scholarly journals Identification of blood immune and metabolic indicators explaining the variability of growth of pigs under contrasted sanitary conditions

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
N. Le Floc’h ◽  
F. Gondret ◽  
R. Resmond

Abstract Background Health and growth of pigs are affected by the hygiene of housing. Lower growth performance observed in poor hygiene of housing conditions is explained by reduced feed intake and metabolic changes caused by the activation of body defences. In a previous experiment, we reported contrasted average values of body weight gain, concentrations of circulating metabolites, redox and immune indicators in blood of pigs housed in good or poor hygiene conditions during the growing period. This study addressed inter-individual variability in these responses to determine whether a particular blood profile explains average daily gain (ADG) of the pig. Results The data originated from 160 growing pigs, half of which subjected to a hygiene challenge for 6 weeks (W0 to W6) and the others housed in good hygiene conditions. Pigs originated from two lines divergently selected for residual feed intake (RFI). Individual body weights were recorded during this period, and relative ADG (rADGW0-W6) was calculated as the ADG corrected by the initial body weight measured at W0. Blood samples were taken before (W0) and 3 weeks (W3) after the beginning of the challenge. The analysed dataset consisted of 51 metabolites and indicators of immune and inflammatory responses measured on 136 pigs having no missing value for any variables, when calculated as the differences W3 minus W0 in circulating concentrations. An algorithm tested all possible linear regression models and then selected the best ones to explain rADGW0-W6. Six variables were identified across the best models and correlated with rADGW0-W6 with a goodness of fit (adjusted R2) of about 67%. They were changes in haptoglobin, global antioxidant capacity of plasma (Biological Antioxidant Power or BAP), free fatty acids, and 3 amino acids: leucine, tryptophan, and 1-methylhistidine. The effects of housing conditions and RFI lines were comprised in the variables of the selected models and none of these conditions improved accuracy of the predictive models, leading to genericity of the pinpointed metabolic changes in relation to variability of ADG. Conclusions This approach allows us to identify blood variables, whose changes in blood concentrations correlated to ADG under contrasted sanitary conditions.

2021 ◽  
Vol 43 (1) ◽  
pp. 254-262
Author(s):  
A. O. Aniebo

The effect of dietary treatments on growth performance, haematological and biochemical indices of finisher broilers as well as economics of broiler production were determined in this fermented cassava flour/blood mixture code-named "cassablood". The control diet (T1) contained 0% cassablood, while diets 2, 3 and 4 contained 20%, 25% and 30% cassablood respectively. 120 four weeks old Anak broiler chicken were randomly allocated the 4 diets with 30 birds per treatment replicated 3 times with ten 10 broilers per replicate in a completely randomized design (CRD). Treatment effects on final body weight, final weight gain, feed intake and seed conversion ratio were significant (P<0.05). Birds fed cassablood based diets compared favourably with the control diet. 20% cassablood inclusion performed equally with the control diet in feed intake, body weight gain and feed conversion ratio.All dietary groups also showed no significant differences (P>0.05) in most haematological and serum biochemical indices of broilers except in cholesterol, glucose and triglyceride contentswhichdiffered (P<0.05) significantly. Similarly, chicken on 20% and 25% inclusion levels produced significantly (P < 0.05) higher economic gains in terms of feed cost per kilogram of broiler among all the treatments. Therefore, 20 - 25% cassablood dietary inclusion level was recommended in broiler diet for production and profit maximization.  


2018 ◽  
Vol 16 (1) ◽  
pp. 23-29 ◽  
Author(s):  
M. M. Rahman ◽  
M. S. Hossain ◽  
M. H. Abid ◽  
M. R. Nabi ◽  
M. A. Hamid

A study was conducted with green tea powder to evaluate the effect on broiler growth, meat quality and the development of internal organ. The broiler growth, meat quality and the blood profile have been improving day by day by using green tea powder with poultry feed. The experiment design should be well planned. Biosecurity of experimental design was maintained properly. Feed intake, feed conversion ratio is efficient in experiment birds. The live weight gain was significantly (P<0.05) higher in the group of Green Tea in the feed. The initial body weights of group To, T1, T2, T3 and T4 day of the experiment were 176.8 ±1, 184.2±1.3, 185.1±1, 190.2±084, 180.2±1.22 gm respectively and after 35th day of experiment final body weight were 1972±3.22, 1992±2.77, 1940±3.17, 1778±3.52, 1918±2.81 gm respectively. The net body weight gains were 1795.2±2.22, 1807.8±1.47, 1754.9±2.17, 1727.8±2.68, 1737.8±1.52 gm respectively and economics of production were analyzed and found the net profit per broiler. Green tea powder has significantly impact on feed intake To, T1, T2, T3 and T4 respectively 3058± 4.23, 2971±4.01, 2995±5.57, 3208±4.3 and 3226±5.25 and increase body weight. Here the total cholesterol is lower in the group of broiler supplied green tea 0.5% and compare to other group of GT and antibiotic group. Triglyceride level showed significant (P<0.01) differences among different groups where highest level was found in T1 and lowest in T3 groups  due to green tea powder concentration of blood plasma of broiler chicken.


Animals ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 1017
Author(s):  
Jordi Camp Montoro ◽  
Edgar Garcia Manzanilla ◽  
David Solà-Oriol ◽  
Ramon Muns ◽  
Josep Gasa ◽  
...  

This study aimed to (1) investigate the effect of birth and weaning body weight (BW) on performance indicators of grow-finisher pigs and (2) estimate birth and weaning BW cut-off values in order to identify slow growing pigs (SGP). Pigs (n = 144) were classified as SMALL (0.9 ± 0.13 kg) or BIG (1.4 ± 0.20 kg) at birth and re-classified as SMALL (5.4 ± 1.6 kg) or BIG (6.3 ± 1.91 kg) at weaning. Individual BW was recorded bi-weekly, and feed intake was recorded on a daily basis. Average daily gain (ADG) and feed intake, feed conversion ratio (FCR) and days to target slaughter weight (TSW) were calculated. SMALL–SMALL pigs had lower ADG (p < 0.05) requiring 167.1 days (i.e., 14.2 extra days) to TSW (p < 0.05) compared with BIG pigs at birth and/or weaning. However, FCR was similar between groups (p > 0.05). Pigs weaned at <3.7 kg BW would likely be SGP. Pigs born at ≥1.1 kg BW or weaned at ≥6.4 kg BW are more likely to reach TSW at 22 weeks of age. The results suggest that birth BW might not be the best predictor for subsequent performance, as some small-born pigs were able to catch up with their bigger counterparts. The cut-off values identified could be used to design specific management and nutritional strategies for SGP.


1971 ◽  
Vol 13 (1) ◽  
pp. 51-57 ◽  
Author(s):  
S. R. Morrison ◽  
L. E. Mount

SUMMARYPigs fed ad libitum were exposed to changes from 22 to 33°C and from 33 to 20°C. Responses were investigated in two groups of animals kept for three successive periods of four weeks at 22°, 33° and finally 20°C.Twenty-four hr after the first change, from 22 to 33°C, there was a decline in body weight; after the second change, from 33 to 20°C, there was a large increase. After the change to 33°C, feed intake by the second day and growth rate for the first week were about the same as at the end of the four weeks, but about 12 days were required for water intake, rectal temperature and respiratory rate to reach steady values.After the change from 33 to 20°C, steady values for respiratory rate and rectal temperature were reached in one and 12 days respectively. The rate of gain in weight increased to reach a peak nine days following the temperature change and then declined.


2021 ◽  
Vol 43 (2) ◽  
pp. 272-283
Author(s):  
M. I Okoruwa ◽  
M. K Adewumi ◽  
I. Ikhimioya

The study was carried out to assess the performance characteristics and blood profile of growing rams fed mixture of bamboo leaves and neem seed cake. Eighteen West African dwarf rams with an average weight of 8.00±0.20kg and aged between 8-9 months were randomly allotted to three dietary treatments with six animals per treatment group in a completely randomized design. The diets compared were TD1 (70% Guinea grass with 30% concentrate diet which was the control group), TD2 (mixture of 50% bamboo leaves with 20% neem seed cake and 30% concentrate diet) and TD3 (combination of 45% bamboo leaves with 25% neem seed cake and 30% concentrate diet). The results obtained indicated that average total feed intake (11.13kg), average daily feed intake (132.50g), mean corpuscular haemoglobin concentration (33.35g/dL), glucose (59.01mg/dL), cholesterol (42.89mg/dL), creatinine (1.01mg/dL) and urea (13.73mg/dL) were significantly (P<0.05) better with animals on TD1 . Animals on TD2 had the highest values in terms of finial body weight (11.33kg), average total weight gain (3.27kg), average daily weight gain (38.93g), total digestible nutrient (68.97%), packed cell volume (30.06%), haemoglobin (10.68g/dl), red blood cell (9.42 x 106/.ml), mean corpuscular haemoglobin (11.70Pg), total protein(8.09g/dL), albumin (3.03g/dL), and globulin (5.06g/dL). Feed conversion ratio (4.27), mean corpuscular volume (30.95fl) and white blood cell (2.56 x 103/mL) were significantly highest for animals on TD3. No significant (P>0.05) difference existed between the experimental rams with regards to initial body weight, lymphocyte, neutrophile. It was concluded that combination of 50% bamboo leaves with 20% of neem seed cake and 30% concentrate diet improved performance, haematological and serum biochemical indices for growing rams


1963 ◽  
Vol 43 (2) ◽  
pp. 294-302 ◽  
Author(s):  
J. E. Troelsen ◽  
J. M. Bell

The relative feed intake, feed efficiency and carcass characteristics of growing pigs and mice were studied to determine the value of the mouse as a pilot animal in pig nutrition research. Fifteen rations were fed in two experiments to 120 pigs and 120 mice. They were composed of equal parts of wheat and barley, plus one of three levels each of oat hulls, alfalfa meal, wheat bran, cellulose, and corn-cob meal to produce mixtures containing an estimated 62, 65, and 68 per cent of total digestible nutrients. With pigs, data were obtained on feed and growth from 100 to 200 pounds live weight; carcass measurements were made on the slaughtered barrows at 200 pounds. Feed and growth records of mice were kept for 14 days commencing at weaning; the carcasses were then analysed for water, fat, protein and ash.The relative response of the two species is indicated by the following correlation coefficients: feed consumption (0.67); digestibility of dry matter (0.96); digestibility of energy (0.87); consumption of digestible energy (0.79); rate of gain (0.63), and per cent fat in mouse carcasses and back fat thickness in the barrows (0.70). The correlation between per cent fat in mouse carcasses and the R.O.P. score for barrows was −0.67.The mean ratio of swine and mice was 581:1 for physiological body weight (kg.0.75), 693:1 and 654:1 for consumption of dry matter, and digestible energy, respectively, reflecting a relatively greater feed capacity of pigs and a higher energy digestibility by mice. The corresponding ratios for the effects of changes in ration composition were 369:1, 331:1, and 462:1, indicating that the pigs were better equipped to cope with bulky rations. It was suggested that mice were more efficient in conversion of feed to body weight gain because in pigs a greater part of the gain was fat.


1980 ◽  
Vol 30 (1) ◽  
pp. 95-103 ◽  
Author(s):  
T. L. Veum ◽  
R. Lauxen ◽  
J.-T. Yen

ABSTRACTThe efficacy of feed additives in enhancing the performance of growing pigs, together with the effect of different protein levels (18 v. 16% from 13 to 18 kg body weight and 16 v. 14% from 18 to 39 kg body-weight), were evaluated in three experiments with 412 pigs. In Experiment 1, from 13 to 39 kg body weight, pigs receiving 55 p.p.m. carbadox (C) produced a greater (P<0·05) average daily live-weight gain than did the non-medicated (NM) pigs and those receiving 275 p.p.m. chlortetracycline-sulphamethazine-penicillin (ASP) with a similar but non-significant (P>0·05) trend n i daily feed intake and gain/feed ratio. The ASP pigs also produced a greater (P<0·05) weight gain than the NM pigs. The higher dietary protein level sequence produced a greater (JP<0·05) weight gain and gain/feed ratio.In Experiment 2, from 16 to 39 kg body weight, NM control pigs achieved high weight gains, and all the feed additive treatments studied [C+106 p.p.m. of the worming agent pyrantel tartrate (C+P); ASP+8 mg of the worming agent levamisole-HCl per kg body weight fed once on day 7 of the experiment (ASP+L); and 113 p.p.m. tylosin+13 p.p.m. of the worming agent hygromycin B] were similar to the NM controls in daily feed intake, weight gain and gain/feed ratio. However, in Experiment 3, the C+P and ASP+L treatments resulted in a greater (P<0·05) weight gain with a trend toward greater daily feed intake than did the NM control treatment from 17 to 35 kg. The weight gain of the ASP+L pigs was also greater (P<0·05) than that of 165 p.p.m. oxytetracycline and NM pigs from 35 to 57 kg. From 57 to 96 kg all the pigs received the same NM control diet and their weight gains were similar. The gain/feed ratio was similar among the treatments within each of the weight periods in Experiment 3. Pigs slaughtered at the beginning and at various stages during Experiments 2 and 3 were free of internal parasites and migration damage.


1994 ◽  
Vol 74 (2) ◽  
pp. 361-369 ◽  
Author(s):  
H. L. Trenholm ◽  
B. K. Thompson ◽  
B. C. Foster ◽  
L. L. Charmley ◽  
K. E. Hartin ◽  
...  

Three experiments were conducted to determine the effects of feeding diets containing laboratory synthesized deoxynivalenol (DON), or Fusarium (naturally) contaminated wheat containing DON on performance and health of young pigs (32.8–41.1 kg body weight). Diets containing 3.4–19.1 mg DON kg−1 were fed to pigs ad libitum for 14 d (exps. 1 and 2) or 7 wk (exp. 3) after which time each pig was slaughtered and blood, tissue and organ samples taken for analysis. All pigs responded to DON-contaminated diets with an immediate reduction in feed intake and body weight gain followed by some degree of recovery that was dependent on the dietary DON concentration. Negative linear relationships were found between feed intake or body weight gain and dietary DON concentration with pure DON and naturally contaminated wheat diets. Feed intake and weight gain were, respectively, 18 and 23% lower when a diet containing naturally contaminated wheat was fed compared to a diet containing an equivalent concentration of pure DON. Effects of DON on organ weights, relative to body weight, were inconsistent among experiments. The gastric mucosa was thinner and more eroded and had a higher degree of folding in the esophageal region in most groups fed DON-contaminated diets compared to those fed the control diet. Effects of DON on the fundic and cardiac regions of the stomach were inconsistent among treatments and experiments. There was little or no effect of DON on most of the blood parameters measured. Key words: Pure deoxynivalenol, naturally contaminated wheat, swine, intake, gain, vomitoxin, mycotoxin, fusarium, trichothecene


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