Neurocognitive function and psychological distress in young adults (YA) with cancer.

2016 ◽  
Vol 34 (3_suppl) ◽  
pp. 199-199
Author(s):  
Kim Edelstein ◽  
Norma Mammone D'Agostino ◽  
Gregory Russell Pond ◽  
Sylvie Aubin ◽  
Andrew Matthew ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Test Scores ◽  
Neurocognitive Function ◽  
Functional Brain Imaging ◽  
Self Report ◽  
Neurocognitive Performance ◽  
Neurocognitive Dysfunction ◽  
Somatic Distress ◽  
Neurocognitive Functions ◽  
Ambulatory Oncology

199 Background: Cancer treatment is associated with neurocognitive sequelae and changes in structural and functional brain imaging in older adults, even if they do not receive central nervous system directed therapy. Because the brain continues to develop into the 3rd decade of life, YA (age 18-39 yrs) may also be vulnerable to neurocognitive dysfunction. In YA, cancer disrupts acquisition of developmental milestones and is associated with psychological distress. This study aims to characterize neurocognitive functions and its relation to psychological distress in YA. Here we present baseline results of our longitudinal study. Methods: In this prospective, inception-cohort study, we recruited 3 groups of YA from ambulatory oncology clinics: YA with cancers (YAC; lymphoma, breast, gynecology, gastrointestinal, genitourinary, sarcoma) who required chemotherapy (YAC+, n = 55), YAC who do not require it (YAC-, n = 31), and healthy YA (HYA, n = 54). Participants completed a 2-hr battery of standardized neurocognitive tests and validated self-report questionnaires. YAC were assessed within 3 months of diagnosis, and YAC+prior to chemotherapy. Test scores were converted to age-corrected scaled scores and transformed to z-scores (mean 0, SD 1). A global neurocognitive function score and 6 domain scores were evaluated. Results: There were no group differences in neurocognitive domains (ANOVA, all p-values > .1), or in the number of impaired test scores (defined as z < -1). YAC+ reported greater symptoms of somatic distress (p = .001) and anxiety (p = .004) than both HYA and YAC-. Symptoms were unrelated to neurocognitive performance (ρ < .16 for all). However, each group had poorer memory compared to population norms (1-sample t-tests: YAC+ p = .007; YAC- p = .047; HYA p = .023). Conclusions: Prior to treatment, neurocognitive functions of YAC were not different from HYA, suggesting that cancer itself is not a neurocognitive risk factor in YA. It is important to use appropriate control groups, rather than relying on normative data for comparison. We continue to follow this cohort to document neurocognitive function and distress over time, and to identify risk factors that contribute to outcomes in YA.

Neurocognitive functions and psychological distress in young adults with cancer (YAC): A prospective, longitudinal study.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 10064-10064
Author(s):  
Kim Edelstein ◽  
Norma Mammone D'Agostino ◽  
Gregory Russell Pond ◽  
Petr Kavan ◽  
Abha A. Gupta ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Accelerated Aging ◽  
Group Differences ◽  
Neurocognitive Performance ◽  
Similar Time ◽  
Prospective Longitudinal Study ◽  
P Values ◽  
Neurocognitive Functions ◽  
Prospective Longitudinal ◽  
Over Time

10064 Background: Non-CNS cancer and treatments are associated with neurocognitive sequelae in older adults; whether YAC (age 18-39 yrs) are protected from these effects is unknown. In YAC, cancer interferes with education and occupational attainment and is associated with psychological distress. This prospective, inception-cohort study characterizes neurocognitive functions and psychological distress in YAC. Methods: YAC completed a 2-hr battery of standardized neurocognitive tests and questionnaires 1.7 ± 1 months after diagnosis prior to chemotherapy (mean ± SD, T1) and 8.2 ± 1.2 (T2) and 14.2 ± 1.6 (T3) months later. Healthy YA with no cancer history (HYA) were tested at similar time points. Tests were scored using published norms, transformed to T-scores, and grouped into neurocognitive domains. Results: YAC (n = 108; lymphoma, breast, gyne, GI, GU, sarcoma) were grouped according to whether they required chemotherapy (n = 70) or not (n = 38), and compared to 63 HYA. At baseline, there were no group differences in neurocognitive performance, number of impaired tests, or neurocognitive complaints (Kruskal Wallis, all p-values > .4). About 70% of each group completed assessments at T2 and T3. Mean performance improved over time (random effects models, all p-values < .01), but there were no group differences or interactions between group and time. There were also no differences in proportions of participants in each group whose test scores improved ( > 10 points) or declined ( < 10 points) from T1 to T2 or T3. Adjusting for psychological distress, fatigue, or neurocognitive complaints did not change these results, despite higher symptoms of somatic distress, anxiety and fatigue in YAC compared to healthy YA over time (all p-values < .03). Conclusions: Before chemotherapy and up to about 14 months later, YAC have elevated distress and fatigue, but do not demonstrate the cognitive decline reported in older cancer patients. Our findings are consistent with research suggesting that aging brains are more vulnerable to neurotoxic insult. Whether the effects of cancer treatment emerge later in YAC, placing them at risk for accelerated aging as reported in older patients, remains to be examined.

Internet Navigation Skills for Financial Management: Associations with Age, Neurocognitive Performance, and Functional Capacity

2020 ◽  
Author(s):  
Samina Rahman ◽  
Victoria Kordovski ◽  
Savanna Tierney ◽  
Steven Paul Woods
Keyword(s):  
Older Adults ◽  
Functional Capacity ◽  
Financial Management ◽  
Internet Banking ◽  
Online Banking ◽  
Neurocognitive Performance ◽  
Younger Adults ◽  
Neurocognitive Functions ◽  
Age Related ◽  
Use Factors

Objective: Online banking is becoming increasingly common among older adults, whomay experience difficulties effectively navigating this instrumental technology. Thisstudy examined age effects on a performance-based Internet banking task and itsassociation with neurocognitive ability and functional capacity in older and youngeradults. Method: Thirty-five older adults and 50 younger adults completed anexperimenter-controlled online banking measure in which they independentlyperformed a series of naturalistic financial tasks (e.g., account transfers, bill paying).Participants also completed a standardized battery of neuropsychological tests andmeasures of functional capacity. Results: Older adults were markedly slower and lessaccurate in completing the Internet-based banking task, which was not confounded byother demographic, mood, or computer use factors. Higher scores on measures ofneurocognition and financial functional capacity were both strongly associated withhigher Internet-based banking task accuracy scores and quicker completion times inthe older, but not the younger adults. Conclusions: Findings suggest that older adultsexperience difficultly quickly and accurately navigating online banking platforms, whichmay be partly related to age-related declines in neurocognitive functions and basicfinancial capacity. Future studies might examine whether neurocognitive approaches toremediation and compensation can be used to improve online banking capacity inolder adults.

scholarly journals Psychological Distress and Post-Traumatic Symptomatology among Dental Healthcare Workers in Russia: Results of a Pilot Study

2021 ◽  
Vol 18 (2) ◽  
pp. 708 ◽  
Author(s):  
Maria Sarapultseva ◽  
Alena Zolotareva ◽  
Igor Kritsky ◽  
Natal’ya Nasretdinova ◽  
Alexey Sarapultsev
Keyword(s):  
Psychological Distress ◽  
Healthcare Workers ◽  
Mental Health Problems ◽  
Clinical Symptoms ◽  
Stress Disorders ◽  
Self Report ◽  
Ptsd Symptoms ◽  
Event Scale ◽  
Post Traumatic ◽  
The Impact

The spread of SARS-CoV-2 infection has increased the risk of mental health problems, including post-traumatic stress disorders (PTSD), and healthcare workers (HCWs) are at greater risk than other occupational groups. This observational cross-sectional study aimed to explore the symptoms of depression, anxiety, and PTSD among dental HCWs in Russia during the coronavirus disease 2019 (COVID-19) pandemic. The survey was carried out among 128 dental HCWs from three dental clinics of Ekaterinburg, Russia. The mean age of the sample was 38.6 years. Depression, anxiety, and stress were assessed using the Depression Anxiety and Stress Scale-21 (DASS-21); PTSD was assessed using the PTSD Symptom Scale-Self-Report (PSS-SR); subjective distress was assessed using the Impact of Event Scale-Revised (IES-R). The results indicated that 20.3–24.2% HCWs had mild to extremely severe symptoms of psychological distress, and 7.1–29.7% had clinical symptoms of PTSD. No differences between females and males were revealed. HCWs working directly with patients had significantly higher levels of PTSD symptoms and the risk of PTSD development compared to those working indirectly, whereas older HCWs had significantly higher levels of both psychological distress and PTSD symptoms compared to younger HCWs. Thus, dental HCWs are at high risk for psychological distress and PTSD symptoms during the COVID-19 pandemic.

scholarly journals Cross-cultural adaptation and psychometric properties of the Kessler Distress Scale (K10): an application of the rating scale model

2021 ◽  
Vol 34 (1) ◽  
Author(s):  
Evandro Morais Peixoto ◽  
Daniela Sacramento Zanini ◽  
Josemberg Moura de Andrade
Keyword(s):  
Psychological Distress ◽  
Psychometric Properties ◽  
Rating Scale ◽  
Self Report ◽  
Clinical Population ◽  
Scale Model ◽  
General Factor ◽  
Measurement Models ◽  
Distress Scale ◽  
Rating Scale Model

Abstract Background The Kessler Distress Scale (K10) is a self-report scale for the assessment of non-specific psychological distress in the general and clinical population. Because of its ease of application and good psychometric properties, the K10 has been adapted to several cultures. The present study seeks to adapt the K10 to Brazilian Portuguese and estimate its validity evidence and reliability. Methods A total of 1914 individuals from the general population participated in the study (age = 34.88, SD = 13.61, 77.7% female). The adjustment indices were compared among three different measurement models proposed for the K10 through confirmatory factor analysis (CFA). The items’ properties were analyzed by Andrich’s Rating Scale Model (RSM). Furthermore, evidence based on relations to other variables (depression, stress, anxiety, positive and negative affects, and satisfaction with life) was estimated. Results CFA indicated the adequacy of the bifactor model (CFI= 0.985; TLI= 0.973; SMR= 0.019; RMSEA= 0.050), composed of two specific factors (depression and anxiety) and one general factor (psychological distress), corresponding to the theoretical hypothesis. Additionally, it was observed multiple-group invariance by gender and age range. The RSM provided an understanding of the organization of the continuum represented by the psychological distress construct (items difficulty), which varied from −0.89 to 1.00; good adjustment indexes; infit between 0.67 and 1.32; outfit between 0.68 and 1.34; and desirable reliability, α= 0.87. Lastly, theoretically coherent associations with the external variables were observed. Conclusions It is concluded that the Brazilian version of the K10 is a suitable measure of psychological distress for the Brazilian population.

scholarly journals The relationship of insight with psychopathological dimensions in patients with schizophrenia

2021 ◽  
Vol 12 (2) ◽  
pp. 204380872110199
Author(s):  
Si-Sheng Huang ◽  
Cheng-Chen Chang
Keyword(s):  
Medical Center ◽  
Self Report ◽  
Psychiatric Ward ◽  
Neurocognitive Functions ◽  
Bivariate Correlation ◽  
Syndrome Scale ◽  
Acute Psychiatric Ward ◽  
Negative Syndrome ◽  
Relationship Of ◽  
The Relationship

Impaired insight in patients with schizophrenia results in less satisfactory clinical outcomes. This study was conducted to investigate the relationship between insight and individual psychopathological dimensions in inpatients with schizophrenia using a self-report questionnaire. In this study, 90 patients with schizophrenia aged 18–75 years admitted in the acute psychiatric ward of a medical center in Taiwan were enrolled. Patient insight was measured using the Self-Appraisal of Illness Questionnaire (SAIQ), and psychopathological dimensions were measured using the Positive and Negative Syndrome Scale (PANSS) and its five-factor structure model. A higher SAIQ score indicates greater insight. In bivariate correlation analyses, statistically significant correlations were observed between age, single marital status, educational level, and positive, excited, and depressed symptom factor of the PANSS and SAIQ score. In regression analyses, age and excited and depressed symptom factors were significantly associated with SAIQ score. No significant association was observed between insight and neurocognitive functions. Considering demographic characteristics, psychopathology, and neurocognition, in the acute phase of schizophrenia, younger patients with less severe excited symptoms and more severe depressive symptoms had greater insight.

scholarly journals ‘Should I Stay, or Should I Go?’ Psychological Distress Predicts Career Change Ideation among Intensive Care Staff in Lithuania and the UK Amid COVID-19 Pandemic

2021 ◽  
Vol 18 (5) ◽  
pp. 2660
Author(s):  
Ieva Norkiene ◽  
Lina Jovarauskaite ◽  
Monika Kvedaraite ◽  
Encarl Uppal ◽  
Mandeep Kaur Phull ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Healthcare Professionals ◽  
Psychosocial Support ◽  
Career Change ◽  
Well Being ◽  
Self Report ◽  
Care Staff ◽  
Psychological Well Being ◽  
The United Kingdom ◽  
The Uk

The COVID-19 pandemic had a significant effect on healthcare globally. Additional pressure created by coronavirus adversely affected the mental health and psychological well-being of healthcare workers, leading many to question their desire and willingness to continue working in healthcare. This study aimed to identify predictors for career change ideation among healthcare professionals in two countries; Lithuania and the United Kingdom amid the coronavirus pandemic. In total, 610 healthcare professionals from Lithuania and the UK (285 and 325, respectively) participated in a survey from May to August 2020. Psychological distress and psychological well-being were measured using the self-report scales “DASS-21” and “WHO-5”. Almost half of the sample (49.2%), 59.6% and 40.0% in Lithuanian and the UK, respectively, exhibited career change ideation, the country effect was significant (AOR = 2.21, p < 0.001). Stronger ideation to leave healthcare was predicted by higher levels of depression (AOR = 1.10, p = 0.005), stress (AOR = 1.10, p = 0.007), anxiety surrounding inadequate personal protective equipment (AOR = 2.27, p = 0.009), and lower psychological well-being scores (AOR = 1.10, p = 0.007). We conclude that psychosocial support must be provided for healthcare professionals to prevent burnout and loss of staff amid the pandemic.

Femininity, Bulimia, and Distress in College Women

1998 ◽  
Vol 83 (1) ◽  
pp. 355-363 ◽  
Author(s):  
Elizabeth W. Brazelton ◽  
Katherine S. Greene ◽  
Malcolm Gynther ◽  
Jennifer O'Mell
Keyword(s):  
Psychological Distress ◽  
College Women ◽  
Multiple Regression ◽  
Social Connectedness ◽  
Significant Contribution ◽  
Cognitive Distortions ◽  
Cognitive Distortion ◽  
Self Report

This study investigated differences in the scores on perceived Distress and Bulimia among college women with varying scores on the Behavioral Self-report of Femininity. Distress was assessed using The Psychological Distress Inventory and Bulimia was measured using the Bulimia Cognitive Distortions Scale. Women who reported low numbers of stereotypic feminine behaviors scored lower on the Bulimia Cognitive Distortions Scale than women reporting moderate to high numbers of stereotypic feminine behaviors. Distress scores were not significantly different between women scoring high and low on Bulimic Cognitive Distortions, and Bulimic Cognitive Distortion scores did not vary as a function of scores on Distress and Femininity. A multiple regression indicated that one factor of the Behavioral Self-report of Femininity, Social Connectedness, made a significant contribution to the prediction of Bulimia scores.

scholarly journals Cyberbullying victimisation and internalising and externalising problems among adolescents: the moderating role of parent–child relationship and child's sex

2018 ◽  
Vol 29 ◽  
Author(s):  
H. Sampasa-Kanyinga ◽  
K. Lalande ◽  
I. Colman
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Psychological Distress ◽  
Poor Mental Health ◽  
Self Report ◽  
Parent Child Relationship ◽  
Child Relationship ◽  
Externalising Problems ◽  
Bullying Victimisation ◽  
Parent Child

Abstract Aims Previous research has found links between cyberbullying victimisation and internalising and externalising problems among adolescents. However, little is known about the factors that might moderate these relationships. Thus, the present study examined the relationships between cyberbullying victimisation and psychological distress, suicidality, self-rated poor mental health and substance use among adolescents, and tested whether parent–child relationship and child's sex would moderate these relationships. Methods Self-report data on experiences of cyberbullying victimisation, self-rated poor mental health, psychological distress, suicidality and substance use were derived from the 2013 Ontario Student Drug Use and Health Survey, a province-wide school-based survey of students in grades 7 through 12 aged 11–20 years (N = 5478). Logistic regression models adjusted for age, sex, ethnicity, subjective socioeconomic status and involvement in physical fighting, bullying victimisation and perpetration at school. Results Cyberbullying victimisation was associated with self-rated poor mental health (adjusted odds ratio (OR) 2.15; 95% confidence interval (CI) 1.64–2.81), psychological distress (OR 2.41; 95% CI 1.90–3.06), suicidal ideation (OR 2.38; 95% CI 1.83–3.08) and attempts (OR 2.07; 95% CI 1.27–3.38), smoking tobacco cigarette (OR 1.96; 95% CI 1.45–2.65), cannabis use (OR 1.82; 95% CI 1.32–2.51), and binge drinking (OR 1.44; 95% CI 1.03–2.02). The association between cyberbullying victimisation and psychological distress was modified by parent–child relationship and child's sex (three-way interaction term p < 0.05). The association between cyberbullying victimisation and psychological distress was much stronger among boys who have a negative relationship with their parents. Conclusions Findings suggest that cyberbullying victimisation is strongly associated with psychological distress in most adolescents with the exception of males who get along well with their parents. Further research using a longitudinal design is necessary to disentangle the interrelationship among child's sex, parent–child relationship, cyberbullying victimisation and mental health outcomes among adolescents in order to improve ongoing mental health prevention efforts.

Gender Differences in Grief Reactions following the Death of a Parent

2006 ◽  
Vol 52 (4) ◽  
pp. 323-337 ◽  
Author(s):  
Elizabeth Lawrence ◽  
Elizabeth L. Jeglic ◽  
Laura T. Matthews ◽  
Carolyn M. Pepper
Keyword(s):  
Gender Differences ◽  
Psychological Distress ◽  
Psychological Functioning ◽  
Clinical Importance ◽  
Self Report ◽  
Future Research ◽  
Symptoms Of Depression ◽  
Death Of A Parent ◽  
And Coping ◽  
Grief Reactions

This study examined gender differences in psychological functioning in a sample of college students who lost a parent to death. Male and female students ( n = 65) who had a parent that had died were asked to complete a series of self report questionnaires to assess psychological distress, feelings of grief and bereavement, and coping strategies. Overall, no gender differences were found between bereaved students on measures of psychological distress. However an avoidant coping style was related to symptoms of depression in females, but not in males. Students who lost a mother were more likely to report symptoms of depression, hopelessness, and suicidal ideation as compared to students who lost a father. Future research implications and the clinical importance of these findings are discussed.

Sign in / Sign up

Export Citation Format

Share Document