scholarly journals Dignity therapy intervention fidelity: a cross-sectional descriptive study with older adult outpatients with cancer

2022 ◽  
Vol 21 (1) ◽  
Author(s):  
Tasha M. Schoppee ◽  
Lisa Scarton ◽  
Susan Bluck ◽  
Yingwei Yao ◽  
Gail Keenan ◽  
...  

Abstract Objectives Intervention fidelity is imperative to ensure confidence in study results and intervention replication in research and clinical settings. Like many brief protocol psychotherapies, Dignity Therapy lacks sufficient evidence of intervention fidelity. To overcome this gap, our study purpose was to examine intervention fidelity among therapists trained with a systematized training protocol. Methods For preliminary fidelity evaluation in a large multi-site stepped wedge randomized controlled trial, we analyzed 46 early transcripts of interviews from 10 therapists (7 female; 7 White, 3 Black). Each transcript was evaluated with the Revised Dignity Therapy Adherence Checklist for consistency with the Dignity Therapy protocol in terms of its Process (15 dichotomous items) and Core Principles (6 Likert-type items). A second rater independently coded 26% of the transcripts to assess interrater reliability. Results Each therapist conducted 2 to 10 interviews. For the 46 scored transcripts, the mean Process score was 12.4/15 (SD = 1.2), and the mean Core Principles score was 9.9/12 (SD = 1.8) with 70% of the transcripts at or above the 80% fidelity criterion. Interrater reliability (Cohen’s kappa and weighted kappa) for all Adherence Checklist items ranged between .75 and 1.0. For the Core Principles items, Cronbach’s alpha was .92. Conclusions Preliminary findings indicate that fidelity to Dignity Therapy delivery was acceptable for most transcripts and provide insights for improving consistency of intervention delivery. The systematized training protocol and ongoing monitoring with the fidelity audit tool will facilitate consistent intervention delivery and add to the literature about fidelity monitoring for brief protocol psychotherapeutic interventions.

2020 ◽  
Vol 10 (4) ◽  
pp. 26674.1-26674.5
Author(s):  
Maryam Zaare Nahandi ◽  
◽  
Sayna Abbaszadeh ◽  
Mostafa Mansouri ◽  
Haniyeh Elahifard ◽  
...  

Background: Tramadol is a widely prescribed analgesic and due to its opioid-like effects, the potential for abuse of tramadol is noticeable. Besides, the complications of tramadol abuse have become a public health concern. This study aimed to investigate the affecting factors on the seizure, as one of the most common complications of tramadol consumption. Methods: A total number of 64 patients from 315 patients who were referred to Sina Hospital, Tabriz, Iran because of tramadol toxicity were included in this 9 months cross-sectional retrospective study. Results: There were 52 males and 12 females in the study. The seizure happened in 53.1% of the subjects and the Mean±SD time between tramadol consumption and seizure was 5.9±7.36 hours. There was no significant association between seizure and sex, age, the dose of tramadol, and previous tramadol consumption history. A significant association was seen between the dose of tramadol and the time of seizure. Conclusion: Seizure that happens due to tramadol overdose is not dependent on sex, age, and previous history of tramadol consumption. As the dose of tramadol is higher, the seizure happens later. More research is needed to understand why the seizure occurs later in higher doses.


2020 ◽  
Vol 26 (Supplement_1) ◽  
pp. S11-S12
Author(s):  
Cole Johnson ◽  
Edward Barnes ◽  
Xian Zhang ◽  
Millie Long

Abstract Background and Aims There are currently several recruitment challenges in randomized controlled trials (RCT) for inflammatory bowel disease (IBD) which prolong the drug approval process and affect the generalizability of study results. The purpose of this study is to characterize individuals who participate in IBD RCTs and identify factors which could influence future recruitment strategies. Methods We performed a cross-sectional study within the IBD Partners cohort comparing patients with current or prior participation in an interventional randomized controlled trial (RCT) of a medical therapy for IBD to those without any RCT participation. Bivariate statistics were used to compare RCT participation by IBD subtype and by other demographic and disease characteristics, and predictive modeling was used to identify factors predictive of RCT participation. We calculated the percent of the cohort that participated an in RCT during each calendar year from 2011–2018 and Clinicaltrials.gov was accessed to determine the number of active RCTs for IBD therapies per year during that same period. Results A total of 14,747 patients with IBD were included in the analysis and 1,116 (7.6%) reported RCT participation at any time. Demographic factors predictive of RCT participation (Table 1) included following at an academic institution (OR=1.8; 95%CI: 1.51–2.04) and age 36–75 (OR=1.6; 95%CI: 1.43–1.87). Patients with Crohn’s disease (CD) were more likely to participate than those with ulcerative colitis (UC) (OR=1.5; 95%CI: 1.35–1.77). Patients with more severe disease were more likely to participate, including those with prior IBD-related hospitalization (OR=2.6; 95%CI: 2.19–2.99), IBD-related surgery (OR=2.5; 95%CI: 2.24–2.87), biologic exposure (OR=3.2; 95%CI: 2.76–3.65), and “Poor” or worse quality of life (OR=1.7; 95%CI: 1.45–1.93). Steroid-free remission was associated with lower likelihood of RCT participation (OR=0.6; 95%CI: 0.53–0.70). While the number of active RCTs for IBD more than doubled between 2011 and 2018, RCT participation rates during that same time period decreased from 1.1% to 0.7% of the cohort (Figure 1). Conclusions RCT participation rates declined within this cohort between 2011–2018. Groups underrepresented in RCTs for IBD included younger patients, patients followed in community settings, and patients with more mild disease. The non-RCT group had mean sCDAI and SCCAI scores that did not meet remission thresholds, demonstrating populations in need of alternate therapies for whom clinical trials could be an option. Given anti-TNF exposure rates in this national cohort, studies should focus on anti-TNF failure populations. Investigators should make every effort to offer RCTs to all patients and network with community providers to increase awareness of RCTs.


2021 ◽  
Vol 15 (5) ◽  
pp. 1399-1402
Author(s):  
H. J. Mahmood ◽  
R. H. Ibrahim ◽  
M. F. Abdulghani ◽  
Z. F. Al-Zaidy

Background and aim: The Objectives of the present study to determine the VV among people with different background occupations in the City of Mosul, Iraq. Materials and method: A cross-sectional study was performed at Mosul Teaching Hospital between November 2019 and February 2020. Two hundred people who were physically examined represented different jobs in Iraqi society (Nurses, address, Policemen, and teachers). A physical examination was conducted of all participants who agreed to engage in this study. Results: The overall prevalence rate of VV among different occupational backgrounds in the City of Mosul is 19.5%. The study found that the percentage of men (50.5%) and women (49.5%). Most of the patient was beyond to age group (41-45) years and the mean age of the participants was (39.1+3.1). According to the BMI, the results indicated that most subjects belong to a class<30 (77%). Conclusions: The nurses will seek to prevent excessive extended occupational standing and using sitting or walking when appropriate. As a result, an improvement in clinical practice may reduce the incidence of vascular disease. Keywords: Varicose, Veins, Occupational


2020 ◽  
Vol 27 (08) ◽  
pp. 1595-1601
Author(s):  
Shahid Rasool ◽  
Salman Azhar ◽  
Talha Munir ◽  
Mian Sajjad Ahmad ◽  
Rizwan Abbas ◽  
...  

Hepatic encephalopathy (HE), a syndrome observed in some patients with cirrhosis, with depressed level of consciousness. Lactulose as well as lactitol has been used in the treatment of HE. Lactitol is comparable to lactulose in the treatment of HE with fewer side effects and better tolerated. However, literature showed equal efficacy of both drugs. So we conducted this trial to find better drug to implement its use in future. Objective: To compare the effectiveness of lactulose and lactitol in patients with acute hepatic encephalopathy. Study Design: Randomized Controlled Trial. Setting: Department of Medicine OPD and Emergency (East, West, North, South), Mayo Hospital, Lahore. Period: 6 Months June 2017 to Dec 2017. Material & Methods: 570 patients were included through non-probability, consecutive sampling after informed consent. Initial grade of HE was assessed and patients were randomly divided in two groups by using lottery method i.e. lactulose or lactitol. Patients were admitted to ward for management and kept under observation for 5 days. After 5 days, HE grades was measured again, then improvement in grade of HE (effectiveness) was measured. All data was entered and analyzed by using SPSS version 21.0. Chi-square was applied to compare both groups for effectiveness taking p-value≤0.05 as significant. Results: In this study the mean age of the patients was 44.22 ±11.81 years, the male to female ratio of the patients was 2.4:1. The mean duration of the cirrhosis of the patients was 3.73±1.61 months. In our study the effectiveness was achieved in 538 (94.39%) patients, out of which 263 cases were from lactulose group and 275 were from lactitol group and the difference was significant (p<0.0.5). Conclusion: Our study results concluded that Lactitol is better choice for the treatment of patients with acute hepatic encephalopathy as compared to lactulose. More efficacy was achieved in lactitol group patients than in lactulose group patients.


2019 ◽  
Vol 5 (1) ◽  
pp. 26-31
Author(s):  
Thinley Dorji ◽  
Sangay Wangmo ◽  
Krit Pongpirul

 Introduction: In Bhutan, pubertal and adolescent female students (10-19 years) make up 8.5% of the population. The need for menstrual hygiene management (MHM) is more urgent in post-menarcheal female students and in resource-poor settings. However, until recent time, there were strong socio-cultural barriers to discourses on menarche and MHM. This study was conducted to determine the age of menarche among Bhutanese female students to identify when to offer MHM support, their knowledge on menstruation and practices related to menstrual hygiene. Methods: This was a cross-sectional survey of female students studying in Grade 10 in Thimphu, Bhutan. A multistage clustered sampling was used. Data was collected using a self-administered questionnaire developed for the purpose of this study. Results: A total of 439 post-menarcheal female students were interviewed. The mean age of menarche was 12.8±1.1 years, and fear (38.3%) and confusion (25.1%) were the commonest responses. The mean score on knowledge on menstruation and MHM was 5.9±1.5 out of 9. The proportion of students with good knowledge was 36.7%. The common sources of information were the mother, teacher, and sister. The majority used commercial pads (92.5%) while some used clean cloths (5.7%) and tampons (1.6%). The proportion who stayed absent from school during menstruation in the month prior to data collection was 9.8%. Visiting religious places (67.6%) and participating in sports (4.3%) were common restrictions during menstruation. Conclusions: Female students experience difficulties in menstrual hygiene management in schools. Menstruation could lead to missing schools and other activities.  Keywords: Developing country; Health behaviour; Menstrual hygiene product; Standard of living.


2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Muhammad Umar Younis ◽  
Muhammad Zeeshan Sarwar ◽  
Sanad Saad

Introduction: Appendicitis is a condition characterized by inflammation of the appendix and is considered to be the most common emergency encountered in surgical practice. Compared with the open technique for appendectomy, laparoscopic appendectomy has less operative time, hospital stay and rate of complications and has been deemed as a safe and feasible procedure for the treatment of acute appendicitis. The use of endoclips for stump closure has been described to be comparable to other existing techniques with regards to clinical outcomes. However, controversies exist in literature regarding operative time with endoclip application. Objectives: To assess mean operative time for laparoscopic appendectomy using specially designed Double Shanked (DS) endoclips and assessing advantages in the form of better cosmesis, less pain. Study Design: Cross sectional exploratory study using non-probability sampling technique. Setting: West Surgical Ward of Mayo Hospital Lahore. Period: Period of 9 months from April 2014 through to December 2014. Materials and Methods: 120 successive patients fulfilling inclusion criteria were enrolled in the study. Clinical data with respect to their demographic profile (age and sex) were recorded. Laparoscopic Appendectomy was performed or supervised by one consultant. Quantitative variables such as age and operative time was analyzed and mean and standard deviation were calculated. Results: Our study results showed the mean age of the patients to be 25.84±8.09 years. There were 63.3% males whereas 36.7% were females. The mean operative time of the patients was noted to be 0.99±0.39 hours. Conclusions: The study results lend credence to the fact that Laparoscopic Appendectomy with endoclips is a safe, effective technique and has an admissible short operative time which when combined with better cosmesis, lesser pain and faster recovery, give it validity and acceptability. Our results generated for the local population will influence our management strategy for acute appendicitis in our set up.


2018 ◽  
Vol 21 (02) ◽  
pp. 386-390
Author(s):  
Alina Saqib ◽  
Saeed Sattar Shaikh ◽  
Jawad Mumtaz Sodhar

Objectives: Recognition of various gall stones in the patients attending surgicalOPD by biochemical analysis of gall stones. Study design: Cross sectional study. Place &duration of study: ISRA Hospital, Hyderabad and Institute of Biochemistry Sindh UniversityJamshoro. Duration of study was 18 months. Methods: Cases were patients with gall stones whowere diagnosed on ultrasonography. Gall stone analysis was done from Institute of BiochemistrySindh University Jamshoro. A total of sixty nine subjects were included in the study. Results: Inthe present study the mean Age was 35.81+ 8.12 years. Frequencies in different age groups are15-24 (11.60%), 25-34 (24.64%), 35-44 (53.63%), 45-54 (8.69%), 55-64 (01.45%). Age distributionis shown in Graph III-1. In the present study 49(71.0%) were females and 20(29%) were maleswith the female to male ration of 2.45:1. gender distribution is shown in Graph III-2. In the presentfrequencies of different types of gall stones was, cholesterol stones 38(55.07%), pigmentedstones 20(28.99%) and mixed type of stones 11(15.94%). Frequencies of different types of gallstones is shown in Graph III-3. Conclusions: In our study the frequency of cholesterol gall stoneis more as compared to pigmented and mixed gall stones. A total of 55.07% of cholesterolgallstones were found in our study with the female predominance.


PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0240152
Author(s):  
Shabir Ahmad Dar ◽  
Syed Quibtiya Khurshid ◽  
Zaid Ahmad Wani ◽  
Aaliya Khanam ◽  
Inaamul Haq ◽  
...  

Background Coronavirus disease-19 (COVID-19) has not only spawned a lot of stigma and discrimination towards its survivors but also to their corpses. We aimed to assess the magnitude and correlates of stigma in these survivors, on return to their communities. Methods This was a cross-sectional, hospital-based, exploratory study conducted by the postgraduate department of psychiatry, in collaboration with the postgraduate department of chest medicine, Govt. medical college, Srinagar. The study was performed among COVID-19 survivors, who attended the outpatient department after their discharge from the hospital. Socio-demographic characteristics were recorded through semi-structured proforma. Stigma was measured by the stigma questionnaire. Data was analyzed using descriptive statistics and regression analysis. Results A total of 91 survivors consented to participate in the study. Almost half (46.2%) of them were in the age group of 30–49 years and close to two-thirds (68.1%) were males. About three–fourths (74.7%) were from the urban background. The mean time from hospital discharge to study entry was 11.7±5.1 [Range(R) = 7–21] days. 98% of survivors provided at least one stigma endorsing response and the total mean stigma score was 28.5±7.1[R = 6–39]. The mean stigma sub-scores were highest for enacted stigma (7.6±1.8) [R = 2–9] and externalized stigma (15.0±4.1) [R = 1–20]. Enacted stigma was significantly high in males as compared to females. Enacted stigma and internalized stigma were both associated with education. Enacted stigma, externalized stigma, disclosure concerns, and total stigma was significantly associated with the occupation. Being unemployed and time since discharge were identified as independent predictors of total stigma. Conclusion Our study results showed high levels of enacted and externalized stigma among COVID-19 survivors. Enacted stigma was more among males and in those who were highly educated. Survivor centered and community-driven anti-stigma programs are the need of the hour to promote the recovery and community re-integration of these survivors.


BMC Nursing ◽  
2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Reza Nemati ◽  
Masoud Bahreini ◽  
Shahnaz Pouladi ◽  
Kamran Mirzaei ◽  
Farkhondeh Mehboodi

Abstract Background Establishment and improvement of patients’ trust in healthcare organizations like hospitals necessitate delivery of high-quality services by nurses, as the largest group of healthcare providers. The present study aimed to compare hospital service quality based on the HEALTHQUAL model and trusting nurses at university and non-university hospitals in Iran. Methods This comparative cross-sectional study was conducted on 990 patients admitted to university and non-university hospitals located in Bushehr Province, southern Iran, who were selected using the stratified random sampling method. The data were collected through the HEALTHQUAL questionnaire and the Trust in Nurses Scale, and then analyzed via the SPSS Statistics software (version 22) as well as the General Linear Model (GLM) univariate procedure and the Chi-square test with a significance level of 0.05. Results The study findings revealed that the mean values of real quality (perceptions) and ideal quality (expectations) were 3.89 ± 0.69 and 4.55 ± 0.47, respectively. The gap between the real and ideal quality (− 0.64) was also larger at non-university hospitals from the patients’ viewpoints. Comparing various dimensions of service quality, the largest gap at university and non-university hospitals was associated with “environment” (− 0.13) and “empathy” (− 0.18), respectively. Additionally, the mean scores of the patient trust in nurses at university and non-university hospitals were 10.34 ± 5.81 and 8.71 ± 4.05, respectively, being a statistically significant difference (p <  0.001). Conclusion The study results demonstrated that hospital service quality and trusting in nurses were at higher levels at the university hospital than the non-university one; however, hospital service quality was at a lower level than what the patients had expected. Accordingly, hospital managers and policy-makers were suggested to focus on patients to reduce gaps in service quality, to promote service quality, and to provide better healthcare services to patients.


SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A435-A435
Author(s):  
M Colon-Feliciano ◽  
N Prats ◽  
A Sierra-Gonzalez ◽  
G Jovet ◽  
L Jimenez

Abstract Introduction Wake-up stroke (WUS) is a stroke that occurs during sleep and accounts for 14-29.6% of all acute ischemic stroke (AIS) cases. The use of intravenous alteplase, the therapeutic standard, requires identifying time of stroke onset. Recent studies suggest that obstructive sleep apnea (OSA) is an independent risk factor for WUS. This study aims to describe a population of Puerto Rican Veterans with WUS and to evaluate clinical differences between patients WUS and non-WUS (NWUS). Methods The study was a cross-sectional analysis of all patient records with AIS from April 2018 to July 2019. One hundred forty records were reviewed. Patients who woke up with new AIS symptoms were labeled as WUS. Study variables included demographics, comorbidities, medications, sleep disorders, prior stroke, administration of alteplase and the National Institute of Health Stroke Scale (NIHSS). Results Among 140 participants predominantly male (98.6%), 27.1% had WUS. The mean age was 75 (range 21-89). NIHSS mean was 5.9. Comorbidities for WUS vs NWUS were as follows: overweight or obese (60% vs 62.6% p=0.667), hypertension (100% vs 95.1% p=0.323), hyperlipidemia (95% vs 93% p=0.999), diabetes mellitus (55.3% vs 67% p=0.212), atrial fibrillation (26.3% vs 24.5% p=0.826), anxiety (36.8% vs 33.3% p=0.697), depression (55.3% vs 51.0% p=0.652), non-smokers (89.% vs 89%), smokers (10.5% vs 11.1%), and prior stroke (34.2% vs 35.3% p=0.905). Insomnia was observed in 42% vs 40% (p= 0.838) and 24% vs 23% (p=0.955) had OSA. Conclusion There were no significant differences in clinical characteristics between patients with WUS and NWUS in this sample of Puerto Rican Veterans. OSA was less prevalent than previously reported. Lack of recognition of OSA as a risk factor for stroke and under-diagnosis of OSA might explain the study results. Support  


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