scholarly journals Ethnobotanical, phytochemistry, and pharmacological property of Waltheria Indica Linn

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
C Nirmala ◽  
M Sridevi
Keyword(s):  
Inflammatory Diseases ◽  
Biological Activities ◽  
Perennial Herb ◽  
Main Body ◽  
Biological Targets ◽  
Traditional Uses ◽  
Whole Plant ◽  
Anti Cancer ◽  
Microbial Infections ◽  
Anti Fungal

Abstract Background In modern therapeutics, various human pathological disturbances were treated with the plant-based products. Waltheria indica Linn, a perennial herb, was commonly used in traditional medicine worldwide against various ailments such as cough, dysentery, diarrhea, bladder disorder, hemoptysis, inflammations, neuralgia, wounds, and ulcers. Main body The shrub was majorly distributed in tropical, subtropical regions and exists in many distinct local forms. Both the crude extracts and purified compounds from the whole plant and its parts showed wide pharmacological properties like antioxidant, analgesic, sedative, anti-bacterial, anti-fungal, and anti-parasitic. The phytochemical profile and traditional usage highlight the potency of the plant in the treatment of microbial infections and inflammatory diseases. Yet, additional studies are required for the confirmations of its traditional uses against other diseases. More detailed understanding of anti-cataract, anti-diabetics, asthma, anemia, and anti-cancer mechanism has to be explored. Though many research articles on the proposed plant are available, there has been a rising concern in the therapeutic property, especially on the alkaloids and flavonoids from this plant for drug design. Conclusion This article aims in a systematic and updated review on distribution, botany, traditional uses, phytocompounds, and relevant biological activities from each part of the plant. The information was collected from databases like PubMed, ScienceDirect, Web of Science, Google Scholar, books, dissertation, and reports via academic libraries that included more than 100 articles published since 1937. This ethnopharmacological study of the plant may create new insight into drug discovery to develop important novel leads against various biological targets.

A review on phyto-pharmacology of Oxalis corniculata

2021 ◽  
Vol 24 ◽  
Author(s):  
Iqra Sarfraz ◽  
Azhar Rasul ◽  
Ghulam Hussain ◽  
Muhammad Ajmal Shah ◽  
Bushra Nageen ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Current Effort ◽  
Isolation And Characterization ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Fungal ◽  
Warm Temperate

: Oxalis corniculata (Oxalidaceae) is a small decumbent and delicate appearing medicinal herb flourishing in warm temperate and tropical domains such as Pakistan and India. Main bioactive chemical constituents of Oxalis plant include several alkaloids, flavonoids, terpenoids, cardiac glycosides, saponins, phlobatannins along with steroids. Due to its polyphenolic, glycosides and flavonoid profile, it is proved to be protective in numerous ailments and exhibit various biological activities such as anti-fungal, anti-cancer, anti-oxidant, anti-bacterial, anti-diabetic, and cardioprotective. Moreover, bioactive phytochemicals from this plant possess significant wound healing potential. Our current effort intends to emphasize on the immense significance of this plant species, which have not been the subject matter of clinical trials and effective pharmacological studies, even though its favored usage has been stated. This review proposes that Oxalis corniculata possess potential for the cure of various diseases, however, further researches on isolation and characterization of bioactive compounds along with pre-clinical trials are compulsory to figure out its pharmacological applications.

scholarly journals A REVIEW ON CHEMICAL CONSTITUENTS AND BIOLOGICAL ACTIVITIES OF THE GENUS PICRORHIZA (SCROPHULARIACE)

2021 ◽  
pp. 18-27
Author(s):  
ANJU BHATNAGAR
Keyword(s):  
Antioxidant Activities ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Iridoid Glycosides ◽  
Perennial Herb ◽  
Future Research ◽  
Scientific Databases ◽  
Plant Parts ◽  
Anti Cancer ◽  
Major Chemical

Picrorhiza (family Scrophulariace), commonly known as ‘kukti’ is a small perennial herb found in the Himalayan regions of China, Pakistan, India, Bhutan and Nepal at an altitude of 3000-5200 m. Different plant parts and its extract have traditionally been used as a remedy of various ailments such as fever, asthma, jaundice, anemia, abdominal pain, dysentery, cold, stomach problems. Picrorihza has been investigated for its chemical composition and biological activities by various researchers. The major chemical constituents found in this plant were iridoid glycosides, cucurbitacins (triterpenoids) glycosides, phenylethanoid glycosides and phenolics. The Picrorihza has various pharmacological properties, including hepto-protective, antimicrobial, anti-mutagenic, cardio-protective, anti-malarial, anti-diabetic, anti-cancer, anti-inflammatory, anti-ulcer, and neuroprotective and antioxidant activities. A thorough bibliographic investigation was carried out by analyzing worldwide scientific databases including Pub Med, Science Direct, Google Scholar and Wiley online as well as offline sources. The Present review is aimed to provide an updated overview of traditional uses, chemical constituents and biological activities of Picrorihza to explore its therapeutic potentials and to provide bases for future research.

Current Pharmaceutical Aspects of Synthetic Quinoline Derivatives

2020 ◽  
Vol 20 ◽  
Author(s):  
Rukhsana Tabassum ◽  
Muhammad Ashfaq ◽  
Hiroyuki Oku
Keyword(s):  
Fungal Infections ◽  
Biological Activities ◽  
Chemical Properties ◽  
New Drugs ◽  
Quinoline Derivatives ◽  
Wide Range ◽  
Anti Cancer ◽  
Anti Fungal ◽  
Physical And Chemical ◽  
And Chemical Properties

Abstract:: Quinoline derivatives are considered as broad spectrum pharmacological compounds that exhibit wide range of biological activities. Integration of quinoline moiety can improve its physical and chemical properties and also pharmacological behavior. Due to its wide range of pharmaceutical applications it is very popular compound to design new drugs for treatment of multiple diseases like cancer, dengue fever, malaria, tuberculosis, fungal infections, AIDS, Alzheimer’s disease and diabetes . In this review our major focus is to pay attention on biological activities of quinoline compounds in treatment of these diseases such as, anti-viral, anti-cancer, anti-malarial, anti-bacterial, anti-fungal, anti-tubercular and anti-diabetic.

scholarly journals The Health Benefits of Emodin, a Natural Anthraquinone Derived from Rhubarb—A Summary Update

2021 ◽  
Vol 22 (17) ◽  
pp. 9522
Author(s):  
Monika Stompor–Gorący
Keyword(s):  
Inflammatory Diseases ◽  
Biological Activities ◽  
Rheum Palmatum ◽  
Naturally Occurring ◽  
Wide Range ◽  
Microbial Infections ◽  
Potential Therapeutic Role ◽  
Long Time ◽  
Resistance To Chemotherapy

Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is a naturally occurring anthraquinone derivative found in roots and leaves of various plants, fungi and lichens. For a long time it has been used in traditional Chinese medicine as an active ingredient in herbs. Among other sources, it is isolated from the rhubarb Rheum palmatum or tuber fleece-flower Polygonam multiflorum. Emodin has a wide range of biological activities, including diuretic, antibacterial, antiulcer, anti-inflammatory, anticancer and antinociceptive. According to the most recent studies, emodin acts as an antimalarial and antiallergic agent, and can also reverse resistance to chemotherapy. In the present work the potential therapeutic role of emodin in treatment of inflammatory diseases, cancers and microbial infections is analysed.

scholarly journals A review on Lantana rhodesiensis Moldenke: traditional uses, phytochemical constituents and pharmacological activities

2017 ◽  
Vol 9 (1) ◽  
pp. 01 ◽  
Author(s):  
BANGOU Mindiédiba Jean ◽  
MEDA Roland Nâg-Tiero ◽  
KIENDREBEOGO Martin ◽  
NACOULMA Odile Germaine ◽  
ALMARAZ-ABARCA Norma
Keyword(s):  
Diabetes Mellitus ◽  
Chemical Composition ◽  
Biological Activities ◽  
Folk Medicine ◽  
Literature Survey ◽  
Parasitic Diseases ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Whole Plant ◽  
Phytochemical Constituents

<em>Lantana rhodesiensis</em> Moldenke an herbaceous, belonging to the Verbenaceae family is widely used in Africa folk medicine for the treatment of cancer, measles, malaria, smallpox, strength, coughs, fever, rheumatism, body pains, diabetes mellitus arrhythmia, parasitic diseases, arterial hypertension, old diarrhoeas. Many studies have been conducted on the chemical composition of the whole plant of <em>L. rhodesiensis</em> as well as biological activities.  The aim of the present review was to give a detailed literature survey on its traditional uses, phytochemistry and therapeutical properties of <em>L. rhodesiensis</em>.

Isolation, Synthesis and Medicinal Significance of Marine Pyridoacridine Alkaloids

2019 ◽  
Vol 23 (13) ◽  
pp. 1469-1495
Author(s):  
Saqlain Haider ◽  
Amar G. Chittiboyina ◽  
Ikhlas A. Khan
Keyword(s):  
Biological Activities ◽  
Marine Organisms ◽  
Present Review ◽  
Important Class ◽  
Anti Cancer ◽  
Anti Fungal ◽  
Pyridoacridine Alkaloids

Pyridoacridine alkaloids, distributed in marine organisms have emerged as an important class of compounds due to their uniqure chemical architecture, diversity and medicinal significance. These alkaloids are reported to exhibit a wide array of biological activities like anti-cancer, anti-bacterial, ant-viral, anti-fungal and anti-parasitic activities. The present review highlights the isolation, synthesis and medicinal significance of this important class of pyridoacridine alkaloids.

Electro-Catalytic process for the Synthesis of Organic Compounds and their Biological Applications

2020 ◽  
Vol 17 ◽  
Author(s):  
Zia Ul Haq Khan ◽  
Noor Samad Shah ◽  
Nawshad Muhammad ◽  
Arif Ullah Khan ◽  
Jibran Iqbal ◽  
...  
Keyword(s):  
Organic Compounds ◽  
Biological Activities ◽  
Active Species ◽  
High Yield ◽  
Synthesis Methods ◽  
Anti Cancer ◽  
Anti Fungal ◽  
Derivatives Of ◽  
Yield And Purity ◽  
Insight Into

Abstract: In fact, electrochemical method (EC) is a specific and eco-friendly technique with several advantages over common organic synthesis methods. During EC no as such external catalysts are required to initiate the reaction, the current potential in itself acts as a catalyst. Most of the inactive organic compounds can be converted to active species by EC method. This method results in the synthesis of compounds with high yield and purity. This method is also good to be applied for the synthesis of thermally sensitive organic compounds. Such synthesis has significant selectivity and reactivity which enable the synthesis of such compounds that are not feasible while using the conventional methods. This review provides insight into the utilization of EC method in the synthesis of organic compounds and their derivatives. Various prerequisites for such synthesis have been highlighted. The EC method application for preparation of derivatives of benzofuran, and benzoxazole, oxidation of N, N, N’, N’tetramethyl-1,4-phenylenediamine, 5-diethoxy-4-morpholinoaniline, organic compounds containing C=N, benzyl alcohol to benzaldehyde and tetratomic Thioethers have been discussed in detail. In addition, the electrochemical synthesis of biomedical important compounds has been presented. The compounds synthesized through EC methods shows potential antimicrobial activity. Deferent researchers work to study the potential biological application of organic compounds synthesized through EC process. The anti-cancer, anti-bacterial, anti-fungal and other important biological activities has been investigated.

scholarly journals A Review ofOenanthe javanica(Blume) DC. as Traditional Medicinal Plant and Its Therapeutic Potential

2019 ◽  
Vol 2019 ◽  
pp. 1-17 ◽  
Author(s):  
Chuan-li Lu ◽  
Xiu-fen Li
Keyword(s):  
Therapeutic Potential ◽  
Biological Activities ◽  
Flavonoid Glycosides ◽  
Inflammatory Conditions ◽  
Whole Plant ◽  
Anti Cancer ◽  
Toxicological Data ◽  
New Compounds ◽  
Phytochemical Studies ◽  
Ethanol Elimination

Oenanthe javanica, popularly known as water dropwort, has long been used in various ethnomedical systems in Asia, especially in China, Korean, and Japan, for treating various chronic and acute hepatitis, jaundice, alcohol hangovers, abdominal pain, and inflammatory conditions. The present review aims to provide a general report of the available literature on traditional uses, phytochemical, pharmacological, nutritional, and toxicological data related to theO. javanicaas a potential source of new compounds with biological activities. Considering phytochemical studies, coumarins, flavonoids and flavonoid glycosides, organic acids, and polyphenols were the main classes of compounds identified in the whole plant which were correlated with their biological activities such as hepatoprotective, anti-inflammatory, immune enhancement, ethanol elimination, antioxidant, antiviral, neuroprotective, anti-cancer, anticoagulant, anti-fatigue, hypoglycemic, cardiovascular protection, analgesic, and insecticidal activities.

scholarly journals Traditional uses, phytochemistry and pharmacology of Bauhinia racemosa Lam.: a comprehensive review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
S. Prabhu ◽  
S. Vijayakumar ◽  
Raju Ramasubbu ◽  
P. K. Praseetha ◽  
K. Karthikeyan ◽  
...  
Keyword(s):  
South India ◽  
Therapeutic Potential ◽  
Main Body ◽  
Asian Countries ◽  
Biological Mechanisms ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Pharmacological Studies ◽  
Microbial Infections ◽  
Ancient Times

Abstract Background Bauhinia racemosa is not familiarly known in Asian countries due to its limited existence and lack of medicinal information. It is commonly used as a medicine, ornamental plant, fence plant, and fodder for livestock since ancient times. It is also used as a landfill tree to avoid soil erosion of the forest. Main body In South India, people cultivate this plant in their premises in order to protect themselves from the effects of thunder. In this review, the various research prospects of this plant have been analyzed and are summarized. The aim of this review is to provide the traditional uses, phytochemicals and pharmacological activities of B. racemosa, and to highlight the current pharmacological developments of this medicinal plant. Conclusions The B. racemosa has immense therapeutic potential for treating diseases with both traditional and pharmacological applications. But many traditional uses of B. racemosa have not been validated by current investigations in the aspects of pharmaceutical. Until now, research on phyto-constituents from B. racemosa has not been done in an extensive way. Hence, the identified phytochemicals of B. racemosa should also be subjected to pharmacological studies to illuminate the biological mechanisms of these unreported secondary metabolites for the prevention of diseases or microbial infections and other health disorders of human and animal races.

scholarly journals Phytochemical Evaluation and Anti-Inflammatory Activity of Ethanolic Extract of Calotropis procera Leaves

2020 ◽  
Vol 11 (1) ◽  
pp. 1-6
Author(s):  
Naveed Aslam Dogar ◽  
Hamza Shahid ◽  
Hafiz Usama Shaukat ◽  
M. Abubakar Khan ◽  
Farooq Saleem
Keyword(s):  
Inflammatory Diseases ◽  
Biological Activities ◽  
Diclofenac Sodium ◽  
Ethanolic Extract ◽  
Inflammatory Activity ◽  
Calotropis Procera ◽  
Anti Cancer ◽  
Ethanolic Extraction ◽  
Anti Inflammatory

Background: Medicinal plants have been used since centuries to cure various diseases. There is a huge potential to investigate the medicinal impacts of different parts of plants. Roots, stem, leaves and fruits of Calotropis procera are known for their biological activities. Calotropis procera plant shows multiple pharmacological activities like anti-cancer, anti-microbial, antioxidant, anti-malarial, hepatoprotective and anti-diabetic activities. Objectives: The objective of the current research was ethanolic extraction of Calotropis procera leaves and to study the phytochemistry and anti-inflammatory activity. Methodology: In this effort, we used the extract of Calotropis procera leaves for detection of phytochemicals and anti-inflammatory activity in vitro by hypotonicity induced hemolysis on 2% HRBC suspension, using UV-Vis spectrophotometer. Results: Phytochemicals like alkaloids, terpenoids, and flavonoids were present in large amount while tannins, saponins, steroids and cardiac glycosides were in small amount, whereas phlobatannins and anthraquinone were not detected. The potential of the ethanolic extract of Calotropis procera leaves was compared with Diclofenac sodium (100μl/ml, 200μl/ml). The leaves extract of Calotropis procera (100, 200, 300, 400, 500μl/ml each) showed significant anti-inflammatory activity by hypotonicity induced hemolysis on 2% HRBC suspension. Conclusion: The Calotropis procera leaves have potential to cure inflammatory diseases and can be used as anti-inflammatory medicine and analgesic.

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