scholarly journals Prevalence and spatial distribution patterns of human echinococcosis at the township level in Sichuan Province, China

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Wei He ◽  
Li-Ying Wang ◽  
Wen-Jie Yu ◽  
Guang-Jia Zhang ◽  
Bo Zhong ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Spatial Autocorrelation ◽  
Prevention And Control ◽  
Control Strategies ◽  
Sichuan Province ◽  
Distribution Map ◽  
Distribution Features ◽  
And Control ◽  
Spatial Distribution Map ◽  
Human Echinococcosis

Abstract Background Echinococcosis is a global zoonotic parasitic disease caused by Echinococcus larvae. This disease is highly endemic in Sichuan Province, China. This study investigates the prevalence and spatial distribution characteristics of human echinococcosis at the township level in Sichuan Province, geared towards providing a future reference for the development of precise prevention and control strategies. Methods Human prevalence of echinococcosis was evaluated using the B-ultrasonography diagnostic method in Sichuan Province between 2016 and 2019. All data were collected, collated, and analyzed. A spatial distribution map was drawn to intuitively analyze the spatial distribution features. Eventually, the spatial autocorrelation was specified and local indicators of spatial association (LISA) clustering map was drawn to investigate the spatial aggregation of echinococcosis at the township level in Sichuan Province. Results The prevalence of echinococcosis in humans of Sichuan Province was 0.462%, among which the occurrence of cystic echinococcosis (CE) was 0.221%, while that of alveolar echinococcosis (AE) was 0.244%. Based on the results of the spatial distribution map, a predominance of echinococcosis in humans decreased gradually from west to east and from north to south. The Global Moran’s I index was 0.77 (Z = 32.07, P < 0.05), indicating that the prevalence of echinococcosis in humans was spatially clustered, exhibiting a significant spatial positive correlation. Further, the findings of local spatial autocorrelation analysis revealed that the “high–high” concentration areas were primarily located in some townships in the northwest of Sichuan Province. However, the “low–low” concentration areas were predominantly located in some townships in the southeast of Sichuan Province. Conclusions Our findings demonstrated that the prevalence of echinococcosis in humans of Sichuan Province follows a downward trend, suggesting that the current prevention and control work has achieved substantial outcomes. Nevertheless, the prevalence in humans at the township level is widely distributed and differs significantly, with a clear clustering in space. Therefore, precise prevention and control strategies should be formulated for clusters, specifically strengthening the “high–high” clusters at the township level. Graphic Abstract

scholarly journals Analysis of Spatial Distribution Characteristics of Human Echinococcosis at the Township Level in Sichuan Province, China

2021 ◽  
Author(s):  
Wei He ◽  
Wen-jie Yu ◽  
Guang-jia Zhang ◽  
Sha Liao ◽  
Qi Wang ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Prevention And Control ◽  
Control Strategies ◽  
Sichuan Province ◽  
Distribution Map ◽  
Trend Surface Analysis ◽  
Spatial Distribution Characteristics ◽  
And Control ◽  
Spatial Distribution Map ◽  
Human Echinococcosis

Abstract BackgroundEchinococcosis is a global zoonotic parasitic disease caused by the larvae of Echinococcus, which affects both humans and animals. In China, this disease is highly endemic in Sichuan Province. In this study, we investigated the prevalence and spatial distribution characteristics of human echinococcosis at the township level in Sichuan province, so as to provide a reference for the development of precise prevention and control strategies in the future.MethodsWe explored the prevalence of echinococcosis using the B-ultrasonography diagnostic method in Sichuan province between 2016 and 2019, where patients and transmission conditions had been identified in the past. All data were inputted using Epi-Info software, while SPSS software was used for statistical analysis. We then employed ArcGIS software to draw the spatial distribution map and perform trend surface analysis. Finally, Geoda software was used to analyze spatial autocorrelation and draw Lisa clustering map.ResultsA total of 2 542 135 people from 649 towns in 35 counties of Sichuan province were screened for echinococcosis, of which 11 743 echinococcosis patients were detected. The prevalence of echinococcosis in humans was 0.462%, among which the occurrence of cystic echinococcosis [CE] was 0.221%, while that of alveolar echinococcosis [AE] was 0.244%. We also observed that the predominance of echinococcosis in humans decreased gradually from west to east and from north to south based on the results of the spatial distribution map and trend surface analysis. The Global Moran's I index was 0.77 (Z = 32.07, P < 0.05), which indicated that the prevalence of echinococcosis in humans was spatially clustered, exhibiting a significant spatial positive correlation. Further, the findings of local spatial autocorrelation analysis revealed that the “high-high” concentration areas were primarily located in some townships in the northwest of Sichuan province. On the other hand, the “low-low” concentration areas were predominantly located in some townships in the southeast of Sichuan province. ConclusionOur findings demonstrated that the prevalence of echinococcosis in humans of Sichuan province is following a downward trend, implying that the current prevention and control work has achieved some substantial outcomes. However, the prevalence in humans at the township level is widely distributed and differs greatly, with a clear clustering in space. Therefore in the future, precise prevention and control strategies should be formulated for clusters, particularly strengthening the “high-high” clusters at the township level.

scholarly journals Prevalence and spatial distribution characteristics of human echinococcosis in China

2021 ◽  
Vol 15 (12) ◽  
pp. e0009996
Author(s):  
Li-Ying Wang ◽  
Min Qin ◽  
Ze-Hang Liu ◽  
Wei-Ping Wu ◽  
Ning Xiao ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Spatial Autocorrelation ◽  
Prevention And Control ◽  
Disease Prevalence ◽  
Tibet Plateau ◽  
Spatial Clusters ◽  
Autonomous Region ◽  
And Control ◽  
Qinghai Tibet Plateau ◽  
Human Echinococcosis

Background Echinococcosis is a zoonotic parasitic disease caused by larval stages of cestodes belonging to the genus Echinococcus. The infection affects people’s health and safety as well as agropastoral sector. In China, human echinococcosis is a major public health burden, especially in western China. Echinococcosis affects people health as well as agricultural and pastoral economy. Therefore, it is important to understand the prevalence status and spatial distribution of human echinococcosis in order to advance our knowledge of basic information for prevention and control measures reinforcement. Methods Report data on echinococcosis were collected in 370 counties in China in 2018 and were used to assess prevalence and spatial distribution. SPSS 21.0 was used to obtain the prevalence rate for CE and AE. For statistical analyses and mapping, all data were processed using SPSS 21.0 and ArcGIS 10.4, respectively. Chi-square test and Exact probability method were used to assess spatial autocorrelation and spatial clustering. Results A total of 47,278 cases of echinococcosis were recorded in 2018 in 370 endemic counties in China. The prevalence rate of human echinococcosis was 10.57 per 10,000. Analysis of the disease prevalence showed obvious spatial positive autocorrelation in globle spatial autocorrelation with two aggregation modes in local spatial autocorrelation, namely high-high and low-high aggregation areas. The high-high gathering areas were mainly concentrated in northern Tibet, western Qinghai, and Ganzi in the Tibetan Autonomous Region and in Sichuan. The low-high clusters were concentrated in Gamba, Kangma and Yadong counties of Tibet. In addition, spatial scanning analysis revealed two spatial clusters. One type of spatial clusters included 71 counties in Tibet Autonomous Region, 22 counties in Qinghai, 11 counties in Sichuan, three counties in Xinjiang Uygur Autonomous Region, two counties in Yunnan, and one county in Gansu. In the second category, six types of spatial clusters were observed in the counties of Xinjiang Uygur Autonomous Region, and the Qinghai, Gansu, and Sichuan Provinces. Conclusion This study showed a serious prevalence of human echinococcosis with obvious spatial aggregation of the disease prevalence in China. The Qinghai-Tibet Plateau is the "hot spot" area of human echinococcosis in China. Findings from this study indicate that there is an urgent need of joint strategies to strengthen efforts for the prevention and control of echinococcosis in China, especially in the Qinghai-Tibet Plateau.

scholarly journals The state of the leprosy epidemic in Yunnan, China 2011–2020: A spatial and spatiotemporal analysis, highlighting areas for intervention

2021 ◽  
Vol 15 (10) ◽  
pp. e0009783
Author(s):  
Xiaohua Chen ◽  
Tie-Jun Shui
Keyword(s):  
Public Health ◽  
Information System ◽  
Spatial Distribution ◽  
Spatial Autocorrelation ◽  
Prevention And Control ◽  
Public Health Problem ◽  
Distribution Analysis ◽  
Important Public Health Problem ◽  
And Control ◽  
Epidemiological Characteristics

Background Despite public health efforts to reduce the leprosy burden in Yunnan, China, leprosy remains an important public health problem in some specific areas. We analyzed the epidemiological characteristics and spatial distribution of leprosy in Yunnan, China, and provide data to guide disease prevention and control efforts. Methodology/principal findings The surveillance data of newly detected leprosy cases in Yunnan, China, during 2011–2020 were extracted from the LEPROSY MANAGEMANT INFORMATION SYSTEM IN CHINA (LEPMIS), and spatial distribution analysis, spatial autocorrelation analysis, and spatiotemporal scanning were performed with ArcGIS 10.6.1, GeoDa 1.8.8, and SaTScan 9.4.3 software, respectively. A total of 1907 newly detected leprosy cases were reported in Yunnan, China, during 2011–2020. The new case detection rate (NCDR) decreased from 0.62 in 2011 to 0.25 in 2020, with an annual incidence of 0.41/100,000 population. The proportions of multibacillary (MB) cases, cases in female patients, cases causing grade 2 physical disability (G2D), and cases in pediatric patients were 67.07%, 33.93%, 17.99%, and 2.83%, respectively. The number of counties with an incidence above 1/100,000 population decreased from 30 in 2011 to 8 in 2020. The Moran’s I of leprosy in Yunnan, China, during 2011–2020 ranged from 0.076 to 0.260, indicating the presence of spatial clusters. Local spatial autocorrelation (LSA) analysis showed that high-high cluster areas (hot spots) were mainly distributed in the southeastern, northern, and northwestern regions. Spatiotemporal scanning showed three clusters with high NCDRs. The probably primary clusters, occurring during January 1, 2011–December 31, 2015, covered 11 counties in the southeastern region (RR = 5.046515, LRR = 271.749664, P = 0.000). Conclusion The number of leprosy cases in Yunnan decreased overall, although some high-NCDR regions remained. Geographic information system (GIS) analysis coupled with spatial analysis indicated regions with leprosy clusters. Continuous leprosy prevention and control strategies in Yunnan Province should be established, and interventions in high-risk regions should be prioritized and further strengthened.

Effective infection prevention and control strategies in a large accredited psychiatric facility in Singapore

2020 ◽  
Author(s):  
Daniel Poremski ◽  
Sandra Henrietta Subner ◽  
Grace Lam Fong Kin ◽  
Raveen Dev Ram Dev ◽  
Mok Yee Ming ◽  
...  
Keyword(s):  
Mental Health ◽  
Prevention And Control ◽  
Infection Prevention ◽  
Control Strategies ◽  
Infection Prevention And Control ◽  
Psychiatric Facility ◽  
Essential Services ◽  
Community Transmission ◽  
And Control

The Institute of Mental Health in Singapore continues to attempt to prevent the introduction of COVID-19, despite community transmission. Essential services are maintained and quarantine measures are currently unnecessary. To help similar organizations, strategies are listed along three themes: sustaining essential services, preventing infection, and managing human and consumable resources.

High Rates of Streptococcus Agalactiae Clindamycin and Erythromycin Resistance in Vietnamese Pregnant Women

2021 ◽  
Author(s):  
Vu Du ◽  
Pham Thai Dung ◽  
Nguyen Linh Toan ◽  
Can Mao ◽  
Nguyen Thanh Bac ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Prevention And Control ◽  
Control Strategies ◽  
Geographic Area ◽  
Resistance Rate ◽  
Antibiotics Resistance ◽  
Erythromycin Resistance ◽  
Antimicrobial Susceptibility Pattern ◽  
And Control

Abstract Background Group B streptococcus (GBS) is a leading cause of morbidity and mortality in newborns. Maternal GBS colonization rates vary depending on geographic area, ethnic and social conditions worldwide. Many studies suggested the continuous surveillance of GBS to provide data to guide decision-making and planning prevention and control strategies. Here, we report the rate and the antimicrobial susceptibility pattern of GBS from Vietnamese pregnant women over 5 year period. Methods We worked with 3863 Vietnamese pregnant women at < 37 weeks of gestation at the National Hospital of Obstetrics and Gynecology, Hanoi, Vietnam from Jan 2016 to Dec 2020. The data were recorded and retrieved from the computerized laboratory database. GBS was identified according to the American Society for Microbiology’s guidelines. Antimicrobial susceptibility was tested by the VITEK 2 system or E-test strips. The results were calculated according to the MIC breakpoints recommended by the Clinical and Laboratory Standards Institute. Results The positivity for GBS was 8.02% (310/3863) and the highest resistance rate was to tetracycline 89.66% (234/261), followed by 76.23% (202/265) for erythromycin, 58.21% (156/268) for clindamycin. The multidrug-resistance rate was 59.19% (161/272), and 8.46% (23/272) of isolates were resistant to 6 to 7 of the 12 antibiotics. Resistance to clindamycin in the absence of erythromycin resistance was found in 6/272 (2.2%) samples. The resistance rate to clindamycin was significantly increased (p < 0.01) over the time study period. Nevertheless, all isolates were sensitive to penicillin, ampicillin, ceftriaxone, cefotaxime, quinupristin/dalfopristin, and vancomycin. Conclusion Our results indicate that penicillin and ampicillin are currently the drugs of choice for the prevention and treatment of GBS-related diseases for Vietnamese pregnant women. However, antibiotic resistance to erythromycin and clindamycin was high. Thus, it reinforces the need for continuous surveillance of GBS to provide data to guide planning prevention and control strategies.

scholarly journals Waterborne microorganisms and biofilms related to hospital infections: strategies for prevention and control in healthcare facilities

2015 ◽  
Vol 14 (1) ◽  
pp. 52-67 ◽  
Author(s):  
Raquel Vannucci Capelletti ◽  
Ângela Maria Moraes
Keyword(s):  
Nosocomial Infections ◽  
Distribution System ◽  
Prevention And Control ◽  
Water Distribution ◽  
Water Distribution System ◽  
Control Strategies ◽  
Hospital Infections ◽  
Healthcare Facilities ◽  
Microbiological Control ◽  
And Control

Water is the main stimulus for the development of microorganisms, and its flow has an important role in the spreading of contaminants. In hospitals, the water distribution system requires special attention since it can be a source of pathogens, including those in the form of biofilms often correlated with resistance of microorganisms to various treatments. In this paper, information relevant to cases of nosocomial infections involving water circuits as a source of contaminants is compiled, with emphasis on the importance of microbiological control strategies to prevent the installation, spreading and growth of microorganisms in hospitals. An overview of the worldwide situation is provided, with emphasis on Brazilian hospitals. Different approaches normally used to control the occurrence of nosocomial infections due to waterborne contaminants are analyzed, and the use of the polysaccharide chitosan for this specific application is briefly discussed.

scholarly journals Coordinated Management of COVID-19 Response: Lessons From Whole-of-Society and Whole-of-Health Strategies in Wuhan, China

2021 ◽  
Vol 9 ◽  
Author(s):  
Shanquan Chen ◽  
Pan Zhang ◽  
Yun Zhang ◽  
Hong Fung ◽  
Yong Han ◽  
...  
Keyword(s):  
Primary Care ◽  
Health Care ◽  
Health Care Delivery ◽  
Prevention And Control ◽  
Care Delivery ◽  
Control Strategies ◽  
Control Period ◽  
Targeted Prevention ◽  
First Line ◽  
And Control

Background: The outbreak of novel coronavirus disease 2019 (COVID-19) has been challenging globally following the scarcity of medical resources after a surge in demand. As the pandemic continues, the question remains on how to accomplish more with the existing resources and improve the efficiency of existing health care delivery systems worldwide. In this study, we reviewed the experience from Wuhan - the first city to experience a COVID-19 outbreak – that has presently shown evidence for efficient and effective local control of the epidemic.Material and Methods: We performed a retrospective qualitative study based on the document analysis of COVID-19-related materials and interviews with first-line people in Wuhan.Results: We extracted two themes (the evolution of Wuhan's prevention and control strategies on COVID-19 and corresponding effectiveness) and four sub-themes (routine prevention and control period, exploration period of targeted prevention and control strategies, mature period of prevention and control strategies, and recovery period). How Wuhan combatted COVID-19 through multi-tiered and multi-sectoral collaboration, overcoming its fragmented, hospital-centered, and treatment-dominated healthcare system, was illustrated and summarized.Conclusion: Four lessons for COVID-19 prevention and control were summarized: (a) Engage the communities and primary care not only in supporting but also in screening and controlling, and retain community and primary care as among the first line of COVID-19 defense; (b) Extend and stratify the existing health care delivery system; (c) Integrate person-centered integrated care into the whole coordination; and (d) Delink the revenue relationship between doctors and patients and safeguard the free-will of physicians when treating patients.

scholarly journals Trends of HIV/AIDS Highlighted the Progresses and Challenges in Prevention and Control From 1990 to 2019

2021 ◽  
Author(s):  
Zejin Ou ◽  
Huan He ◽  
Danfeng Yu ◽  
Yongzhi Li ◽  
Yuanhao Liang ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Control Strategies ◽  
Health Concern ◽  
Effective Prevention ◽  
Global Trends ◽  
Life Years ◽  
Disease Study ◽  
And Control ◽  
Increasing Trends ◽  
Hiv Aids

Abstract Background HIV/AIDS is a critical public health concern worldwide. This article aimed to demonstrate th trends of HIV/AIDS burden from 1990 to 2019.Methods Data was extracted from the Global Burden of Disease study (GBDs) 2019. Estimated annual percentage change (EAPC) and age-standardized rate (ASR) were estimated to quantify the trends at global, regional and national levels.Results During the period 1990-2004, the trend in incidence of HIV/AIDS was stable globally. Whereas the trends in prevalence, death and disability-adjusted life years (DALYs) had pronounced increasing trends, with the respective EAPCs were 7.47 (95%confidence interval [CI]: 5.84 to 9.12), 10.85(95%CI: 8.90 to 12.84), and 10.40(95%CI: 8.47 to 12.36). Meanwhile, the pronounced increasing trends were seen in low-resource settings, particularly that of death in Oceania and South Asia, in which the respective EAPCs were 44.76 (95%CI: 40.81 to 48.82) and 40.82 (95%CI: 34.31 to 47.64). However, the global trends in incidence, death and DALYs of HIV/AIDS pronouncedly decreased from 2005 to 2019, with the respective EAPCs were −2.68(95%CI: −2.82 to −2.53), −6.73(95%CI: −6.98 to −6.47) and −6.75(95%CI: −6.95 to −6.54). Whereas prevalence showed increasing trend (EAPC: 0.71, 95%CI: 0.54 to 0.87). Decreasing trends of HIV/AIDS were observed in most regions and countries, particularly that of death and DALYs in Burundi respectively were −15.28 (95%CI: −16.08 to −14.47) and −15.07 (95%CI: −15.79 to −14.33). Conclusions Decreasing trends of HIV/AIDS were observed worldwide over the past 15 years. However, HIV/AIDS remains one of the most critical causes of health loss worldwide, which emphasized the effective prevention and control strategies.

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