Morbidity of Children's Population of Lermontov City, Located in the Uranium Legacy Area

2021 ◽  
Vol 66 (5) ◽  
pp. 78-84
Author(s):  
A. Lyaginskaya ◽  
N. Shandala ◽  
A. Titov ◽  
E. Metlyaev ◽  
V. Kuptsov ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Skin Diseases ◽  
Subcutaneous Tissue ◽  
Population Estimates ◽  
Malignant Neoplasms ◽  
Biomedical Data ◽  
Radiation Background ◽  
Child Population ◽  
High Incidence ◽  
Chronic Morbidity

Purpose: To carry out assessment the health status of the child population of the Lermontov city. This child population living in the area, of uranium legacy, and they are critical group of the population in terms of sensitivity to adverse environmental factors. Materials and methods: The object of the study was the morbidity of children 0–14 years old (primary, chronic, oncological). The research material was the data of reporting forms of medical statistics, presented in the following forms: 7 – information on malignant neoplasms and 12 - information on the number of diseases in children. The development included data from Clinical hospital # 101 of the FMBA of Russia for 2014–2018. Statistical data processing was carried out using standard methods used for the analysis of biomedical data. Results: The morbidity of children 0–14 years old in Lermontov in 2014–2018 averaged 2310.9 ± 115.7 per 1000. In the structure of morbidity, the leading places were occupied by diseases of the respiratory system – 59.2 %, the digestive system – 8.8 %, skin and subcutaneous tissue 5.5 %, trauma and poisoning – 4, 8 % and infectious and parasitic diseases. The frequency of chronic morbidity does not exceed the population estimates – 73.0 ± 4.1 per 1000. The peculiarity of chronic morbidity is the relatively high incidence of skin diseases – 25.3 % and the musculoskeletal system – 20.4 %. The morbidity of children in the first year of life is 2348.0 ± 135.1 per 1000. A feature of the morbidity structure is the high incidence of respiratory diseases, which makes up 66.3 % of the total morbidity, with population estimates – 20–30 %. Conclusion: The increased radiation background can be considered as one of the possible negative environmental factors affecting the health of the population.

scholarly journals About the role of environmental factors in carcinogenesis

2020 ◽  
Vol 169 ◽  
pp. 04003
Author(s):  
Sergey K. Pinaev ◽  
Olga G. Pinaeva ◽  
Alexey Ya. Chizhov
Keyword(s):  
Oxidative Stress ◽  
Environmental Factors ◽  
Young Children ◽  
Forest Fires ◽  
Malignant Neoplasms ◽  
The Sun ◽  
Child Population

There were found out the connections of the activity of the Sun and smoke of forest fires with the incidence of various forms of benign and malignant neoplasms in the population of young children 0-4 years old, in Khabarovsk Region, Russia. Thus, it was determined that so-called “sporadic” fluctuations in the incidence of neoplasms in the child population are not random. They are caused by long multi-year cycles of changes in the complex of environmental factors. The authors identified this phenomenon as “Alternative oncogenesis”, meaning by it the predominant occurrence of various forms of neoplasms in a certain period of time due to a change in the parameters of the complex of environmental factors. A proposed hypothesis is: ecologically linked oxidative stress as a cause of the epigenomic modulation leading to an imbalance between semaphorins and integrins that brings to oncogenesis.

scholarly journals A study of dermatoses in patients attending pediatric OPD in a tertiary care hospital of Gandhinagar, Gujarat, India

2017 ◽  
Vol 4 (2) ◽  
pp. 557
Author(s):  
Geet Gunjana ◽  
Nisha Upadhyay
Keyword(s):  
Environmental Factors ◽  
Skin Diseases ◽  
Tertiary Care ◽  
Paediatric Population ◽  
Relevant Parameter ◽  
Care Hospital ◽  
Case Record ◽  
Single Center Study ◽  
High Incidence ◽  
Male Preponderance

Background: Skin diseases in paediatric population are common all over the world. There is a wide variation in the presentation of Dermatoses in various studies. The variation among dermatoses can possibly be due to region of study, prevalent environmental factors, type of population studied, and hygiene and nutritional status and environmental factors. The objective of this study was to study prevalence, pattern of presentation and aetiologies of various dermatoses in paediatrics.Methods: A prospective, observational, single center study involving 500 patients of Dermatoses was carried out in a pediatric outpatient department. Detailed history, clinical presentation and other relevant parameter were recorded in a case record form and analyzed.Results: Majority of patients with dermatoses (39.40%) belong to age group of 6 - 16 years with male preponderance. Etiological analysis showed infections and infestations were most common dermatoses. Bacterial infection (184, 36.80%) was most common followed by viral (87, 17.40%), parasitic (51, 10.20%) and fungal (25, 5.00%) infection. Dermatitis was present in 30.6% patients. Diaper dermatitis (19 patients) was the commonest dermatitis present in infants while eczema and urticaria were the commonest dermatitis in school going children.  Pyoderma was the commonest dermatoses in this study, present in 111 patients (22.20%) followed by varicella (14.40%), impetigo (12.80%); scabies (10.20%), eczema (10.20%) and urticaria (7.60%).Conclusions: Dermatoses in children are a wide spread problem which are responsible for significant morbidity in children. The high incidence of infections and infestations are possibly due to poverty, overcrowding, undernutrition, poor hygiene and lack of health education. Skin of the young children is more prone to develop skin disease.  

Estimation of the incidence of university students studying in various courses

2020 ◽  
pp. 65-73
Author(s):  
Rofail Salykhovich Rakhmanov ◽  
Elena Sergeevna Bogomolova ◽  
Andrey Vyacheslavovich Tarasov ◽  
Aleksandr Vladimirovich Evdokimov
Keyword(s):  
Professional Training ◽  
Skin Diseases ◽  
Subcutaneous Tissue ◽  
Educational Institution ◽  
First Year ◽  
First Year Students ◽  
Youth Groups ◽  
Equal Rate ◽  
Icd 10 ◽  
Local Students

Using the example of a higher military educational institution, we conducted an analysis of the prevalence of diseases according to ICD-10 by years of study (n = 3381). Features among local students and visitors were: in long-term trends, an increase in ear diseases (more significant among visitors) and an equal rate of decrease in skin diseases and subcutaneous tissue, injuries; in the first year, significant differences in three, 2–4 courses — in two classes of diseases, in the pathogenesis of which the state of resistance of the organism is significant (some infectious and parasitic diseases, diseases of the respiratory system, skin and subcutaneous tissue); excess incidence of local first-year students and newcomers over rates in other courses, respectively, for classes 5 and 8 of diseases; differences in the incidence rate for adjacent years of study, which is important for determining the period of adaptation to the conditions of training and adaptation against the background of acclimatization. In local students, the prevalence of diseases in the first two courses was significantly higher than by 4–5 (data from the third to fifth courses did not differ), but for disease classes XI, XIII, XIX, prevalence persisted from 1–2 years, X, XII — up to 2–3 years For visiting students, the prevalence of diseases from the first to the fourth year exceeded that in the next year. For classes I, VII, VIII, XIII and XIX, the excess persisted for 1–2 years, XI — at least 3 years, X — 4 years. Research in an initially healthy team allows us to judge the process of students' adaptation to the learning environment, as well as adaptation against the background of acclimatization. Research is promising in other regions of the country; among students studying at universities of other departments. This will provide the basis for planning preventive measures in youth groups to preserve their health and improve professional training.

scholarly journals Sporothrix schenckii complex biology: environment and fungal pathogenicity

Microbiology ◽  
2014 ◽  
Vol 160 (11) ◽  
pp. 2352-2365 ◽  
Author(s):  
M. D. Téllez ◽  
A. Batista-Duharte ◽  
D. Portuondo ◽  
C. Quinello ◽  
R. Bonne-Hernández ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Subcutaneous Tissue ◽  
Sporothrix Schenckii ◽  
Aetiological Agent ◽  
Natural Habitats ◽  
Fungal Pathogenicity ◽  
Adverse Conditions ◽  
Outdoor Environments ◽  
Animal Hosts ◽  
Medical Importance

Sporothrix schenckii is a complex of various species of fungus found in soils, plants, decaying vegetables and other outdoor environments. It is the aetiological agent of sporotrichosis in humans and several animals. Humans and animals can acquire the disease through traumatic inoculation of the fungus into subcutaneous tissue. Despite the importance of sporotrichosis, it being currently regarded as an emergent disease in several countries, the factors driving its increasing medical importance are still largely unknown. There have only been a few studies addressing the influence of the environment on the virulence of these pathogens. However, recent studies have demonstrated that adverse conditions in its natural habitats can trigger the expression of different virulence factors that confer survival advantages both in animal hosts and in the environment. In this review, we provide updates on the important advances in the understanding of the biology of Spor. schenckii and the modification of its virulence linked to demonstrated or putative environmental factors.

The presence of synaptic and chromosome disjunction mutants in Cenchrus ciliaris (Poaceae: Paniceae)

Bothalia ◽  
1999 ◽  
Vol 29 (2) ◽  
pp. 327-334 ◽  
Author(s):  
N. C. Visser ◽  
J. J. Spies ◽  
H. J. T. Venter
Keyword(s):  
Environmental Factors ◽  
Geographical Distribution ◽  
High Temperatures ◽  
Chromosome Abnormality ◽  
Mutant Gene ◽  
Cenchrus Ciliaris ◽  
High Incidence ◽  
Low Humidity ◽  
Recessive Mutant ◽  
Chromosome Disjunction

Synaptic mutants are present in  Cenchrus ciliaris L This species, due to the presence of linear bivalents and occasion­al trivalents and quadrivalents, is an intermediate desynaptic species. In addition, geographical distribution and environmental factors, such as high temperatures and low humidity, could also have had an influence on the desynapsis observed.The disjunction of chromosomes during anaphase I was mostly abnormal in this desynaptic species. Precocious disjunction of chromosomes into chromatids occurred during anaphase I Due to the high incidence of this chromosome abnormality, a mutant gene,  'pc'  responsible for the disjunction of chromosomes, must be present. The absence of cytokinesis in one specimen indicates a recessive mutant gene,  'va' to be active in this species.

scholarly journals Intersectoral component of the structural and functional management model: a methodology for developing regional prevention programs and evaluating its effectiveness (for example, the child population of certain administrative regions of Ukraine)

2020 ◽  
Vol 8 (2) ◽  
pp. 53-62
Author(s):  
Oleksii Demikhov
Keyword(s):  
Primary Prevention ◽  
Environmental Factors ◽  
Quantitative Assessment ◽  
Health Indicators ◽  
Prevention Programs ◽  
Theory And Practice ◽  
Modern Theory ◽  
Qualitative And Quantitative ◽  
Child Population ◽  
The Impact

Modern ideas about comprehensive assessments of the level of health are based on synthetic (complex, integral, multidimensional) indicators, the requirement for which is the need to take into account various (by origin and methods of obtaining) health indicators both at the individual and population, regional levels. In recent years, many methodological methods have been processed to obtain a comprehensive qualitative and quantitative assessment of the state of individual health. Obtaining a generalized qualitative and quantitative assessment remains the most important methodological task of modern theory and practice of public administration and public health. The purpose of the study was to develop a methodology for substantiating intersectoral regional prevention programs and an algorithm for evaluating their effectiveness using the example of a dysplastic-dependent pathology of the bronchopulmonary system in children. In developing and justifying population-based management models for early diagnosis and primary prevention, we used systematic population modeling methods. The expected indicators of the pathogenic and sanogenic effects of the most significant regional and environmental factors of the dysplastic-dependent pathology of the bronchopulmonary system among children are determined. Substantiated models of end results for modification of risk factors and the expected effectiveness of the N-factor regional and environmental program for the primary prevention of dysplastic dependent pathology of the bronchopulmonary system in children. Priority areas for the implementation of regional-population programs for the prevention of dysplastic-dependent pathology of the bronchopulmonary system in children due to the impact on controlled environmental environmental factors are determined. An example of calculating the expected effectiveness of children's health management through interdepartmental interaction at the regional level is given. Prospects for further research on this issue related to a prospective evaluation of the effectiveness of intersectoral programs to reduce the influence of regional environmental factors on the health status of the child population, in particular, dysplastic-dependent pathology of the bronchopulmonary system.

scholarly journals SEX AND AGE CHARACTERISTICS OF RATE OF PHISICAL DEVELOPMENT OF CHILDREN OF THE NORTERN REGION WITH ESTABLISHED UNDIFFERENTIATED CONNECTIVE TISSUE DISPLASION

2021 ◽  
Vol 27 (1) ◽  
pp. 44-49
Author(s):  
Igor Andreevich Shevnin ◽  
◽  
Natalya Aleksandrovna Ilyushchenko ◽  
Olga Vasilievna Ragosina
Keyword(s):  
Environmental Factors ◽  
Connective Tissue ◽  
Physical Development ◽  
The State ◽  
Standard Of Living ◽  
State Of Health ◽  
Ecological Zones ◽  
Child Population ◽  
High Prevalence ◽  
Connective Tissue Dysplasia

The tempo characteristic of the physical development of children demonstrates the state of health of the younger generation, refl ecting the standard of living of the population in various climatic and ecological zones, as well as the infl uence of environmental factors. In view of the high prevalence of undiff erentiated forms of connective tissue dysplasia among the child population of the KhMAO – Yugra, it is necessary to study the infl uence of the dysplastic process on the processes of ontogenesis and organogenesis

Environmental Factors and Skin Diseases

1976 ◽  
Vol 141 (4) ◽  
pp. 237-243 ◽  
Author(s):  
Henry E. Jones ◽  
Charles W. Lewis ◽  
James K. Aton ◽  
Gregory W. Sorensen ◽  
William A. Akers
Keyword(s):  
Environmental Factors ◽  
Skin Diseases

Monophasic spindle cell myxoid synovial sarcoma of the hand: promising results with marginal resection

2021 ◽  
Vol 14 (1) ◽  
pp. e238366
Author(s):  
Sandeep Vijayan ◽  
Afsal P Mohammed ◽  
Mahesh Suresh Kulkarni ◽  
Sharath Kumar Rao
Keyword(s):  
Synovial Sarcoma ◽  
Elderly Woman ◽  
Spindle Cell ◽  
Normal Function ◽  
Malignant Neoplasms ◽  
High Incidence ◽  
Male Preponderance ◽  
Synovial Sarcomas ◽  
Prompt Diagnosis

Synovial sarcomas are deep-seated, genetically distinct, malignant neoplasms seen in young adults, with a male preponderance. They have unusual clinical and pathological presentation and mimic many other sarcomas and carcinomas, making the diagnosis quite challenging. Although four variants are identified, occurrence in the hand is extremely rare and leads to significant morbidity. There is a high incidence of local recurrence and distant metastasis within the first 2 years. We report the case of an elderly woman with monophasic spindle cell synovial sarcoma who presented with painless swelling in her palm and underwent local excision of the neoplasm. At 2-year follow-up, she remains totally asymptomatic with normal function of the hand. We also attempt to give an overview about monophasic spindle cell synovial sarcoma with the differentials, which would help surgeons in prompt diagnosis and appropriate management.

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