scholarly journals Functional glyco-metagenomics elucidates the role of glycan-related genes in environments

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Hayato Takihara ◽  
Nobuaki Miura ◽  
Kiyoko F. Aoki-Kinoshita ◽  
Shujiro Okuda

Abstract Background Glycan-related genes play a fundamental role in various processes for energy acquisition and homeostasis maintenance while adapting to the environment in which the organism exists; however, their role in the microbiome in the environment is unclear. Methods Sequence alignment was performed between known glycan-related genes and complete genomes of microorganisms, and optimal parameters for identifying glycan-related genes were determined based on the alignments. Using the constructed scheme (> 90% of identity and > 25 aa of alignment length), glycan-related genes in various environments were identified from 198 different metagenome data. Results As a result, we identified 86.73 million glycan-related genes from the metagenome data. Among the 12 environments classified in this study, the percentage of glycan-related genes was high in the human-associated environment, suggesting that these environments utilize glycan metabolism better than other environments. On the other hand, the relative abundances of both glycoside hydrolases and glycosyltransferases surprisingly had a coverage of over 80% in all the environments. These glycoside hydrolases and glycosyltransferases were classified into two groups of (1) general enzyme families identified in various environments and (2) specific enzymes found only in certain environments. The general enzyme families were mostly from genes involved in monosaccharide metabolism, and most of the specific enzymes were polysaccharide degrading enzymes. Conclusion These findings suggest that environmental microorganisms could change the composition of their glycan-related genes to adapt the processes involved in acquiring energy from glycans in their environments. Our functional glyco-metagenomics approach has made it possible to clarify the relationship between the environment and genes from the perspective of carbohydrates, and the existence of glycan-related genes that exist specifically in the environment.

2014 ◽  
Vol 4 (2) ◽  
Author(s):  
Tamara Feldman

This paper is a contribution to the growing literature on the role of projective identification in understanding couples' dynamics. Projective identification as a defence is well suited to couples, as intimate partners provide an ideal location to deposit unwanted parts of the self. This paper illustrates how projective identification functions differently depending on the psychological health of the couple. It elucidates how healthier couples use projective identification more as a form of communication, whereas disturbed couples are inclined to employ it to invade and control the other, as captured by Meltzer's concept of "intrusive identification". These different uses of projective identification affect couples' capacities to provide what Bion called "containment". In disturbed couples, partners serve as what Meltzer termed "claustrums" whereby projections are not contained, but imprisoned or entombed in the other. Applying the concept of claustrum helps illuminate common feelings these couples express, such as feeling suffocated, stifled, trapped, held hostage, or feeling as if the relationship is killing them. Finally, this paper presents treatment challenges in working with more disturbed couples.


1995 ◽  
Vol 31 (9) ◽  
pp. 137-144 ◽  
Author(s):  
T. Miyahara ◽  
M. Takano ◽  
T. Noike

The relationship between the filter media and the behaviour of anaerobic bacteria was studied using anaerobic fixed-bed reactors. At an HRT of 48 hours, the number of suspended acidogenic bacteria was higher than those attached to the filter media. On the other hand, the number of attached methanogenic bacteria was more than ten times as higher than that of suspended ones. The numbers of suspended and deposited acidogenic and methanogenic bacteria in the reactor operated at an HRT of 3 hours were almost the same as those in the reactor operated at an HRT of 48 hours. Accumulation of attached bacteria was promoted by decreasing the HRT of the reactor. The number of acidogenic bacteria in the reactor packed sparsely with the filter media was higher than that in the closely packed reactor. The number of methanogenic bacteria in the sparsely packed reactor was lower than that in the closely packed reactor.


2021 ◽  
Vol 1 (1) ◽  
pp. 99-112
Author(s):  
Richard Larouche ◽  
Nimesh Patel ◽  
Jennifer L. Copeland

The role of infrastructure in encouraging transportation cycling in smaller cities with a low prevalence of cycling remains unclear. To investigate the relationship between the presence of infrastructure and transportation cycling in a small city (Lethbridge, AB, Canada), we interviewed 246 adults along a recently-constructed bicycle boulevard and two comparison streets with no recent changes in cycling infrastructure. One comparison street had a separate multi-use path and the other had no cycling infrastructure. Questions addressed time spent cycling in the past week and 2 years prior and potential socio-demographic and psychosocial correlates of cycling, including safety concerns. Finally, we asked participants what could be done to make cycling safer and more attractive. We examined predictors of cycling using gender-stratified generalized linear models. Women interviewed along the street with a separate path reported cycling more than women on the other streets. A more favorable attitude towards cycling and greater habit strength were associated with more cycling in both men and women. Qualitative data revealed generally positive views about the bicycle boulevard, a need for education about sharing the road and for better cycling infrastructure in general. Our results suggest that, even in smaller cities, cycling infrastructure may encourage cycling, especially among women.


Proceedings ◽  
2021 ◽  
Vol 77 (1) ◽  
pp. 15
Author(s):  
Hernan Mondani ◽  
Amir Rostami ◽  
Tina Askanius ◽  
Jerzy Sarnecki ◽  
Christofer Edling

This presentation summarizes a register-based study on women who have been identified as belonging to three violent extremist milieus in Sweden: violent Islamic, violent far-right, and violent far-left extremism. We studied the women in these milieus along a number of analytical dimensions, ranging from demographic and educational to criminal background and network relationships, and compared them to three reference groups: (i) non-extremist biological sisters to female extremists in the study population; (ii) men in the respective extremist milieus; and (iii) female members of other antagonistic milieus such as organized crime. Our results showed that there are both similarities and differences between groups. In some cases, like age and region of birth, there are commonalities between violent far-right and violent far-left women. Regarding region of birth and migration background, women affiliated to violent far-right and violent far-left extremism are predominantly born in Sweden. Women affiliated to violent Islamic extremism tend to be born in Sweden to a greater extent than men in the same milieu, but to a much lesser degree than women in the violent far-right and violent far-left. When it comes to education, women in the violent Islamic milieu are closer to women in violent far-right extremism. Women in violent far-left extremism perform best at school, with consistently higher grades. The average score of women in violent far-left extremism is identical to that of their sisters, and women in violent far-left extremism perform on average substantially better than men in the same milieu. Women in violent Islamic extremism, in contrast, perform on average similarly to men in violent far-left extremism, and they perform better than their biological sisters. Regarding labor market attachment, violent Islamic extremists have the weakest attachment and the highest dependency upon financial assistance as well as a low employment share (36 percent in 2016), but also a relatively high share of individuals with a high number of unemployment days, suggesting that women in violent Islamic extremism experience higher social exclusion. We find the highest employment share among women in violent far-left extremism, where 89 percent are gainfully employed in 2016 (80 percent for at least three of the last five years) and about a 20 percent unemployment share. Men in violent far-left extremism have an employment share around 10 percent below that of the women in far-left extremism for 2016. The highest fractions of individuals that have not been in contact with the health system due to mental disorders are among violent Islamic extremism, with the women’s fraction at 84 percent, compared to their non-extremist sisters and men in the same milieu that are just above 79 percent. Women in violent far-left extremism have the highest share of in-patient major mental disorders among the extremist milieus (3 percent), higher than men in the same milieu (less than 1 percent) as well as than women and their sisters in the other categories. During the period 2007–2016, 68 percent of individuals in the extremist milieus are covered by the register of suspected individuals. The coverage is substantially higher for men, 72 percent than for women, 43 percent. Compared to their sisters, women in all three milieus are criminally active to a much higher extent. However, women in all three milieus are less criminally active than women in other antagonistic milieus, among whom 67 percent have been suspected at least once. In all three milieus, the share of men with a criminal record is about twice as large as that of women. As far as the gender aspect is concerned, we know that extremist milieus generally have a conservative view of the role of women in society. In our results, this is reflected in the low rates of crime in women compared to men, and relatively marginal positions in the co-offending networks. The fact that women in violent far-left extremism have stronger positions in their networks than the other women in the study population is expected, given that the ideology of this milieu allows for greater equality. This means that women in violent far-left extremism participate more often than, e.g., women in violent far-right extremism, in political actions where violence is common. This pattern of gender roles and criminal involvement also holds concerning women in violent Islamic extremism. This milieu has a more traditional view of the role of women than views among even violent far-right extremists. Women in violent Islamic extremism are less involved in crime and, in particular, violent crime.


2010 ◽  
Vol 28 (1) ◽  
pp. 83-99 ◽  
Author(s):  
Linda K. Ko ◽  
Megan A. Lewis

The present study investigated whether perception of receiving emotional support mediates the relationship between one partner’s giving of emotional support and the other partner’s depressive symptomatology using a population-based sample of 423 couples from the Changing Lives of Older Couples study. A path model was used guided by the Actor—Partner Interdependence Model. Results indicated that spouses’ giving emotional support was related to the degree to which their spouse reported receiving emotional support. Perception of receiving emotional support, in turn, was related to lower depressive symptomatology of the support recipient. Both husbands and wives can benefit from emotional support through their perception of receiving emotional support, and spouses’ perceptions, as well as their actions, should be considered in support transactions.


1998 ◽  
Vol 47 (3-4) ◽  
pp. 153-160
Author(s):  
S. A. Gruszewska

AbstractTaking into consideration two facts: that the structure of social life forces twins to part and that the presented roles in a pair are not equal, (one of the twins plays the role of a leader (L) and the other, the subordinate (P.)), one can ask the question — what meaning does the moment of parting have and what are its consequences?In order to do that, a survey was conducted, (a sample of 31 pairs of twins above the age of 30), in which every pair was asked the question: “Which one of you made the decision about parting?” The answer had two options: A – I, B – brother/sister. Out of 31 pairs of twins, 16 pairs chose the variant different from his brother or sister – that is A, B, admitting that the interpersonal conflict was the result of the parting. In 7 pairs, both twins chose the B variant – they withdrew from the conflict; and in 8 pairs they chose the A variant – looking for a compromise as the means of agreement.When analyzing the results of the survey, we can state the following:– in the relationship of twins, there is an interpersonal conflict;– the decision about parting is difficult with prevalent feelings of sadness and sorrow;– after parting, at least one of the twins has problems with preserving his identity and integrity of psychological space.Since the moment of parting is necessary and difficult, specialists and mainly parents are required to consciously change their position towards the relationship of twins. It has to be the result of applied educational methods which aim at creating subjectivity and equality of each of the twins before the moment of parting.


Author(s):  
Paterne Micha MBELANGANI MBAN ◽  
Sevtap ÜNAL

The present study aimed to investigate the role of negative feelings on the consumer buying decision. The influence of a brand image, the need for social approval, and negative brand self- expressiveness on brand embarrassment, as well as the influence of embarrassment on brand hate and brand detachment, mediated by interpersonal influence, were investigated. Findings revealed that brand image and the need for social approval do not have any influence on brand embarrassment, while the negative brand self-expressiveness does predict brand embarrassment. On the other side, the findings revealed that brand embarrassment creates brand hate and brand detachment. And, interpersonal influence has a mediating role in the relationship between brand image-brand detachment, negative brand self-expressiveness-brand hate, and negative brand self- expressiveness-brand detachment.


2014 ◽  
Vol 41 (2) ◽  
pp. 241
Author(s):  
Jenita DT Donsu ◽  
M Noor Rochman Hadjam ◽  
Ahmad Husain Asdie ◽  
Rahmat Hidayat

Depression has strong relationship with diabetes mellitus and the aspect of psychology has influence toward the diabetes patient as control. This research aimed to find out the role of psychological factors in dealing with depression suffered by patient of DM-2 and to see the dynamics of both direct and indirect relationship of psychological factors toward the depression of DM-2 patient. The main model is a model that can bring effect of mediation between social support and depression caused by DM-2. Optimism can provide mediating effect of the relationship between social support and self-esteem. Resilience can provide mediating effect of the relationship between social support and self-esteem. Similarly, self-esteem acts as the mediator of the relationship between optimism and resilience toward the depression of DM-2 patient. The result of estimation parameter test showed the direct relationship between social support toward optimism (0.717), resilience (0.811), self-esteem (0.269) and depression (-0.210) and the direct role to depression (-0.397). The higher social support and self-esteem will cause the higher optimism and resilience. On the other hand, the role of self-esteem showed negative coefficient. On the other hand, the role of self-esteem to depression showed a negative coefficient is, the higher self-esteem will be followed by the decrease of depression in patient with DM-2. Keywords: depression, optimism, resilience, self-esteem, social support, DM-2


2021 ◽  
Vol 65 (9) ◽  
pp. 118-129
Author(s):  
Y. Zinin

The overthrow of M. Gaddafi with the assistance of NATO in October 2011 led to the collapse of the vertical of power and institutions of the state and sentenced Libya to a deep systemic crisis. The article examines the peculiarities and role of the tribal factor in the current events in Libya, a country with deeply divided, multi-composite societies (DDS). It is characterized by tribal, regional, racial and ethnoreligious diversity. With 90% of its population having tribal roots, the number of tribes passes 140. This diversity has left its mark on the course of events, affected the struggle for power. The author sums up the shifts that have taken place in the tribal segment of society in recent decades. The rush of members of different tribes to the city led to their fragmentation, diminution of their former structure. The bonds of kinship, the spirit of solidarity, the traditional behaviour of the tribesmen have been to different extents eroded. However, the influence of a tribe or genus that play the role of a bonding society remains essential. This was especially evident after the advent of dual power in 2014, the author assumes. The two poles of domination – Tripoli and Tobruk are trying to play this card to their advantage. On the other hand, the security vacuum caused by the fall of the regime spontaneously filled forces, including regional tribal groups. The scholar tracks how various tribal councils and other entities here and there take on the functions of maintaining resilience and order, ending infighting, returning hostages, etc. In doing so, they often turn to the traditional usual right – Urf. The author agrees with a number of Libyan scholars and other foreign researchers that there are now some signs of a breeding tribal identity in Libya. At the same time, this process is multi–directional, as in Libya, a country with a deeply divided society, tribes can both engage in conflicts and contribute to their peaceful denouement. The researcher draws attention to the fact that the relationship between tribalism and Islamists is rather contradictory. The latter use to argue that “Islam is the solution to all problems.” But their entry into the arena of politics in Libya after October 2011 did not prevent the de facto collapse of the country and the growth of sectarian standoff. And that according to the author divides society and plays into the hands of certain political forces. In this atmosphere, tribal polarization and the general alienation of society are at risk of growth. The author analyzes the relations between tribal and national identities in a country where the process of consolidation of the population into a single nation has not yet been completed.


2017 ◽  
Vol 14 (1) ◽  
pp. 67-81
Author(s):  
Mohd A’Tarahim Mohd Razali Bin Mohd Razali ◽  
Mohd Yakub @ Zulkifli Mohd Yusoff Bin Mohd Yusoff ◽  
Nor Hafizi Yusof Bin Yusof ◽  
Siti Fatimah Salleh Binti Salleh ◽  
Mohd Faiz Hakimi Mat Deris Bin Mat Deris ◽  
...  

The aim of this study is to explore the importance of Qira’at Mutawatirah as a discipline particularly in the field of fiqh (jurisprudence). As a field of study, Qiraat (Quranic reading) plays a significant role in Islamic Fiqh by way of shaping the opinions and views of the fuqaha’ (jurists). Nevertheless, some fuqaha’ are less familiar with Qiraat as a study which has thus led to some confusion and ambiguity on the matter. It was even suggested that the differences of fiqh found within the madzhabs (sects) are based on the fuqaha’s own Qiraat. Thus this paper is a discussion on the differences of wajh Qiraat within the farsh letters as found among the Qiraat scholars. This paper also analyses the relationship and influence of the Qiraat readings among the fuqaha when it comes to deriving a hukm (principle), particularly on fiqh ibadah (the laws of worship). As such, this significant study sheds light into the approach used by the fuqaha’ when it comes to extracting and deriving laws and principles based on the different Qiraat readings. The objectives of this study are to investigate the extent and role of Qiraat, to analyse and observe the relationship between Qiraat readings of the fuqaha and its relationship to the hukm. This study is based entirely on library research. Overall, the findings show that Qiraat is undoubtedly important; the differences in Qiraat have a major impact in the way that the various Islamic Fiqh were derived from the Qur’anic verses. Nevertheless, the chosen Qiraat readings by Fuqaha, on the other hand, do not play a major role in determining the fiqh within the various sects; instead the wajh Qiraat plays a major role within their respective sects. However, in some circumstances, the chosen Qiraat readings do sometimes become a source which a hukm is decided within their sects, and vice versa. It is hoped that this study becomes a pioneer for other researchers to conduct a more in-depth study on the sciences of Qiraat by exploring it critically within the various perspectives of the Islamic discipline. It is hoped that it can be analysed, studied, understood and implemented in the field of teaching and learning, in line with its importance within the other branches of Islamic discipline. It is hoped that as a study, it can be further expanded and remain significant to the Islamic scholars and the community at large. Keyword: Qiraat Mutawatirah, Fiqh, Qiraat, fuqaha‘   Penulisan ini bertujuan merungkai hubungan rapat Qiraat dalam disiplin ilmu Islam terutamanya ilmu Fiqh. Qiraat menjadi salah satu faktor yang dominan terutamanya dalam mencorakkan perbezaan hukum Fiqh Islami dalam kalangan Fuqaha’. Namun masih terdapat kalangan yang kurang mengetahui dan memahami hakikat kewujudan ilmu Qiraat sehingga menimbulkan kekeliruan dan kesamaran mengenainya bahkan wujudnya pendapat menyatakan bahawa hukum fiqh yang diinstibatkan dalam mazhab adalah berdasarkan daripada Qiraat yang dibaca oleh kalangan fuqaha itu sendiri. Justeru kajian ini akan menyentuh dan membincangkan perbezaan wajh qiraat yang terdapat pada farsh huruf dalam kalangan ulama Qiraat. Dalam masa yang sama, kajian ini juga akan menyingkap dan menganalisis perkaitan dan pengaruhnya terhadap pengeluaran hukum oleh kalangan Fuqaha’ terutama ayat-ayat al-Quran yang melibatkan fiqh ibadat. Kajian ini penting demi memahami keadaan sebenar bagaimana kalangan Fuqaha mengeluarkan hukum fiqh berdasarkan perbezaan Qiraat. Objektif kajian ialah mengkaji sejauhmana perkaitan dan peranan Qiraat pada hukum fiqh, menganalisis dan menilai sejauh mana pertalian bacaan Qiraat yang dibaca Fuqaha’ dengan hukum yang diinstibatkan oleh Fuqaha.’ Secara keseluruhannya, kajian ini dijalankan berdasarkan kajian ke perpustakaan sepenuhnya. Ternyata dapatan hasil kajian ini merumuskan bahawa perbezaan Qiraat pula memberi impak yang besar dalam mencorakkan hukum fiqh dalam ayat al-Quran. Bacaan ‘Qiraat PilihanFuqaha‘ pula tidaklah menjadi faktor utama mempengaruhi hukum fiqh mazhab yang diasaskan oleh mereka bahkan fuqaha hanya menjadikan wajh Qiraat itu sebagai platform utama dalam menentukan hukum fiqh dalam mazhab yang diasaskan mereka. Namun tidak dinafikan juga, bacaan ‘Qiraat Pilihan Fuqaha‘ itu kekadang menjadi sebab penentuan hukum bagi mazhab mereka dan kekadangnya sebaliknya. Kajian ini diharap menjadi perintis kepada pengkaji yang lain untuk lebih prolifik mengenai ilmu Qiraat dalam membahaskannya dari pelbagai sudut disiplin ilmu Islam secara lebih kritis supaya ia dapat ditelaah, dikaji, difahami, diperkasai dan diimplimentasikan dalam aspek pengajaran dan pembelajaran sejajar dengan kepentingannya terhadap cabangan ilmu-ilmu Islam yang lain agar terus berkembang dan bertapak pada kaca mata Ilmuan Islam secara khusus dan masyarakat sejagat secara umumnya.   Kata Kunci: Qiraat Mutawatirah, Fiqh, Qiraat, fuqaha‘.


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