dioxide in the blood. The normal range of haemoglobin values can be used to determine the degree of anemia according to age and gender. Geographical condition such as altitude influences the haemoglobin value. This study aimed to obtain the difference of haemoglobin levels between teenagers with good nutrition status who live at the highland and those at the seaside. This was an observational analytical study with a cross sectional design. Samples were students with good nutrition status of SMPN 3 Tomohon (living at the highland) and those of SMP Kristen Nazaret Tuminting (living at the seaside). There were 60 students who met the inclusion criteria as follows: adolescent, good nutrition status, healthy, aged 13-15 years, lived at the highland or at the seaside ≥ 6 month, and willing to be performed blood examinations, and had been approved by their parents. The Mann-Whitney test for the difference between haemoglobin levels of the two groups showed a p value < 0,001. Conclusion: There was a very significant difference between haemoglobin levels of good nutrition teenagers who lived at the highland and at the seaside. Keywords: haemoglobin levels, good nutrition, teenagers, highland, seaside  Abstrak: Hemoglobin merupakan komponen utama sel darah merah dan berfungsi sebagai transporter oksigen dan karbon dioksida dalam darah. Batas normal nilai hemoglobin dapat digunakan untuk menetapkan derajat anemia, dengan distribusi usia dan jenis kelamin spesifik didasarkan pada sampel referensi sehat. Kondisi geografis, seperti ketinggian tempat dari permukaan laut menjadi faktor pertimbangan dalam distribusi nilai normal hemoglobin. Penelitian ini bertujuan untuk mendapatkan perbedaan kadar hemoglobin antara remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai. Jenis penelitian ini analitik-observasional dengan desain potong lintang. Sampel penelitian yaitu remaja gizi baik yang tinggal di pegunungan yaitu siswa SMPN 3 Tomohon dan yang di tepi pantai yaitu siswa SMP Kristen Nazaret Tuminting. Subjek penelitian berjumlah 60 remaja yang memenuhi kriteria inklusi yaitu gizi baik, sehat, berumur 13-15 tahun, berdomisili di pegunungan atau tepi pantai ≥6 bulan, bersedia dilakukan pemeriksaan darah, dan telah disetujui oleh orang tua. Data yang diperoleh dianalisis menggunakan uji Mann-Whitney dengan bantuan program SPSS. Hasil uji Mann-Whitney mengenai perbedaan kadar hemoglobin antara kedua kelompok menunjukkan nila p <0,001. Simpulan: Terdapat perbedaan yang sangat bermakna kadar hemoglobin remaja gizi baik yang tinggal di pegunungan dengan di tepi pantai.Kata kunci: kadar hemoglobin, remaja gizi baik, pegunungan, tepi pantai

scholarly journals Associations between psychoactive substance use and sensation seeking behavior among drivers in Norway

2019 ◽  
Author(s):  
Ragnhild Elén Gjulem Jamt ◽  
Hallvard Gjerde ◽  
Håvard Furuhaugen ◽  
Giovanni Romeo ◽  
Vigdis Vindenes ◽  
...  
Keyword(s):  
Substance Use ◽  
Sensation Seeking ◽  
Psychoactive Substance ◽  
Cross Sectional ◽  
Polydrug Use ◽  
The North ◽  
Seeking Behavior ◽  
Psychoactive Substance Use ◽  
Cross Sectional Design ◽  
Sensation Seeking Scale

Abstract BackgroundDrug use and risky driving is associated with sensation seeking. The aim of this study was to investigate the association between use of psychoactive substances and levels of the sensation seeking personality trait as measured with the Brief Sensation Seeking Scale 4 among drivers in Norway. MethodA cross-sectional design was applied to estimate the association between psychoactive substance use and sensation seeking behavior. Drivers in normal traffic were included in two roadside surveys: one in the north (September 2014 – October 2015) and the other in the south-east of Norway (April 2016 – April 2017). Oral fluid was analyzed for alcohol and psychoactive drugs, and data on sex, age and time of participation were recorded. Participants filled in the Brief Sensation Seeking Scale 4 questionnaire. ResultsA total of 8053 drivers were included, of which 32% were women and 62% were under 40 years. The prevalence of alcohol was 0.3%, stimulants 0.6%, tetrahydrocannabinol 1.4% and benzodiazepines and/or z-hypnotics 2.0% and polydrug use 0.6% Associations between the use of tetrahydrocannabinol or benzodiazepines and/or z-hypnotics and a low score on the “thrill and adventure seeking” domain of the Brief Sensation Seeking Scale 4 (OR = 1.723, 95% C.I. = 1.001- 2.966, p = 0.05) were found. Associations were also found between the use of stimulants and the highest scores on the “experience seeking” (OR = 2.085, 95% C.I. = 1.084-4.009, p = 0.028) and “disinhibition” (OR = 4.791, 95% C.I. =1.748-13.135, p = 0.002) domains of the Brief Sensation Seeking Scale 4. No associations were found between sensation seeking behavior and alcohol or polydrug use. ConclusionA high degree of sensation seeking was found among drivers who had used stimulants, in contrast to drives who had used tetrahydrocannabinol and benzodiazepines and/or z-hypnotics who showed a low degree of sensation seeking. The combination of sensation seeking behavior and the use of stimulants might lead to increased risky behavior and thus traffic crashes.

scholarly journals Sex Differences in Substance Use Disorders: A Neurobiological Perspective

2021 ◽  
Vol 2 ◽  
Author(s):  
Jennifer L. Cornish ◽  
Asheeta A. Prasad
Keyword(s):  
Substance Use ◽  
Sex Differences ◽  
Clinical Studies ◽  
Reward Processing ◽  
Future Research ◽  
Neural Structure ◽  
Patterns Of Use ◽  
Males And Females ◽  
Potential Impact ◽  
Advance Knowledge

Clinical studies provide fundamental knowledge of substance use behaviors (substance of abuse, patterns of use, relapse rates). The combination of neuroimaging approaches reveal correlation between substance use disorder (SUD) and changes in neural structure, function, and neurotransmission. Here, we review these advances, placing special emphasis on sex specific findings from structural neuroimaging studies of those dependent on alcohol, nicotine, cannabis, psychostimulants, or opioids. Recent clinical studies in SUD analyzing sex differences reveal neurobiological changes that are differentially impacted in common reward processing regions such as the striatum, hippocampus, amygdala, insula, and corpus collosum. We reflect on the contribution of sex hormones, period of drug use and abstinence, and the potential impact of these factors on the interpretation of the reported findings. With the overall recognition that SUD impacts the brains of females and males differentially, it is of fundamental importance that future research is designed with sex as a variable of study in this field. Improved understanding of neurobiological changes in males and females in SUD will advance knowledge underlying sex-specific susceptibility and the neurobiological impact in these disorders. Together these findings will inform future treatments that are tailor designed for improved efficacy in females and males with SUD.

scholarly journals The Role of Social Reward and Corticostriatal Connectivity in Substance Use

2020 ◽  
Author(s):  
Daniel Sazhin ◽  
Angelique Frazier ◽  
Caleb River Haynes ◽  
Camille Johnston ◽  
Iris Ka-Yi Chat ◽  
...  
Keyword(s):  
Substance Use ◽  
Social Context ◽  
Orbitofrontal Cortex ◽  
Strategic Behavior ◽  
Reward Processing ◽  
Reward Sensitivity ◽  
Social Reward ◽  
Neural Responses ◽  
Social Stimuli ◽  
Neuroimaging Study

This report describes an ongoing R03 grant that explores the links between trait reward sensitivity, substance use, and neural responses to social and nonsocial reward. Although previous research has shown that trait reward sensitivity and neural responses to reward are linked to substance use, whether this relationship is impacted by how people process social stimuli remains unclear. We are investigating these questions via a neuroimaging study with college-aged participants, using individual difference measures that examine the relation between substance use, social context, and trait reward sensitivity with tasks that measure reward anticipation, strategic behavior, social reward consumption, and the influence of social context on reward processing. We predict that substance use will be tied to distinct patterns of striatal dysfunction. Specifically, reward hyposensitive individuals will exhibit blunted striatal responses to social and non-social reward and enhanced connectivity with the orbitofrontal cortex; in contrast, reward hypersensitive individuals will exhibit enhanced striatal responses to social and non-social reward and blunted connectivity with the orbitofrontal cortex. We also will examine the relation between self-reported reward sensitivity, substance use, and striatal responses to social reward and social context. We predict that individuals reporting the highest levels of substance use will show exaggerated striatal responses to social reward and social context, independent of self-reported reward sensitivity. Examining corticostriatal responses to reward processing will help characterize the relation between reward sensitivity, social context and substance use while providing a foundation for understanding risk factors and isolating neurocognitive mechanisms that may be targeted to increase the efficacy of interventions.

scholarly journals The Relationship between Adolescent Rumination and Maternal Rumination, Criticism and Positivity

2017 ◽  
Vol 45 (3) ◽  
pp. 300-311 ◽  
Author(s):  
Jessica L. Douglas ◽  
Deirdre Williams ◽  
Shirley Reynolds
Keyword(s):  
Parenting Practices ◽  
Female Adolescent ◽  
Self Report ◽  
Future Research ◽  
Cross Sectional ◽  
Mothers And Daughters ◽  
Observational Measure ◽  
Cross Sectional Design ◽  
Prospective Longitudinal ◽  
The Relationship

Background: Rumination predicts depression in adults and adolescents. The development of rumination has been linked to parenting practices, but only limited research has investigated this and research has tended to rely on self-report parenting measures. Aims: To investigate the relationship between female adolescent rumination and maternal modelling, criticism and positivity using an observational measure of parental behaviour. Method: A cross-sectional design was used. Daughters aged 16–18 years and their mothers (n = 154 dyads) completed questionnaire measures of rumination and affect. Mothers of girls with rumination scores in the upper and lower quartile (both n = 26) also completed the Five Minute Speech Sample, which was used to measure maternal criticism and positivity. Results: Mothers of low rumination girls made significantly more positive comments about their daughters than the mothers of high ruminators. Mothers made very few critical comments. Self-reported rumination was not correlated in mothers and daughters, suggesting a lack of support for the potential role of modelling. Conclusion: Overall, low maternal positivity was associated with rumination in female adolescents. There was no evidence that maternal rumination or criticism were associated with adolescent rumination. The results suggest a number of implications for future research, including the need for prospective longitudinal studies using observational parenting measures.

A Scoping Review of Literature on Sex and Gender Differences Among Dementia Spousal Caregivers

2019 ◽  
Vol 59 (6) ◽  
pp. e802-e815 ◽  
Author(s):  
Ifah Arbel ◽  
Kathleen S Bingham ◽  
Deirdre R Dawson
Keyword(s):  
Gender Differences ◽  
Scoping Review ◽  
Policy Development ◽  
Empirical Studies ◽  
Spousal Caregivers ◽  
Future Research ◽  
Sex And Gender ◽  
Cross Sectional ◽  
And Gender ◽  
Sex And Gender Differences

Abstract Background and Objectives Sex and gender differences among dementia spousal caregivers have been investigated, but never systematically reviewed or synthesized. A synthesis of findings can help facilitate specificity in practice and in health policy development. As a first step towards such a synthesis, this scoping review reports the available evidence, identifies research gaps, and suggests possible directions for future research. Research Design and Methods A scoping review methodology was used to identify articles, and to chart and analyze data. Systematic searches for published, empirical studies, with an explicit goal or hypothesis related to sex or gender differences were conducted in seven databases. Results Sixty-one studies met inclusion criteria. Most (n = 45) were quantitative, cross-sectional studies. Caregivers included in the studies were generally 61–70 years old, Caucasian, middle-class, and highly educated. The most extensively investigated differences are: depression, burden, objective physical health, and informal supports. Discussion and Implications This scoping review is the first to summarize and critique the research on sex and gender differences that are specific to dementia spousal caregivers. The review can be used by researchers to make decisions regarding future systematic reviews and primary studies. To further strengthen the evidence base, future studies may benefit from including more caregivers of ethnic minorities, using more qualitative, longitudinal, or experimental designs, and focusing on variables needed to inform caregiving models and theories. Overall, this scoping review contributes to furthering gender-sensitive practices and policies that are better tailored to the specific needs of this population.

scholarly journals BASELINE DRIVING MILEAGE PREDICTS STATE-REPORTED CRASHES ACROSS 5 YEARS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S343-S343
Author(s):  
Junyan Tian ◽  
Sara A Freed ◽  
Lesley Ross
Keyword(s):  
Older Adults ◽  
Population Density ◽  
The United States ◽  
Future Research ◽  
Cross Sectional ◽  
Healthy Older Adults ◽  
Crash Data ◽  
Significant Difference ◽  
Cross Sectional Design ◽  
Testing Site

Abstract Although annual driving mileage has frequently been examined as a predictor of crashes among older adults, most research used cross-sectional design and relied on self-reported crash data. This study used multivariate regression to examine the number of state reported at-fault crashes between groups of low (14,000km) self-reported annual distance over five years. Additionally, key factors of interest including age, gender, and population density were examined as predictors. The sample included 519 healthy older adults aged 65-90 (M=73.17, SD=5.56) across five sites in the United States. 12% of participants experienced a crash across five years, and among those who crashed, the majority (87%) experienced one crash (range 0-3 crashes). After controlling for age, gender and testing site, people in the high annual mileage group had a greater number of crashes compared to the low mileage group (β=.14, t(513)=2.37, p=.02). There was not a significant difference in number of prospective crashes between the low and medium group. Also, people who drove in sites with low population density had more crashes than those who in high population density sites (β=.10, t(513)=2.24, p=.03). Higher age was associated with a greater number of prospective crashes (β=.01, t(513)=3.67, p =.002); however, gender was not a significant predictor of crashes. Our results highlight the importance of examining prospective crashes over time, and taking mileage and population density into consideration. Future research should examine trajectories of driving exposure in relation to prospective crashes using multilevel modeling.

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