scholarly journals The correlation between spinal and chest wall deformities and pulmonary function in Marfan syndrome

2020 ◽  
Vol 14 (4) ◽  
pp. 343-348
Author(s):  
Hila Otremski ◽  
Roger F. Widmann ◽  
Mary F. Di Maio ◽  
Dror Ovadia

Purpose Scoliosis, chest wall deformities and pulmonary involvement are common features of Marfan syndrome (MFS). We aimed to assess the impact of spinal and chest wall deformities on pulmonary function in paediatric MFS patients with a surgically managed spinal deformity. Methods In this multicentre retrospective study, spirometry, lung volumes and radiographic imaging were performed on 26 MFS patients between the ages of seven and 18 years who were undergoing planned spinal fusion surgery for spinal deformity. A correlation analysis assessed the relationship between radiographic measurements of spinal and chest wall deformities and predicted total lung capacity (TLC), forced vital capacity (FVC) and the ratio between forced expiratory volume in one second and FVC (FEV1/FVC). Results In total, 18 patients (70%) had impaired pulmonary function. Thoracic kyphosis (mean 19.3°; -32° to 54°) had a strong positive correlation with FEV1/FVC (r = 0.65; p < 0.001). Significant decrease in FEV1/FVC below 80% occurred at kyphosis under 15° (p = 0.004). Kyphosis had a moderate negative correlation with FVC (r = -0.43; p = 0.03). Chest wall deformity had a strong negative correlation with FEV1/FVC (r = -0.61; p = 0.001). The magnitude of the thoracic curve (mean 55.2°; 28° to 92°) had a significant moderate negative correlation with TLC (r = -0.45; p = 0.04). Conclusion In MFS, three factors correlate with decreased pulmonary function measures: hypokyphosis, increasing chest wall deformity and increasing coronal curve magnitude. Hypokyphosis and increased chest wall deformity correlated with diminished FEV1/FVC; increasing thoracic spinal curvature with diminished TLC. Further analysis with a larger cohort will help better define the relationship between these deformities and pulmonary function in this unique population. Level of Evidence IV

2021 ◽  
pp. 1-9
Author(s):  
Sara Liguori ◽  
Antimo Moretti ◽  
Angela Palomba ◽  
Marco Paoletta ◽  
Francesca Gimigliano ◽  
...  

BACKGROUND: In patients with Parkinson disease (PD), severe postural and gait impairments are rarely observed in early stage of disease and non-motor symptoms (NMS) are often overlooked. OBJECTIVE: This observational study aimed to characterize the impact of non-motor impairments on walking kinematics in early stages PD patients, and to assess the differences of gait parameters and NMS between PD patients with and without mild cognitive impairment (MCI). METHODS: Twenty-six patients with Modified Hoehn and Yahr Scale score≤2 were evaluated for NMS using Kings Parkinson’s Pain Scale, Parkinson Fatigue Severity scale, Parkinson Anxiety Scale, Beck Depression Inventory and Epworth Sleepiness Scale, kinematic parameters through an inertial sensor and cognitive performance by a comprehensive neuropsychological battery. RESULTS: Fatigue had a moderate negative correlation with step cadence, and a moderate to strong positive correlation with gait duration, Timed Up and Go (TUG) and TUG Dual Task (p <  0.01). Pain showed positive moderate correlation with gait duration (p <  0.01). Twelve patients resulted affected by MCI and reported significantly worse scores in gait duration, pain and fatigue (p <  0.05). According to cognitive z scores, PD-MCI group showed a moderate negative correlation between visuospatial abilities and fatigue (p <  0.05). CONCLUSIONS: NMS significantly affect walking kinematics whereas a limited role of cognitive status on motor performance occur in the early PD stages.


2015 ◽  
Vol 2015 ◽  
pp. 1-15 ◽  
Author(s):  
Gang Lin ◽  
Jingying Fu ◽  
Dong Jiang ◽  
Jianhua Wang ◽  
Qiao Wang ◽  
...  

Epidemiological studies around the world have reported that fine particulate matter (PM2.5) is closely associated with human health. The distribution of PM2.5concentrations is influenced by multiple geographic and socioeconomic factors. Using a remote-sensing-derived PM2.5dataset, this paper explores the relationship between PM2.5concentrations and meteorological parameters and their spatial variance in China for the period 2001–2010. The spatial variations of the relationships between the annual average PM2.5, the annual average precipitation (AAP), and the annual average temperature (AAT) were evaluated using the Geographically Weighted Regression (GWR) model. The results indicated that PM2.5had a strong and stable correlation with meteorological parameters. In particular, PM2.5had a negative correlation with precipitation and a positive correlation with temperature. In addition, the relationship between the variables changed over space, and the strong negative correlation between PM2.5and the AAP mainly appeared in the warm temperate semihumid region and northern subtropical humid region in 2001 and 2010, with some localized differences. The strong positive correlation between the PM2.5and the AAT mainly occurred in the mid-temperate semiarid region, the humid, semihumid, and semiarid warm temperate regions, and the northern subtropical humid region in 2001 and 2010.


Author(s):  
Z. Sh. Pavlova ◽  
V. Yu. Grevina

Introduction. Today, there are not enough studies demonstrating the relationship between body composition disorders in men with excess adipose tissue and metabolic syndrome (MS), depending on the content of testosterone, estradiol, sex hormone binding globulin (SHBG), anthropometric parameters, or blood pressure (BP).Aim: to study the relationship between disturbances in anthropometric parameters, the level of sex hormones and BP in men with MS.Materials and Methods. The study included 64 overweight men. The patients were divided into 3 groups depending on the body mass index (BMI): group 1 with overweight (n = 24), group 2 with the first degree of obesity (n = 21), group 3 with the second and third degrees of obesity (n = 19). A correlation analysis was carried out between the results of bioimpedance analysis (BIA) and laboratory data, and the level of difference between the groups under consideration was determined.Results. The relationship was revealed between the parameters of body composition in men with overdeveloped adipose tissue and MS, depending on the level of testosterone, estradiol, SHBG, anthropometric parameters and blood pressure indicators. A moderate negative correlation was observed across the sample between the testosterone level and a number of anthropometric indicators: waist circumference (WC), OT/hip circumference (HC) and BMI (p < 0.05). A weak negative correlation was found between the level of testosterone, fat mass (FM) and the proportion of FM in the general sample. A weak negative correlation between SBP and testosterone across the sample found, while in group 3 – a moderate negative correlation. A positive weak correlation was found between testosterone and estradiol in the general sample and in group 2. In group 1, this correlation is moderately positive and in t group 3 – a negative weak correlation. A positive correlation can be traced between testosterone and SHBG: moderate in the entire sample, in groups 1 and 2, and noticeable in group 3.Conclusion. The relationship was revealed between the parameters of body composition in men with excess adipose tissue and MS, depending on the content of testosterone, estradiol, SHBG, anthropometric parameters and ВР. This confirms the consistency and multicomponent nature of the obesity problem.


2019 ◽  
Vol 8 (4) ◽  
pp. 6709-6711

The objective of this study is to examine the relationship between the board size and firm performance of Shariah-Compliant companies in Malaysia. The characteristics of the board of Shariah-compliant companies in Consumer Products counter of Bursa Malaysia are being examined against the firm’s performance using data from 77 companies from year 2014 to 2016. Based on the result of regression, board size has a strong positive correlation with the performance of the firms. This study suggests that Shariah-Compliant Companies need to strengthen the Shariah governance to produce products that Muslim consumer use in their daily lives. The appointment of director with Shariah background must be highly encouraged if not mandatory to companies involved in producing food, drinks, pharmaceutical and cosmetics in order for the companies to tap their expertise in enhancing halal governance. The findings of the study would be very useful to the regulators to improve the Malaysian Code of Corporate Governance. Furthermore, the findings of the study also help to fill the gap on scarce of literatures that study the relationship between the corporate governance practices and performance.


Author(s):  
Elham Ezeldeen Hassan, Naamat Muhammad Saeed

The study dealt with the relationship of electronic service and electronic pricing in attracting customers by applying to the Sudanese banking sector The problem of the study lies in identifying the relationship between electronic service and electronic pricing in attracting customers by identifying the quality of the correlation between electronic service and electronic pricing and attracting customers and the importance of the study stemmed from The big role that banks play in providing financial services in Sudan and through information and data and analyzing them to benefit from them, and the main goal of this study is to try to reveal the impact of electronic marketing My clients in the bank attract, the study seeks to test the following hypotheses of the study, there is a strong positive correlation with statistical function between the electronic service and attract customers, and there is a positive correlation relationship with a medium statistical function between the electronic pricing and attract customers. The study followed the historical approach, deductive approach, descriptive approach and inductive approach, the study reached a number of results, the most important of which is that providing good electronic service is no longer optional or a set of slogans and methods of advertising but rather has become a reality imposed by the nature of conditions and variables in the contemporary business environment as imposed by the nature and characteristics of clients themselves, the basis To achieve success, growth and continuity in the market depends on the presence of a customer base and the strengthening of the relationship between customers and the bank, and one of the most important recommendations recommended by the study is the establishment of sections for electronic banking services in the bank’s branches and the establishment of an ester Tejah marketing is working to attract more of both cases, customers continuity in the creation of the bank's branches and improve the work, the use of modern software in the electronic service to keep pace with technological developments, taking into account security and safety in the payment of the amounts of buying and selling via computer networks because of concerns arising from the possibility of interception and theft.


2015 ◽  
Vol 15 (2) ◽  
pp. 2055-2084 ◽  
Author(s):  
H. Liang ◽  
Z. M. Chen ◽  
D. Huang ◽  
Q. Q. Wu ◽  
L. B. Huang

Abstract. The existence and importance of peroxyformic acid (PFA) in the atmosphere has been under controversy. We present here, for the first time, the observation data for PFA from four field measurements carried out in China. These data provided powerful evidence that PFA can stay in the atmosphere, typically in dozens of pptv level. The relationship between PFA and other detected peroxides was examined. The results showed that PFA had a strong positive correlation with its homolog, peroxyacetic acid, due to their similar sources and sinks. Through an evaluation of PFA production and removal rates, we proposed that the reactions between peroxyformyl radical (HC(O)O2) and formaldehyde or the hydroperoxyl radical (HO2) were likely to be the major source and degradation into formic acid (FA) was likely to be the major sink for PFA. Based on a box model evaluation, we proposed that the HC(O)O2 and PFA chemistry was a major source for FA under low NOx conditions. Furthermore, it is found that the impact of the HC(O)O2 and PFA chemistry on radical cycling was dependent on the yield of HC(O)O2 radical from HC(O) + O2 reaction. When this yield exceeded 50%, the HC(O)O2 and PFA chemistry should not be neglected for calculating the radical budget. To make clear the exact importance of HC(O)O2 and PFA chemistry in the atmosphere, further kinetic, field and modeling studies are required.


Land ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 915
Author(s):  
Ziqi Zhou ◽  
Yung Yau

Despite its informal nature, small property rights housing (SPRH) proliferates in many Chinese cities. Given the institutional functions of the SPRH institution, it may not be desirable for the state to intervene in the SPRH sector. However, the institutional credibility and the institutional functions of SPRH are not completely endogenous, which contradicts the assumption of the credibility thesis. Based on the framework of the credibility thesis, this paper proposes the concept of the substitutability of institutional functions and develops a framework integrating the concepts of substitutability and credibility to examine the influence of functional substitutability on institutional credibility. Research hypotheses were tested with the data collected through a questionnaire survey on SPRH residents in Shenzhen and Chenzhou (n = 458). The analysis results of the combined model suggest that the supportive perceptions of actors for SPRH and the credibility of SPRH are significantly related to the substitutability of SPRH’s functions. The effect of the substitutability of social housing on credibility is found insignificant, while the impact of the substitutability of commercial housing on credibility is significant. However, the analysis results are city-specific. A significant negative correlation is found between the substitutability of formal housing institutions and the credibility of SPRH in Chenzhou but not in Shenzhen. This study attempted to refine the credibility thesis by clarifying the relationship between institutional functions and institutional credibility and examining the endogeneity of credibility.


Author(s):  
J. Karzis ◽  
E.F. Donkin ◽  
I.M. Petzer

The length of the antibiotic withdrawal period after intramammary treatment was influenced by the milk yield of dairy goats during this trial. Shorter withdrawal periods were seen in relatively high yielding dairy goats (production above 1.5 ℓ per day) compared to low producers (less than 1.3 ℓ per day). High yielding goats treated with Curaclox LC (Norbrook [Pharmacia AH]) had a withdrawal period of 42 h, while low yielding goats, treated with the same product, had a withdrawal period of 74 h. The recommended withdrawal period for Curaclox LC for use in cattle is 72 h. Relatively high yielding goats treated with Rilexine 200 LC (Logos Agvet [Virbac]) had a significantly shorter withdrawal period (37 h) than that recommended for use in cattle (96 h). Low yielding goats treated with Spectrazol Milking Cow (Schering-Plough Animal Health) had a significantly longer (95 h) withdrawal period than that recommended for use in cattle (60 h). Withdrawal periods were also influenced by stage of lactation and parity. There was a moderate positive correlation between lactation number and withdrawal period, as measured by TRIS (R2 = 0.621), and a moderate negative correlation between stage of lactation and withdrawal period (R2 = -0.669). In Trials 1, 2 and 3 combined there was a moderate negative correlation between withdrawal period and volume (R2 = -0.511) and a strong positive correlation between withdrawal period and lactation number (R2 = 0.720). The differences in percentage milk fat, protein and lactose before, during and after treatment were not statistically significant except in Trial 3 (Curaclox LC and Rilexine 200 LC) where protein and lactose differed significantly. In Trial 2 (Spectrazol Milking Cow) milk fat percentages differed significantly between treatment and control groups as did protein percentages in Trial 3. These differences are however, not biologically meaningful.


2021 ◽  
Vol 18 (2) ◽  
pp. 207-222
Author(s):  
Laike Yang ◽  
Bo Xu

To contain the COVID-19 pandemic, medical products play an important role around the world. This paper studies the relationship between trade and pandemic control by testing the impact of importing medical products from China on COVID-19 cases and deaths. Using a fixed-effects model, we find that there is a significant negative correlation between imports of medical products from China and COVID-19 cases; for every 1 percent increase in protection equipment imported from China, new COVID-19 cases per day drop by 0.24 percent, and COVID-19-related deaths decrease by 0.13 percent in two weeks. The evidence suggests that trade can play a vital role in fighting the pandemic.


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