scholarly journals Influence of latent iron deficiency on cognitive abilities in students

2022 ◽  
Vol 12 (1) ◽  
pp. 117-124
Author(s):  
Ali Dani Sheikh ◽  
V. Babienko ◽  
E. Kobolev
Keyword(s):  
Iron Deficiency ◽  
Cognitive Abilities ◽  
Statistical Processing ◽  
Deficiency Anemia ◽  
National Medical ◽  
General Weakness ◽  
Latent Iron Deficiency ◽  
Medical University ◽  
The Impact ◽  
Screening Survey

The aim of the study is to assess the impact of latent iron deficiency on students' cognitive abilities. Material and methods. The study was conducted during 2018-2021 at the Department of Hygiene and Medical Ecology of Odessa National Medical University. A survey of 188 medical students aged 18-20 was conducted using a screening survey. Estimation of the qualitative content of iron compounds in the diet was performed by a calculation method using the USDA / FDA database. Persons with probable iron deficiency were examined for hemoglobin, erythrocytes, hematocrit (general clinical blood test) and serum ferritin. Additionally, the cognitive abilities of people with latent iron deficiency were assessed using MoSA, TMT, GPB, Schulte tables and TAS-20. As a control, 30 students aged 18-20 years who showed no signs of latent or overt iron deficiency were interviewed. Statistical processing was performed by methods of variance and correlation anamnesis using the software Statistica 13.0 (TIBCO, USA). Results. When evaluating diets, probable iron deficiency was identified in 69 (36.7%) students surveyed. A significant number of students reported signs of iron deficiency, namely general weakness (27 or 14.4%), increased fatigue (30 cases or 15.9%), pale skin and mucous membranes (6 or 3.2%), drowsiness (8 or 4.3%), dry mouth (11 or 5.9%), brittle hair (4 or 2.1%), bleeding gums (3 or 1.6%). In isolated cases, hyposmia, dysgeusia and dysphagia have occurred. Probable iron deficiency was found at the previous stage of the study in 29 (15.4%) patients, they subsequently underwent verifying laboratory tests. In the analysis of the obtained data, the diagnosis of mild iron deficiency anemia was confirmed in 2 (6.9%) girls. Latent iron deficiency was identified in 16 (55.2%) students, among whom girls predominated (10 people or 62.5%). Subsequent studies have shown that a significant number of students with latent iron deficiency showed moderate signs of decreased cognition. Conclusions: 1. The frequency of latent iron deficiency in the surveyed contingent was 8.5%, with an absolute predominance of girls (62.5%). 2. Latent iron deficiency in student youth can be manifested by cognitive impairment, and therefore affect academic performance. 3. The most pronounced correlation was found for ferritin content and severity of alexithymia (r = -0.61).

Role of Iron Supplementation in Reducing Severity of Depression: A Review

2020 ◽  
pp. 67-76
Author(s):  
OJS Admin
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Supplementation ◽  
Reproductive Age ◽  
Deficiency Anemia ◽  
Essential Nutrient ◽  
Severity Of Depression ◽  
The Impact ◽  
Clinical Problems

Depression is a public health disorder, ranking third after respiratory and cardiac diseases. There were many evidences that iron deficiency anemia (IDA) is one of the foremost causes regarding nutritional pointof view for depression. We reviewed these evidences that IDAlinking to depression. We identified seventeen studies in four databases including randomized-controlled trials (RCTs) and observational studies assessing the impact of IDAand iron supplementation on the risk of depression. We extracted data on the basis of sample size, geographical region, measures of depression, hemoglobin, iron levels and intake of iron supplementation and critically appraised the results from the studies. Eleven out of sixty one studies were experimental, which indicated that dietary supplementation particularly iron supplementation had an association (r − 0.19 to −0.43 and ORs 1.70–4.64) with severity of depression. Evidences showed that women of reproductive age were more vulnerable to iron deficiency anemia than other population. Low ferritin and low hemoglobin level were associated with severity of depression. Iron is an essential nutrient for all living creatures, as a cofactor of various enzymes and plays significant role in environmental stimulant for the articulation of numerous virulence factors. Many clinical problems are caused by iron deficiency. Therefore, this review intended to highlight the important role of iron supplementation in reducing the severity of depression.

scholarly journals The impact of Helicobacter pylori infection on iron deficiency anemia in pregnancy

2017 ◽  
Vol 6 (2) ◽  
pp. 60 ◽  
Author(s):  
EamanMarouf Muhammad ◽  
MiamiAbdul Hassan Ali ◽  
BanHadi Hameed ◽  
HalaHashim Hasoobe
Keyword(s):  
Helicobacter Pylori ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Helicobacter Pylori Infection ◽  
Deficiency Anemia ◽  
Anemia In Pregnancy ◽  
The Impact ◽  
In Pregnancy

scholarly journals Red Cell Distribution Width (RDW) and Hb% in the Detection of Iron Deficiency Anemia in Pregnant Women

2018 ◽  
Vol 9 (2) ◽  
pp. 137-141
Author(s):  
Gazi Sharmin Sultana ◽  
Syed Aminul Haque ◽  
Ayatunnesa ◽  
Md MA Muttalib ◽  
Md Quddusur Rahman
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Red Cell Distribution Width ◽  
Deficiency Anemia ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Latent Iron Deficiency ◽  
Automated Hematology Analyzer

Background: Detection of iron deficiency early during pregnancy is essential for correct management. Red cell distribution width (RDW) is a new routine parameter in fully automated hematology analyzer that can give the idea of early iron deficiency before Hb%. This study was aimed to see the role of red cell distribution width and Hb% in determining early iron deficiency in pregnant women.Methods: In this study 190 pregnant women were included. CBC including Hb% and RDW and iron profile were done. RDW were compared with Hb% in various stages of iron deficiency.Results: RDW was more significant than Hb level in latent iron deficiency when Hb level was normal (p<0.05). In mild and moderate iron deficiency anemia, RDW was increased progressively though Hb level was reduced. In this study RDW had sensitivity 82.3% and specificity 97.4%. Whereas Hb level had sensitivity 56.6% and specificity 90.9% for iron deficiency.Conclusion: Latent iron deficiency without other complicating disease could be screened out early by increased RDW when Hb% was normal.Anwer Khan Modern Medical College Journal Vol. 9, No. 2: Jul 2018, P 137-141

scholarly journals Associations Between Iron Deficiency Anemia and Wages in India: A Secondary Data Analysis (P22-016-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Sanchit Makkar ◽  
Sumedha Minocha ◽  
Kishor Bhat ◽  
Anjaly John ◽  
Sumathi Swaminathan ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Least Square ◽  
Sample Survey ◽  
Deficiency Anemia ◽  
Research Centre ◽  
Iron Fortification ◽  
Percentage Points ◽  
Wide Range ◽  
The Impact

Abstract Objectives Economic analyses add value beyond evidence to the implementation of any policy. The study explored the association between iron deficiency anemia (IDA) and the wages of adult men and women between 15- 49 years in India so that the possible monetary benefits of iron fortification policies could be evaluated. Methods National sample survey organization (NSSO) Employment- Unemployment data was statistically matched with the NSSO Consumer Expenditure data at an individual level for the year 2011–12. The anemia levels (assuming 50% of anemia was due to iron deficiency) was mathematically modelled in response to a wide range of nutrient intakes, including iron intake from heme and non-heme sources along with inhibitors and enhancers in the diet, adjusting for bioavailability, sanitation and menstrual losses in women. A two-stage Heckman selection model was used to establish the association between wages and IDA. In the first stage, a probit model was used to determine labour force participation and in the second stage, an ordinary least square model, corrected for sample selection bias, was used to determine the impact of IDA on wages. Results The presence of IDA resulted in a decline of 15.3 percentage points in wages of regular salaried employed men as compared to those without IDA. Similar patterns was observed for women but the impact of anemia on wages was lower in comparison to men. Among women, a decline of 8.0 percentage points was observed in the wages of regular salaried employed women compared to those without IDA. However, the presence of IDA had no significant impact on the wages of casual labourers. This indicated that there were other random factors that affected the wages of this segment of population. Conclusions There is an association between IDA and wages for a segment of working population. Addressing anemia through iron fortification programs such as the usage of double fortified salt could possibly change living standards of the population through improvement in earnings. Funding Sources International Development Research Centre, Canada; Tata Trusts, India.

scholarly journals THE IMPACT OF OBESITY ON THE COURSE OF IRON DEFICIENCY ANEMIA IN WOMEN AND ASSESSMENT OF THEIR QUALITY OF LIFE

2019 ◽  
pp. 22-28
Author(s):  
V. M. Nedoborenko ◽  
I. P. Kaidashev
Keyword(s):  
Quality Of Life ◽  
Body Mass Index ◽  
Iron Deficiency ◽  
Body Mass ◽  
Iron Deficiency Anemia ◽  
Reproductive Age ◽  
Deficiency Anemia ◽  
Control Group ◽  
The Impact

Iron deficiency anemia (IDA) is one of the causes of chronic fatigue with a decrease in the quality of life, impaired cognitive function and poor labor productivity. Obesity as a condition of chronic low-intensity inflammation is one of the factors that increases the risk of anemia and impairs the quality of life in the general population. We drew attention to the high global prevalence of anemia among pregnant women of reproductive age in the world and the prevalence of high body mass index among women compared to men in most countries. The objective of the work was to determine the impact of obesity on clinical features and quality of life of women with ІDA. We analyzed the main markers of ІDA and hematologic indices in women with obesity (n = 30) compared with the control group (n = 10), where there were women with ІDA but without obesity. It was found that there was no statistical difference between these parameters, but nevertheless, the serum ferritin level in obese women was (4.70 ± 2.68) ng/ml compared to (3.50 ± 2.93) ng/ml and had a significant positive correlation with body mass index. The analysis of the questionnaires revealed that obesity is still a significant factor in women with ІDA and obesity, which determines the decrease in quality of life mainly in the physical aspect in the absence of significant influence on the psychosocial components of health.

scholarly journals Utility of reticulocyte hemoglobin in diagnosing latent iron deficiency and iron deficiency anemia

2020 ◽  
Vol 7 (5) ◽  
pp. 1049
Author(s):  
Kavya Chandrashekar ◽  
Yashoda H. T. ◽  
Varsha Monica Reddy
Keyword(s):  
Iron Deficiency ◽  
Deficiency Anemia ◽  
Social Emotional Development ◽  
Social Emotional ◽  
Mean Values ◽  
Iron Deficient ◽  
Rbc Indices ◽  
Latent Iron Deficiency ◽  
Iron Profile ◽  
And Control

Background: Iron deficiency is the most common cause of anemia and studies have shown poor cognition, psychomotor and social/emotional development in children who are deficient in iron, even with normal hemoglobin levels, the so-called Latent phase of Iron deficiency. It is therefore crucial to identify LID, as well as IDA at the earliest stage, in order to initiate treatment.  Many tests like serum ferritin and soluble transferring receptor(sTfR) have been described collectively as a panel to detect iron deficiency; however no single test is specific enough to be used independently. Also during treatment it takes weeks to observe changes in Hb, hematocrit or RBC indices, hence the need for a more sensitive and reliable test. Objective was to evaluate effectiveness of CHr in diagnosing LID and IDA.Methods: Samples were collected from 180 children, clinically suspected to be anemic. Complete hemogram and Iron profile were measured. Three groups were defined, LID (Tfsat <20%, Hb >11g/dL; n=52), IDA (Tfsat <20%, Hb <11g/dL; (n=84) and controls (Tfsat >20%, Hb >11g/dL; n=44). The mean values of RBC indices, Iron profile and CHr was compared across the groups. A cut off value of <26 pg CHr was taken to represent Iron deficiency state.Results: Comparison between anemic group and control found that all RBC indices were found to be significantly lower including Reticulocyte hemoglobin. All of the variables in anemic group were lower compared to latent iron deficient group except MCHC and reticulocyte count. CHr was found to be statistically lower in LID and IDA group in comparison to control group.Conclusions: CHr can be used as a valuable indicator in diagnosis as well as follow-up of LID and IDA, which is easily available and inexpensive.

scholarly journals SCIENTIFIC HERITAGE AND ACHIEVEMENTS OF THE DEPARTMENT OF NORMAL PHYSIOLOGY OF DANYLO HALYTSKYI LVIV NATIONAL MEDICAL UNIVERSITY (ON THE OCCASION OF THE 125TH ANNIVERSARY OF THE DEPARTMENT)

2020 ◽  
Vol 66 (6) ◽  
pp. 104-111
Author(s):  
I.M. Kovalchuk ◽  
◽  
M.Ya. Savytska ◽  
Keyword(s):  
Cerebral Cortex ◽  
Laboratory Medicine ◽  
Sensory Function ◽  
Scientific Heritage ◽  
National Medical ◽  
Historical Outline ◽  
125Th Anniversary ◽  
The University ◽  
Medical University ◽  
The Impact

The historical outline of the Physiology Department in the Medical Faculty of Danylo Halytskyi Lviv National Medical University (LNMU) dedicated to the 125 years anniversary is presented. The department was founded by Adolf Beck at 1895. Professor Beck was not merely a scholar, with first-rate credentials for having developed methods for the study of the cerebral cortex and neurophysiology, but also a man of great personal courage. Adolf Beck also worked in fields of general physiology, such as visceral and sensory function and laboratory medicine. He also arranged a local physiological society and the Institute of Physiology of the university. He did not receive the Nobel Prize despite being nominated several times. His followers Wiktor Tychowski, Mechyslav Wierzuchowski, were next heads of Physiology Department of LNMU in the interwar time. The impact of Anatoliy Vorobjev, Yakiv Sklayrov, Eugen Panasuk in Physiology and on the development Physiology Department in second half of 20th century is presented. The modern achievement of the Lviv Physiological School is described too.

scholarly journals Cardiotoxic effect of bleomycin with a single administration in the experiment

2021 ◽  
Vol 11 (10) ◽  
pp. 242-251
Author(s):  
E. Bestanchuk ◽  
A. Gozhenko ◽  
O. Kashchenko ◽  
T. Narbutova ◽  
O. Berezovskyi ◽  
...  
Keyword(s):  
Single Injection ◽  
Statistical Processing ◽  
Myocardial Damage ◽  
Single Administration ◽  
Cardiotoxic Effect ◽  
Correlation And Regression Analysis ◽  
National Medical ◽  
Medical University ◽  
And Control ◽  
Experimental Group

The aim of the study was to evaluate the effect of a single injection of bleomycin on the heart Material and methods. The study was conducted in the Research Institute of Transport Medicine during 2016-2021. The experimental model of the cardiotoxic effect of the bleomycin was performed using the medication "Bleocin" manufactured by Nippon Kayaku Co., Ltd. (Japan). According to the task, the study was performed on 10 mature rats of both sexes of the Wistar line with a body weight of 237 ± 20 g. Rats were housed in standard vivarium conditions of Odessa National Medical University. Animals were divided into 2 groups: experimental group (n = 5) and control (n = 5). Bleomycin animals of the experimental group were obtained intraperitoneally at a dose of 0.5 IU / kg once. Withdrawal of animals from the experiment was performed on the 5th day of the experiment, followed by morphological and morphometric examination. Statistical processing of the obtained data was performed by methods of variance, correlation and regression analysis using Statistica 14.0 software (TIBCO, USA) Results. Single administration os bleomycin causes changes in macroscopic parameters (myocardial weight, visual changes) are minimal. The main changes at the microscopic level are represented by contractural degeneration with segmental and / or partial-lateral lysis, ie there is not total but partial myocardial damage. Conclusion. A single injection of bleomycin can cause inflammatory-dystrophic changes of the myocardium.

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