scholarly journals Esmraldi: efficient methods for the fusion of mass spectrometry and magnetic resonance images

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Florent Grélard ◽  
David Legland ◽  
Mathieu Fanuel ◽  
Bastien Arnaud ◽  
Loïc Foucat ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Magnetic Resonance ◽  
Mass Spectrometry Imaging ◽  
Magnetic Resonance Images ◽  
Exploratory Research ◽  
Efficient Manner ◽  
Biological Images ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri ◽  
Similar Intensity

Abstract Background Mass spectrometry imaging (MSI) is a family of acquisition techniques producing images of the distribution of molecules in a sample, without any prior tagging of the molecules. This makes it a very interesting technique for exploratory research. However, the images are difficult to analyze because the enclosed data has high dimensionality, and their content does not necessarily reflect the shape of the object of interest. Conversely, magnetic resonance imaging (MRI) scans reflect the anatomy of the tissue. MRI also provides complementary information to MSI, such as the content and distribution of water. Results We propose a new workflow to merge the information from 2D MALDI–MSI and MRI images. Our workflow can be applied to large MSI datasets in a limited amount of time. Moreover, the workflow is fully automated and based on deterministic methods which ensures the reproducibility of the results. Our methods were evaluated and compared with state-of-the-art methods. Results show that the images are combined precisely and in a time-efficient manner. Conclusion Our workflow reveals molecules which co-localize with water in biological images. It can be applied on any MSI and MRI datasets which satisfy a few conditions: same regions of the shape enclosed in the images and similar intensity distributions.

Imaging-based stereotaxic serial biopsies in untreated intracranial glial neoplasms

1987 ◽  
Vol 66 (6) ◽  
pp. 865-874 ◽  
Author(s):  
Patrick J. Kelly ◽  
Catherine Daumas-Duport ◽  
David B. Kispert ◽  
Bruce A. Kall ◽  
Bernd W. Scheithauer ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Contrast Enhancement ◽  
Tumor Tissue ◽  
Magnetic Resonance Images ◽  
Low Grade ◽  
Content Type ◽  
Mri Scans ◽  
Isolated Tumor Cell ◽  
Magnetic Resonance Imaging Mri ◽  
Ct And Mri

✓ Forty patients with previously untreated intracranial glial neoplasms underwent stereotaxic serial biopsies assisted by computerized tomography (CT) and magnetic resonance imaging (MRI). Tumor volumes defined by computer reconstruction of contrast enhancement and low-attenuation boundaries on CT and T1 and T2 prolongation on MRI revealed that tumor volumes defined by T2-weighted MRI scans were larger than those defined by low-attenuation or contrast enhancement on CT scans. Histological analysis of 195 biopsy specimens obtained from various locations within the volumes defined by CT and MRI revealed that: 1) contrast enhancement most often corresponded to tumor tissue without intervening parenchyma; 2) hypodensity corresponded to parenchyma infiltrated by isolated tumor cells or in some instances to tumor tissue in low-grade gliomas or to simple edema; and 3) isolated tumor cell infiltration extended at least as far as T2 prolongation on magnetic resonance images. This information may be useful in planning surgical procedures and radiation therapy in patients with intracranial glial neoplasms.

scholarly journals Artifacts in MRI: Villain or Hero? Using Artifacts for Diagnosing Central Nervous System Diseases

2021 ◽  
Author(s):  
Gabriela Lopes de Morais ◽  
Gilmar Filho Peruzini ◽  
Marcos Rosa-Júnior
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Magnetic Resonance ◽  
Magnetic Resonance Images ◽  
Original Structure ◽  
Mri Scans ◽  
Final Interpretation ◽  
Pathologic Lesions ◽  
Picture Archiving And Communication ◽  
Magnetic Resonance Imaging Mri

AbstractAn artifact is a feature present in an image which is not part of the original structure. It can occur as a consequence of several factors. It may be mistaken for pathologic conditions, leading to adverse consequences for the patients. The aim of the present study is to present a selection of the main artifacts described in brain and spinal magnetic resonance images to improve the ability of the physicians to recognize them and to reduce their interference on the final interpretation of a scan. The authors searched the scientific community for artifacts in magnetic resonance imaging (MRI), which were selected to focus on central nervous system (CNS) findings. With the Picture Archiving and Communication System (PACS) database from the center where this study was conducted, the authors designated brain and spine MRI scans with conspicuous artifacts to compose the present study. The artifacts were then classified as those that contribute to the diagnosis and those that must be distinguished from pathologic lesions. Considering the novel classification proposed by the present study, physicians might be stimulated to reevaluate their opinions regarding artifacts, perhaps considering them helpful to evaluate certain conditions even if they cannot be fully corrected, as shown by this distinct approach to artifacts with specific findings concerning differential diagnosis of CNS conditions.

scholarly journals Automated 2D Segmentation of Prostate in T2-weighted MRI Scans

2016 ◽  
Vol 12 (1) ◽  
pp. 53
Author(s):  
Justinas Jucevicius ◽  
Povilas Treigys ◽  
Jolita Bernataviciene ◽  
Ruta Briediene ◽  
Ieva Naruševiciute ◽  
...  
Keyword(s):  
Image Segmentation ◽  
Magnetic Resonance ◽  
Automatic Segmentation ◽  
Magnetic Resonance Images ◽  
Mr Image ◽  
Prostate Segmentation ◽  
Image Appearance ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri ◽  
Mr Image Segmentation

The prostate cancer is the second most frequent tumor amongst men. Statistics shows that biopsy reveals only 70-80% clinical cancer cases. Multiparametric magnetic resonance imaging (MRI) technique comes to play and is used to help to determine the location to perform a biopsy. With the aim to automating the biopsy localization, prostate segmentation has to be performed in magnetic resonance images. Computer image analysis methods play the key role here. The problem of automated prostate magnetic resonance (MR) image segmentation is burdened by the fact that MRI signal intensity is not standardized: field of view and image appearance is for a large part determined by acquisition protocol, field strength, coil profile and scanner type. Authors overview the most recent Prostate MR image segmentation challenge results and provide insights on T2-weighted MRI scan images automated prostate segmentation problem by comparing the best obtained automatic segmentation algorithms and applying them to 2D prostate segmentation case. The most important benefit of this research will have medical doctors involved in the management of the cancer.

An emerging technology: Nuclear magnetic resonance microscopy

1988 ◽  
Vol 46 ◽  
pp. 1000-1001
Author(s):  
M.J. Hennessy ◽  
E. Kwok
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Relaxation Times ◽  
Basic Research ◽  
Local Environment ◽  
Magnetic Resonance Images ◽  
Nmr Microscopy ◽  
Mri Scans ◽  
Temperature Relaxation ◽  
Nuclear Magnetic

Much progress in nuclear magnetic resonance microscope has been made in the last few years as a result of improved instrumentation and techniques being made available through basic research in magnetic resonance imaging (MRI) technologies for medicine. Nuclear magnetic resonance (NMR) was first observed in the hydrogen nucleus in water by Bloch, Purcell and Pound over 40 years ago. Today, in medicine, virtually all commercial MRI scans are made of water bound in tissue. This is also true for NMR microscopy, which has focussed mainly on biological applications. The reason water is the favored molecule for NMR is because water is,the most abundant molecule in biology. It is also the most NMR sensitive having the largest nuclear magnetic moment and having reasonable room temperature relaxation times (from 10 ms to 3 sec). The contrast seen in magnetic resonance images is due mostly to distribution of water relaxation times in sample which are extremely sensitive to the local environment.

scholarly journals Magnetic resonance imaging (MRI) scans in patients with dorsal root ganglion stimulation

Pain Practice ◽  
2021 ◽  
Author(s):  
Marco Reining ◽  
Dirk Winkler ◽  
Joachim Boettcher ◽  
Juergen Meixensberger ◽  
Michael Kretzschmar
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Dorsal Root Ganglion ◽  
Dorsal Root ◽  
Resonance Imaging ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri

Safety Issues in Magnetic Resonance Imaging Scan with Retention of Olympus Long Clips in the Gastrointestinal Tract

2021 ◽  
Vol 17 ◽  
Author(s):  
Cheng-Yi Wang ◽  
Wei-Chou Chang ◽  
Hsin-Hung Huang ◽  
Wei-Kuo Chang ◽  
Yu-Lueng Shih ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Resonance Imaging Scan ◽  
Resonance Imaging ◽  
Endoscopic Clip ◽  
Serious Adverse Event ◽  
Safety Issues ◽  
Endoscopic Clips ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri

Objective: Not all endoscopic clips are compatible with magnetic resonance imaging (MRI). The aim of this study is to investigate the safety of MRI-incompatible endoscopic clips in patients undergoing MRI scans. Methods: We retrospectively reviewed the medical records of patients who had received endoscopic clip placement of Olympus Long Clip MRI-incompatible clips and then had undergone MRI scans within two weeks in our hospital between 2014 and 2019. Results: A total of 44,292 patients had undergone an MRI examination at our hospital. Only 15 patients had MRI scans within two weeks after the endoscopic clip placement. Their median age was 65.5 years, and 12 of the 15 patients were men. At the time of the clip placement and MRI scan, four patients were taking anti-coagulation or anti-platelet agents. The indication for endoscopic clip placement of the 15 patients was mucosal/submucosal defect or hemorrhage and colonic perforation. Endoscopic clips were placed in the colon of 14 patients and in the stomach of only one patient for gastric hemorrhage. One patient experienced clip migration and three displayed artifacts in abdominal images. No patient complications of mortality, hemorrhage, or organ perforation occurred. Conclusion: No serious adverse event occurred during MRI scans of patients with MRI-incompatible clips in this study, suggesting that MRI-incompatible clips may be safe to use in MRI scans. However, this does not guarantee the safety of the Long Clip for MRI scans, as further tests are needed to verify that this clip is safe for use during MRI.

Magnetic Resonance Imaging to Investigate the Clinical Applicability of the Medial Femoral Trochlea Osteochondral Flap Within the Wrist

Hand ◽  
2022 ◽  
pp. 155894472110643
Author(s):  
Jimmy H. Daruwalla ◽  
Jan Skrok ◽  
Mitchell A. Pet ◽  
Aviram M. Giladi ◽  
James P. Higgins
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Sagittal Plane ◽  
Convex Surface ◽  
Radius Of Curvature ◽  
Resonance Imaging ◽  
Femoral Trochlea ◽  
Average Ratio ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri

Background: The medial femoral trochlea (MFT) osteochondral flap is employed for reconstruction of unsalvageable scaphoid proximal pole nonunions. The convex surface of the cartilage-bearing proximal trochlea is used to replace the similarly contoured proximal scaphoid and articulate with the concave scaphoid fossa of the radius. A magnetic resonance imaging (MRI) comparison of the shape of the MFT as it relates to the native proximal scaphoid has not been previously performed. Our study aimed to quantifiably compare the shape of the MFT, proximal scaphoid, and scaphoid fossa. Methods: Using imaging processing software, we measured radius of curvature of the articular segments in MRI scans of 10 healthy subjects’ wrists and knees. Results: Compared with the scaphoid fossa, average ratio of the radius of circumference of the proximal scaphoid was 0.79 and 0.78 in the coronal and sagittal planes, respectively. Compared with the scaphoid fossa, average ratio of the radius of circumference of the MFT was 0.98 and 1.31 in the coronal and sagittal planes, respectively. The radius of curvature of the MFT was larger than the proximal scaphoid, in the coronal and sagittal planes. In the coronal plane, the MFT radius of curvature is nearly identical to the scaphoid fossa, a closer match than the scaphoid itself. In the sagittal plane, the radius of curvature of the MFT was larger than the radius of curvature of the scaphoid fossa. Conclusions: Our data suggest that the radius of curvature, in the sagittal and coronal planes, of the MFT and proximal scaphoid is disparate.

scholarly journals Sensitivity of Magnetic Resonance Imaging in the Detection of Colorectal Liver Metastases

2008 ◽  
Vol 90 (1) ◽  
pp. 25-28 ◽  
Author(s):  
S Blyth ◽  
A Blakeborough ◽  
M Peterson ◽  
IC Cameron ◽  
AW Majeed
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Imaging Modality ◽  
Invasive Technique ◽  
Resonance Imaging ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri ◽  
High Degree

INTRODUCTION The aim of this study was to evaluate the sensitivity of magnetic resonance imaging (MRI) in the detection of colorectal liver metastases. PATIENTS AND METHODS Pre-operative MRI scanning of the liver was performed by a single radiologist and the size and number of definite liver metastases were recorded. Patients then underwent hepatectomy with routine intra-operative ultrasonography (IOUS) and resected specimens were sent for histopathology. Pathology findings were compared with those of MRI scans to determine the sensitivity of this imaging modality. Exclusions were patients undergoing hepatic resection more than 4 weeks after the MRI scan, those undergoing chemotherapy at the time of the scan, and those with conglomerate unilobar metastases. RESULTS Complete data were available for 84 patients. There was total agreement between MRI, IOUS and histology in 79 patients (101 metastases). MRI missed 5 metastases in 5 patients that were found on IOUS (or palpation of superficial lesions) and subsequently confirmed by histological examination. These measured 5 mm or less (4 patients) and 7 mm (one patient). The sensitivity of MRI in the detection of colorectal liver metastases was thus 94% for all lesions and 100% for lesions 1 cm or larger in diameter. CONCLUSIONS MRI of the liver is a non-invasive technique with an extremely high degree of sensitivity in the detection of colorectal liver metastases and should be considered as the ‘gold standard’ in the pre-operative imaging of these patients.

“Moustache” Appearance in Craniopharyngiomas: Unique Magnetic Resonance Imaging and Computed Tomographic Findings of Perifocal Edema

Neurosurgery ◽  
1990 ◽  
Vol 27 (6) ◽  
pp. 993-996 ◽  
Author(s):  
Sotaro Higashi ◽  
Junkoh Yamashita ◽  
Hirosuke Fujisawa ◽  
Yuuichi Yamamoto ◽  
Masumi Kadoya
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Intraventricular Tumor ◽  
Resonance Imaging ◽  
Computed Tomographic ◽  
Perifocal Edema ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri ◽  
Operative Findings ◽  
Protein Rich

Abstract This report describes two cases of craniopharyngioma with perifocal edema. In both patients, computed tomography and magnetic resonance imaging (MRI) revealed that the tumors occupied the suprasellar cistern, invaginated the floor of the 3rd ventricle and were tightly adherent to the ventricular walls. The intraventricular portions of the tumors were cystic, containing protein-rich fluid as suggested by MRI and confirmed by operative findings. There was perifocal edema in the hypothalamus adjacent to the intraventricular tumor, the optic tracts, and the posterior limbs of the internal capsules, resembling the shape of a moustache on axial computed tomographic and MRI scans. The perifocal edema subsided after treatment of the intraventricular tumor by surgical resection or radiation therapy. The “moustache” appearance seems a unique, characteristic feature of perifocal edema, which is observed infrequently with certain craniopharyngiomas.

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