Development of a cell micro tensile tester and its application to investigate the mechanical properties and adhesion forces of cells.

2019 ◽  
Vol 2019 (0) ◽  
pp. J02612P
Author(s):  
Shouta OBATA ◽  
Shigeaki OHATA ◽  
Kazuaki NAGAYAMA
Keyword(s):  
Mechanical Properties ◽  
Adhesion Forces ◽  
Tensile Tester ◽  
A Cell

A Zebrafish Embryo Behaves both as a “Cortical Shell – Liquid Core” Structure and a Homogeneous Solid when Experiencing Mechanical Forces

2014 ◽  
Vol 20 (6) ◽  
pp. 1841-1847 ◽  
Author(s):  
Fei Liu ◽  
Dan Wu ◽  
Ken Chen
Keyword(s):  
Mechanical Properties ◽  
Mechanical Behavior ◽  
Zebrafish Embryo ◽  
Large Strain ◽  
Liquid Core ◽  
Small Strain ◽  
Core Structure ◽  
Mechanical Forces ◽  
Cortical Shell ◽  
A Cell

AbstractMechanical properties are vital for living cells, and various models have been developed to study the mechanical behavior of cells. However, there is debate regarding whether a cell behaves more similarly to a “cortical shell – liquid core” structure (membrane-like) or a homogeneous solid (cytoskeleton-like) when experiencing stress by mechanical forces. Unlike most experimental methods, which concern the small-strain deformation of a cell, we focused on the mechanical behavior of a cell undergoing small to large strain by conducting microinjection experiments on zebrafish embryo cells. The power law with order of 1.5 between the injection force and the injection distance indicates that the cell behaves as a homogenous solid at small-strain deformation. The linear relation between the rupture force and the microinjector radius suggests that the embryo behaves as membrane-like when subjected to large-strain deformation. We also discuss the possible reasons causing the debate by analyzing the mechanical properties of F-actin filaments.

A Nanoindentation Method for Hydrated Compliant Materials

2011 ◽  
Author(s):  
Donna M. Ebenstein
Keyword(s):  
Mechanical Properties ◽  
Soft Tissues ◽  
Adhesion Forces ◽  
Surface Detection ◽  
Heterogeneous Samples ◽  
Mineralized Tissues ◽  
Fluid Interactions

Nanoindentation is becoming an increasingly popular tool in the biomaterials field due to its ability to measure local mechanical properties in small, irregularly-shaped or heterogeneous samples.1 Although this technique was readily adapted to the study of mineralized tissues, the application of nanoindentation to compliant, hydrated biomaterials such as soft tissues and hydrogels has led to many challenges.1 Three key concerns associated with nanoindentation of compliant, hydrated materials are inaccurate surface detection, errors due to adhesion forces, and fluid interactions with the tip.1–4

scholarly journals Curing and mechanical properties of chlorosulphonated polyethylene rubber blends

2011 ◽  
Vol 17 (3) ◽  
pp. 315-321 ◽  
Author(s):  
Gordana Markovic ◽  
Vojislav Jovanovic ◽  
Suzana Samarzija-Jovanovic ◽  
Milena Marinovic-Cincovic ◽  
Jaroslava Budinski-Simendic
Keyword(s):  
Mechanical Properties ◽  
Crosslink Density ◽  
Hydraulic Press ◽  
Elongation At Break ◽  
Rubber Blends ◽  
Tensile Tester ◽  
Roll Mill ◽  
Cure Time ◽  
Chlorosulphonated Polyethylene ◽  
Scanning Electron

In this paper the curing and mechanical properties of two series of prepared blends, i.e., chlorosulphonated polyethylene (CSM)/isobutylene-co-isoprene (IIR) rubber blends and chlorosulphonated polyethylene (CSM)/chlorinated isobutylene-co-isoprene (CIIR) rubber blends were carried out. Blends were prepared using a two roll-mill at a temperature of 40-50?C. The curing was assessed by using a Monsanto Oscillating Disc Rheometer R-100. The process of vulcanization accelerated sulfur of pure rubbers and their blends was carried out in an electrically heated laboratory hydraulic press under a pressure of about 4 MPa and 160?. The stress-strain experiments were performed using tensile tester machine (Zwick 1425). Results indicate that the scorch time, ts2 and optimum cure time, tc90 increase with increasing CSM content in both blends. The values of modulus at 100% and at 300% elongation and tensile strength increases with increasing CSM content, whereas elongation at break shows a decreasing trend. The enhancement in mechanical properties was supported by data of crosslink density in these samples obtained from swelling measurement and scanning electron microscopy studies of the rubber blends fractured surfaces.

Electrospinning/Spray: The Interaction between Graphene Nanosheets and Different Nanofibers

2020 ◽  
Vol 841 ◽  
pp. 82-86
Author(s):  
Yang Zhong Chen ◽  
Han Wang ◽  
Fei Yu Fang ◽  
Hui Mei ◽  
Li Wang
Keyword(s):  
Mechanical Properties ◽  
Surface Morphology ◽  
Mechanical Test ◽  
Graphene Nanosheets ◽  
Strain Sensors ◽  
Synergic Effect ◽  
Electrospun Nanofiber ◽  
Promising Candidate ◽  
Tensile Tester ◽  
Morphology And Mechanical Properties

The electrospun nanofiber/graphene composites is a promising candidate in the field of flexible strain sensors due to the synergic effect of graphene and the nanofibers. It is an effective way to synthesize a uniform graphene-embedded film by simultaneously electrospinning nanofibers and electrospraying graphene nanosheets. In this paper, we prepare two specimens of different materials to study the interaction between graphene nanosheets and nanofibers under the same process parameters, such as thermoplastic urethane (TPU), polyacrylonitrile (PAN). Then, morphology and mechanical properties are used to characterize the interaction. The mechanical test was conducted by the tensile tester, and the surface morphology of electrospun nanofibrous films was observed through a microscope. By comparing these results, the properties of the graphene nanosheets embedded to different nanofibers are explored. This study provides a good way to select an appropriate nanofiber matrix for the application in flexible strain sensors.

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