Neurological complications after cardiac surgery: a retrospective case-control study of risk factors and outcome

Asfiksia perinatal merujuk pada kekurangan oksigen selama persalinan, sehingga berpotensi menyebabkan kematian dan kecacatan. WHO memperkirakan 4 juta anak terlahir dengan asfiksia setiap tahun, dimana 1 juta di antaranya meninggal dan 1 juta anak bertahan hidup dengan gejala sisa neurologis yang parah. Penelitian ini bertujuan untuk menganalisis faktor risiko fetal dan tali pusat pada asfiksia neonatal.Penelitian dilakukan di lakukan di RS Dr Moewardi Surakarta dengan pendekatan quantitative retrospective case control study. Data diambil dari rekam medis antara tahun 2013-2018. Penelitan ini melibatkan 264 neonatal yang terdiri dari 88 kelompok kasus dan 176 kelompok control. Kelompok kasus adalah bayi dengan diagnosa asfiksia yang dilakukan analisis terhadap faktor risiko fetal, sedangkan bayi yang tidak mengalami asfiksia dijadikan kelompok kontrol. Hasil analisis statistik uji Chi-Square dan Fisher Exact ditemukan bahwa kelahiran prematur (OR 2,07 CI 95% P 0,02), persalinan dengan tindakan (OR 3,61 CI 95% P 0,00), berat bayi (OR 2,85 CI 95% P 0,00), posisi janin (OR 2,37 CI 95% P 0,05), tali pusat ( QR 3,071 CI 95% P 0,01) berisiko terhadap insiden asfiksia perinatal. Air ketuban yang bercampur meconium (OR 1,51 CI 95% P 0,16) tidak memiliki risiko dengan Asfiksia perinatal. Kesimpulan: Risiko terhadap insiden asfiksia perinatal meliputi kelahiran prematur, persalinan dengan tindakan, berat bayi, posisi janin, dan tali pusat.Perinatal asphyxia refers to a lack of oxygen during labor, which has the potential to cause death and disability. WHO estimates 4 million children born with asphyxia each year, in which 1 million dies and 1 million survive with severe neurological sequelae. This study aims to analyze fetal and umbilical risk factors in neonatal asphyxia.This research is a quantitative retrospective case-control study, which was conducted at The Dr. Moewardi hospital, Surakarta. Data was taken from medical records from 2013-2018. The case group was patients diagnosed asphyxia, while those who did not experience asphyxia were treated as a control group. A total of 264 samples, consisting of 88 case group respondents and 176 control group respondents. Statistical analysis Chi- Square and Fisher Exact found that preterm birth (OR 2.07 CI 95% P 0.02), labor with instrument or complication (OR 3.61 CI 95% P 0.00), infant weight (OR 2.85 CI 95% P 0, 00), fetal position (OR 2.37 CI 95% P 0.05), umbilical cord (QR 3.071 CI 95% P 0.01) are at risk for the incidence of perinatal Asphyxia. The amniotic fluid mixed with meconium (OR 1.51 CI 95% P 0.16) has no risk with perinatal asphyxia.The risk factors of incidences of perinatal asphyxia were preterm birth, labor with instrument or complication, baby weight, fetal position and umbilical cord.

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Risk factors for the development of significant postoperative bleeding after pediatric cardiac surgery with cardiopulmonary bypass: A nested case-control study

Research in Cardiovascular Medicine ◽

10.5812/cardiovascmed.43766 ◽

2017 ◽

Vol 6 (3) ◽

pp. 5

Author(s):

JuanCarlos Núñez-Enríquez ◽

IsabelZnaya Ramírez-Flores ◽

Maribel Ibarra-Sarlat ◽

Vivian Neme-Bechara ◽

Alejandro Herrera-Landero ◽

...

Keyword(s):

Risk Factors ◽

Cardiac Surgery ◽

Cardiopulmonary Bypass ◽

Case Control Study ◽

Postoperative Bleeding ◽

Case Control ◽

Pediatric Cardiac Surgery ◽

Nested Case Control ◽

Control Study

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FRI0438 Hospitalisation mortality and associated risk factors in patients with polymyositis and dermatomyositis: a retrospective case-control study

10.1136/annrheumdis-2018-eular.4447 ◽

2018 ◽

Author(s):

C. Wu ◽

Q. Wang ◽

L. HE ◽

E. Yang ◽

X. ZENG

Keyword(s):

Risk Factors ◽

Case Control Study ◽

Case Control ◽

Retrospective Case ◽

Associated Risk Factors ◽

Control Study

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Prehospital delay is an important risk factor for mortality in community-acquired bloodstream infection (CA-BSI): a matched case–control study

BMJ Open ◽

10.1136/bmjopen-2021-052582 ◽

2021 ◽

Vol 11 (11) ◽

pp. e052582

Author(s):

Martin Holmbom ◽

Maria Andersson ◽

Sören Berg ◽

Dan Eklund ◽

Pernilla Sobczynski ◽

...

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Bloodstream Infection ◽

Case Control Study ◽

Case Control ◽

Important Risk Factor ◽

Retrospective Case ◽

Prehospital Delay ◽

All Cause Mortality ◽

Control Study

ObjectivesThe aim of this study was to identify prehospital and early hospital risk factors associated with 30-day mortality in patients with blood culture-confirmed community-acquired bloodstream infection (CA-BSI) in Sweden.MethodsA retrospective case–control study of 1624 patients with CA-BSI (2015–2016), 195 non-survivors satisfying the inclusion criteria were matched 1:1 with 195 survivors for age, gender and microorganism. All forms of contact with a healthcare provider for symptoms of infection within 7 days prior CA-BSI episode were registered. Logistic regression was used to analyse risk factors for 30-day all-cause mortality.ResultsOf the 390 patients, 61% (115 non-survivors and 121 survivors) sought prehospital contact. The median time from first prehospital contact till hospital admission was 13 hours (6–52) for non-survivors and 7 hours (3–24) for survivors (p<0.01). Several risk factors for 30-day all-cause mortality were identified: prehospital delay OR=1.26 (95% CI: 1.07 to 1.47), p<0.01; severity of illness (Sequential Organ Failure Assessment score) OR=1.60 (95% CI: 1.40 to 1.83), p<0.01; comorbidity score (updated Charlson Index) OR=1.13 (95% CI: 1.05 to 1.22), p<0.01 and inadequate empirical antimicrobial therapy OR=3.92 (95% CI: 1.64 to 9.33), p<0.01. In a multivariable model, prehospital delay >24 hours from first contact remained an important risk factor for 30-day all-cause mortality due to CA-BSI OR=6.17 (95% CI: 2.19 to 17.38), p<0.01.ConclusionPrehospital delay and inappropriate empirical antibiotic therapy were found to be important risk factors for 30-day all-cause mortality associated with CA-BSI. Increased awareness and earlier detection of BSI in prehospital and early hospital care is critical for rapid initiation of adequate management and antibiotic treatment.

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