scholarly journals Clozapine use in old age psychiatry

2018 ◽  
Vol 24 (3) ◽  
pp. 204-211
Author(s):  
Amey Kirrane ◽  
Biswadeep Majumdar ◽  
Anna Richman

SUMMARYClozapine is one of the most effective drugs available to psychiatrists for treating psychosis. It is currently licensed for use in treatment-resistant schizophrenia and psychosis in Parkinson's disease, but its use in old age psychiatry is very uncommon. With the ageing population, and the increased incidence of psychosis in older patients, it is important to consider whether this is a drug that is not being used to its full advantage.LEARNING OBJECTIVES•Appreciate the differences in titration and monitoring of clozapine in older adults, compared with working-age adults•Consider the efficacy of clozapine in older people and its impact on mortality•Understand the side-effect profile of clozapine in older adultsDECLARATION OF INTERESTNone.


2018 ◽  
Vol 24 (3) ◽  
pp. 188-194 ◽  
Author(s):  
Oleksandr Khrypunov ◽  
Raheel Aziz ◽  
Ban Al-Kaissy ◽  
Ketan Jethwa ◽  
Verghese Joseph

SUMMARYOlder people with mental health problems are entitled to the same level and quality of care as younger people. Several factors continue to influence policy and delivery of older adults' mental health services in the UK. Following the introduction of the Equality Act 2010, there has been a drive to create an ‘ageless’ National Health Service. This has opened up the debate about whether such a service is best equipped to meet the specific needs of older adults. In this contribution we consider the concepts of ‘old age’ and ‘frailty’ and their clinical and service provision implications in psychiatry. The management of late-life depression and early-onset dementia, advance care planning and palliation in dementia are also considered.LEARNING OBJECTIVES•Appreciate how old age psychiatric services and the concept of ‘old age’ have evolved over time•Gain an understanding of issues at the interface between old age and general adult psychiatry and those specific to old age psychiatry•Gain an overview of procedures involved in transferring care between general adult and old age psychiatric services and the need for a separate old age psychiatry subspecialtyDECLARATION OF INTERESTNone.



2008 ◽  
Vol 25 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Fiona Campbell ◽  
Brian Parsons ◽  
Ruth Loane

AbstractObjective: There is a paucity of literature on the content of referral letters to psychiatric services and few relating specifically to referrals to a department of old age psychiatry. There has been a significant increase in referrals over the last five years to this service, which may reflect the ageing population and a greater awareness of the service. Our objective was to evaluate the quality and legibility of information received, clarity of reason for referral and details of pre-referral management.Methodology: The clinical records of the first 100 referrals in 2002 to this department were analysed. The referral letters were examined for the documentation of a number of demographic variables, reason for referral, interventions to date and level of urgency.Results: The clinical records of nine patients did not have an identifiable referral letter at the time of this analysis. Of the remaining 91 analysed, 59% were referred by their GP, 33% were inpatient liaison referrals and 8% from outpatient departments. In the majority, patients' details were given, however, only 30% included a phone number. Next-of-kin was mentioned in 29%. GP's name was included in 71% of referrals from OPD and 7% of liaison referrals. The level of urgency was stated in 19%. Whether a domiciliary or OPD visit would be more appropriate was stated in 22%. The reason for referral was clear in 75%, with 43% including some aspect of Mental State Examination, 7% had included a MMSE score, 1% mentioned level of suicide risk.Thirty-one per cent had pre-referral investigations and 45% had pre-referral treatment documented. The letters were clearly legible in 73%.Conclusion: The information in the referral letter in many cases was insufficient to prioritise and expedite appropriate assessment. It is planned to introduce a proforma referral form, specific to old age psychiatry, which would include the information which is required and which would, hopefully, lead to a more efficient service.



1999 ◽  
Vol 23 (3) ◽  
pp. 149-153 ◽  
Author(s):  
Jane Garner

Aims and MethodsThis report was prepared as the basis for wider consultation within the Old Age Faculty and the College. Some literature and practice is reviewed and practical suggestions made for the future in this area.ResultsAlthough older patients are less likely to be refused for psychological intervention attitudes are slowly changing.Clinical implicationsThe clinical implications of this development include a greater consideration of the unique emotional life of each of our patients and an improved understanding of our reluctance to engage in psychotherapeutic work with older people.



2018 ◽  
Vol 36 (4) ◽  
pp. 493-500 ◽  
Author(s):  
Abigail Moore ◽  
Caroline Croxson ◽  
Sara McKelvie ◽  
Dan Lasserson ◽  
Gail Hayward

Abstract Background The world has an ageing population. Infection is common in older adults; serious infection has a high mortality rate and is associated with unplanned admissions. In the UK, general practitioners (GPs) must identify which older patients require admission to hospital and provide appropriate care and support for those staying at home. Objectives To explore attitudes of UK GPs towards referring older patients with suspected infection to hospital, how they weigh up the decision to admit against the alternatives and how alternatives to admission could be made more effective. Methods. Qualitative study using semi-structured interviews. GPs were purposively sampled from across the UK to achieve maximum variation in terms of GP role, experience and practice population. Interview transcripts were coded and analysed using a modified framework approach. Results GPs’ key influences on decision making were grouped into patient, GP and system factors. Patient factors included clinical factors, social factors and shared decision making. GP factors included gut instinct, risk management and acknowledging an associated personal emotional burden. System factors involved weighing up the pressure on secondary care beds against increasing GP workload. GPs described that finding an alternative to admission could be more time consuming, complex to arrange or were restricted by lack of capacity. Conclusion GPs need to be empowered to make safe decisions about place of care for older adults with suspected infection. This may mean developing strategies to support decision making as well as improving the ease of access to, and capacity of, any alternatives to admission.



2015 ◽  
Vol 39 (2) ◽  
pp. 90-95 ◽  
Author(s):  
Claire Hilton

SummaryThe Equality Act 2010 made it unlawful to discriminate in the provision of services on the grounds of age. This legislation is open to interpretation, but it is affecting the way older people's services are defined and provided. Historical evidence indicates that, since the 1940s, apart from psychiatrists working in dedicated old age services, most were unenthusiastic about working with mentally unwell older people and unsupportive of those who chose to do so. A historical analysis might shed light on current dilemmas about ‘all age’ or ‘old age’ services and inform decision-making on future mental health services.



2015 ◽  
Vol 207 (5) ◽  
pp. 375-376 ◽  
Author(s):  
James P. Warner

SummaryOld age psychiatry services globally are under threat. The discipline enjoyed its heyday in the two decades bridging the millennium. More recently there has been a move to integrate old age services with those of working age adults, to create ‘ageless' services. Evidence is beginning to accumulate that this is a bad idea.



2018 ◽  
pp. 75-98 ◽  
Author(s):  
Karen Christensen

Title: The myth of the “Elder Boom”. Summary: The ageing population represents today one of the most central demographic challenges in many countries of the world, including Norway. In the public debate about the ageing population, the metaphor “Elder Boom” is increasingly being used. This article gives insight into the discussion in Norway and shows that the metaphor “Elder Boom” does not represent a constructive contribution to the ageing-population debate. The article provides arguments against two implications of the “Boom” metaphor: that ageing people are unwanted in society, and that older people represent a huge and increasing amount of welfare dependency. It shows how society over time has strived to control diseases (such as tuberculosis) in order to increase life expectancy. Society does, in fact, see old age as one of its major achievements, not as a problem as implied in the “Elder Boom” metaphor. The article also demonstrates how social policies implemented in the elderly-care sector in Norway have increasingly reduced services to elderly people while increasing allocation to younger people still of working age. By pointing out these changes in old age and elderly care over time, the article is a contribution to put an end to the myth of an “Elder Boom”. Overall, it contributes to the understanding of how this myth, bolstered by the Western world’s ideal of (welfare) independence, both stigmatizes and misconstrues elderly people’s dependency on the welfare state, which is in fact decreasing for various reasons.



2019 ◽  
Vol 25 (6) ◽  
pp. 377-386
Author(s):  
Azizah Attard ◽  
Andrew Iles ◽  
Stephen Attard ◽  
Nathan Atkinson ◽  
Anita Patel

SUMMARYClozapine, the antipsychotic of choice for treatment-resistant schizophrenia, has a number of side-effects, some of which are potentially life-threatening. Historically viewed as a relatively minor side-effect, there is increasing awareness of the potentially severe sequalae of constipation secondary to clozapine-induced gastrointestinal hypomotility (CIGH). These include ileus, intestinal obstruction, bowel ischaemia, gastrointestinal necrosis, toxic megacolon and death. CIGH is significantly more common than clozapine-induced blood dyscrasias and has a higher mortality rate. Although strict criteria must be followed to assertively monitor, detect and treat blood dyscrasias in patients taking clozapine, no such framework exists for CIGH. We recommend that prescribing guidelines, regulatory agencies and information from manufacturers should more clearly highlight the risks identified in the literature. Furthermore, we recommend that, in people taking clozapine, constipation should be prevented by prophylactic treatment with laxatives rather than treated only when clinically identified.LEARNING OBJECTIVES:After reading this article you will be able to: •understand the mechanism of gastrointestinal hypomotility in those taking clozapine•improve the monitoring of clozapine-induced constipation•understand prophylactic laxative treatment and the use of less commonly prescribed laxatives in patients who experience clozapine-induced constipation.



2006 ◽  
Vol 30 (11) ◽  
pp. 410-412 ◽  
Author(s):  
Raghupathy Paranthaman ◽  
Robert C. Baldwin

Aims and MethodThe aim of the survey was to assess the attitudes of specialists in old age psychiatry towards the use of clozapine in elderly patients. A postal questionnaire was sent to a random sample of 155 consultant old age psychiatrists in England.ResultsThe response rate was 87%. A majority of respondents felt that clozapine had a useful place in the treatment of elderly patients, although they expressed concerns about the lack of published data and about safety and practical difficulties in monitoring. Prescribers of clozapine (n=45) were significantly more positive about its role in treating older patients than those who had not used it.Clinical ImplicationsThe findings suggest that familiarity with and confidence in clozapine and practical difficulties in monitoring are important determinants of its use in older patients.



2005 ◽  
Vol 29 (9) ◽  
pp. 330-333 ◽  
Author(s):  
Adrian Treloar ◽  
Dimitrios Adamis

Aims and MethodIn a cross-sectional survey, we assessed the attitudes of older patients and their carers towards receiving copies of letters about them and the effects upon outcomes of sharing letters. We also studied the opinions of consultants on letter-sharing.ResultsFew old age psychiatrists shared letters with patients or carers, and many had concerns about this practice. In contrast, letters were considered ‘very welcome’ by 87% of patients and carers who received them, and 81% of those who did not would be ‘very pleased’ to receive them. Patients and carers who had received letters had significantly better knowledge of their care plan, whom to contact and ways of making contact with services.Clinical ImplicationsDespite concerns expressed by psychiatrists, our findings support the sharing of letters with patients and carers of patients with dementia in old age psychiatry services.



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