Outcomes of Microneurovascular Facial Reanimation Using Masseteric Innervation in Patients With Long-Standing Facial Palsy Resulting From Cured Brainstem Lesions

Neurosurgery ◽  
2010 ◽  
Vol 67 (3) ◽  
pp. 663-674 ◽  
Author(s):  
Kartik G. Krishnan ◽  
Gabriele Schackert ◽  
Volker Seifert

Abstract BACKGROUND The functions of the human face are not only of esthetic significance but also extend into metaphoric nuances of psychology. The loss of function of one or both facial nerves has a remarkable impact on patients' lives. OBJECTIVE To retrospectively analyze the functional outcomes of microneurovascular facial reanimation using masseteric innervation. METHODS Seventeen patients with irreparable facial paralysis resulting from benign lesions involving the facial nuclei (n = 14) or Möbius syndrome (n = 3) were treated with free muscle flaps for oral commissural reanimation using ipsilateral masseteric innervation and using temporalis muscle transfer for eyelid reanimation. Results were analyzed by the absolute commissural excursion and commissural excursion index and by a patient self-evaluation score. Presence of synkinesis was documented. Follow-up ranged from 8 to 48 months (mean, 26.4 months). RESULTS Normalization of the commissural excursion index was observed in 8 of 17 patients (47%), an improvement was seen in 7 of 17 (41%), and failure was observed in 2 of 17 (12%). The individual dynamics of absolute commissural excursion and commissural excursion index changes are presented. A natural smiling response was observed in 10 of 17 patients (59%) but not in the remaining 7 (41%). This response reflected the patient's ability to relay the natural emotion of smiling through the masseteric nerve. Patients' self-evaluation scores were a level higher than objective indices. CONCLUSIONS Innervation of free muscle flaps with the masseteric nerve for oral commissure reanimation might play an important role in patients with lesions of the facial nuclei (as in Möbius syndrome). Synkinesis persists for long periods after surgery. However, most of the patients learned to express their emotions by overcoming this phenomenon. Despite hypercorrection or inadequate correction, patients evaluated themselves favorably.

Author(s):  
Peggy J. Miller ◽  
Grace E. Cho

Chapter 12, “Commentary: Personalization,” discusses the process of personalization, based on the portraits presented in Chapters 8–11. Personalization is not just a matter of individual variation; it is a form of active engagement through which individuals endow imaginaries with personal meanings and refract the imaginary through their own experiences. The portraits illustrate how the social imaginary of childrearing and self-esteem entered into dialogue with the complex realities of people’s lives. Parents’ ability to implement their childrearing goals was constrained and enabled by their past experiences and by socioeconomic conditions. The individual children were developing different strategies of self-evaluation, different expectations about how affirming the world would be, and different self-defining interests, and their self-making varied, depending on the situation. Some children received diagnoses of low self-esteem as early as preschool.


Genes ◽  
2020 ◽  
Vol 11 (11) ◽  
pp. 1240
Author(s):  
Agnieszka Rafalska ◽  
Anna M. Tracewska ◽  
Anna Turno-Kręcicka ◽  
Milena J. Szafraniec ◽  
Marta Misiuk-Hojło

CEP290 is a ciliary gene frequently mutated in ciliopathies, resulting in a broad range of phenotypes, ranging from isolated inherited retinal disorders (IRDs) to severe or lethal syndromes with multisystemic involvement. Patients with non-syndromic CEP290-linked disease experience profound and early vision loss due to cone-rod dystrophy, as in Leber congenital amaurosis. In this case report, we describe two novel loss-of-function heterozygous alterations in the CEP290 gene, discovered in a patient suffering from retinitis pigmentosa using massive parallel sequencing of a molecular inversion probes library constructed for 108 genes involved in IRDs. A milder phenotype than expected was found in the individual, which serves to prove that some CEP290-associated disorders may display preserved cone function.


Author(s):  
Matthew J. Urban ◽  
Michael Eggerstedt ◽  
Eleni Varelas ◽  
Madeline J. Epsten ◽  
Adam J. Beer ◽  
...  

2021 ◽  
Vol 9 (1) ◽  
pp. 101-127
Author(s):  
Joyce Marie T. Sumatra

Emotional Intelligence (EI) is the ability to appraise and express one’s emotions, appraise and recognize the emotion of others, regulate one’s emotion, and use the emotion to facilitate one’s performance. Job performance of teaching employees refers to the instructional skills, personal & social qualities, educational leadership, and executive ability of the teachers, which is evaluated by the employees and their respective department/office head. This study was designed to examine the correlation between EI and job performance of the teaching employees. The study utilized a descriptive quantitative survey method using standardized questionnaires in gathering the data. The study respondents comprised 111 full-time teaching regular employees in different departments of the University of Bohol. This study used the Wong and Law Emotional Intelligence Scale with overall reliability between 0.77-0.91, which measured the EI of the respondents. Results displayed a significant positive correlation between EI and job performance. This study implies that as EI increases, the job performance of the teaching employees also increases. Moreover, the job performance between self-evaluation and office head evaluation does not significantly differ. This research indicates that the evaluation scores have no difference in how the teaching employees rated themselves and their respective office/department heads.


2021 ◽  
Vol 7 (5) ◽  
pp. 1428-1434
Author(s):  
Yang Gao ◽  
Liang Li ◽  
Qingyun Peng ◽  
Yahui Yang ◽  
Huifen Xu ◽  
...  

to analyze the effect of peppermint water spray combined with external application of cucumber slice or lip balm and conventional dipping in patients with dry mouth in intensive care unit (ICU). Methods: 120 patients with secondary xerostomia in our hospital from January 2018 to December 2019 were selected as the subjects. According to the different treatment methods, the patients were divided into A group (Peppermint water spray combined with cucumber slices for external application), group B (Peppermint water spray combined with lip gloss smear), group C (cotton swab dipped in normal saline), 40 cases in each group, and the saliva secretion and dry mouth before and after intervention in three groups were compared between the three groups. The degree of self-evaluation score and the evaluation of throat comfort and satisfaction after intervention. Results: after the intervention, the self-evaluation scores of salivary secretion and dry mouth degree of patients in group A and B were significantly higher than those before the intervention (P < 0.01), the self-evaluation scores of salivary secretion and dry mouth degree of patients in group A were significantly higher than those in group B and C (P < 0.01), and the self-evaluation scores of salivary secretion and dry mouth degree of patients in group B were significantly higher than those in group C (P < 0.01). After intervention, the total effective rate of improvement of throat comfort in group A was 87.50%, which was significantly higher than 40.00% in group B and 0.00% in group C (P < 0.01). The total effective rate of improvement of throat comfort in group B was significantly higher than that in group C (P < 0.01). 97.50% of the patients in group A were significantly higher than 72.50% in group B and 2.50% in group C (P < 0.01), and the patients in group B were significantly higher than those in group C (P < 0.01). Conclusion: homemade peppermint water spray combined with external application of cucumber spray can effectively improve the symptoms of dry mouth and throat discomfort in patients with ICU, improve their satisfaction with treatment, and is conducive to the recovery of patients’ diseases, which is worthy of clinical promotion and application.


Facial Palsy ◽  
2021 ◽  
pp. 189-195
Author(s):  
Alexander Cardenas-Mejia ◽  
Jose E. Telich-Tarriba ◽  
Alexandro Aguilera-Salgado

2008 ◽  
Vol 35 (11) ◽  
pp. 1091 ◽  
Author(s):  
Lei Wang ◽  
Neil A. Smith ◽  
Lan Zhang ◽  
Elizabeth S. Dennis ◽  
Peter M. Waterhouse ◽  
...  

RNA-dependent RNA polymerase (RDR) activities were readily detected in extracts from cauliflower and broccoli florets, Arabidopsis thaliana (L.) Heynh callus tissue and broccoli nuclei. The synthesis of complementary RNA (cRNA) was independent of a RNA primer, whether or not the primer contained a 3′ terminal 2′-O-methyl group or was phosphorylated at the 5′ terminus. cRNA synthesis in plant extracts was not affected by loss-of-function mutations in the DICER-LIKE (DCL) proteins DCL2, DCL3, and DCL4, indicating that RDRs function independently of these DCL proteins. A loss-of-function mutation in RDR1, RDR2 or RDR6 did not significantly reduce the amount of cRNA synthesis. This indicates that these RDRs did not account for the bulk RDR activities in plant extracts, and suggest that either the individual RDRs each contribute a fraction of polymerase activity or another RDR(s) is predominant in the plant extract.


2018 ◽  
Vol 26 (3) ◽  
pp. 398-414 ◽  
Author(s):  
Zoltán Krajcsák

Purpose The purpose of this study is to describe the relationship between organizational commitment and organizational culture with self-evaluation as a mediator variable. The theoretical framework evaluates the culture–commitment relationship based on the characteristics of the individual and underpins explanations of commitment patterns assigned to certain dimensions of organizational culture. Design/methodology/approach The study uses a purely theoretical approach, an instrument of which is abstract model creation. Findings The individual factors that reinforce deliberate, affective and professional commitment are the hierarchy culture; self-esteem; and self-efficacy, respectively. Research limitations/implications The existence of the relationship between the four factors of self-evaluation and the dimensions of the competing values framework (CVF) can be justified by secondary data analysis, although the direction of the causality is still questionable. Practical application of the theoretical model should be supported by empirical analyses in the future. Originality/value Research activity in organizational psychology is still mapping the elusive relationship between organizational culture and organizational commitment. In terms of organizational culture, the model is based upon the CVF and uses the five-dimension model of employee commitment instead of the mainstream concept of organizational commitment. This theoretical framework is suitable for evaluating the relationship between organizational culture and commitment when considering the individual features of the employee and supports the explanation of commitment patterns assigned to cultural dimensions.


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