scholarly journals HEV prevalence and potential risk factors in a large multi-ethnic youth cohort in China

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Huixia Li ◽  
Yinxia Zhang ◽  
Zhongren Ma ◽  
Zewen Liu ◽  
Aqsa Ikram ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Age Groups ◽  
Serum Samples ◽  
Igm Antibodies ◽  
Ethnic Populations ◽  
Comprehensive Information ◽  
Potential Risk Factors ◽  
Youth Population ◽  
Commercial Enzyme Immunoassay

Abstract Background This cohort study was designed to investigate the prevalence of and potential risk factors of HEV infection in a large multi-ethnic youth cohort in China. Methods Blood samples were collected from participants (n = 6269) and serum was isolated. All serum samples were tested for anti-HEV IgG, anti-HEV IgM antibodies using commercial enzyme immunoassay kits (Wantai Biological Pharmacy Enterprise, Beijing, China). Results The overall rate of anti-HEV IgG and anti-HEV IgM prevalence was 4.78% and 0.14%, 0.03% were positive for both anti-HEV IgG and anti-HEV IgM antibodies. Anti-HEV IgG positivity is significantly higher in females (5.27%) compared to males (4.14%) (P = 0.028). Anti-HEV IgG prevalence is significantly (P = 0.0001) higher in Dong (17.57%), Miao (12.23%), Yi (11.04%), Gelao (9.76%), and Bai (10.00%) compared to other ethnic groups. It is significantly higher in Guizhou (11.4%), Sichuan (10.1%), Yunnan (9.3%), and Guangxi (6.9%) than that other province. We found that ethnicity and provincial background are significantly associated with HEV infection in this cohort. Conclusion This study provides comprehensive information on HEV prevalence in multi-ethnic populations in China. However, our study only focused on a youth population from different provinces of China. Future studies are recommended to investigate HEV prevalence in other age groups of the ethnic populations.

scholarly journals Sero-epidemiological survey of bluetongue disease in one-humped camel (Camelus dromedarius) in Kassala State, Eastern Sudan

2021 ◽  
Vol 74 (1) ◽  
Author(s):  
Molhima M. Elmahi ◽  
Mohammed O. Hussien ◽  
Abdel Rahim E. Karrar ◽  
Amira M. Elhassan ◽  
Abdel Rahim M. El Hussein
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Animal Health ◽  
Water Source ◽  
Economic Losses ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Samples ◽  
Cross Sectional ◽  
Potential Risk Factors ◽  
Eastern Sudan

Abstract Background Bluetongue (BT) is a vector-borne viral disease of ruminant and camelid species which is transmitted by Culicoides spp. The causative agent of BT is bluetongue virus (BTV) that belongs to genus Orbivirus of the family Reoviridae. The clinical disease is seen mainly in sheep but mostly sub-clinical infections of BT are seen in cattle, goats and camelids. The clinical reaction of camels to infection is usually not apparent. The disease is notifiable to the World Organization for Animal Health (OIE), causing great economic losses due to decreased trade and high mortality and morbidity rates associated with bluetongue outbreaks. The objective of this study was to investigate the seroprevalence of BTV in camels in Kassala State, Eastern Sudan and to identify the potential risk factors associated with the infection. A cross sectional study using a structured questionnaire survey was conducted during 2015–2016. A total of 210 serum samples were collected randomly from camels from 8 localities of Kassala State. The serum samples were screened for the presence of BTV specific immunoglobulin (IgG) antibodies using a competitive enzyme-linked immunosorbent assay (cELISA). Results Seropositivity to BTV IgG was detected in 165 of 210 camels’ sera accounting for a prevalence of 78.6%. Potential risk factors to BTV infection were associated with sex (OR = 0.061, p-value = 0.001) and seasonal river as water source for drinking (OR = 32.257, p-value = 0.0108). Conclusions Sex and seasonal river as water source for drinking were considered as potential risk factors for seropositivity to BTV in camels. The high prevalence of BTV in camels in Kassala State, Eastern Sudan, necessitates further epidemiological studies of BTV infection in camels and other ruminant species to better be able to control BT disease in this region.

scholarly journals Seroprevalence of infectious bursal disease and its potential risk factors in backyard chicken production of Waliso district, South Western Shoa Zone, Ethiopia

2021 ◽  
Vol 20 (1) ◽  
pp. 95-105
Author(s):  
Chala Bedasa ◽  
◽  
Ararsa Duguma ◽  
Asamenew Tesfaye ◽  
Tadele Tolosa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Animal Health ◽  
Infectious Bursal Disease ◽  
Flock Size ◽  
Serum Samples ◽  
Significant Difference ◽  
Bursal Disease ◽  
Potential Risk Factors ◽  
Backyard Chicken

A cross sectional study on infectious bursal disease was conducted in apparently healthy backyard chicken at Waliso district of Southwestern Shoa, central oromia, Ethiopia from from November, 2018 to October, 2019. A total of 282 chickens were randomly selected to estimate seroprevalence of IBD infection and to identify the likely potential risk factors for the disease. Serum samples collected and serological test conducted in laboratory at National Animal Health Diagnosis and Investigation Center Sebeta, Ethopia. Out of 282 serum samples tested 224 were positive for indirect ELISA technique and the overall seroprevalence of IBDV in the study area was found to be 79.43% at individual level. Educational level of owners, kebeles and flock size significantly affect seroprevalence of IBD in the study area. The effect of difference in managements like source of replacement, frequency of house cleaning, use of disinfectant and isolation practice has a significant effect on IBDV sero-prevalence. A lower seroprevalence of IBDV was reported in good hygienic level of house (26.7%) than poor level of chicken house hygiene (96.4%) with statistically significant difference (P < 0.05). The seroprevalence of IBDV in the present study associated with chicken management, flock size, owner education level and other animal related risk factors for occurrence of the disease. Therefore, awareness on chicken health management, and importance of immunization would help to minimize the prevalence of the disease and play crucial role in the control of the disease. Furthermore, characterizing virus strains circulating in the area in future study is recommended.

scholarly journals Seroprevalence and potential risk factors of bovine brucellosis at the livestock-wildlife interface area of Yankari game reserve, Bauchi State, Nigeria.

2020 ◽  
Vol 46 (4) ◽  
pp. 33-44
Author(s):  
Y. Ibrahim ◽  
H. M. Mai ◽  
D. J. U. Kalla ◽  
J. Kabir ◽  
J. Nathaniel
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Age Groups ◽  
Confirmatory Test ◽  
Enzyme Linked Immunosorbent Assay ◽  
Interface Area ◽  
Indigenous Cattle ◽  
Cross Sectional ◽  
Game Reserve ◽  
Potential Risk Factors

A cross-sectional study was conducted to determine the seroprevalence and associations with potential risk factors of brucellosis in indigenous cattle breeds at the livestock-wildlife interface area of Yankari Game Reserve, Bauchi State, Nigeria. A total of 1000 sera samples were examined from 44 herds using convenient and simple random sampling technique. Rose Bengal Plate Test (RBPT) and competitive Enzyme-linked Immunosorbent Assay (c-ELISA) were used as screening and confirmatory tests respectively. Of the 1000 samples, 23.5% samples were RBPT positive, and after the confirmatory test, the overall true animal-level prevalence was 4.1%. For the herd level prevalence, (47.7%) herds had at least one animal that is seropositive following both tests. Brucellosis seroprevalence was significantly associated with the following potential risk factors; herds that belong to a cooperative society member (p<0.042), herds that keep only cattle (p<0.001), herds that practice commercial farming system (p<0.011), herds that possess a herd size of 51 to 100 cattle (p?0.009) and herds that have no history of abortion and other reproductive disorder (p<0.009). No statistically significant differences in brucellosis seroprevalence was obtained within sex, breed and age groups It can be concluded that brucellosis is still endemic in the study area.

scholarly journals Suicide risk of old adults with special reference to aging

2017 ◽  
Vol 30 (4) ◽  
pp. 603-603
Author(s):  
Tomoyuki Kawada
Keyword(s):  
Risk Factors ◽  
Life Events ◽  
Potential Risk ◽  
Suicide Risk ◽  
Age Groups ◽  
Relationship Problems ◽  
Old Adults ◽  
Physical Conditions ◽  
Potential Risk Factors ◽  
Psychiatric Problems

Koo et al. (2017) compared differences in sociodemographic variables, recent life events, and mental and physical illnesses between three age groups (65–74 years, 75–84 years, and 85 years and over) who died by suicide. Psychiatric problems, suicidal behavior, legal and financial stressors, and relationship problems decreased with age. In contrast, physical conditions and bereavement increased with age. Suicide rates were increasing with age for males, but not for females. In addition, significant differences in the prevalence of potential risk factors within the three different age groups existed. I have some concerns about their study.

scholarly journals Risk Factors Underlying COVID-19 Lockdown-Induced Mental Distress

2020 ◽  
Vol 11 ◽  
Author(s):  
Jan Sebastian Novotný ◽  
Juan Pablo Gonzalez-Rivas ◽  
Šárka Kunzová ◽  
Mária Skladaná ◽  
Anna Pospíšilová ◽  
...  
Keyword(s):  
Mental Health ◽  
Risk Factors ◽  
Depressive Symptoms ◽  
Potential Risk ◽  
Mental Distress ◽  
Illness Perception ◽  
Age Groups ◽  
High Stress ◽  
Age Related ◽  
Potential Risk Factors

Recent reports suggest that the COVID-19 lockdown resulted in changes in mental health, however, potential age-related changes and risk factors remain unknown. We measured COVID-19 lockdown-induced stress levels and the severity of depressive symptoms prior to and during the COVID-19 lockdown in different age groups and then searched for potential risk factors in a well-characterized general population-based sample. A total of 715 participants were tested for mental distress and related risk factors at two time-points, baseline testing prior to COVID-19 and follow-up testing during COVID-19, using a battery of validated psychological tests including the Perceived Stress Scale and the Patient Health Questionnaire. Longitudinal measurements revealed that the prevalence of moderate to high stress and the severity of depressive symptoms increased 1.4- and 5.5-fold, respectively, during the COVID-19 lockdown. This surge in mental distress was more severe in women, but was present in all age groups with the older age group exhibiting, cross-sectionally, the lowest levels of mental distress prior to and during the lockdown. Illness perception, personality characteristics such as a feeling of loneliness, and several lifestyle components were found to be associated with a significant increase in mental distress. The observed changes in mental health and the identified potential risk factors underlying these changes provide critical data justifying timely and public emergency-tailored preventive, diagnostic, and therapeutic mental health interventions, which should be integrated into future public health policies globally.

Premature Arterial Disease Associated with Familial Antithrombin III Deficiency

1990 ◽  
Vol 63 (01) ◽  
pp. 013-015 ◽  
Author(s):  
E J Johnson ◽  
C R M Prentice ◽  
L A Parapia
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Potential Risk ◽  
Antithrombin Iii ◽  
Arterial Disease ◽  
Coagulation System ◽  
Early Age ◽  
Arterial Thromboembolism ◽  
Potential Risk Factors ◽  
Antithrombin Iii Deficiency

SummaryAntithrombin III (ATIII) deficiency is one of the few known abnormalities of the coagulation system known to predispose to venous thromboembolism but its relation to arterial disease is not established. We describe two related patients with this disorder, both of whom suffered arterial thrombotic events, at an early age. Both patients had other potential risk factors, though these would normally be considered unlikely to lead to such catastrophic events at such an age. Thrombosis due to ATIII deficiency is potentially preventable, and this diagnosis should be sought more frequently in patients with arterial thromboembolism, particularly if occurring at a young age. In addition, in patients with known ATIII deficiency, other risk factors for arterial disease should be eliminated, if possible. In particular, these patients should be counselled against smoking.

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