scholarly journals Making sense of it all: Ethical reflections on the conditions surrounding the first genome-edited babies

2021 ◽  
Vol 5 ◽  
pp. 216
Author(s):  
Qi Chen ◽  
Yonghui Ma ◽  
Markus Labude ◽  
G Owen Schaefer ◽  
Vicki Xafis ◽  
...  

In November 2018 the birth of the first genome-edited human beings was announced by Chinese scientist, He Jiankui. The ensuing ethical controversy, institutional investigations and legal proceedings led to the revision of standards, rules and procedures at many levels. Arguably, however, these developments have not fundamentally changed the conditions or the culture that nourished He Jiankui’s vaulting ambition in the first place and enabled it to find expression. In this paper we explore the clinical, regulatory and societal circumstances of the ‘gene-edited baby’ case, the political, cultural and economic conditions that created a radical and dangerous climate for biotechnology innovation, and the responsibilities of the international research community, many of whose members were apprised of Dr He’s intentions. The aim is not to heap anathemas on the heads of implicated individuals but to draw attention to the need for different communities (researchers, authorities and domestic publics) to play a part actively in the governance of biomedical innovation and for research to be bridled by human values.

2020 ◽  
Vol 5 ◽  
pp. 216
Author(s):  
Qi Chen ◽  
Yonghui Ma ◽  
G Owen Schaefer ◽  
Vicki Xafis ◽  
Markus Labude ◽  
...  

In November 2018 the birth of the first genome-edited human beings was announced. The ensuing ethical controversy, institutional investigations and legal proceedings led to the revision of standards, rules and procedures at many levels. Arguably, however, these developments have not fundamentally changed the conditions or the culture that nourished He Jiankui’s vaulting ambition in the first place and enabled it to find expression. In this paper we explore the clinical, regulatory and societal circumstances of the ‘gene-edited baby’ case, the political, cultural and economic conditions that created a radical and dangerous climate for biotechnology innovation, and the responsibilities of the international research community, many of whose members were apprised of Dr He’s intentions. The aim is not to heap anathemas on the heads of implicated individuals but to draw attention to the need for different communities (researchers, authorities and domestic publics) actively to play a part in the governance of biomedical innovation and for research to be bridled by human values.


2018 ◽  
Vol 3 (2) ◽  

Philosophy is a search for a general understanding of values and reality by chiefly speculative rather than observational means. It signifies a natural and necessary urge in human beings to know themselves and the world in which they live and move and have their being. Hindu philosophy is intensely spiritual and has always emphasized the need for practical realization of Truth. Philosophy is a comprehensive system of ideas about human nature and the nature of the reality we live in. It is a guide for living, because the issues it addresses are basic and pervasive, determining the course we take in life and how we treat other people. Hence we can say that all the aspects of human life are influenced and governed by the philosophical consideration. As a field of study philosophy is one of the oldest disciplines. It is considered as a mother of all the sciences. In fact it is at the root of all knowledge. Education has also drawn its material from different philosophical bases. Education, like philosophy is also closely related to human life. Therefore, being an important life activity education is also greatly influenced by philosophy. Various fields of philosophy like the political philosophy, social philosophy and economic philosophy have great influence on the various aspects of education like educational procedures, processes, policies, planning and its implementation, from both the theoretical and practical aspects. In order to understand the concept of Philosophy of education it is necessary to first understand the meaning of the two terms; Philosophy and Education.


2019 ◽  
Vol 35 (3) ◽  
pp. 327-351
Author(s):  
Omar Velasco Herrera

Durante la primera mitad del siglo xix, las necesidades presupuestales del erario mexicano obligaron al gobierno a recurrir al endeudamiento y al arrendamiento de algunas de las casas de moneda más importantes del país. Este artículo examina las condiciones políticas y económicas que hicieron posible el relevo del capital británico por el estadounidense—en estricto sentido, californiano—como arrendatario de la Casa de Moneda de México en 1857. Asimismo, explora el desarrollo empresarial de Juan Temple para explicar la coyuntura política que hizo posible su llegada, y la de sus descendientes, a la administración de la ceca de la capital mexicana. During the first half of the nineteenth century, the budgetary needs of the Mexican treasury forced the government to resort to borrowing and leasing some of the most important mints in the country. This article examines the political and economic conditions that allowed for the replacement of British capital by United States capital—specifically, Californian—as the lessee of the Mexican National Mint in 1857. It also explores the development of Juan Temple’s entrepreneurship to explain the political circumstances that facilitated his admission, and that of his descendants, into the administration of the National Mint in Mexico City.


Author(s):  
Alan L. Mittleman

This chapter moves into the political and economic aspects of human nature. Given scarcity and interdependence, what sense has Judaism made of the material well-being necessary for human flourishing? What are Jewish attitudes toward prosperity, market relations, labor, and leisure? What has Judaism had to say about the political dimensions of human nature? If all humans are made in the image of God, what does that original equality imply for political order, authority, and justice? In what kinds of systems can human beings best flourish? It argues that Jewish tradition shows that we act in conformity with our nature when we elevate, improve, and sanctify it. As co-creators of the world with God, we are not just the sport of our biochemistry. We are persons who can select and choose among the traits that comprise our very own natures, cultivating some and weeding out others.


Author(s):  
Philip Goff

This is the first of two chapters discussing the most notorious problem facing Russellian monism: the combination problem. This is actually a family of difficulties, each reflecting the challenge of how to make sense of everyday human and animal experience intelligibly arising from more fundamental conscious or protoconscious features of reality. Key challenges facing panpsychist and panpsychist forms of Russellian monism are considered. With respect to panprotopsychism, there is the worry that it collapses into noumenalism: the view that human beings, by their very nature, are unable to understand the concrete, categorical nature of matter. With respect to panpsychism, there is the subject-summing problem: the difficulty making sense of how micro-level conscious subjects combine to produce macro-level conscious subjects. A solution to the subject-summing problem is proposed, and it is ultimately argued that panpsychist forms of the Russellian monism are to be preferred on grounds of simplicity and elegance.


Author(s):  
Liubov Vetoshkina ◽  
Yrjö Engeström ◽  
Annalisa Sannino

By skillfully shaping and producing objects human beings externalize and make real their future-oriented imaginaries and visions. Material objects created by skilled performance make human lifeworlds durable. From the point of view of history making, wooden boat building is a particularly rich domain of skilled performance. This chapter is based on two research sites, one in Finland and the other in Russia. The analysis is divided into four layers or threads of history making, namely personal history, the history of the wooden boat community, the political history of the nations and their relations, and the history of the boats themselves as objects of boat-building activity. The chapter ends by discussing our findings and their implications for the understanding of skilled performance and history making in work activities and organizations.


2019 ◽  
Vol 24 (1) ◽  
pp. 375-392
Author(s):  
Mads Peter Karlsen

AbstractThe first section of this paper argues that we can find in Kierkegaard an idea of equality, epitomized in the notion of “the neighbor” presented in Works of Love, which is highly relevant for, among other things, a critical engagement with today’s “identity politics.” The second section argues that Kierkegaard’s idea of equality is a religious-existential task, but also a task concerning our relationship with other human beings. The third section demonstrates how this idea of equality is evinced in the notion of “the neighbor.” The last section offers some reflections on how we might begin to rethink the political based on this idea of equality.


2013 ◽  
Vol 17 (2) ◽  
pp. 150-160 ◽  
Author(s):  
Caterina Scaramelli

This paper takes water quality as an ethnographic subject. It looks at how water quality monitors in Boston make sense of the quality of water through mundane engagement with three non-human beings who they encounter during their monitoring activities: herring, bacteria and water lily. Each of these organisms suggests a different understanding of water quality for the monitors and poses a dilemma. Water quality monitors who contribute to the production of water quality data come to know water quality as through direct interactions with these beings, mediated by both sensorial experience and laboratory data. These experiences, at the same time, confuse and redraw relationships between science, water flows, non-human vitality, including that of invasive species, and people.


2019 ◽  
Vol 49 (2) ◽  
pp. 193-209 ◽  
Author(s):  
Stefano Ruzza ◽  
Giuseppe Gabusi ◽  
Davide Pellegrino

AbstractStarting from the imperfect nature of Myanmar's democracy, this paper aims to answer two questions. First, can Myanmar's transition be defined as a case of democratization, or is it, rather, a case of authoritarian resilience? To state this differently: is the progress enjoyed by Myanmar's polity the outcome of an ongoing process that is supposed to lead to a fully fledged democracy, or, rather, an attempt to enshrine elements of authoritarian governance under a democratic guise? Second, if the balance leans towards the latter instead of the former, how did authoritarian resilience work in Myanmar? The transition is analysed from a long-term perspective, moving from the 1988 pro-democracy uprising up to the most recent events. Data were collected from available published sources and from three fieldworks conducted by the authors in Myanmar. The paper concludes that Myanmar's transition is better understood as a case of authoritarian resilience than as democratization and highlights three core traits of Myanmar's authoritarian resilience: first, the very top-down nature of the political transformation; second, the incumbents’ ability to set the pace of political reform through the use of repression and political engineering; and third, the divide-and-rule strategy used as a means to keep contestations separated and local.


1973 ◽  
Vol 8 (4) ◽  
pp. 432-454 ◽  
Author(s):  
J. M. Maravall

THIS ARTICLE ATTEMPTS TO DISCUSS A NUMBER OF QUESTIONS RELATED to the development of a working-class movement of dissent under non-democratic conditions. In this discussion particular attention will be given to the consequences of economic development. It is not that economic development will be considered as a cross-culturally invariant factor in the explanation of social and political conflict and dissent, but that given i) a non-democratic political context and ii) social and economic conditions allowing for working-class movements whose open manifestation is hence restricted by the political set of constraints, the effects of economic development upon such contradictory conditions, and the way they influence the pattern of development of the working-class movement will be especially considered.


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