scholarly journals The association between chronic airflow obstruction and poverty in 12 sites of the multinational BOLD study

2017 ◽  
Vol 49 (6) ◽  
pp. 1601880 ◽  
Author(s):  
John Townend ◽  
Cosetta Minelli ◽  
Kevin Mortimer ◽  
Daniel O. Obaseki ◽  
Mohammed Al Ghobain ◽  
...  

Poverty is strongly associated with mortality from COPD, but little is known of its relation to airflow obstruction.In a cross-sectional study of adults aged ≥40 years from 12 sites (N=9255), participating in the Burden of Obstructive Lung Disease (BOLD) study, poverty was evaluated using a wealth score (0–10) based on household assets. Obstruction, measured as forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) (%) after administration of 200 μg salbutamol, and prevalence of FEV1/FVC<lower limit of normal were tested for association with poverty for each site, and the results were combined by meta-analysis.Mean wealth scores ranged from 4 in Blantyre (Malawi) and Kashmir (India) to 10 in Riyadh (Saudi Arabia), and the prevalence of obstruction, from 16% in Kashmir to 3% in Riyadh and Penang (Malaysia). Following adjustments for age and sex, FEV1/FVC increased by 0.36% (absolute change) (95%CI: 0.22, 0.49; p<0.001) per unit increase in wealth score. Adjustments for other confounders reduced this effect to 0.23% (0.11, 0.34), but even this value remained highly significant (p<0.001). Results were consistent across sites (I2=1%; phet=0.44). Mean wealth scores explained 38% of the variation in mean FEV1/FVC between sites (r2=0.385, p=0.031).Airflow obstruction is consistently associated with poverty at individual and community levels across several countries.

2020 ◽  
Vol 7 (12) ◽  
pp. 1795
Author(s):  
Dhairya Salvi ◽  
Dhanvi Moradia

Background: Obesity is a chronic disease characterized by excessive body fat that causes damage to the individual’s health and is associated with comorbidities such as diabetes and hypertension and vascular dysfunction. This cross-sectional study was carried out with the objective of evaluating the effect of obesity on lung function test in obese but otherwise healthy adults.Methods: It was a cross-sectional study carried out at tertiary care institute of Gujarat, India. It was conducted over a period of 5 months. A total of 240 adult healthy subjects of both sexes were selected randomly belonging to varying socio-economic status. The study subjects were divided into 3 categories (normal body mass index i.e. BMI, overweight, obese). BMI were calculated for the randomly selected subjects from each list till the desired number in each BMI group were attained. Four respiratory parameters viz. forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), forced expiratory volume in 3 seconds (FEV3), and maximum voluntary ventilation (MVV) were used to assess their lung functions.Results: Two hundred and forty subjects (each group having n=80). The mean age of group I, group II and group III were 27.45±6.37, 28.18±6.42 and 28.98±6.74 respectively. Lung volumes showed significant difference in relation to the BMI. FVC and FEV1 show significant decrease. Group III verses group I (p˂0.001 and p˂0.017 respectively) FEV3 showed significant difference between group I and group III and between group II and group III (p˂0.001). MVV was significantly lower in group III when compared to group I.Conclusions: There is decline in pulmonary function in obese as compared to normal weight adults. These findings suggest deleterious effects on ventilatory mechanics caused by obesity, due to probable lung compression (reduction in the expiratory reserve volume i.e. ERV), leading to a compensatory increase in the inspiratory reserve volume (IRV) in an attempt to maintain a constant vital capacity (VC).


2020 ◽  
Vol 8 (B) ◽  
pp. 709-715
Author(s):  
Ni Luh Putu Eka Arisanti ◽  
Ni Putu Ayu Widiasari ◽  
Ida Bagus Ngurah Rai

AIM: The objective of the study was to determine chronic respiratory symptoms and lung function of farmers. METHODS: The study was conducted in Utu Village, Tabanan, Bali with 84 subjects. This research was observational analytic cross sectional study. RESULTS: Three dominant chronic respiratory symptoms in farmers were coughing (15.1%), dyspnea (13.1%), and phlegm (13.1%). Average values of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and FEV1/FVC were 83.75 ± 34.42, respectively, 81.62 ± 34.30 and 104.90 ± 13.90, respectively. Cough was dominant experiencing by smokers (p = 0.008). Mean of FEV1% prediction and FVC% prediction value was lower in passive smoker group than no smoker group (p = 0.005 and p = 0.03). CONCLUSION: Occupational exposure while farming and raising livestock can cause chronic respiratory symptom and lung function decline in farmers and can be influenced by smoking history and secondhand smoke exposure.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Un Chul Park ◽  
Eun Kyoung Lee ◽  
Bo Hee Kim ◽  
Baek-Lok Oh

AbstractIn this cross-sectional study, we investigated choroidal thickness (CT) and scleral thickness (ST) in highly myopic eyes and their associations with ocular factors. Patients underwent widefield swept-source optical coherence tomography (OCT) to measure the CT and ST at the subfovea and 3000 μm superior, inferior, temporal, and nasal to the fovea and macular curvature. A total of 237 eyes (154 patients) were included. At all five measurement points, thinner CTs and STs were associated with longer axial lengths (r = − 0.548 to − 0.357, all P < 0.001) and greater macular curvatures (r = − 0.542 to − 0.305, all P < 0.001). The CT and ST were significantly thinner in eyes with posterior staphyloma than in those without at all measurement points (all P ≤ 0.006) but did not differ between eyes with the wide macular and narrow macular type of staphyloma. Eyes with myopic maculopathy of category ≥ 3 according to the International Meta-Analysis for Pathologic Myopia classification had significantly thinner CTs and STs than those with category ≤ 2 (all P ≤ 0.005). In highly myopic eyes, a decrease in the CT and ST was more pronounced in eyes with more structural changes, such as longer axial length, steeper macular curvature, and the presence of posterior staphyloma.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Zaher Nazzal ◽  
Deema Odeh ◽  
Fatima Azahraa Haddad ◽  
Mohammad Berawi ◽  
Belal Rahhal ◽  
...  

Background. Waterpipe smoking in young individuals is increasing with limited studies addressing its respiratory health effects. The aim of the study was to determine the effect of waterpipe smoking on young adults’ lung functions. Spirometric parameters were compared between waterpipe smokers and nonsmokers. Methods. A comparative cross-sectional study of university students, including males and females, was conducted. An interviewer-administered questionnaire was used to record students’ characteristics. The spirometry test was performed to assess students’ lung functions; we recorded the forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), FEV1/FVC ratio, peak expiratory flow (PEF), and forced expiratory flow between 25 and 75% of FVC (FEF25–75%). Results. A total of 300 apparently healthy students (150 waterpipe smokers and 150 nonsmokers) were included in the study. Waterpipe smokers showed significantly lower values in FEV1, FEV1/FVC ratio, PEF, and FEF25–75% compared to the nonsmoker group (P<0.05 to P<0.001). The subgroup analysis on female students (50 WP smokers and 50 nonsmokers) showed a significant decrease in FEV1/FVC ratio, PEF, and FEF25–75% parameters (P<0.001). Conclusion. Waterpipe smoking is associated with reduced spirometric parameters in healthy young adults with relatively limited smoking years.


2021 ◽  
pp. 1-15
Author(s):  
Khemayanto Hidayat ◽  
Wan-Zhan Zhu ◽  
Si-Min Peng ◽  
Jin-Jin Ren ◽  
Meng-Lan Lu ◽  
...  

Abstract The findings regarding the associations between red meat, fish and poultry consumption, and the metabolic syndrome (Mets) have been inconclusive, and evidence from Chinese populations is scarce. A cross-sectional study was performed to investigate the associations between red meat, fish and poultry consumption, and the prevalence of the Mets and its components among the residents of Suzhou Industrial Park, Suzhou, China. A total of 4424 participants were eligible for the analysis. A logistic regression model was used to estimate the OR and 95 % CI for the prevalence of the Mets and its components according to red meat, fish and poultry consumption. In addition, the data of our cross-sectional study were meta-analysed under a random effects model along with those of published observational studies to generate the summary relative risks (RR) of the associations between the highest v. lowest categories of red meat, fish and poultry consumption and the Mets and its components. In the cross-sectional study, the multivariable-adjusted OR for the highest v. lowest quartiles of consumption was 1·23 (95 % CI 1·02, 1·48) for red meat, 0·83 (95 % CI 0·72, 0·97) for fish and 0·93 (95 % CI 0·74, 1·18) for poultry. In the meta-analysis, the pooled RR for the highest v. lowest categories of consumption was 1·20 (95 % CI 1·06, 1·35) for red meat, 0·88 (95 % CI 0·81, 0·96) for fish and 0·97 (95 % CI 0·85, 1·10) for poultry. The findings of both cross-sectional studies and meta-analyses indicated that the association between fish consumption and the Mets may be partly driven by the inverse association of fish consumption with elevated TAG and reduced HDL-cholesterol and, to a lesser extent, fasting plasma glucose. No clear pattern of associations was observed between red meat or poultry consumption and the components of the Mets. The current findings add weight to the evidence that the Mets may be positively associated with red meat consumption, inversely associated with fish consumption and neutrally associated with poultry consumption.


2020 ◽  
Vol 40 (2) ◽  
pp. 103-112
Author(s):  
Jerry Indra Setiawan ◽  
Suradi Suradi ◽  
Yusup Subagio Sutanto

Backgrounds: Professional divers have a greater lung volume than non-professional divers in higher force vital capacity (FVC) and force expiratory flow in 1 second (FEV1) values. The purpose of this study is to analyse the effect of pressure and duration of diving on changes in lung physiology in professional divers and non-professional divers. Methods: This is a cross sectional study on the personnel of the Indonesian Navy Dislambair Koarmada II Surabaya and RSAL personnel of dr. Ramelan Navy Hospital in Lakesla Surabaya in March-April 2019. Samples was collected with purposive sampling. This study used unpaired subjects with the independent t-test statistic analysis if the data is normally distributed and the Mann-Whitney U test if the data is not normally distributed Results: There was a significant difference in the professional divers group compared to non-professional divers group in the values of FVC (P=0.042) and FEV1 (P=0.040) at 1.3 ATA for 10 minutes and the FEV1 (P=0.049) for 20 minutes. No significant differences in FVC (P=0.092) at 1.3 ATA pressure for 20 minutes. There were no significant differences in FVC (P=0.865), FEV1 (P=0.659) at 1.5 ATA pressure for 10 minutes and FVC (P=0.858) and FEV1 (P=0.857) for 20 minutes. Conclusions: The different pressure in non-professional group could reduce the FEV1 value. There was a difference in the FVC value of the professional diver group and non-professional divers at a pressure of 1.5 ATA for 10 minutes. (J Respir Indo. 2020; 40(2): 103-12)


Author(s):  
Gurmeet Kaur ◽  
Sandeep Kaur ◽  
Geetika Gupta ◽  
Rajneet Kaur

Background: Obesity has long been recognized to have significant effect on respiratory functions. Many studies have reported exponential decrease in pulmonary function test (PFT) with increasing body mass index (BMI), which is a crude indicator of obesity. Also, the relationship between BMI and PFTs varies with age, race, geographical region and the different obesity standards used. To the best of our knowledge, not many studies have been done to examine the relationship between obesity and lung volumes among adults in our region, Jammu. This cross-sectional study was carried out with the objective of evaluating the effect of obesity on lung function test in obese but otherwise healthy adults of Jammu region.Methods: This cross-sectional study was conducted in Jammu region on subjects selected randomly from different colleges in the age group of 18-40 years. The study involved 300 subjects; divided into three groups of 100 each, based on BMI into normal, overweight and obese groups. Four respiratory parameters viz. FVC (Forced Vital Capacity), FEV1 (Forced Expiratory Volume in 1 second), FEV3 (Forced Expiratory Volume in 3 seconds), and MVV (Maximum Voluntary Ventilation) were used to assess their lung functions.Results: All the respiratory parameters exhibited statistically significant decrease in obese groups as compared to normal and overweight groups.Conclusions: The present study suggests that obesity alters the respiratory physiology by producing a restrictive ventilatory pattern.


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