Symptoms of Depression are Common in Patients With Idiopathic Normal Pressure Hydrocephalus

ABSTRACT BACKGROUND: If patients with idiopathic normal pressure hydrocephalus (INPH) also have depression, this could have important clinical ramifications in assessment and management of their cognitive function and response to shunting. In many dementias, depression is overrepresented, but the prevalence of depression in shunted patients with INPH is unknown. OBJECTIVE: The objective of this case-control study was to assess the prevalence of symptoms of depression in shunted INPH patients compared with population-based controls. METHODS: INPH patients consecutively shunted from 2008 to 2010 in Sweden were analyzed. Patients remaining after inclusion (within 60-85 years and not having dementia, ie, mini-mental state examination ≥23) had a standardized visit to their healthcare provider and answered an extensive questionnaire. Age- and sex-matched population-based controls underwent the same procedure. Symptoms of depression were assessed using the Geriatric Depression Scale 15 (suspected depression defined as ≥5 points, suspected severe depression as ≥12 points). This study is part of the INPH-CRasH study. RESULTS: One hundred seventy-six INPH patients and 368 controls participated. After adjustment for age, sex, cerebrovascular disease, and systolic and diastolic blood pressure, patients had a higher mean depression score (patients: 4.9 ± 3.7 SD, controls: 1.9 ± 2.3 SD; OR 1.4, 95% CI 1.3-1.6, P < .001), more patients had suspected depression (46% vs 13%, OR 6.4, 95% CI 3.8-10.9, P < .001), and more patients had suspected severe depression (7.3% vs 0.6%, OR 14.4, 95% CI 3.0-68.6, P < .005). CONCLUSION: Symptoms of depression are overrepresented in INPH patients compared with the population, despite treatment with a shunt. Screening for depression should be done in the evaluation of INPH patients in order to find and treat a coexisting depression.

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Prevalence of depression in residents of gerontology centre in Sarajevo

Journal of Health Sciences ◽

10.17532/jhsci.2012.62 ◽

2012 ◽

Vol 2 (1) ◽

pp. 40-45

Author(s):

Jasmina Mahmutović ◽

Aida Rudić ◽

Fatima Jusupović ◽

Arzija Pašalić ◽

Refet Gojak

Keyword(s):

Medical Records ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Severe Depression ◽

Health State ◽

Mild Depression ◽

Cross Sectional ◽

Third Age ◽

Prevalence Of Depression ◽

Third Age Of Life

Introduction: Depressive disorder, as a major problem of public health, takes high fourth place in its prevalence in general population, and is considered to be the second most frequent health problem of femalepopulation. Depression is the most frequent mental problem of persons in their third age of life. The aim of this study is to evaluate prevalence of depression and establish the ratio between the current number ofdiagnosed and of unrecognised depression among the residents of Gerontology Centre in Sarajevo.Methods: This is a cross-sectional, descriptive, and analytical study undertaken throughout May and June 2011 on the sample of 150 residents of “The Gerontology Centre“ in Sarajevo that were above 65 years of age. The following instruments were used for the research: the Geriatric Depression Scale (GDS), modified questionnaire consisting of two parts (general data and data related to health state), and the medical records of the residents. For statistic analysis of data was used the SPSS program for Windows.Results: According to GDS, prevalence of depression was 65.3%, out of which mild depression occurred in 46.7% cases and severe depression in 18.7%. The prevalence of verified (diagnosed) depression was 11.3per cents.Conclusions: According to the GD scale, unrecognised depressions seem to be almost six times more frequent (65.3:11%) than is the case with depressions diagnosed in medical records of the protégées of theGerontology Centre in Sarajevo. Timely recognition of depression and its treating in institutions for protection of health of persons in third age of life can substantially improve the quality of life of these patients.

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Prevalence of idiopathic normal pressure hydrocephalus: A prospective, population-based study

PLoS ONE ◽

10.1371/journal.pone.0217705 ◽

2019 ◽

Vol 14 (5) ◽

pp. e0217705 ◽

Cited By ~ 15

Author(s):

Johanna Andersson ◽

Michelle Rosell ◽

Karin Kockum ◽

Otto Lilja-Lund ◽

Lars Söderström ◽

...

Keyword(s):

Normal Pressure Hydrocephalus ◽

Normal Pressure ◽

Population Based ◽

Idiopathic Normal Pressure Hydrocephalus ◽

Population Based Study

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Predicting Successful Aging in a Population-Based Sample of Georgia Centenarians

Current Gerontology and Geriatrics Research ◽

10.1155/2010/989315 ◽

2010 ◽

Vol 2010 ◽

pp. 1-9 ◽

Cited By ~ 29

Author(s):

Jonathan Arnold ◽

Jianliang Dai ◽

Lusine Nahapetyan ◽

Ankit Arte ◽

Mary Ann Johnson ◽

...

Keyword(s):

Cardiovascular Disease ◽

At Risk ◽

Chronic Diseases ◽

Successful Aging ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Population Based ◽

Control Group ◽

Geriatric Depression ◽

Prevalence Of Depression

Used a population-based sample (Georgia Centenarian Study, GCS), to determine proportions of centenarians reaching 100 years as (1) survivors (43%) of chronic diseases first experienced between 0–80 years of age, (2) delayers (36%) with chronic diseases first experienced between 80–98 years of age, or (3) escapers (17%) with chronic diseases only at 98 years of age or older. Diseases fall into two morbidity profiles of 11 chronic diseases; one including cardiovascular disease, cancer, anemia, and osteoporosis, and another including dementia. Centenarians at risk for cancer in their lifetime tended to be escapers (73%), while those at risk for cardiovascular disease tended to be survivors (24%), delayers (39%), or escapers (32%). Approximately half (43%) of the centenarians did not experience dementia. Psychiatric disorders were positively associated with dementia, but prevalence of depression, anxiety, and psychoses did not differ significantly between centenarians and an octogenarian control group. However, centenarians were higher on the Geriatric Depression Scale (GDS) than octogenarians. Consistent with our model of developmental adaptation in aging, distal life events contribute to predicting survivorship outcome in which health status as survivor, delayer, or escaper appears as adaptation variables late in life.

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Screening for depressive symptoms in older adults in the Family Health Strategy, Porto Alegre, Brazil

Revista de Saúde Pública ◽

10.1590/s0034-8910.2014048004660 ◽

2014 ◽

Vol 48 (3) ◽

pp. 368-377 ◽

Cited By ~ 14

Author(s):

Eduardo Lopes Nogueira ◽

Leonardo Librelotto Rubin ◽

Sara de Souza Giacobbo ◽

Irenio Gomes ◽

Alfredo Cataldo Neto

Keyword(s):

Older Adults ◽

Community Health ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Family Health ◽

Severe Depression ◽

Female Gender ◽

Geriatric Depression ◽

Self Rated Health ◽

Prevalence Of Depression

OBJECTIVE To analyze the prevalence of depression in older adults and associated factors. METHODS Cross-sectional study using a stratified random sample of 621 individuals aged ≥ 60 from 27 family health teams in Porto Alegre, RS, Southern Brazil, between 2010 and 2012. Community health agents measured depression using the 15-item Geriatric Depression Scale. Scores of ≥ 6 were considered as depression and between 11 and 15 as severe depression. Poisson regression was used to search for independent associations of sociodemographic and self-perceived health with both depression and its severity. RESULTS The prevalence of depression was 30.6% and was significantly higher in women (35.9% women versus 20.9% men, p < 0.001). The variables independently associated with depression were: female gender (PR = 1.4, 95%CI 1.1;1.8); low education, especially illiteracy (PR = 1.8, 95%CI 1.2;2 6); regular self-rated health (OR = 2.2, 95%CI 1.6;3.0); and poor/very poor self-rated health (PR = 4.0, 95%CI 2.9;5.5). Except for education, the strength of association of these factors increases significantly in severe depression. CONCLUSIONS A high prevalence of depression was observed in the evaluations conducted by community health agents, professionals who are not highly specialized. The findings identified using the 15-item Geriatric Depression Scale in this way are similar to those in the literature, with depression more associated with low education, female gender and worse self-rated health. From a primary health care strategic point of view, the findings become still more relevant, indicating that community health agents could play an important role in identifying depression in older adults.

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Prevalence of depression among elderly population in rural South India

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20202502 ◽

2020 ◽

Vol 7 (6) ◽

pp. 2377

Author(s):

Vivin Vincent ◽

Jeevithan Shanmugam ◽

Shanmugapriya Duraisamy ◽

Padmavathy Loganathan ◽

Vijay Ganeshkumar ◽

...

Keyword(s):

Rural Areas ◽

South India ◽

Tertiary Care ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Severe Depression ◽

The Elderly ◽

Care Hospital ◽

Cross Sectional ◽

Prevalence Of Depression

Background: Depression among elderly is the commonest psychiatric disorder however it is commonly misdiagnosed and under treated. Most of the time it is considered as part of aging process rather than a treatable condition. Diagnosing depression in the elderly is often difficult as a result of presence of cognitive impairment as well as reluctance and denial by the elderly and their family members. Objective of the study was to estimate the prevalence of depression among elderly rural population in South India. Methods: A community based cross sectional study was conducted over a period of 2 months among 575 elderly people aged 60 years and above in the rural field practice area of a tertiary care hospital in south India using a pre validated Geriatric Depression Scale. Data entered and analysed using MS Excel.Results: 77.56% of the study participants were found to be depressed. Among them 74.66% were mild depressive and 25.34% had severe depression. Depression was common in elderly males as compared to females. The prevalence of depression was higher in those who live single and those living with their children without their spouse and those with co morbidities.Conclusions: Prevalence of depression among elderly is high in rural areas. It also increases as the age increases. Early identification and timely intervention would promote healthy old age.

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Waiting time for surgery influences the outcome in idiopathic normal pressure hydrocephalus — a population-based study

Acta Neurochirurgica ◽

10.1007/s00701-021-05085-7 ◽

2021 ◽

Author(s):

Christine Chidiac ◽

N. Sundström ◽

M. Tullberg ◽

L. Arvidsson ◽

M. Olivecrona

Keyword(s):

Clinical Outcome ◽

Waiting Time ◽

Normal Pressure Hydrocephalus ◽

Normal Pressure ◽

Population Based ◽

Idiopathic Normal Pressure Hydrocephalus ◽

Shunt Surgery ◽

Timed Up And Go ◽

Population Based Study ◽

Quality Registry

Abstract Introduction Idiopathic normal pressure hydrocephalus (iNPH) is a disease that comes with a great impact on the patient’s life. The only treatment for iNPH, which is a progressive disease, is shunt surgery. It is previously indicated that early intervention might be of importance for the outcome. Aim To investigate if a longer waiting time for surgery, negatively influences the clinical outcome. Methods Eligible for this study were all iNPH patients (n = 3007) registered in the Swedish Hydrocephalus Quality Registry (SHQR) during 1st of January 2004–12th of June 2019. Waiting time, defined as time between the decision to accept a patient for surgery and shunt surgery, was divided into the intervals ≤ 3, 3.1–5.9 and ≥ 6 months. Clinical outcome was assessed 3 and 12 months after surgery using the modified iNPH scale, the Timed Up and Go (TUG) test and the mini mental state examination (MMSE). Results Three months after surgery, 57% of the patients with ≤ 3 months waiting time showed an improvement in modified iNPH scale (≥ 5 points) whereas 52% and 46% of patients with 3.1–5.9 and ≥ 6 months waiting time respectively improved (p = 0.0115). At 12 months of follow-up, the corresponding numbers were 61%, 52% and 51% respectively (p = 0.0536). Conclusions This population-based study showed that in patients with iNPH, shunt surgery should be performed within 3 months of decision to surgery, to attain the best outcome.

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