scholarly journals Elevated dry-season malaria prevalence associated with fine-scale spatial patterns of environmental risk: a case–control study of children in rural Malawi

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Lindsay R Townes ◽  
Dyson Mwandama ◽  
Don P Mathanga ◽  
Mark L Wilson
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Felicitas Schulz ◽  
Ekkehart Jenetzky ◽  
Nadine Zwink ◽  
Charlotte Bendixen ◽  
Florian Kipfmueller ◽  
...  

Abstract Background Evidence for periconceptional or prenatal environmental risk factors for the development of congenital diaphragmatic hernia (CDH) is still scarce. Here, in a case-control study we investigated potential environmental risk factors in 199 CDH patients compared to 597 healthy control newborns. Methods The following data was collected: time of conception and birth, maternal BMI, parental risk factors such as smoking, alcohol or drug intake, use of hairspray, contact to animals and parental chronic diseases. CDH patients were born between 2001 and 2019, all healthy control newborns were born in 2011. Patients and control newborns were matched in the ratio of three to one. Results Presence of CDH was significantly associated with maternal periconceptional alcohol intake (odds ratio = 1.639, 95% confidence interval 1.101–2.440, p = 0.015) and maternal periconceptional use of hairspray (odds ratio = 2.072, 95% confidence interval 1.330–3.229, p = 0.001). Conclusion Our study suggests an association between CDH and periconceptional maternal alcohol intake and periconceptional maternal use of hairspray. Besides the identification of novel and confirmation of previously described parental risk factors, our study underlines the multifactorial background of isolated CDH.


2015 ◽  
Vol 40 (3) ◽  
pp. 113-117 ◽  
Author(s):  
A Jahan ◽  
SZR Rezina Parvin ◽  
D Bugum

This case-control study was done to identify the correlation between the familial, social and environmental risk factors and autism. This hospital and specialized centre based study done from January 2002 to November, 2004. Thirty two children from the autism group and 14 children from the control group were enrolled. Mean age were 3.75 yrs. and 2.83 yrs. respectively. Significant proportion of children were in the highest birth orders, 68.8% in autism and 78.6% in the control group. Full term children were 96.9% and 92.9% respectively. 53.1% children in the autism and 57.1% in the normal speech delay group were born by cesarean sections. Higher education of parents in autism group was statistically significant (p<0.05). Too much watching TV, inadequate opportunity to mix with peers and inadequate interactive relationship with the family members in the early childhood were significantly (p= 0.001) related to the development of autism.Bangladesh Med Res Counc Bull 2014; 40 (3): 113-117


2017 ◽  
Vol 38 (11) ◽  
pp. 1941-1951 ◽  
Author(s):  
Maryam Abbasi ◽  
Seyed Massood Nabavi ◽  
Seyed Mohammad Fereshtehnejad ◽  
Nikan Zerafat Jou ◽  
Iman Ansari ◽  
...  

1993 ◽  
Vol 12 (4) ◽  
pp. 209-218 ◽  
Author(s):  
Wen-zhi Wang ◽  
Xiang-hua Fang ◽  
Xue-ming Cheng ◽  
De-hua Jiang ◽  
Zhen-jian Lin

2009 ◽  
Vol 38 (4) ◽  
pp. 989-996 ◽  
Author(s):  
M. Hosseini ◽  
P. A. Naghan ◽  
S. Karimi ◽  
S. SeyedAlinaghi ◽  
M. Bahadori ◽  
...  

Rheumatology ◽  
2017 ◽  
Vol 56 (8) ◽  
pp. 1282-1292 ◽  
Author(s):  
Matthew Traylor ◽  
Charles Curtis ◽  
Hamel Patel ◽  
Gerome Breen ◽  
Sang Hyuck Lee ◽  
...  

2010 ◽  
Vol 39 (2) ◽  
pp. e35-e44 ◽  
Author(s):  
Valérie Spinelli ◽  
Olivier Chinot ◽  
Cécilia Cabaniols ◽  
Roch Giorgi ◽  
Philippe Alla ◽  
...  

2021 ◽  
Vol 9 ◽  
Author(s):  
Yinhua Feng ◽  
Xing Li ◽  
Zhenxing Mao ◽  
Wenqian Huo ◽  
Jian Hou ◽  
...  

Objective: The prevalence of type 2 diabetes mellitus (T2DM) varies greatly in different regions and populations. This study aims to assess the heritability and environmental risk factors of T2DM among rural Chinese adults.Methods: Thousand five hundred thirty three participants from 499 extended families, which included 24 nuclear families, were recruited in the family-based study to assess the heritable risk of T2DM. Heritability of T2DM was estimated by the Falconer method. Using conditional logistic regression model, couple case-control study involving 127 couples were applied to assess the environmental risk factors of T2DM.Results: Compared with the Henan Rural Cohort, T2DM was significantly clustered in the nuclear families (OR: 8.389, 95% CI: 5.537–12.711, P &lt; 0.001) and heritability was 0.74. No association between the heredity of T2DM and sex was observed between the extended families and the Henan Rural Cohort. Besides, results from the couple case-control study showed that physical activity (OR: 0.482, 95% CI: 0.261–0.893, P = 0.020) and fat intake (OR: 3.036, 95% CI: 1.070–8.610, P = 0.037) was associated with T2DM, and the proportion of offspring engaged in medium and high physical activity was higher than that of mothers in mother-offspring pairs.Conclusion: People with a family history of T2DM may have a higher risk of developing T2DM, however, there was no difference in genetic risk between males and females. Adherence to active physical activity and low fat intake can reduce the risk of T2DM.


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