Morphogenesis of the amphibian limb blastema: The relationship between pattern and form

Development ◽  
1984 ◽  
Vol 79 (1) ◽  
pp. 165-181
Author(s):  
Nigel Holder ◽  
Susan Reynolds

A relationship between pattern formation and field shape is established following the formation of rounded blastemas on lower arm limb stumps after treatment with vitamin A. Pattern formation is not affected by alteration in blastemal shape caused by removal of the dermis from the thigh region of the leg. We conclude, therefore, that blastemal shape does not play a causal role in establishing limb pattern. Data relating the number of cells present between the cardinal axial poles of blastemas and the size of blastemas is discussed in terms of short arc intercalation and short range cell—cell interactions during pattern regulation.

1956 ◽  
Vol 15 (2) ◽  
pp. 400-406
Author(s):  
I. R. Sibbald ◽  
J. P. Bowland ◽  
R. T. Berg

1998 ◽  
Vol 76 (9) ◽  
pp. 1795-1796 ◽  
Author(s):  
Steven R Scadding ◽  
Andrew Burns

The purpose of this investigation was to determine whether there were any asymmetries in the vascularization of the limb-regeneration blastema in the axolotl, Ambystoma mexicanum, that might be related to pattern formation, and to determine if retinoic acid could modify the vascular patterns of the blastema. We used acrylic casts of the vascular system of the limbs to assess the pattern of vascularization. We observed a very regular symmetrical arrangement of capillaries in the limb-regeneration blastema that did not appear to be modified by doses of retinoic acid sufficient to modify the limb pattern.


1970 ◽  
Vol 7 (3) ◽  
pp. 695-709
Author(s):  
C. H. O'NEILL ◽  
E. A. C. FOLLETT

The relationship between culture density and the number of microvilli on the cell surface has been studied using BHK21 cells in established monolayer culture. The number of microvilli can be estimated quantitatively by a scanning electron-microscope technique. It can be increased by applying specific antiserum, but whether antibody is applied or not a significant number of cells regularly bear microvilli. This number is characteristic of the culture density. In sparse cultures above a certain minimum density it is relatively high, and in confluent cultures it is much reduced. These results indicate that microvilli may be inhibited by cell contact.


1998 ◽  
Vol 19 (1) ◽  
pp. 34-41 ◽  
Author(s):  
Anita V. Shankar ◽  
Joel Gittelsohn ◽  
Elizabeth K. Pradhan ◽  
Chandra Dhungel ◽  
Keith P. West

This case–control study compares the home garden and animal husbandry practices of households with and without xerophthalmic children in south-central Nepal, focusing on the relationship between these practices and household intake of vitamin A–rich foods. Eighty-one households with a child between the ages of one and six years diagnosed with xerophthalmia (cases) and 81 households with an age-matched, non-xerophthalmic child (controls) were studied. There was little difference between case and control households in the size of their gardens. However, case households were significantly less likely to plant carotenoid-rich vegetables from October to March than were control households (odds ratio, 0.39; 95% confidence interval, 0.16 to 0.96). The mean consumption of non-carotenoid-rich vegetables, but not of carotenoid-rich vegetables, increased linearly with garden size. Case households were significantly more likely than control households to rent domesticated animals from others (χ2 = 5.91; p < .05). Control households were more likely than case households to own chickens and pigeons (χ2 = 6.6–9.2; p < .05). During specific seasons, household meat consumption was significantly lower in case households, regardless of access to animals. Case households appeared to have significantly lower intakes of key vitamin A–rich foods, particularly green leaves and meat, regardless of their socio-economic level (as determined by ownership of material goods), access to animals, or availability of home gardens.


Author(s):  
Hiroyuki Ide ◽  
Yasushi Ohkubo ◽  
Sumihare Noji ◽  
Shigehiko Taniguchi

2021 ◽  
Vol 10 (1) ◽  
pp. 72
Author(s):  
Melvanda Gisela Putri ◽  
Roedi Irawan ◽  
Indri Safitri Mukono

ABSTRAKLatar Belakang: Stunting merupakan suatu istilah yang menggambarkan kondisi pertumbuhan tinggi badan kurang berdasarkan umur disesuaikan dengan Z-Score (<-2SD). Stunting pada balita dapat diakibatkan oleh kurangnya asupan zat gizi yang diperlukan bagi pertumbuhan anak. Penelitian dilakukan untuk mengetahui hubungan suplementasi vitamin A, pemberian imunisasi dan riwayat penyakit infeksi yakni diare dan ISPA terhadap kejadian stunting.Tujuan: Mengetahui hubungan suplementasi vitamin A, pemberian imunisasi, dan penyakit infeksi terhadap stunting pada anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya.Metode: Penelitian ini merupakan penelitian analitik observasional dengan metode cross sectional. Besar sampel adalah 107 anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya. terdiri dari 25 anak kelompok stunting dan 82 anak kelompok non- stunting. Cara pengambilan data melalui data sekunder posyandu dan wawancara langsung orang tua anak dengan pengisian kuisioner. Data dianalisis menggunakan uji Chi-Square, Fisher Exact, dan Mann Whitney.Hasil: Penelitian ini menunjukkan hasil terdapat hubungan suplementasi vitamin A dengan stunting (p=0,000), tidak ada hubungan antara pemberian imunisasi terhadap stunting (p=0,332). Dalam riwayat penyakit infeksi, frekuensi diare dan ISPA ditemukan tidak ada hubungan dengan  stunting (p=0,053 dan p=0,082), begitu pula pada lama diare dan lama ISPA tidak berhubungan dengan stunting (p= 0,614 dan p=0,918).Kesimpulan: Suplementasi vitamin A berhubungan signifikan dengan stunting yang diamati pada anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya. Kata kunci: kejadian stunting, vitamin A, imunisasi, penyakit infeksi, anak usia 24-59 bulanABSTRACTBackground: Stunting is a term that describes condition of lower height-for-age Z-Score (<-2SD). Stunting among children can be caused by a lack of nutrients needed for children's growth. This study was conducted to determine the relationship between vitamin A supplementation, immunization and a history of infectious diseases, namely diarrhea and ARI to the incidence of stunting.Objectives: To determine the relationship between vitamin A supplementation, immunization, and history of infectious disease with the incidence of stunting in children aged 24-59 months at Puskesmas Mulyorejo, Surabaya.Methods: This study was an observational analytic study with cross sectional method. The sample size was 107 children aged 24-59 months at Puskesmas Mulyorejo, Surabaya. This study consisted of 25 children in the stunting group and 82 children in the non-stunting group. The method of data collection was through secondary data from posyandu and direct interviews with parents by filling out questionnaires. Data were analyzed using the chi-square test, fisher exact, and Mann Whitney.Results: The results of this study indicated that there was a relationship between vitamin A supplementation and with stunting (p = 0.000). There was no relationship between immunization and stunting (p = 0.332). In the history of infectious diseases, the frequency of diarrhea and ARI was found to have no relationship with stunting (p = 0.053 and p = 0.082), as well as the duration of diarrhea and duration of ARI there was no association with the stunting (p = 0.614 and p = 0.918).Conclusion: Vitamin A supplementation has significant relationship with stunting in children aged 24-59 months at Puskesmas Mulyorejo, Surabaya.


2018 ◽  
Author(s):  
Wasim A Iqbal ◽  
Gavin B Stewart ◽  
Ines Mendes ◽  
Kieran Finney ◽  
Anthony Oxley ◽  
...  

The proposed protocol is for a systematic review and meta-analysis on the relationship between vitamin A and body mass. The primary objective is to explore the mechanisms between vitamin A and adiposity such as inflammation, dietary intake and body fat. The secondary objective is to look at the extent to which vitamin A is stored in different adipose tissue depots. The protocol outlines the motive and scope for the review, and methodology including the risk of bias, statistical analysis, screening and study criteria.


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