scholarly journals Challenges, consequences, and lessons for way–outs to emergencies at hospitals: a systematic review study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Hamid Reza Rasouli ◽  
Ali Aliakbar Esfahani ◽  
Mohsen Abbasi Farajzadeh

Abstract Background Emergency Department (ED) overcrowding adversely affects patients’ health, accessibility, and quality of healthcare systems for communities. Several studies have addressed this issue. This study aimed to conduct a systematic review study concerning challenges, lessons and way outs of clinical emergencies at hospitals. Methods Original research articles on crowding of emergencies at hospitals published from 1st January 2007, and 1st August 2018 were utilized. Relevant studies from the PubMed and EMBASE databases were assessed using suitable keywords. Two reviewers independently screened the titles, abstracts and the methodological validity of the records using data extraction format before their inclusion in the final review. Discussions with the senior faculty member were used to resolve any disagreements among the reviewers during the assessment phase. Results Out of the total 117 articles in the final record, we excluded 11 of them because of poor quality. Thus, this systematic review synthesized the reports of 106 original articles. Overall 14, 55 and 29 of the reviewed refer to causes, effects, and solutions of ED crowding, respectively. The review also included four articles on both causes and effects and another four on causes and solutions. Multiple individual patients and healthcare system related challenges, experiences and responses to crowding and its consequences are comprehensively synthesized. Conclusion ED overcrowding is a multi-facet issue which affects by patient-related factors and emergency service delivery. Crowding of the EDs adversely affected individual patients, healthcare delivery systems and communities. The identified issues concern organizational managers, leadership, and operational level actions to reduce crowding and improve emergency healthcare outcomes efficiently.

2015 ◽  
Vol 14 (4) ◽  
pp. 411-432 ◽  
Author(s):  
Leigh Murray ◽  
Phyllis N. Butow

AbstractObjective:Motor neuron disease (MND) is an incurable progressive illness, characterized by incessant deterioration of neuromuscular function. Timely commencement of advance care planning (ACP) may enable patients to participate in future care choices. The present systematic review aimed to summarize what is known about the prevalence, content, patient/caregiver benefits, healthcare professional (HCP) awareness/support, and healthcare outcomes associated with ACP in the MND setting.Method:Quantitative and qualitative studies were identified through database searches and eligibility assessed by one author and verified by her coauthor. Data extraction and quality assessments against standardized criteria were completed by the two authors.Results:Of the 422 studies identified, 16 were included. The research methods generally lacked rigor. Advance directive (AD) prevalence varied considerably across studies. Disease progression was the strongest predictor of AD completion. ACP processes may clarify patients' wishes and promote communication. HCP attitudes or lack of awareness may limit ACP processes. Varying patient preferences may make flexible approaches and timing necessary.Significance of results:Important benefits may be associated with ACP in the context of a motor neuron disease (e.g., feelings of control/relief and refusal of unwanted treatments). However, further evidence is required to verify findings and identify optimal streamlined approaches (e.g., use of decision aids) consistent with patients' (and caregivers') needs over time.


2021 ◽  
Author(s):  
Jack Birch ◽  
Rebecca Jones ◽  
Julia Mueller ◽  
Matthew McDonald ◽  
Rebecca Richards ◽  
...  

Background: It has been suggested that interventions focusing on individual behaviour change, such as behavioural weight management interventions, may exacerbate health inequalities. These intervention-generated inequalities may occur at different stages, including intervention uptake, adherence and effectiveness. We conducted a systematic review to synthesise evidence on how different measures of inequality moderate the uptake of, adherence to and effectiveness of behavioural weight management interventions in adults. Methods: We updated a previous systematic literature review from the US Preventive Services Taskforce to identify trials of behavioural weight management interventions in adults that could be conducted in or recruited from primary care. Medline, Cochrane database (CENTRAL) and PsycINFO were searched. Only randomised controlled trials and cluster-randomised controlled trials were included. Two investigators independently screened articles for eligibility and conducted risk of bias assessment. We curated publication families for eligible trials. The PROGRESS-Plus acronym (place of residence, race/ethnicity, occupation, gender, religion, education, socioeconomic status, social capital, plus other discriminating factors) was used to consider a comprehensive range of health inequalities. Data on trial uptake, intervention adherence, weight change, and PROGRESS-Plus related-data were extracted. Results: Data extraction in currently underway. A total of 108 studies are included in the review. Data will be synthesised narratively and through the use of Harvest Plots. A Harvest plot for each PROGRESS-Plus criterion will be presented, showing whether each trial found a negative, positive or no health inequality gradient. We will also identify potential sources of unpublished original research data on these factors which can be synthesised through a future individual participant data meta- analysis. Conclusions and implications: The review findings will contribute towards the consideration of intervention-generated inequalities by researchers, policy makers and healthcare and public health practitioners. Authors of trials included in the completed systematic review may be invited to collaborate on a future IPD meta-analysis. PROSPERO registration number: CRD42020173242


2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Gabrielle Chicoine ◽  
José Côté ◽  
Jacinthe Pepin ◽  
Guillaume Fontaine ◽  
Marc-André Maheu-Cadotte ◽  
...  

Abstract Background The Extension for Community Healthcare Outcomes (ECHO) Model of continuing tele-education is an innovative guided-practice model aiming at amplifying healthcare professionals’ competencies in the management of chronic and complex health conditions. While data on the impact of the ECHO model is increasingly available in the literature, what influences the model effectiveness remains unclear. Therefore, the overarching aim of this systematic review is to identify, appraise, and synthesize the available quantitative (QUAN) and qualitative (QUAL) evidence regarding the ECHO Model effectiveness and the experiences/views of ECHO’s participants about what influences the development of competencies in healthcare professionals. Methods The proposed systematic review was inspired by the Joanna Briggs Institute (JBI) methodology for Mixed Methods Systematic Reviews (MMSR) and will follow a convergent segregated approach. A systematic search will be undertaken using QUAN, QUAL and mixed methods (MM) studies of ECHO-affiliated programs identified in six databases. A publication date filter will be applied to find the articles published from 2003 onwards. Sources of unpublished studies and gray literature will be searched as well. Retrieved citations will independently be screened by two reviewers. Disagreements will be resolved through discussion until a consensus is reached or by including a third reviewer. Studies meeting the predefined inclusion criteria will be assessed on methodological quality and the data will be extracted using standardized data extraction forms. Separate QUAN and QUAL synthesis will be performed, and findings will be integrated using a matrix approach for the purpose of comparison and complementarity. Discussion This MMSR will fulfill important gaps in the current literature on the ECHO Model as the first to provide estimates on its effectiveness and consider simultaneously the experiences/views of ECHO’s participants. As each replication of the ECHO Model greatly varies depending on the context, topic, and targeted professionals, a better understanding of what influences the model effectiveness in developing healthcare professionals’ competencies is crucial to inform future implementation. Systematic review registration PROSPERO CRD42020197579


2021 ◽  
Author(s):  
Meimei Wang ◽  
Fengqin Li ◽  
Jing Zhang ◽  
Cheng Lu ◽  
Yan Meng ◽  
...  

Abstract Background Gaucher disease, an autosomal recessive lysosomal storage disorder, is characterized by progressive lysosomal storage of glucocerebroside in macrophages predominantly in bone, bone marrow, liver, and spleen. Meta-analysis of global Gaucher disease epidemiology was not available prior to this study. Methods To provide a systematic review and meta-analysis of birth prevalence and prevalence of Gaucher disease in multiple countries. MEDLINE and EMBASE databases were searched for original research articles on the epidemiology of Gaucher disease from inception until July 21, 2021. Meta-analysis, adopting a random effects logistic model, was performed to estimate birth prevalence and prevalence of Gaucher disease. Results Eighteen studies that were screened out of 1874 records were included for data extraction. The studies that fulfilled the criteria for inclusion involved 15 areas/countries. The global birth prevalence of Gaucher disease was 1.5 cases (95% CI: 1.0-2.0) per 100,000 live births. The global prevalence of Gaucher disease was 0.9 cases (95% CI: 0.7-1.1) per 100,000 inhabitants. Conclusions To our knowledge, this is the first comprehensive systematic review that presented quantitative data by evaluating global epidemiology of Gaucher disease. Quantitative data of global epidemiology of Gaucher disease could be the fundamental to evaluate the global efforts that improve many factors, including diagnostic technology and data collection, which affect global epidemiology of Gaucher disease.


2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Tess M. E. Derksen ◽  
Martijn J. L. Bours ◽  
Floortje Mols ◽  
Matty P. Weijenberg

Background.Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect of chemotherapy treatment in colorectal cancer (CRC), negatively affecting the daily functioning and quality of life of CRC patients. Currently, there are no established treatments to prevent or reduce CIPN. The purpose of this systematic review was to identify lifestyle-related factors that can aid in preventing or reducing CIPN, as such factors may promote self-management options for CRC patients suffering from CIPN.Methods.A literature search was conducted through PubMed, Embase, and Google Scholar. Original research articles investigating oxaliplatin-related CIPN in CRC were eligible for inclusion.Results.In total, 22 articles were included, which suggested that dietary supplements, such as antioxidants and herbal extracts, as well as physical exercise and complementary therapies, such as acupuncture, may have beneficial effects on preventing or reducing CIPN symptoms. However, many of the reviewed articles presented various limitations, including small sample sizes and heterogeneity in study design and measurements of CIPN.Conclusions.No strong conclusions can be drawn regarding the role of lifestyle-related factors in the management of CIPN in CRC patients. Certain dietary supplements and physical exercise may be beneficial for the management of CIPN, but further research is warranted.


Author(s):  
Onur Dogan ◽  
Sanju Tiwari ◽  
M. A. Jabbar ◽  
Shankru Guggari

AbstractA pandemic disease, COVID-19, has caused trouble worldwide by infecting millions of people. The studies that apply artificial intelligence (AI) and machine learning (ML) methods for various purposes against the COVID-19 outbreak have increased because of their significant advantages. Although AI/ML applications provide satisfactory solutions to COVID-19 disease, these solutions can have a wide diversity. This increase in the number of AI/ML studies and diversity in solutions can confuse deciding which AI/ML technique is suitable for which COVID-19 purposes. Because there is no comprehensive review study, this study systematically analyzes and summarizes related studies. A research methodology has been proposed to conduct the systematic literature review for framing the research questions, searching criteria and relevant data extraction. Finally, 264 studies were taken into account after following inclusion and exclusion criteria. This research can be regarded as a key element for epidemic and transmission prediction, diagnosis and detection, and drug/vaccine development. Six research questions are explored with 50 AI/ML approaches in COVID-19, 8 AI/ML methods for patient outcome prediction, 14 AI/ML techniques in disease predictions, along with five AI/ML methods for risk assessment of COVID-19. It also covers AI/ML method in drug development, vaccines for COVID-19, models in COVID-19, datasets and their usage and dataset applications with AI/ML.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Marilyn Aita ◽  
Gwenaëlle De Clifford Faugère ◽  
Andréane Lavallée ◽  
Nancy Feeley ◽  
Robyn Stremler ◽  
...  

Abstract Background As preterm infants’ neurodevelopment is shaped by NICU-related factors during their hospitalization, it is essential to evaluate which interventions are more beneficial for their neurodevelopment at this specific time. The objective of this systematic review and meta-analysis was to evaluate the effectiveness of interventions initiated during NICU hospitalization on preterm infants’ early neurodevelopment during their hospitalization and up to two weeks corrected age (CA). Methods This systematic review referred to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses [PRISMA] guidelines and was registered in PROSPERO (CRD42017047072). We searched CINAHL, MEDLINE, PubMed, EMBASE (OVID), Cochrane Systematic Reviews, CENTRAL, and Web of Science from 2002 to February 2020 and included randomized controlled/clinical trials conducted with preterm infants born between 24 and 366/7 weeks of gestation. All types of interventions instigated during NICU hospitalization were included. Two independent reviewers performed the study selection, data extraction, assessment of risks of bias and quality of evidence. Results Findings of 12 studies involving 901 preterm infants were synthesized. We combined three studies in a meta-analysis showing that compared to standard care, the NIDCAP intervention is effective in improving preterm infants’ neurobehavioral and neurological development at two weeks CA. We also combined two other studies in a meta-analysis indicating that parental participation did not significantly improve preterm infants’ neurobehavioral development during NICU hospitalization. For all other interventions (i.e., developmental care, sensory stimulation, music and physical therapy), the synthesis of results shows that compared to standard care or other types of comparators, the effectiveness was either controversial or partially effective. Conclusions The overall quality of evidence was rated low to very low. Future studies are needed to identify interventions that are the most effective in promoting preterm infants’ early neurodevelopment during NICU hospitalization or close to term age. Interventions should be appropriately designed to allow comparison with previous studies and a combination of different instruments could provide a more global assessment of preterm infants’ neurodevelopment and thus allow for comparisons across studies. Trial registration Prospero CRD42017047072.


2021 ◽  
Author(s):  
Anthony Duffy ◽  
Greg Christie ◽  
Sylvain Moreno

BACKGROUND Digital Health Interventions (DHIs) are rapidly evolving the landscape of healthcare. Multiple studies have shown their propensity to extend both the quality and reach of interventions. However, failure to improve DHI development is linked to failed uptake and health outcomes. This dilemma is further conflicted by the colliding backdrops of the digital and health industries respectively, which approach, understand and involve end users differently in the framing of a DHI. OBJECTIVE The objective of this systematic review is to assess the challenges to incorporate end users in the development of digital health interventions, to identify emerging hybridised solutions, and to identify limitations and gaps for areas of future investigation. METHODS The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA-P) will be used to structure this protocol. A systematic search of the PsycInfo, PubMed (Medline), Web of Science, CINAHL and IEEE Xplore databases will be conducted. Additionally, the PerSPEcTiF guidelines for complex interventions will be consulted. Two reviewers will independently screen the titles and abstracts of the identified references and select studies according to the eligibility criteria. Any discrepancies will then be discussed and resolved. Two reviewers will independently extract and validate data from the included studies into a standardised form and conduct quality appraisal. RESULTS As of February 2020, we have completed a preliminary literature search examining challenges to incorporate end users in the development of DHI. Systematic searches, data extraction and analysis, and writing of the systematic review are expected to be completed by August 2021. CONCLUSIONS This systematic review aims to provide an effective summary of challenges to incorporate end users in the development of DHIs. Results from this review will provide an evidence base for a more harmonised approach to end users that satisfies the needs of healthcare outcomes and digital design and development respectively.


2020 ◽  
Author(s):  
Marilyn Aita ◽  
Gwenaëlle De Clifford-Faugère ◽  
Andréane Lavallée ◽  
Nancy Feeley ◽  
Robyn Stremler ◽  
...  

Abstract Background : As preterm infants’ neurodevelopment is shaped by NICU-related factors during their hospitalization, it is essential to evaluate which interventions are more beneficial for their neurodevelopment at this specific time. The primary objective of this systematic review and meta-analysis was to evaluate the effectiveness of interventions initiated during NICU hospitalization on preterm infants’ early neurodevelopment during their hospitalization and up to two weeks corrected age (CA). Methods: This systematic review referred to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses [PRISMA] guidelines and was registered in PROSPERO (CRD42017047072). We searched CINAHL, MEDLINE, PubMed, EMBASE (OVID), Cochrane Systematic Reviews, CENTRAL, and Web of Science from 2002 to February 2020. Two independent reviewers performed the study selection, data extraction, assessment of risks of bias and quality of evidence. Results: Findings of 12 studies involving 901 preterm infants were synthesized. We combined three studies in a meta-analysis showing that compared to standard care, NIDCAP intervention is effective in improving preterm infants’ neurobehavioral and neurological development at two weeks CA. We also combined two other studies in a meta-analysis indicating that parental participation did not significantly improve preterm infants’ neurobehavioral development during NICU hospitalization. For all other interventions (i.e., developmental care, sensory stimulation, music and physical therapy), the synthesis of results shows that compared to standard care or other types of comparators, the effectiveness was either controversial or partially effective. Conclusions: The overall quality of evidence was rated low to very low. Future studies are needed to identify interventions that are the most effective in promoting preterm infants’ neurodevelopment during NICU hospitalization or close to term age. Interventions should be appropriately designed to allow comparison with previous studies and a combination of different instruments could provide a more global assessment of preterm infants’ neurodevelopment and thus allow for comparisons across studies. Systematic Review Protocol Registration: Prospero CRD42017047072


Author(s):  
Khairil Idham Ismail ◽  
Hanizah Mohd Yusof ◽  
Ahmad Faidhi MZ ◽  
Basri I

Introduction: Fatigue is common among healthcare workers (HCWs). Long continuous duty hours, sleep loss with minimal recuperation and shift work are among work-related factors contributing to fatigue. Being fatigued will impair physical, cognitive, and emotional function. Substantially, it will impact the occupational and patient safety along with quality of healthcare delivery. Nevertheless, there are still paucity of Islamic perspective on the importance of fatigue management for HCWs.Objectives: Our aim is to outline the Islamic perspective of fatigue management for HCWs.Methods: Review of literature in relevance to fatigue among HCWs were carried out. Document analysis from Islamic jurisprudence (fiqh) references including literature from Maqasid Syariah (the Objective of Syariah) and Qawaid Fiqhiyyah (Islamic legal maxims) perspective. Interviews with expert from both Islamic scholars and clinicians are conducted.Results: Our findings provide Islamic perspective on the importance of fatigue manageme nt for healthcare workers. The consequences of fatigue such as slowed reaction time, reduced vigilance, reduced decision-making ability, poor judgment, distraction during complex task and loss of awareness in critical situations raise the issue on the integrity of patient safety and occupational safety. This is in contrary with the principle of Maqasid Syariah which highly emphasize protection of life (hifz an-Nafs) and intellect (hifz ‘Aql) of both group of HCWs and patients. While Qawaid Fiqhiyyah strongly against inflicting harm to themselves nor bring harm to others (La darar wa la dirar); which serve as basis to support this fatigue manageme nt framework in a holistic manner.Conclusion: This study may serve as an added perspective in the angle of Islamic view on the importance of fatigue management for healthcare workers.International Journal of Human and Health Sciences Supplementary Issue: 2019 Page: 37


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