scholarly journals Adherence to treatment in children and adolescents with cystic fibrosis: a cross-sectional, multi-method study investigating the influence of beliefs about treatment and parental depressive symptoms

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Nicola A Goodfellow ◽  
Ahmed F Hawwa ◽  
Alastair JM Reid ◽  
Rob Horne ◽  
Michael D Shields ◽  
...  
2021 ◽  
Author(s):  
Maria Serra ◽  
Anna Presicci ◽  
Luigi Quaranta ◽  
Maria Rosaria Erminia Urbano ◽  
Lucia Marzulli ◽  
...  

Abstract Background Children and adolescents and low-income individuals are considered particularly vulnerable for mental health implications during the current COVID-19 pandemic. Depression is one of the most frequent negative emotional responses during an epidemic outbreak, mainly due to the imposed restriction of social contacts. We aimed to assess depressive symptomatology in a sample of Italian low-income minors and to determine if pandemic-related stressors and pre-existing neuropsychiatric diagnoses would behave as risk factors for depressive symptoms. Methods We performed a cross-sectional study during July 2020, at the end of the Italian first wave of COVID-19 pandemic. We recruited 109 Italian socioeconomically disadvantaged children and adolescents, from 7 to 17 years. We used an online survey to collect socio-demographic and clinical data and information about pandemic-related stressors, and to assess depressive symptoms with the Children’s Depression Inventory 2 (CDI 2), Parent Version (Emotional Problems subscale) and Self-Report Short Form. We performed logistic regression analysis to assess the association between depressive symptoms and potential risk factors for mental health. Results 22% and 14% of participants showed depressive symptoms at the CDI 2 Parent Version and Self-Report, respectively. Participants coming from families experiencing a lack of basic supplies during the pandemic (34.9%) were more expected to show depressive symptoms at CDI 2 Parent Version. Participants with a pre-existing neuropsychiatric diagnosis (26.6%) were more likely to exhibit depressive symptoms measured by CDI 2 Parent Version. Conclusions The results of our study may be representative of a particular group of frail subjects, the socioeconomically disadvantaged children and adolescents, who were more vulnerable to depressive symptoms if they suffered from a paucity of essential supplies during the pandemic or had pre-existing neurodevelopmental disorders. The promotion of educational and child-care programs and activities could be crucial in sustaining the prevention of mental distress in those frail subjects who particularly need support outside the family.


2020 ◽  
Vol 38 ◽  
Author(s):  
Nelbe Nesi Santana ◽  
Célia Regina Moutinho de Miranda Chaves ◽  
Christine Pereira Gonçalves ◽  
Saint Clair dos Santos Gomes Junior

ABSTRACT Objective: To verify the association between quality of life, functional capacity and clinical and nutritional status in children and adolescents with cystic fibrosis (CF). Methods: Cross-sectional study, including patients from eight to 18 years old with CF. Quality of life, functional capacity, nutritional status and clinical status were evaluated with the Cystic Fibrosis Questionnaire; the 6-minute walk test (6MWT) and manual gripping force (MGF); the height percentiles for age and body mass index for age and respiratory function test, respectively. Pearson and Spearman correlation tests and logistic regression were used to analyze the data. Results: A total of 45 patients, 13.4±0.5 years old, 60% female, 60% colonized by Pseudomonas aeruginosa and 57.8% with at least one F508del mutation participated in the study. When assessing the perception of quality of life, the weight domain reached the lowest values, and the digestive domain, the highest. In the pulmonary function test, the forced expiratory volume of the first second was 77.3±3.3% and the 6MWT and MGF presented values within the normal range. There was an association between quality of life and functional capacity, nutritional status and clinical status of CF patients. Conclusions: The study participants had good clinical conditions and satisfactory values of functional capacity and quality of life. The findings reinforce that the assessment of quality of life may be important for clinical practice in the management of treatment.


2016 ◽  
Vol 7 (2) ◽  
pp. 17
Author(s):  
Jadiel Fellipe Santana Santos ◽  
Ana Carolline Rodrigues Lima ◽  
Clarissa Maria Dias Mota ◽  
Cristiane Franca Lisboa Gois ◽  
Gabriela Menezes Gonçalves De Brito ◽  
...  

Objetivo: avaliar a qualidade de vida (QV), sintomas depressivos e adesão ao tratamento de pessoas com Hipertensão Arterial Sistêmica (HAS). Metodologia: estudo do tipo descritivo exploratório, de corte transversal e abordagem quantitativa, realizado com a população de 155 usuários. Foram utilizados quatro instrumentos para a coleta de dados: um para caracterização sóciodemográfica e clínica, o Medical Outcomes Study 36 (SF-36), o Inventário de Depressão de Beck (BDI) e a Medida de Adesão aos Tratamentos (MTA). Os dados foram analisados segundo testes estatísticos e regressão linear simples. Resultados: o domínio mais comprometido da QV foi Aspecto físico (Média = 49,0); 34,8% apresentaram disforia, e 14,2% depressão moderada; 76,8% aderiam ao tratamento. Conclusão: as atividades avaliadas no domínio Aspecto físico da QV foram as mais comprometidas. A maioria dos sujeitos apresentou alteração psicológica e aderiu ao tratamento medicamentoso.Descritores: Qualidade de vida; Hipertensão; Depressão; Adesão à medicação.QUALITY OF LIFE, DEPRESSIVE SYMPTOMS AND ADHERENCE TO TREATMENT OF PEOPLE WITH HYPERTENSIONObjective: to evaluate the quality of life (QOL), depressive symptoms and adherence to treatment of people with Hypertension. Methodology: the study type is descriptive exploratory, cross-sectional and quantitative approach, with a total of 155 user as a target population. For data collection, four instruments were used: one for sociodemographic and clinical characterization, the Medical Outcomes Study 36 (SF-36), the Beck Depression Inventory (BDI) and the Measurement of Treatment Adherence (MTA). Data analyzes was performed with statistic tests and linear regression. Results: the most compromised domain of QOL was physical aspect (mean = 49.0); 34.8% of subjects had dysphoria, and 14.2% moderate depression; 76.8% had adhered to treatment. Conclusion: the activities evaluated in the physical domain of QOL were the most compromised. Most of subjects showed psychological change and adhere to drug treatment.Descriptors: Quality of life; Hypertension; Depression; Medication adherence.CALIDAD DE VIDA, SÍNTOMAS DEPRESIVOS Y LA ADHESIÓN A LAS PERSONAS CON TRATAMIENTO DE LA HIPERTENSIÓNObjetivo: evaluar la calidad de vida (CV), síntomas depresivos y la adherencia al tratamiento de las personas con hipertensión arterial sistêmica (HAS). Metodología: estudio exploratorio descriptivo, transversal y de enfoque cuantitativo, realizado con 155 usuarios. Se utilizaron cuatro instrumentos para la recolección de datos: un para la caracterización sociodemográfica y clínica, el Medical Outcomes Study 36 (SF-36), el Inventario de Depresión de Beck (BDI) y la Medición de la adherencia al tratamiento (MTA). Para analisis de los datos se realizaron testes estadísticos y análisis de regresión lineal. Resultados: La zona más afectada de la CV fue el aspecto físico (media = 49,0); 34.8% tenían disforia, y el 14,2% depresión moderada; 76,8% adhiere al tratamiento. Conclusión: las actividades evaluadas en el dominio de aspecto físico de CV son los más comprometida. La mayoría mostró cambio psicológico y se adhieren al tratamiento farmacológico.Descriptores: Calidad de vida; Hipertensión; Depresión; Adherencia a la medicación.


2021 ◽  
pp. 000486742110314
Author(s):  
Laura Orlando ◽  
Katarina A Savel ◽  
Sheri Madigan ◽  
Marlena Colasanto ◽  
Daphne J Korczak

Context: Studies of child and adolescent internalizing symptoms and dietary pattern have produced mixed results. Objectives: To quantify the association between dietary patterns and internalizing symptoms, including depression, in children and adolescents. Data sources: Embase, PsycINFO, MEDLINE, Web of Science and Cochrane up to March 2021. Study selection: Observational studies and randomized controlled trials with mean age ⩽ 18 years, reporting associations between diet patterns and internalizing symptoms. Data extraction: Mean effect sizes and 95% confidence intervals were determined under a random-effects model. Results: Twenty-six studies were cross-sectional, 12 were prospective, and 1 used a case-control design. The total number of participants enrolled ranged from 73,726 to 116,546. Healthy dietary patterns were negatively associated with internalizing ( r = –0.07, p < 0.001, 95% confidence interval [–0.12, 0.06]) and depressive symptoms ( r = –0.10, p < 0.001, 95% confidence interval [–0.18, –0.08]). Effect sizes were larger for studies of healthy dietary patterns and internalizing and depressive symptoms using self-report versus parent-report measures, as well as in cross-sectional studies of healthy dietary patterns and depression compared to prospective studies. Unhealthy dietary patterns were positively associated with internalizing ( r = 0.09, p < 0.001, 95% confidence interval [0.06, 0.14]) and depressive symptoms ( r = 0.10, p < 0.01, 95% CI [0.05, 0.17]). Larger effect sizes were observed for studies of unhealthy dietary patterns and internalizing and depressive symptoms using self-report versus parent-report measures. Limitations: A lack of studies including clinical samples and/or physician diagnosis, and a paucity of studies in which anxiety symptoms were the primary mental health outcome. Conclusion: Greater depression and internalizing symptoms are associated with greater unhealthy dietary patterns and with lower healthy dietary intake among children and adolescents.


Author(s):  
Hyunsuk Jeong ◽  
Hyeon Woo Yim ◽  
Seung-Yup Lee ◽  
Hae Kook Lee ◽  
Marc N. Potenza ◽  
...  

AbstractBackground and aimsParental depressive symptoms may aggravate the effects of children’s emotional problems on risks for Internet gaming disorder (IGD). Here we examined the joint effects of children’s emotional problems and parents’ depressive symptoms on the incidence of IGD.MethodsA large prospective, population-based cohort tested potential interactions between children’s emotional problems, parents’ depressive symptoms, and incidence of high risk of IGD (HRIGD). Family dyads (n=2,031) that included children who were non-HRIGD at baseline completed assessments of childhood and parental affective symptomatology. HRIGD was assessed at baseline and 12 months. Relative excess risk due to interaction (RERI) estimated the magnitudes of interactions.ResultsIn terms of risk for the development of IGD, parental depression was 1.8 times greater, children’s emotional problems were 2.9 times greater, and both risk factors together were 6.1 times greater than the background risk, with the last two findings reaching statistical significance. The expected risk for the development of HRIGD was RR=3.7.Discussion and conclusionsChildren’s emotional problems demonstrated a particularly strong relationship with HRIGD. Joint effects of children’s emotional problems and depressive symptoms in parents on the incidence of HRIGD were stronger than the sum of the independent effects of each factor. The findings suggest that combining interventions for the treatment of children’s emotional problems and parents’ depressive symptoms may have extra risk reduction effects on preventing IGD in children and adolescents.


2020 ◽  
Vol 38 ◽  
Author(s):  
Bianca Sampaio Bonfim ◽  
Valmir Machado de Melo Filho ◽  
Fernanda Matos Fontenelle ◽  
Edna Lúcia Souza

ABSTRACT Objective: To evaluate the level of self-referenced treatment adherence (TA) and its association with clinical and sociodemographic variables in patients with cystic fibrosis assisted at a reference center, as well as compare the level of self-referenced TA with that presumed by the multidisciplinary team. Methods: This is a cross-sectional study that included children and adolescents aged between 0-20 years with cystic fibrosis. Adolescents older than 14 years or their guardians, when younger than 14 years old, were interviewed using a standardized questionnaire. Professionals from the multidisciplinary clinic filled out another form with their impressions of the patients’ TA. Clinical and laboratory data were obtained in the medical records. The TA was considered satisfactory if the total adherence index (TAI) was equal or higher than 80%. Results: 53 patients were included with a median age of 112 months. The mean TAI was 83.2%. The mean TAIs for dornase alfa, pancreatic enzymes, continued use of inhaled tobramycin, vitamins supplements, nutritional supplements and dietary orientation was respectively: 86.1; 96.6; 78.6; 88.1; 51.8 and 78%. Children younger than 14 years presented better TA (p=0.021). The correlation between the self-referenced TA and the one presumed by the multidisciplinary team ranged from 0,117 to 0.402, being higher for Psychology and Nutrition professionals. Conclusions: The TAI was high particularly among children younger than 14 years. There was a positive correlation between the self-referenced TA and the one presumed by the Psychology (p=0.032) and the nutrition (p=0.012) professionals.


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