scholarly journals The prevalence of psychological distress during pregnancy in Miyagi Prefecture for 3 years after the Great Eas t Japan Earthquake

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Kaou Tanoue ◽  
◽  
Zen Watanabe ◽  
Hidekazu Nishigori ◽  
Noriyuki Iwama ◽  
...  
Keyword(s):  
Mental Illness ◽  
Psychological Distress ◽  
Pregnant Women ◽  
Great East Japan Earthquake ◽  
The Other ◽  
Regional Center ◽  
Miyagi Prefecture ◽  
Disaster Data ◽  
Before And After ◽  
Regional Centers

Abstract Background To examine changes in psychological distress prevalence among pregnant women in Miyagi Prefecture, which was directly affected by the Great East Japan Earthquake and tsunami, and compare it with the other, less damaged areas of Japan. Methods This study was conducted in conjunction with the Japan Environment and Children`s Study. We examined 76,152 pregnant women including 8270 in Miyagi Regional Center and 67,882 in 13 other regional centers from the all-birth fixed data of the Japan Environment and Children’s Study. We then compared the prevalence and risk of distress in women in Miyagi Regional Center and women in the 13 regional centers for 3 years after the disaster. Results Women in the Miyagi Regional Center suffered more psychological distress than those in the 13 regional centers: OR 1.38 (95% CI, 1.03–1.87) to 1.92 (95% CI, 1.42–2.60). Additionally, women in the inland area had a consistently higher prevalence of psychological distress compared to those from the 13 regional centers: OR 1.67 (95% CI, 1.18–2.38) to 2.19 (95% CI, 1.60–2.99). Conclusions The lack of pre-disaster data in the Japan Environment and Children’s Study made it impossible to compare the incidence of psychological distress before and after the March 2011 Great East Japan Earthquake. However, 3 years after the Great East Japan Earthquake, the prevalence of pregnant women with psychological distress did not improve in Miyagi Regional Center. Further, the prevalence of mental illness in inland areas was consistently higher than that in the 13 regional centers after the disaster.

EFFECT OF INTRAVENOUS OR INTRA-AMNIOTIC INJECTION OF DEHYDROEPIANDROSTERONE SULPHATE ON OESTROGEN LEVELS IN URINE AND SERUM IN LATE PREGNANCY WITH LIVE ANENCEPHALIC FOETUSES

1976 ◽  
Vol 71 (3) ◽  
pp. 305-313 ◽  
Author(s):  
M. MAEYAMA ◽  
S. ICHIMARU ◽  
K. NAKAHARA ◽  
M. NAKAYAMA ◽  
I. MIYAKAWA
Keyword(s):  
Urinary Excretion ◽  
Pregnant Women ◽  
Late Pregnancy ◽  
Normal Pregnancy ◽  
The Other ◽  
Dehydroepiandrosterone Sulphate ◽  
Maximal Level ◽  
Control Value ◽  
Before And After ◽  
Urine And Serum

SUMMARY Dehydroepiandrosterone sulphate (DHAS) was injected intravenously or intra-amniotically into eight volunteers carrying live anencephalic foetuses (including one microcephalic foetus). Urinary and unconjugated serum oestrone, oestradiol and oestriol were measured before and after DHAS administration. In seven pregnant women with live anencephalic foetuses the urinary excretion of oestriol was very low, and the ratio of oestriol to oestrone+ oestradiol was much less than that during normal pregnancy. Increases of urinary oestrone and oestradiol but no significant change in the ratio of oestriol to oestrone + oestradiol were observed 24 h after i.v. administration of DHAS to five patients. In three patients, between 1 and 12 h after i.v. administration of DHAS (100–200 mg), the concentrations of serum oestrone, oestradiol and oestriol increased to 13·5, 6·8 and 3·1 times the control values, respectively. After injection of DHAS (200 mg) intra-amniotically into two patients, the urinary excretion of all three oestrogens increased much more on day 2 than on day 1, and the ratio of urinary oestriol to oestrone + oestradiol rose greatly. On the other hand, the concentrations of unconjugated serum oestrogens in these patients increased progressively between 1 and 12 h or more after DHAS administration, and the maximal level of serum oestriol was 9·8 times the control value while those of oestrone and oestradiol were 4·6 times and 5·0 times the control values, respectively. These results suggest that in late human pregnancy DHAS in the circulation of the mother is converted to oestriol largely via the phenolic pathway (DHAS → oestrone → oestriol), whereas DHAS circulating within the foeto-placental compartment is converted to oestriol via both the phenolic and the neutral intermediates.

Interannual Changes in the Prevalence of Intimate Partner Violence Against Pregnant Women in Miyagi Prefecture After the Great East Japan Earthquake: The Japan Environment and Children’s Study

2019 ◽  
pp. 088626051988151 ◽  
Author(s):  
Kaou Tanoue ◽  
Hidekazu Nishigori ◽  
Zen Watanabe ◽  
Kosuke Tanaka ◽  
Kasumi Sakurai ◽  
...  
Keyword(s):  
Intimate Partner Violence ◽  
Pregnant Women ◽  
Coastal Area ◽  
Partner Violence ◽  
Intimate Partner ◽  
Study Data ◽  
Great East Japan Earthquake ◽  
Physical Intimate Partner Violence ◽  
The North ◽  
Miyagi Prefecture

This study aimed to clarify the interannual changes in intimate partner violence against pregnant women after the March 11, 2011 Great East Japan Earthquake in target areas of Miyagi Prefecture that were damaged by the earthquake and tsunami. Because of this disaster, in Miyagi Prefecture, approximately 12,000 people died or went missing, and approximately 238,000 buildings were destroyed. According to the U.S. Geological Survey, the Great East Japan Earthquake is the fourth largest earthquake in the world and the largest in Japan since 1900. The present study was part of the Japan Environment and Children’s Study. Data from June 2011 to May 2014 of 79,222 pregnant women were analyzed, calculating the prevalence of physical and mental intimate partner violence in the inland, north coastal, and south coastal areas of Miyagi. These prevalence rates were compared with nationwide rates of intimate partner violence in 2011 using univariate and logistic regression analyses. After the disaster, the incidence of mental intimate partner violence increased in the south coastal area and then improved later (19.4%, 13.1%, and 13.3% for south coastal area, and 13.8%, 13.8%, and 13.1% for nationwide in 2011, 2012, and 2013, respectively). However, in the north coastal area, the incidence of physical intimate partner violence increased after the disaster and then improved later (2.7%, 1.5%, and 1.3% for north coastal area, and 1.4%, 1.3%, and 1.1% for nationwide in 2011, 2012, and 2013, respectively). In the inland area, however, the prevalence of both mental and physical intimate partner violence was consistently higher than nationwide rates after the disaster.

scholarly journals Cervical cancer screening rates before and after the Great East Japan Earthquake in the Miyagi Prefecture, Japan

PLoS ONE ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. e0229924
Author(s):  
Yasuhiro Miki ◽  
Toru Tase ◽  
Hideki Tokunaga ◽  
Nobuo Yaegashi ◽  
Kiyoshi Ito
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Great East Japan Earthquake ◽  
Miyagi Prefecture ◽  
Before And After

Impact of the Great East Japan Earthquake on Regional Obstetrical Care in Miyagi Prefecture

2016 ◽  
Vol 31 (3) ◽  
pp. 255-258 ◽  
Author(s):  
Junichi Sugawara ◽  
Tetsuro Hoshiai ◽  
Kazuyo Sato ◽  
Hideki Tokunaga ◽  
Hidekazu Nishigori ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Perinatal Outcomes ◽  
Great East Japan Earthquake ◽  
Obstetric Outcomes ◽  
Fire Departments ◽  
Publication Type ◽  
Obstetrical Care ◽  
Tsunami Disaster ◽  
Major Disaster ◽  
Miyagi Prefecture

AbstractObjectivesThe authors report the results of surveys on the emergency transport or evacuation status of obstetric patients conducted in Miyagi prefecture, one of the major disaster areas of the Great East Japan Earthquake and tsunami.MethodsThe surveys examined the damages to maternity institutions, evacuation status and transport of pregnant women, and prehospital childbirths and were conducted in 50 maternity institutions and 12 fire departments in Miyagi.ResultsTwo coastal institutions were destroyed completely, and four institutions were destroyed partially by the tsunami, forcing them to stop medical services. In the two-month period after the disaster, 217 pregnant women received hospital transport or gave birth after evacuation. Satisfactory perinatal outcomes were maintained. Emergency obstetric transport increased to approximately 1.4 fold the number before the disaster. Twenty-three women had prehospital childbirths, indicating a marked increase to approximately three times the number of the previous year.ConclusionIn the acute phase of the tsunami disaster, maternity institutions were damaged severely and perinatal transport was not possible; as a result, pregnant women inevitably gave birth in unplanned institutions, and the number of prehospital births was increased extremely. To obtain satisfactory obstetric outcomes, it is necessary to construct a future disaster management system and to re-recognize pregnant women as people with special needs in disaster situations.SugawaraJ, HoshiaiT, SatoK, TokunagaH, NishigoriH, AraiT, OkamuraK, YaegashiN. Impact of the Great East Japan Earthquake on regional obstetrical care in Miyagi Prefecture. Prehosp Disaster Med. 2016;31(3):255– 258.

scholarly journals Frequency of Macroprolactinemia Due to Autoantibodies against Prolactin in Pregnant Women

2001 ◽  
Vol 86 (2) ◽  
pp. 924-929 ◽  
Author(s):  
Dalila Pascoe-Lira ◽  
Genoveva Duran-Reyes ◽  
Iris Contreras-Hernández ◽  
Leticia Manuel-Apolinar ◽  
Francisco Blanco-Favela ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Pregnant Women ◽  
Molecular Mass ◽  
Chromatographic Separation ◽  
Protein A ◽  
Gel Filtration ◽  
Serum Levels ◽  
The Other ◽  
Positive Correlation ◽  
Before And After

The frequency of macroprolactinemia related to the presence of anti-PRL autoantibodies in the serum of 209 healthy women at different stages of pregnancy was studied. Measurements were taken of serum PRL concentrations before and after chromatographic separation (gel filtration and affinity with proteins A and G) and extraction of free PRL with polyethylene glycol (PEG). Sera from 8 of the 209 women (3.8%) were found to have a significantly high proportion of precipitated PRL by PEG (macroprolactinemia); in these patients, gel filtration showed that a substantial amount of big big PRL (molecular mass >100 kDa) was present (19.0–78.2% vs. 3.8–4.9%, P = 0.009 in normal pregnant women with a normal proportion of precipitated PRL by PEG). The presence of macroprolactinemia was attributable to anti-PRL autoantibodies in 5 of the 8 women. Comparison of serum levels of direct and free PRL between women with macroprolactinemia related to anti-PRL autoantibodies and women without macroprolactinemia showed significant differences (direct PRL: 270.2 ± 86.9 vs. 203.4 ± 69.0 μg/L, P = 0.04; and free PRL: 107.0 ± 75.9 vs. 173.3 ± 67.6 μg/L, P = 0.002). On the other hand, there was no difference between women with macroprolactinemia not related to anti-PRL autoantibodies and women with macroprolactinemia caused by anti-PRL autoantibodies, nor was there a difference between women with macroprolactinemia not related to anti-PRL autoantibodies and women without macroprolactinemia. There was a positive correlation between titers of the anti-PRL autoantibody and serum PRL levels (r = 0.82, P = 0.09). The presence of the anti-PRL autoantibody had no relation to the patient’s age, stage of gestation, or number of previous pregnancies. We concluded that the frequency of macroprolactinemia was 3.8% among healthy, pregnant women, which was caused by a anti-PRL autoantibodies in 62.5% of the cases. The autoantibodies were found in the bloodstream, forming a PRL-IgG complex, in accordance with the following observations: 1) immunoreactive PRL on gel filtration was eluted in the fractions corresponding to the molecular mass of IgG (150 kDa); 2) a significantly high proportion of immunoreactive PRL was retained on an affinity gel for IgG (proteins A and G); and 3) a significantly high proportion of serum PRL bound to IgG was precipitated by protein A. There was a positive correlation between titers of anti-PRL autoantibodies and serum PRL levels. Serum levels of total PRL were higher, and serum levels of free PRL were lower, in pregnant women with anti-PRL autoantibodies than in pregnant women without macroprolactinemia.

scholarly journals Role of Calcium Therapy on Urinary Calcium/Creatinine Ratio in Healthy Pregnant Women and Pre-eclamptic Women

1970 ◽  
pp. 7-9
Author(s):  
Sabiha Yasmin Moni ◽  
Mamun Rashid ◽  
Hosne Ara Begum ◽  
Sahin Ara ◽  
Nazimuddin Ahmed
Keyword(s):  
Pregnant Women ◽  
Urinary Calcium ◽  
The Other ◽  
Control Group ◽  
Creatinine Ratio ◽  
Normal Range ◽  
Urinary Creatinine ◽  
Before And After ◽  
Observational Group

The study has been carried out to observe the effect of calcium therapy on urinary calcium/creatinine ratio in healthy gravid women and pre-eclamptic women. Calcium/creatinine ratio has been considered for early detection of pre-eclamptic toxaemia (PET). So for the diagnosis of PET we try to investigate relation of urinary calcium, urinary creatinine, urinary calcium/creatinine ratio before and after calcium therapy. For this purpose total number of 60 healthy gravid and clinically suspected PET women of 20- 28 weeks of pregnancy having age ranged from, 17-39 years were selected. Of these 30 healthy pregnant women were taken as control group and another clinically diagnosed 30 PET women were taken as observational group. Urinary calcium/creatinine ratio was within normal range in healthy pregnant women and after calcium therapy this ratio was not significantly changed. On the other hand urinary calcium/creatinine ratio in PET women was significantly decreased and this ratio was significantly increased after calcium therapy. These observations suggest that low calcium/creatinine ratio help in early prediction of PET and calcium supplement during pregnancy may reduce the incidence of PET. DOI: 10.3329/bjpp.v25i1.5738Bangladesh J Physiol Pharmacol 2009; 25(1&2) : 7-9

scholarly journals Maternal Serum Levels of TNF-Alpha and IL-6 Long after Delivery in Preeclamptic and Normotensive Pregnant Women

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
N. Vitoratos ◽  
E. Economou ◽  
C. Iavazzo ◽  
K. Panoulis ◽  
G. Creatsas
Keyword(s):  
Pregnant Women ◽  
Serum Levels ◽  
Maternal Serum ◽  
The Other ◽  
Tnf Alpha ◽  
Blood Samples ◽  
Inflammatory Stress ◽  
Before And After ◽  
A Prospective Study ◽  
Normal Controls

Aim. To evaluate maternal TNF-alpha and IL-6 plasma levels in normotensive pregnant women, women with preeclampsia, and to examine the temporal changes in their levels from theantepartum to the postpartum period correlated with the regression of preeclampsia.Method. A prospective study was performed in the 2nd Department of Obstetrics and Gynecology, University of Athens. Blood samples were obtained: (1) antepartum at the time of clinical diagnosis of the syndrome, 2. 12-14 weeks postpartum.Results. No statistically significant differences were found in IL-6 levels, whereas a difference was found in TNF-alpha levels between preeclamptic and controls in antepartum period (0.80 pg/ml versus 0.60 pg/ml, ). Long after delivery, TNF-alpha levels were significantly higher in preeclamptic compared to normotensive controls (0.86 pg/ml versus 0.60 pg/ml, ). No difference was observed in TNF-alpha before and after delivery in both groups. No difference was noticed in IL-6 levels in women of normotensive group long after delivery compared to that before delivery. Long after delivery IL-6 levels were statistically significant higher in preeclamptic women compared to normal controls (3.53 ± 0.52 pg/ml versus 1.69 ± 0.48 pg/ml, ).Conclusion. Preeclamptic women remain under a status of increased inflammatory stress up to 12-14 weeks postpartum despite the fact that all the other signs of preeclampsia are resolved.

scholarly journals Evaluation of the Acceptability of a Prenatal Program for Women With Histories of Childhood Trauma: The Program STEP

2021 ◽  
Vol 12 ◽  
Author(s):  
Nicolas Berthelot ◽  
Christine Drouin-Maziade ◽  
Julia Garon-Bissonnette ◽  
Roxanne Lemieux ◽  
Thibaut Sériès ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Pregnant Women ◽  
Childhood Trauma ◽  
Group Intervention ◽  
Phase 1 ◽  
Early Life Adversity ◽  
Before And After ◽  
Program Step ◽  
High Level ◽  
Prenatal Interventions

Background: Childhood trauma would negatively affect pregnant women's mental health and would have intergenerational repercussions. However, there is a paucity of prenatal interventions specifically designed for women exposed to childhood trauma. The study aims to evaluate the acceptability of STEP, a manualized group intervention designed for pregnant women having experienced early life adversity.Methods: The acceptability of STEP was assessed in four phases. In Phase 1, six experts evaluated whether the program activities were pertinent and trauma sensitive. In Phase 2, three parents read the intervention manuals and evaluated whether they considered each session relevant, interesting, and clear. In Phase 3, the program was briefly presented by phone to 309 pregnant women from the community. Women were inquired about their interest in the program, and the reasons for their lack of interest were assessed. In Phase 4, 30 pregnant women exposed to childhood trauma participated in the program and completed anonymous satisfaction questionnaires after each session. Psychological distress was also measured before and after the program.Results: All activities were rated by independent experts as highly pertinent, adequate, and sufficiently safe to be offered to pregnant women. Parents who read through the intervention manuals also considered that the sessions were relevant, clear, and interesting. About half of the pregnant women from the community showed interest in the program. Participants reported very high levels of satisfaction and a significant decrease in psychological distress during the program.Conclusions: Our findings show a high level of convergence among various indicators of program acceptability.

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