scholarly journals Prevalence of and Risk Factors for Abdominal Bleeding in Patients with External Duodenal Fistula

2018 ◽  
Vol 24 ◽  
pp. 9317-9323
Author(s):  
Zheng Yao ◽  
Zheng Ge ◽  
Xin Xu ◽  
Peilong Pu ◽  
Xuequn Ren ◽  
...  
Keyword(s):  
Risk Factors ◽  
Duodenal Fistula ◽  
Abdominal Bleeding

scholarly journals Uretero-duodenal fistula: Risk factors and management

2022 ◽  
Vol 41 ◽  
pp. 101969
Author(s):  
Joshua Makary ◽  
Peter Galloway ◽  
Pascal Mancuso
Keyword(s):  
Risk Factors ◽  
Duodenal Fistula

scholarly journals Risk Factors and Outcome for Massive Intra-Abdominal Bleeding Among Patients With Infected Necrotizing Pancreatitis

Medicine ◽  
2015 ◽  
Vol 94 (28) ◽  
pp. e1172 ◽  
Author(s):  
Xiao Shen ◽  
Jing Sun ◽  
Jingzhu Zhang ◽  
Lu Ke ◽  
Zhihui Tong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Necrotizing Pancreatitis ◽  
Abdominal Bleeding

scholarly journals ANALYSIS OF EARLY RELAPAROTOMY IN OBSTETRIC & GYNAECOLOGICAL SURGERIES

2016 ◽  
Vol 21 (4) ◽  
pp. 247
Author(s):  
Shumaila Zia ◽  
Muhammad Rafique ◽  
Muhammad Atif Qureshi ◽  
Baha Ahmad
Keyword(s):  
Risk Factors ◽  
Placenta Previa ◽  
Tertiary Care ◽  
Fresh Frozen Plasma ◽  
Maternal Deaths ◽  
Packed Red Blood Cells ◽  
Abdominal Bleeding ◽  
Primary Surgery ◽  
Fresh Frozen ◽  
Early Relaparotomy

AbstractObjectives:Evaluation of risk factors, frequency, causes and measures took to save patients life in relaparotomies.Methods:This retrospective, descriptive study was conducted from January 2012 December 2014 in a tertiary care hospital.Results:This study includes 38 cases, 29 (76.3%) obstetrical and nine (23.7%) gynaecological Relaparotomy incidence was 0.43%. It was 0.55% for obstetrical and 0.24% for gynaecological indications. The leading causes were suspected intra-abdominal bleeding in 24 (63.2%), uncontrolled postpartum haemorrhage (PPH) in nine (23.7%) and suspected abdominal caesarean sections (CS) 28/29(96.5%). Of 28 previous CS cases, multiple CS were in13 (46.4%), placenta previa in five (17.85%) and antepartum hemorrhage in four (14.28%) cases. Majority (92.1%) of patients underwent relaparotomy within 24 hours after primary surgery. Patients received (mean SD) 7.2 5.4 packed red blood cells, 4.3 5.5 fresh frozen plasma and 1.2 2.3 platelets units. Third operation was needed in seven (18.4%) cases. Twelve (31.6%) women develo-ped complications. There were three (7.9%) maternal deaths following relaparotomy.Conclusion:Intra-abdominal bleeding is main cause for reoperation and multiple CS is major risk factor. Recognition of risk factors, careful primary operation, involvement of seniors in complicated surgeries and early intervention can prevent majority of the relaparotomies.Key words:Relaparotomy, reoperation, complicated caesarean section, maternal mortality, obstetrics and gynaecology, intra-peritoneal haemorrhage.

Risk Factors for Reoperation Following Radical Gastrectomy in Gastric Cancer Patients

2021 ◽  
pp. 000313482110508
Author(s):  
Dong-Hwan Kim ◽  
Ji-Ho Park ◽  
Tae Han Kim ◽  
Eun-Jung Jung ◽  
Chi-Young Jeong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Small Bowel ◽  
Small Bowel Obstruction ◽  
Bowel Obstruction ◽  
Radical Gastrectomy ◽  
Factors Associated ◽  
Abdominal Bleeding ◽  
Independent Risk Factors ◽  
Gastric Cancer Patients

Background Reoperation due to elective surgery complications is very mentally, physically, and economically detrimental to patients. This study investigated the potential risk factors associated with early reoperation after radical gastrectomy in gastric cancer patients and included an in-depth analysis of these risk factors. Methods This retrospective study reviewed 1568 patients with gastric cancer. Grade 3 or greater complications were defined as severe. Any factors related to reoperation after radical gastrectomy were analyzed in patients with severe local complications. Results Among 1537 patients undergoing radical gastrectomy, 115 (7.5%) patients had severe postoperative complications, 98 (6.38%) of whom experienced severe local complications. The most common local complication was anastomotic leakage (31, 2.02%), followed by intra-abdominal abscess (30, 1.95%), pancreatic leakage (22, 1.43%), duodenal stump leakage (18, 1.17%), intra-abdominal bleeding (12, .78%), intraluminal bleeding (8, .52%), small bowel obstruction (5, .32%), and chyle leakage (3, .19%). Of these patients, 26 (1.69%) underwent reoperation, and 6 (.39%) died. In the univariate analysis of clinical factors related to reoperation, intra-abdominal bleeding and small bowel obstruction were risk factors for reoperation, and intra-abdominal bleeding (odds ratio [OR] = 9.57, confidence interval [CI] = 2.65-40.20, P < .001) and small bowel obstruction (OR = 19.14, CI = 2.60-390.13, P = .011) were independent risk factors associated with reoperation in the multivariate analysis. Conclusion Intra-abdominal bleeding and small bowel obstruction are independent risk factors for reoperation following radical gastrectomy. Patients with postoperative intra-abdominal bleeding and small bowel obstruction need to be warned about reoperation.

Elevated level of circulatory sTLT1 induces inflammation through SYK/MEK/ERK signalling in coronary artery disease

2019 ◽  
Vol 133 (22) ◽  
pp. 2283-2299
Author(s):  
Apabrita Ayan Das ◽  
Devasmita Chakravarty ◽  
Debmalya Bhunia ◽  
Surajit Ghosh ◽  
Prakash C. Mandal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Chronic Inflammation ◽  
Ex Vivo ◽  
Human Subjects ◽  
Critical Role ◽  
Atherosclerotic Cardiovascular Disease ◽  
Tnf Α ◽  
Artery Disease

Abstract The role of inflammation in all phases of atherosclerotic process is well established and soluble TREM-like transcript 1 (sTLT1) is reported to be associated with chronic inflammation. Yet, no information is available about the involvement of sTLT1 in atherosclerotic cardiovascular disease. Present study was undertaken to determine the pathophysiological significance of sTLT1 in atherosclerosis by employing an observational study on human subjects (n=117) followed by experiments in human macrophages and atherosclerotic apolipoprotein E (apoE)−/− mice. Plasma level of sTLT1 was found to be significantly (P<0.05) higher in clinical (2342 ± 184 pg/ml) and subclinical cases (1773 ± 118 pg/ml) than healthy controls (461 ± 57 pg/ml). Moreover, statistical analyses further indicated that sTLT1 was not only associated with common risk factors for Coronary Artery Disease (CAD) in both clinical and subclinical groups but also strongly correlated with disease severity. Ex vivo studies on macrophages showed that sTLT1 interacts with Fcɣ receptor I (FcɣRI) to activate spleen tyrosine kinase (SYK)-mediated downstream MAP kinase signalling cascade to activate nuclear factor-κ B (NF-kB). Activation of NF-kB induces secretion of tumour necrosis factor-α (TNF-α) from macrophage cells that plays pivotal role in governing the persistence of chronic inflammation. Atherosclerotic apoE−/− mice also showed high levels of sTLT1 and TNF-α in nearly occluded aortic stage indicating the contribution of sTLT1 in inflammation. Our results clearly demonstrate that sTLT1 is clinically related to the risk factors of CAD. We also showed that binding of sTLT1 with macrophage membrane receptor, FcɣR1 initiates inflammatory signals in macrophages suggesting its critical role in thrombus development and atherosclerosis.

The Preschool Stuttering Screen for Health Care Professionals

2011 ◽  
Vol 21 (2) ◽  
pp. 59-62
Author(s):  
Joseph Donaher ◽  
Christina Deery ◽  
Sarah Vogel
Keyword(s):  
Risk Factors ◽  
Health Care ◽  
Differential Diagnosis ◽  
Preschool Children ◽  
Health Care Professionals ◽  
Healthcare Professionals ◽  
Evidence Based ◽  
Developmental Profile

Healthcare professionals require a thorough understanding of stuttering since they frequently play an important role in the identification and differential diagnosis of stuttering for preschool children. This paper introduces The Preschool Stuttering Screen for Healthcare Professionals (PSSHP) which highlights risk factors identified in the literature as being associated with persistent stuttering. By integrating the results of the checklist with a child’s developmental profile, healthcare professionals can make better-informed, evidence-based decisions for their patients.

Clinical Response to Questions Regarding Outcomes and Therapy Efficacy

2010 ◽  
Vol 20 (3) ◽  
pp. 76-83 ◽  
Author(s):  
Joseph Donaher ◽  
Tom Gurrister ◽  
Irving Wollman ◽  
Tim Mackesey ◽  
Michelle L. Burnett
Keyword(s):  
Risk Factors ◽  
Clinical Response ◽  
Speech Language Pathologists ◽  
Specific Therapy ◽  
Therapy Efficacy ◽  
Therapy Program ◽  
Adults Who Stutter ◽  
Cure Rates

Parents of children who stutter and adults who stutter frequently ask speech-language pathologists to predict whether or not therapy will work. Even though research has explored risk-factors related to persistent stuttering, there remains no way to determine how an individual will react to a specific therapy program. This paper presents various clinicians’answers to the question, “What do you tell parents or adults who stutter when they ask about cure rates, outcomes, and therapy efficacy?”

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