scholarly journals COVID-19 in Northeast Bosnia and Herzegovina and patient’s length of hospitalization

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Alma Trnacevic ◽  
Amer Mujkanovic ◽  
Noura Al-Salloum ◽  
Amra Sakusic ◽  
Emir Trnacevic ◽  
...  

Abstract Background Since the outbreak of COVID-19 pandemic, clinical data from various parts of the world have been reported. Up till now, there has been no clinical data with regards to COVID-19 from Bosnia and Herzegovina (B&H). The aim was to report on the first cohort of patients from B&H and to analyze factors that influence COVID-19 patient’s length of hospitalization (LOH). Methods This retrospective cohort study was conducted at Tuzla University Clinical Center (UKC), B&H. It involved 25 COVID-19 positive patients that needed hospitalisation between March 28th and April 27th 2020. The LOH was measured from the time of admission to discharge. Factors analyzed induced age, BMI, presence of known comorbidities, serum creatinine and O2 saturation upon admission. Results The mean age was 52.92 ± 19.15 years and BMI 28.80 ± 4.22. LOH for patients with BMI < 25 was 9 ± SE2.646 days (CI 95% 3.814–14.816) vs 14.182 ± SE .937 (CI 95% 12.346–16.018 p < 0.05; HR 5.148 CI95% 1.217 to 21.772 p = 0.026) for ≥25 BMI. The mean LOH of patients with normal levels of O2 ≥ 95% was 11.667 ± SE1.202 (CI95% 8.261 to 13.739; p = 0.046), while LOH for patients with < 95% was 14.625 ± SE 1.231 CI95% 12.184 to 16.757 p = 0.042; HR 3.732 CI95%1.137–12.251 p = 0.03). Patients without known comorbidities had a mean LOH of 11.700 ± SE1.075 (CI 95% 9.592–13.808), while those with comorbidities had a mean of 14.8 ± 1.303 (CI 95% 12.247–17.353; p = 0.029) with HR2.552. Conclusion LOH varied among COVID-19 patients and was prolonged when analyzed for BMI ≥25, comorbidities, elevated creatinine, and O2 saturation < 95%. Furthermore, risk factors for COVID-19 patients in B&H do not deviate from those reported in other countries.

2020 ◽  
Author(s):  
Alma Trnacevic ◽  
Amer Mujkanovic ◽  
Noura Al-Salloum ◽  
Amra Sakusic ◽  
Emir Trnacevic ◽  
...  

Abstract Background Since the outbreak of COVID-19 pandemic, clinical data from various parts of the world have been reported. Until now, there has been no clinical data with regards to COVID-19 from Bosnia and Herzegovina (B&H). The aim was to report on the first cohort of patients from B&H and to analyze clinical factors of COVID-19 patients that have influenced the length of hospitalization (LOH) of COVID-19 infected patients.Methods This retrospective cohort study was conducted at Tuzla University Clinical Center (UKC). It included 25 COVID-19 positive patients that were hospitalized between March 28th and April 27th 2020. The LOH was measured from the time of admission to discharge. Factors analyzed induced age, BMI, presence of known comorbidities, serum creatinine and O2 saturation upon admission.Results The mean age was 52.92±19.15 years and BMI 28.80±4.22. LOH for patients with BMI <25 was 9± SE2.646 days (CI 95% 3.814-14.816) vs 14.182 ±SE .937 (CI 95% 12.346-16.018 p<0.05; HR 5.148 CI95% 1.217 to 21.772 p=0.026) for ≥25 BMI. The mean LOH of patients with normal levels of O2 ≥95% was 11.667 ±SE1.202 (CI95% 8.261 to 13.739; p=0.046), while LOH for patients with <95% was 14.625 ±SE 1.231 CI95% 12.184 to 16.757 p=0.042; HR 3.732 CI95%1.137-12.251 p=0.03). Patients without known comorbidities had a mean LOH of 11.700± SE1.075 (CI 95% 9.592-13.808), while those with comorbidities had a mean of 14.8±1.303 (CI 95% 12.247-17.353; p=0.029) with HR2.552Conclusion LOH varied among COVID-19 patients and was prolonged when clinical characteristics such as BMI, known comorbidities, elevated creatinine, and O2 saturation <95% were present. Furthermore, risk factors for COVID-19 patients in B&H do not deviate from those reported in other countries.


2020 ◽  
Author(s):  
Alma Trnacevic ◽  
Amer Mujkanovic ◽  
Noura Al-Salloum ◽  
Amra Sakusic ◽  
Emir Trnacevic ◽  
...  

Abstract Background Since the outbreak of COVID-19 pandemic clinical data from various parts of the world have been reported; until now, there has been no clinical data with regards to COVID-19 from Bosnia and Herzegovina (B&H). The aim was to report on the first cohort of patients from B&H and to analyze clinical factors of COVID-19 patients that may influence the length of hospitalization (LOH) of COVID-19 infected patients.Methods Retrospective cohort study was conducted at Tuzla University Clinical Center (UKC). It included 25 COVID-19 positive patients that were hospitalized between March 28th and April 27th 2020. The LOH was measured from the time of admission to discharge. Factors analyzed induced age, BMI, presence of comorbidities, serum creatinine and oxygen saturation upon admission.Results The mean age was 52.92±19.15 years and BMI 28.80±4.22. LOH for patients with normal BMI was 9±SE2.646 days (CI 95% 3.814-14.816) vs 14.182 ±SE .937 (CI 95% 12.346-16.018; p<0.05) for ≥25 BMI. Patients without underlying diseases had a LOH of 11.70 ±SE1.075 (CI 95% 9.592-13.808), while those with comorbidities 14.8 ±SE1.303 (CI95% 12.247-17.353; p<0.05). Conclusion LOH varied among COVID-19 patients and was prolonged when clinical characteristics such as elevated BMI, presence of comorbidities, elevated creatinine and low oxygen saturation levels were taken into consideration. Furthermore, risk factors for COVID-19 patients in B&H do not deviate from data reported in other countries.


2020 ◽  
Author(s):  
Alma Trnacevic ◽  
Amer Mujkanovic ◽  
Noura Al-Salloum ◽  
Amra Sakusic ◽  
Emir Trnacevic ◽  
...  

Abstract Background Since outbreak of COVID-19 pandemic clinical data from various parts of the world have been reported, until now there has been no provide data from Bosnia and Herzegovina (B&H) about COVID-19. Aim was to report on the first cohort of patients from B&H and to analyze clinical factors of COVID-19 patients that influence the length of hospitalization. Methods Retrospective cohort study conducted at UKC Tuzla. The study included 25 COVID-19 positive patients that were hospitalized between March 28th and April 27th 2020. The LOH was measured from the time of admission to discharge. Hospitalization greater than 10 days was considered as prolonged. Factors analyzed induced age, BMI, comorbidities, serum creatinine and oxygen saturation upon admission.Results The mean age was 52.92±19.15 years and BMI 28.80±4.22. LOH for patients with normal BMI was 9±SE2.646 days (CI 95% 3.814-14.816) vs 14.182 ±SE .937 (CI 95% 12.346-16.018; p<0.05) for ≥25 BMI. Patients without underlying diseases had a LOH of 11.70 ±SE1.075 (CI 95% 9.592-13.808), while those with comorbidities 14.8 ±SE1.303 (CI95% 12.247-17.353; p<0.05). Conclusion LOH varied among COVID-19 patients and was prolonged when clinical characteristics such as elevated BMI, comorbidities, elevated creatinine and low oxygen saturation levels were taken into consideration. Furthermore, risk factors for COVID-19 patients in B&H do not deviate from data reported in other countries.


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 224
Author(s):  
Cristian Díaz-Vélez ◽  
Diego Urrunaga-Pastor ◽  
Anthony Romero-Cerdán ◽  
Eric Ricardo Peña-Sánchez ◽  
Jorge Luis Fernández Mogollon ◽  
...  

Background: Peru was one of the countries with the highest COVID-19 mortality worldwide during the first stage of the pandemic. It is then relevant to evaluate the risk factors for mortality in patients hospitalized for COVID-19 in three hospitals in Peru in 2020, from March to May, 2020.  Methods: We carried out a retrospective cohort study. The population consisted of patients from three Peruvian hospitals hospitalized for a diagnosis of COVID-19 during the March-May 2020 period. Independent sociodemographic variables, medical history, symptoms, vital functions, laboratory parameters and medical treatment were evaluated. In-hospital mortality was assessed as the outcome. We performed Cox regression models (crude and adjusted) to evaluate risk factors for in-hospital mortality. Hazard ratios (HR) with their respective 95% confidence intervals (95% CI) were calculated.  Results: We analyzed 493 hospitalized adults; 72.8% (n=359) were male and the mean age was 63.3 ± 14.4 years. COVID-19 symptoms appeared on average 7.9 ± 4.0 days before admission to the hospital, and the mean oxygen saturation on admission was 82.6 ± 13.8. While 67.6% (n=333) required intensive care unit admission, only 3.3% (n=16) were admitted to this unit, and 60.2% (n=297) of the sample died. In the adjusted regression analysis, it was found that being 60 years old or older (HR=1.57; 95% CI: 1.14-2.15), having two or more comorbidities (HR=1.53; 95% CI: 1.10-2.14), oxygen saturation between 85-80% (HR=2.52; 95% CI: 1.58-4.02), less than 80% (HR=4.59; 95% CI: 3.01-7.00), and being in the middle (HR=1.65; 95% CI: 1.15-2.39) and higher tertile (HR=2.18; 95% CI: 1.51-3.15) of the neutrophil-to-lymphocyte ratio, increased the risk of mortality.  Conclusions: The risk factors found agree with what has been described in the literature and allow the identification of vulnerable groups in whom monitoring and early identification of symptoms should be prioritized in order to reduce mortality.


2010 ◽  
Vol 43 (4) ◽  
pp. 452-454 ◽  
Author(s):  
Felipe Francisco Tuon ◽  
Leila Carolina Bianchet ◽  
Sergio Ricardo Penteado-Filho

INTRODUCTION: Enterobacter can be included in the group of extended spectrum β-lactamases (EBSL)-producing bacteria, though few studies exist evaluating risk factors associated with this microorganism. A retrospective cohort study was conducted to determine risk factors associated with ESBL-producing-Enterobacter and mortality METHODS: A retrospective cohort study with 58 bacteremia caused by ESBL-producing-Enterobacter (28 cases) and non-ESBL (30 cases) RESULTS: Risk factors associated with ESBL-Enterobacter were trauma, length of hospitalization, admission to the intensive care unit, urinary catheter and elective surgery (p< 0.05). The survival curves were similar for ESBL and non-ESBL CONCLUSIONS: ESBL-producing-Enterobacter bacteremia is prevalent and the survival curve was similar to non-ESBL-producing strains.


2011 ◽  
Vol 25 (4) ◽  
pp. 215-219 ◽  
Author(s):  
Dana C Moffatt ◽  
Pradermchai Kongkam ◽  
Haritha Avula ◽  
Stuart Sherman ◽  
Evan L Fogel ◽  
...  

BACKGROUND: Placement of prophylactic pancreatic stents (PPS) is a method proven to reduce the rate and severity of postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in high-risk patients; however, PPS do not eliminate the risk completely. Early PPS dislodgement may occur prematurely and contribute to more frequent or severe PEP.OBJECTIVE: To determine the effect of early dislodgement of PPS in patients with moderate or severe PEP.METHOD: A total of 27,176 ERCP procedures from January 1994 to September 2007 for PPS placement in high-risk patients were analyzed. Patient and procedure data were analyzed to assess risk factors for PEP, and to evaluate the severity of pancreatitis, length of hospitalization and subsequent complications. Timing of stent dislodgment was assessed radiographically.RESULTS: PPS were placed in 7661 patients. Of these, 580 patients (7.5%) developed PEP, which was graded as mild in 460 (6.0%), moderate in 87 (1.1%) and severe in 33 (0.4%). Risk factors for developing PEP were not different in patients who developed moderate PEP compared with those with severe PEP. PPS dislodged before 72 h in seven of 59 (11.9%) patients with moderate PEP and five of 27 (18.5%) patients with severe PEP (P=0.505). The mean (± SD) length of hospitalization in patients with moderate PEP with stent dislodgement before and after 72 h were 7.43±1.46 days and 8.37±1.16 days, respectively (P=0.20). The mean length of hospitalization in patients with severe PEP whose stent dislodged before and after 72 h were 21.6±6.11 and 22.23±3.13 days, respectively (P=0.96).CONCLUSION: Early PPS dislodgement was associated with moderate and severe PEP in less than 20% of cases and was not associated with a more severe course. Factors other than ductal obstruction contribute to PEP in high-risk patients undergoing ERCP and PPS placement.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S579-S580
Author(s):  
Harry Cheung ◽  
Marwan M Azar ◽  
Geliang Gan ◽  
Yanhong Deng ◽  
Elizabeth A Cohen ◽  
...  

Abstract Background Opportunistic infections (OIs) in kidney transplant recipients (KTR) most commonly occur in the early post-transplant period or with increased immunosuppression, largely as a result of impaired T-cell function. Additionally, age confers susceptibility to infection independent of time post-transplant. The combined impact of cumulative immunosuppression and immunosenescence on infection risk of long-term KT survivors has not been well described. Methods We performed a retrospective chart review of patients age ≥ 18 years who underwent KT between 2003 to 2009 and who survived ≥ 10 years post-KT, in order to evaluate the risk factors for OIs. Demographics, comorbidities, immunosuppression, and clinical data for OIs occurring ≥ 10 years of KT were collected. AST ID Working Group on Infectious Disease Monitoring definitions for OIs was used. Risk factors for OIs were assessed by simple logistic regression. Results Of 332 KTR, 16 (4.8%) had an OI with 18 total episodes. Of 16 KTR, half were white, 10 (62.5%) were male, median age at time of transplant was 43 (range 25-72) and the median post-transplant follow-up was 14.2 years (range 10.3-37.6). The mean Charlson Comorbidity Index (CCI) at diagnosis was 5.6 (S.D. 3.6). Ten patients (62.5%) were on mycophenolate-based regimens. The mean absolute lymphocyte count (ALC) at the time of OI was 0.78 x 103/µL (S.D. 0.43). Two (12.5%) had acute rejection within 1 year of OI. Of 18 OI episodes, there were 6 PJP, 2 candida esophagitis, 3 CMV (2 viremia, 1 colitis), 2 cryptococcal infections (1 meningitis, 1 myositis/disseminated), 2 adenovirus (pneumonia, colitis), 2 VZV (herpes zoster) and 1 HSV (esophagitis). Two patients had 2 concurrent OIs (1 had PJP and cryptococcus and 1 had HSV and candida esophagitis). Three died within 30-days of OI diagnosis. OI incidence was associated with years from date of transplant [OR 1.3, p=0.002], cerebrovascular disease [OR 4.45, p=0.02], and lower ALC [OR 5.9, p &lt; 0.05]. CCI also trended towards association [OR 1.24, p=0.09]. Table 1: Demographics, comorbidities, immunosuppression, and clinical data for patients with OIs Table 2: Detailed characteristics of each patient with opportunistic infections Conclusion OIs were infrequently observed beyond 10 years of transplant among long-term survivors of KT. However, OI incidence was associated with poor outcome. Low ALC and a higher burden of comorbidities were risk factors for very late occurrence of OIs in this population. Disclosures All Authors: No reported disclosures


Author(s):  
Sanja Bajgorić ◽  
Muris Đug

The research was conducted in order to determine the differences in situational-motor abilities in the defense of men's junior national teams at the 2013 World Handball Championship. Situational - motor abilities in the defense of the national team of Bosnia and Herzegovina in relation to the national teams of Croatia, France, Sweden and Spain were analyzed. The following variables were used to determine differences in defense: SKODEKUK / PR - total - average number of jumps in defense of the whole team, SKODUK / PR1 - total - average number of jumps in defense first player of defense, SKODUK / PR2 - total - average number of jumps in defense second defensive player, SKODUK / PR3 - total - average number of defensive jumps third defensive player, SKODUK / PR4 - total - average number of defensive jumps fourth defensive player, SKODUK / PR5 - total - average number of defensive jumps fifth defensive player and SKODUK / PR6 - total - average number of jumps in the sixth defense player. To determine the partial quantitative differences of variables, which measure the total and average number of attempts to perform an element in the area of situational - motor abilities in defense, we used the mean difference of mean (hereinafter MD), which calculated the average values of selected variables. The average values of variables for the assessment of situational - motor abilities in defense were also calculated. The variable SKODUK / PR4 - total - average number of jumps in the defense of the fourth player shows a statistically significant negative difference in the jumps in the defense of the fourth player between the fourth player in the defense of Bosnia and Herzegovina and the fourth player in the defense of Croatia and Sweden. In the variable SKODUK / PR6 - total - average number of jumps in the defense of the sixth defense player, a statistically significant negative difference can be seen between the sixth player in the defense of the national team of Bosnia and Herzegovina and the sixth player in the defense of Sweden. Key words: handball, juniors, World Championship, defense, situational - motor abilities


2014 ◽  
Vol 60 (5) ◽  
pp. 479-483 ◽  
Author(s):  
Sônia M.H.A. Araújo ◽  
Maria Zenaide D. Ribeiro ◽  
Rafael S. A. Lima ◽  
Geraldo B. Silva Junior ◽  
Camilla N. Jacinto ◽  
...  

Objective: chronic kidney disease (CKD) is an increasing common problem in the world due to the exponential growth of diabetes mellitus, hypertension and other risk factors. The aim of this study is to investigate urinary abnormalities and risk factors for kidney disease in the general population. Methods: this study was performed from data collected during the annual World Kidney Day (WKD) campaigns, in Fortaleza, Ceará, Brazil, between 2009 and 2012. The population sought assistance spontaneously in stands placed in high people-traffic areas. Results: among 2,637 individuals interviewed, the mean age was 50.7±15.7 years and 53% were male. The main risk factors found were sedentarism (60.7%), obesity (22.7%) and smoking (19.8%). Blood pressure (BP) > 140x90 mmHg was found in 877 (33%). Increased BP was found for the first time in 527 cases (19.9%). Cardiovascular diseases were reported in 228 (8.6%). Diabetes was related by 343 (13%). Capillary blood glucose > 200 mg/dL was found in 127 (4.8%) and it was > 200 mg/dL for the first time in 30 (1.13%). Urinalysis was performed in 1,151 people and found proteinuria in 269 (23.3%). Proteinuria was most frequent in hypertension people (77.3% vs. 55.8%, p=0.0001), diabetes mellitus (22.7% vs. 15.2%, p=0.005) and elderly (42.1% vs. 30.7%, p=0.0007). Conclusion: risk factors for CKD are frequent in the general population. Many individuals had hypertension and diabetes and did not know this. It is important to regularly perform actions like WKD in order to early detect potential candidates for CKD.


2011 ◽  
Vol 28 (11) ◽  
pp. 1314-1317 ◽  
Author(s):  
Irma Casas ◽  
Nieves Sopena ◽  
Maria Esteve ◽  
Maria Dolores Quesada ◽  
Isabel Andrés ◽  
...  

To determine the prevalence of and risk factors for methicillin-resistantStaphylococcus aureus(MRSA) carriage at the time of admission to our hospital, we screened the medical records of 1,128 patients for demographic and clinical data. The antimicrobial resistance pattern and genotype of MRSA isolates were studied. The prevalence of MRSA carriage at hospital admission was 1.4%. Older patients and patients previously admitted to healthcare centers were the most likely to have MRSA carriage at admission.


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