scholarly journals Prevalence of Fibromyalgia in chronic kidney disease pre-dialysis patients: Experience from a Tertiary Care Renal unit in Pakistan

2021 ◽  
Vol 37 (7) ◽  
Author(s):  
Zara Khan ◽  
Rubina Naqvi
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Tertiary Care ◽  
Stage Iii ◽  
Renal Unit ◽  
Dialysis Patients ◽  
Ckd Stage ◽  
Patients Experience

Background and Objective: Fibromyalgia syndrome (FMS) is a well-established medical problem which gives rise pain at various sites, fatigue, sleep disturbances, poor memory and definitely affects quality of life. Its prevalence in chronic kidney disease (CKD) is scarcely reported, thus we aimed to assess this condition and report its prevalence in our population. Methods: The current study was carried out in all adult CKD stage III and IV patients registered from January 2020 to July 2020 at outpatient department of a tertiary care renal institution in Karachi, Pakistan. This is a cross sectional study where prevalence of FMS was assessed by interviewing and examining patients according to established criteria for FMS. All data and laboratory parameters were recorded on a proforma and statistical analysis was done on SPSS version22.0. Results: During the study period of six months, 161 patients with CKD stage III and IV were registered. Among these 81 male and 80 were females. Mean age was 47.12±9.27 (range 21-60) years. There were 22 (13.66%) patients found to have FMS. Mean Widespread Pain Index (WPI) score was 5.68±4.36 (range 1-16), while severity scale (SS) 2a was 3.17±1.78 (range 1-9) and SS2b 2.04±0.96 (range 1-5) was recorded. Conclusion: From Pakistan prevalence of FMS has never been published. As this syndrome affects quality of life of patients, its recognition and proper management is immensely required. doi: https://doi.org/10.12669/pjms.37.7.4474 How to cite this:Khan Z, Naqvi R. Prevalence of Fibromyalgia in chronic kidney disease pre-dialysis patients: Experience from a Tertiary Care Renal unit in Pakistan. Pak J Med Sci. 2021;37(7):---------. doi: https://doi.org/10.12669/pjms.37.7.4474 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals HUBUNGAN KOMPLIKASI INTRA HEMODIALISIS DENGAN KUALITAS HIDUP PADA PASIEN CHRONIC KIDNEY DISEASE (CKD) STAGE V YANG MENJALANI HEMODIALISIS DI RUANG HEMODIALISA BRSU TABANAN TAHUN 2017

2018 ◽  
Vol 2 (1) ◽  
pp. 9
Author(s):  
Kadek G Pebriantari ◽  
IGA Puja Astuti Dewi
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Significant Relationship ◽  
Chi Square ◽  
Cross Sectional ◽  
Probability Sampling ◽  
Ckd Stage ◽  
Non Parametric

ABSTRAKLatar Belakang. Hemodialisis aman dan bermanfaat untuk pasien, namun bukan berarti tanpa efek samping. Berbagai komplikasi dapat terjadi pada saat pasien menjalani hemodialisis. Komplikasi ini dapat mengakibatkan timbulnya masalah baru yang lebih kompleks, yaitu dapat mempengaruhi kualitas hidup bahkan menimbulkan kematianTujuan. Untuk mengetahui hubungan komplikasi intra hemodialisis dengan kualitas hidup  pada pasien Chronic Kidney Disease (CKD) Stage V yang menjalani hemodialisis.Metode. Jenis penelitian adalah analitik korelasional dengan pendekatan cross-sectional. Sampel pada penelitian ini berjumlah 166 responden diambil dengan teknik non probability sampling yaitu total sampling. Pengumpulan data menggunakan kuesioner dan lembar observasi,dianalisa dengan uji non parametric (Chi Square).Hasil. Rata – rata jumlah komplikasi intra hemodialisis adalah kurang dari dua komplikasi (sedikit komplikasi). Hipertensi intra hemodialisis adalah komplikasi terbanyak yang ditemukan (52,3%). Kejang dan penurunan kesadaran merupakan komplikasi yang tidak pernah dialami oleh responden selama penelitian (0%).Kualitas hidup pasien CKD stage V yang menjalani HD di BRSU Tabanan masuk dalam kategori kualitas baik. Hasil uji statistik diperoleh nilai p < 0.001 bahwa ada hubungan yang signifikan antara komplikasi intra hemodialisis dengan  kualitas hidup pada pasien yang menjalani HD. Dari hasil analisis diperoleh pula nilai OR = 0,005, artinya responden yang memiliki banyak komplikasi mempunyai peluang 0,005 kali memiliki kualitas hidup buruk dibanding responden yang memiliki sedikit komplikasi.Kesimpulan. Ada hubungan yang signifikan antara komplikasi intra hemodialisis dengan  kualitas hidup pada pasien yang menjalani hemodialisis.KataKunci: Komplikasi Intra Hemodialisis, Kualitas Hidup, Hemodialisis ABSTRACTBackground: Hemodialysis is safe and beneficial to the patient. However, there are various complications may occur when the patients undergo hemodialysis. These complications can lead to the emergence of new problems which are more complex and affect to the quality of life and even cause death.Aim: To determine the relationship of intra hemodialysis complications with quality of life in patients with Chronic Stage Kidney Disease (CKD) Stage V who undergo hemodialysis.Method:This study employed correlational analytic design with cross-sectional approach. To conduct this study, there were 166 respondents recruited as the sample by using probability sampling with total sampling technique. The data were collected by using questionnaire and observation sheet. Further, the data were analyzed by non-parametric test (Chi Square).Finding: The findings indicated that the average number of intra hemodialysis complications is less than two complications (few complications). There were found that 52.3% patients who had complication of hypertension intra hemodialysis. On the other hand, there was 0%of the respondents experienced seizures and decreased awareness complications during the study. The quality of life of CKD stage V patients underwenthemodialysis at BRSU Tabanan is categorized as good quality. The statistical test obtained p <0.001, it meant that there was a significant relationship between intra hemodialysis complications with quality of life in patients underwenthemodialysis. It also found that the analysis results of OR = 0.005, it meant that respondents who had many complications have a chance of 0.005 times experienced poor quality of life rather than the patients who had few complications.Conclusion: There is a significant relationship between intra hemodialysis complications and quality of life in patients undergo hemodialysis. Keywords: Complications of Intra Hemodialysis, Quality of Life, Hemodialysis

scholarly journals A Study on Medication Adherence and Quality of Life in Patients with Chronic Kidney Disease

2020 ◽  
Vol 10 (3-s) ◽  
pp. 52-60
Author(s):  
Christeena S Varghese ◽  
Harshita Krishna Naik ◽  
R Sangeetha ◽  
R Srinivasan
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Medication Adherence ◽  
Kidney Disease ◽  
Average Score ◽  
Patient Counselling ◽  
Clinical Issue ◽  
Ckd Stage ◽  
Health Related

Back ground: Chronic Kidney Disease (CKD) is the most common health related problem. Poor long term adherence is the major clinical issue in the management of CKD. Therefore good medication adherence is important to obtain desired therapeutic outcome which in turn improves the quality of life of the patient. The aim of the study is to carry out a study on medication adherence and to improve health related quality of life in patients with CKD. Objectives: To evaluate medication adherence and to assess the factors associated with non adherence and to provide patient counselling to improve medication adherence and to improve their quality of life. Methods: A prospective study conducted for a period of six months in NU Hospitals Bengaluru. A total of 140 patients (62 were undergoing hemodialysis, 66 were CKD stage 3-5 and 12 were post-transplant patients) were enrolled for the study. Patient’s adherence to medication was assessed with the help of Modified Morisky, Green, Levine Medication Adherence Scale and Quality of life was assessed with the help of Kidney Disease Quality of Life-Short Form 36 questionnaire. One to one follow up was done after 3 months of initial data collection. Results: During the study 140 patients were enrolled for the study with 103 males and 37 females. Patient with low and medium adherence during the first visit were 7 (5%) and 21 (45%) respectively and patients with high adherence during baseline visit were 80%, which later improved to 85.7% in the final review after patient counselling. Quality of life is decreased in patients with CKD. The domain with highest average score was emotional well being (8.4) and lowest average score was role limitation due to physical health (4.12). There was a slight improvement in Quality of Life of the patients after patient counselling. Conclusion: Study suggests that patient counselling by clinical pharmacists can improve the medication adherence by improving awareness about medication which in turn helps them to achieve a better quality of life.

scholarly journals INDICATORS OF QUALITY OF LIFE OF PATIENTS WITH CHRONIC KIDNEY DISEASE STAGE II-IV

2020 ◽  
Vol 16 (3) ◽  
pp. 39-43
Author(s):  
I.O. Dudar ◽  
O.M. Loboda ◽  
І.V. Krasyuk ◽  
V.V. Alekseeva
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Diseases ◽  
Stage Ii ◽  
Disease Stage ◽  
Ckd Stage ◽  
The Impact

Relevance. Chronic diseases have a long duration and a rather slow progression, and people who have such diseases want not only to live longer but also to live better. Therefore, quality of life (QOL) is one of the most important health issues for the treatment of chronic diseases. Objective: to determine the features of QOL in patients with chronic kidney disease (CKD) stage II-IV. Materials and methods. In 171 patients with CKD of II-IV centuries, in addition to general clinical and laboratory studies, QOL was studied using a questionnaire to assess the quality of life of SF-36. The questionnaire contains 36 questions of the main module, supplemented by multi-point scales aimed specifically at patients with CKD. The answers were evaluated in points - from 0 to 100. The higher the score, the better the patient's QOL. The total components were also calculated: physical total component, mental total component, total points. The obtained research data were subjected to statistical processing, which included parametric (t-test for samples with unrelated variants) and non-parametric (Mann-Whitney method) methods, correlation analysis was used. Results. Most QOL indicators worsen significantly with the progression of CKD. The indicators of total QOL, as well as the indicator "the impact of the disease on everyday life" are most significantly reduced. Age correlates as much as possible with most indicators of QOL in patients with CKD. With age, the QOL of patients decreases, but the manifestations of the disease increase and the mental and physical condition of patients deteriorate. QOL parameters are probably directly and moderately correlated with hemoglobin levels. Most QOL parameters are significantly moderately correlated with systolic blood pressure and diastolic blood pressure. It is assumed that the correction of anemia and blood pressure control, in addition to a positive effect on disease progression and the occurrence and development of complications, will also improve QOL. There were no significant differences in the assessment of QOL in men and women. Conclusions. QOL indicators decrease with the progression of CKD. Age, hemoglobin level, blood pressure affect QOL.

scholarly journals Evaluation of role of heart rate variability with holter monitoring in chronic kidney disease

2020 ◽  
Vol 8 (6) ◽  
pp. 2188
Author(s):  
Naveen Reddy Avula ◽  
Tusahr Dighe ◽  
Atul Sajgure ◽  
Charan Bale ◽  
Pavan Wakhare
Keyword(s):  
Chronic Kidney Disease ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Kidney Disease ◽  
Kidney Diseases ◽  
Tertiary Care ◽  
Holter Monitoring ◽  
Stage Iii ◽  
Care Hospital ◽  
Ckd Stage

Background: Chronic kidney disease is prevalent disease even in absence of diabetes and hypertension in 12% adults over 65 yrs of age. Autonomic imbalance is not studied in detail which could be a risk factor for chronic kidney disease.Methods: This Study was observational study in a tertiary care Hospital in pune, india and was conducted for a period of 1 year with sample size of 52. All subjects were known cases of chronic kidney disease from stage III to VD. All individuals of age >18yrs and eGFR ≤60ml/min/1.73m2 according to CKD- EPI equation were included in the study and who were not giving consent were excluded. 24 hrs Holter monitoring was done in stages from ckd stages III to V, for ckd stage VD on both Hemodialysis day and Non hemodialysis. Analysis was done using SPSS version 20 (IBM SPSS Statistics Inc., Chicago, Illinois, USA) Windows software program. The paired t test, analysis of variance (ANOVA) and Chi-square test were used. Level of significance was set at p≤0.05.Results: In this study when Heart rate variability (HRV) parameters were compared in different stages of ckd from stage III to VD (on Hemodialysis day) SDNN, SDNN Index were found to be statistically significant and on non Hemodialysis day SDNN Index was found to be statistically significant. In each subgroup of ckd stage V when diabetic subjects were compared with non-diabetic subjects, HRV parameters like ratio of P/S which was found to be low and significant in ckd stage V diabetic subjects.Conclusions: Chronic kidney disease itself can affect the HRV parameters. Causal relationship between HRV and chronic kidney diseases can be vice versa and further needs larger and prospective studies.

The features of comorbid status and its impact on the quality of life of patients with chronic kidney disease on programmed hemodialysis

2021 ◽  
pp. 32-40
Author(s):  
Aksana Mukhamedovna Kardangusheva ◽  
Rustam Khasanovich Keshokov ◽  
Dzhanneta Magometovna Urusbieva ◽  
Albina Anatolievna Pshukova ◽  
Alina Latifovna Betuganova ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Patient Treatment ◽  
Renal Diseases ◽  
Chronic Glomerulonephritis ◽  
Ckd Stage ◽  
Common Causes ◽  
The Individual

The purpose of the research is to study the features of comorbid status in patients with chronic kidney disease (CKD) Stage 5 on programmed hemodialysis (PHD) and its impact on quality of life (QOL). Methodology: we examined 86 patients (60 men and 26 women) with CKD Stage 5 receiving PHD treatment. The average age of the patients was 55.5±13.9 years. The study protocol included an assessment of the QOL level according to the KDQOL-SF™ questionnaire, the comorbidity index according to M.E. Charlson (CCI), clinical and instrumental studies in accordance with clinical guidelines. Results: the most common causes of CKD Stage 5 in the examined patients were chronic glomerulonephritis and diabetes mellitus (26.7% each), tubulointerstitial renal diseases (23.3%) and polycystic kidney disease (13.3%). High and medium levels of CCI were found in 67.4% of the examined patients. Among the comorbidities, cardiovascular diseases rank first (51.2%). QOL of patients with CKD Stage 5 on PHD was characterized by the lowest scores on the scales of physical functioning and the burden of kidney disease. Correlation analysis revealed that comorbidities in patients with CKD Stage 5 who are on PHD negatively affect their QOL. Conclusion: the obtained results can be used in planning and organizing the provision of medical care to patients with CKD. The introduction of the used QOL and CCI assessment methods in the protocol for the management of patients with CKD Stage 5 in dialysis centers will make it possible to monitor the individual QOL indicators of patients, evaluate the effectiveness of patient treatment and correct it in a timely manner.

scholarly journals Serum biomarkers of iron stores are associated with worse physical health-related quality of life (HRQoL) in non-dialysis dependent chronic kidney disease (NDD-CKD) patients with or without anemia

2021 ◽  
Author(s):  
Murilo Guedes ◽  
Daniel Muenz ◽  
Jarcy Zee ◽  
Marcelo Barreto Lopes ◽  
Sandra Waechter ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Saturation Index ◽  
Transferrin Saturation ◽  
Health Related Quality ◽  
Ckd Stage ◽  
Related Quality ◽  
Health Related

ABSTRACT Background Iron deficiency (ID) is a common condition in non-dialysis dependent chronic kidney disease (NDD-CKD) patients that is associated with poorer clinical outcomes. However, the effect of ID on health-related quality of life (HRQoL) in this population is unknown. We analyzed data from a multinational cohort of NDD-CKD stage 3 to 5 patients to test the association between transferrin saturation index (TSAT) and ferritin with HRQoL. Methods Patients from Brazil (N = 205), France (N = 2015), and the US (N = 293) in the CKD Outcomes and Practice Patterns Study (CKDopps, 2013 to 2019) were included. We evaluated the association of TSAT and ferritin (and functional and absolute ID, defined as TSAT ≤ 20% and ferritin &gt;300 or &lt; 50 ng/mL, respectively) on pre-specified HRQoL measures, including KDQOL-36 PCS and MCS as the primary outcomes. Models were adjusted for confounders including hemoglobin (Hgb). Results TSAT ≤15% and both ferritin &lt;50 ng/mL and ≥300 ng/mL were associated with worse PCS scores, but not with MCS. Patients with composite TSAT ≤20% and ferritin &lt;50 or ≥ 300 ng/mL had lower functional status and worse PCS than those with TSAT of 20%-30% and ferritin 50-299 ng/mL. Patients with lower TSAT were less likely to perform intense physical activity. Adjustment for Hgb only slightly attenuated the observed effects. Conclusions Low TSAT levels, as well as both low TSAT with lower ferritin and low TSAT with high ferritin, are associated with worse physical HRQoL in NDD-CKD patients, even after accounting for Hgb level. Interventional studies of iron therapy on HRQoL among NDD-CKD individuals are needed to confirm these findings.

Assessment of health-related quality of life and its determinants in the pre-dialysis patients with chronic kidney disease

2021 ◽  
Author(s):  
Roland Nnaemeka Okoro ◽  
Maxwell Ogochukwu Adibe ◽  
Mathew Jegbefume Okonta ◽  
Ibrahim Ummate ◽  
John David Ohieku ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Health Related Quality ◽  
Dialysis Patients ◽  
Related Quality ◽  
Health Related
Sign in / Sign up

Export Citation Format

Share Document