The Definition of Risk Groups for the Electricity Network Objects in their Future Intellectualization

2015 ◽  
Vol 5 (1) ◽  
pp. 9-17
Author(s):  
Pavel V. Gluschenko ◽  
Keyword(s):  
Risk Groups ◽  
Electricity Network ◽  
Definition Of

Pocket memo based on the ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma: definition of prognostic risk groups

2021 ◽  
pp. ijgc-2021-003110
Author(s):  
Manon Christiane Daix ◽  
Laurence Gladieff ◽  
Alejandra Martinez ◽  
Gwenael Ferron ◽  
Martina Aida Angeles
Keyword(s):  
Endometrial Carcinoma ◽  
Risk Groups ◽  
Definition Of

The logistical management of tertiary urethral disease in the United Kingdom: Implications from an online audit of male reconstructive urethral surgery

2020 ◽  
Vol 13 (4) ◽  
pp. 288-294
Author(s):  
Stephen R Payne ◽  
Sarah Fowler ◽  
Anthony R Mundy ◽  
A. Alhasso ◽  
Y. Almallah ◽  
...  
Keyword(s):  
High Volume ◽  
Risk Groups ◽  
Outcome Data ◽  
Urethral Reconstruction ◽  
Level Of Evidence ◽  
The United Kingdom ◽  
Surgical Complexity ◽  
Volume Outcome ◽  
Definition Of ◽  
The Uk

Objective: To determine those patient groupings, based on volume and risk, whose optimal urethral reconstructive management might be provided by a reorganisation of UK reconstructive surgeons. Methods: Between 2010 and 2017, ~689 men/year were enrolled onto an online audit platform collecting data about urethral reconstruction in the UK; this accrual was compared against hospital episode statistics (HES). The available workforce, and where this was based, was collected. Individual and institutional incumbent patient volumes, pathology, surgical complexity and outcomes from treatment were collated to stratify volume/risk groups. Results: More than 90% of all HES-recorded data were accrued, being provided by 50 surgeons at 39 operative sites. Most reconstructive surgery was provided at 10 centres performing >20 procedures/year. More than 50% of all interventions were of a high-volume low-risk type. Of activity, 32.3% was intermediate volume or moderate risk, and 12.5% of men presented for lower-volume or higher-risk procedures. Conclusion: Correlation of detailed volume/outcome data allows the definition of patient populations presenting for urethral reconstruction. Stratification of each group’s management, to optimise the surgical outcome, may be applied to a hierarchical service delivery model based on the complexity of the patient’s presenting urethral pathology. Level of evidence: Level IV

scholarly journals The case for expanding the definition of ‘key populations’ to include high-risk groups in the general population to improve targeted HIV prevention efforts

2015 ◽  
Vol 105 (8) ◽  
pp. 664 ◽  
Author(s):  
Olive Shisana ◽  
Numpumelelo Zungu ◽  
Meredith Evans ◽  
Kathryn Risher ◽  
Thomas Rehle ◽  
...  
Keyword(s):  
High Risk ◽  
General Population ◽  
Hiv Prevention ◽  
Risk Groups ◽  
Key Populations ◽  
Definition Of

The Frequency of Genetic Anomalies According to Clonal Plasma Cells' Phenotype in Patients with Newly Diagnosed (ND) Multiple Myeloma (MM)

Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 5316-5316
Author(s):  
Andrei Garifullin ◽  
Irina Martynkevich ◽  
Sergei Voloshin ◽  
Alexei Kuvshinov ◽  
Ludmila Martynenko ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Plasma Cells ◽  
Conflicts Of Interest ◽  
Risk Group ◽  
Risk Groups ◽  
Fish Analysis ◽  
Newly Diagnosed ◽  
Definition Of ◽  
Standard Risk

Abstract Background. Genetic anomalies (GA) are primary link of pathogenesis in MM. GA lead to formation of clonal plasma cells, which has different phenotype. Aim. To estimate the incidence of GA and their correlation with clonal plasma cells' phenotype in patients with ND MM. Methods. We analysed 22 patients with ND MM (median age 57 years, range 38-80; male/female - 1:1.75). Cytogenetic analysis was performed on bone marrow samples using standard GTG-method. Metaphase FISH analysis was performed according to the manufacturer's protocol using DNA probes: LSI 13(RB1)13q14, IGH/CCND1, IGH/FGFR3, LSI TP53 (17q13.1). 8-color immunophenotypic by flow cytometry using antibody to CD45, CD38, CD138, CD56, CD19, CD20, CD27 and CD117 antigenes. Results. Translocation t(11;14) was detected in 3/14 (21.4%) patients, del(13q) - 2/14 (14.3%), t(11;14) - 3/14 (21.4%), hypodyploidy - 1/20 (5%), del(17р) - 0% patients. Clonal plasma cells' phenotype CD38+CD138+CD45- was detected in 100%. Expression CD56+ was revealed in 11/22 (50%) patients, CD19+ in 9/22 (40.9%), CD117+ in 5/22 (22.7%), CD20+ in 1/22 (4.5%), CD27+ in 1/22 (4.5%). The frequency of GA didn't depend on clonal plasma cells' phenotype and was 27.3%(3/11) in CD56+ phenotype, 23.8%(5/21) - CD20-, 23.8%(5/21) - CD27-, 23.5%(4/17) - CD117-, 23%(3/13) - CD19-, 22.2%(2/9) - CD19+, 20%(1/5) - CD117+, 18.2%(2/11) - CD56-, 0%(0/1) - CD20+, 0%(0/1) - in CD27+ phenotype. Patients of standard risk group according to mSMART 2.0 with GA had CD19-negative plasma cells' phenotype vs. CD19-positive phenotype in patients of intermediate and high-risk groups (p<0.05). 3-years overall survival in standard risk group with CD19- phenotype was 92,3%, CD19+ - 77,7% (p>0.05). Conclusion . Identification of GA, which has adverse forecast, correlates with CD19+ plasma cells phenotype. The combined definition of plasma cells phenotype and GA can improve the system of risk stratification in MM. Disclosures No relevant conflicts of interest to declare.

The cost of health care for HIV-positive patients

1997 ◽  
Vol 8 (1) ◽  
pp. 50-53 ◽  
Author(s):  
R P Brettle ◽  
F I Atkinson ◽  
J Wilcock ◽  
A Richardson ◽  
R Lewis ◽  
...  
Keyword(s):  
Health Care ◽  
Care Service ◽  
Health Care Service ◽  
Hospital Costs ◽  
Risk Groups ◽  
Clinical Staging ◽  
Service Activity ◽  
Comprehensive Health ◽  
Definition Of ◽  
A Prospective Study

Utilizing a prospective study of health service activity for HIV/AIDS, 2 estimates of hospital costs of care analysed with reference to gender, risk activity, immunological and clinical staging (1987 definition of AIDS) were undertaken. Utilizing combined costs per life year (based on hospital and hospice activity but not primary and community care) the ratio of costs for CD4< 200 and cd4> 200 was for most risk groups between 2-5 : 1 whilst for AIDS : pre-AIDS it was between 3.6-8.3 : 1 except for homosexuals where it was 12.6 : 1. A comparison of the standard hospital costs for infectious diseases with the published accounts for clinical AIDS care in Lothian suggests a 3-4-fold underestimate in the costs of providing a comprehensive health care service.

scholarly journals Antenatal hydronephrosis: a five-year retrospective study

2021 ◽  
Vol 35 (3) ◽  
Author(s):  
Maria Gaia ◽  
◽  
Mariana Capela ◽  
Margarida Peixoto ◽  
Joana Borges ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Kidney Injury ◽  
Risk Groups ◽  
Mean Value ◽  
Third Trimester ◽  
Antenatal Hydronephrosis ◽  
Male Predominance ◽  
Wide Range ◽  
Definition Of

Introduction: Antenatal hydronephrosis (ANH) is common in fetal ultrasounds. Though mostly transient, it can be associated with congenital abnormalities and kidney injury. The authors went to assess the evolution of children with ANH and identify risk groups. Methods: Retrospective cohort study of children with ANH from 2013‑2017. Renal pelvis anteroposterior diameter (APD) of 4 and 7mm or more in the second and third trimester, respectively, defined diagnosis of ANH. APD also defined severity stratification. The primary out‑ comes included occurrence of urinary tract infection (UTI) and congenital anomalies of the kidney and urinary tract (CAKUT). Results: We identified 198 cases, with male predominance (76.8%) and a 2.1% incidence. It resolved antenatally in 12.1%, with a lower mean value of APD in these cases (p=0.017), and persisted in 43.4%. CAKUT were found in 8.6% of the patients. At least 1 episode of UTI occurred in 9.1% of patients during follow‑up. The degree of ANH in the 3rd trimester was related to postnatal persistence and degree (p<0.001) and the postnatal degree was related to the occurrence of UTI (p=0.008). The 3rd trimester and postnatal degree were also associated to the presence of CAKUT (p=0.036; p=0.001), although not with vesicoureteral reflux (VUR). The persistence of ANH through the 2nd and 3rd trimester was related to postnatal persistence (p=0.002) and degree (p=0.007), and the presence of CAKUT excluding VUR (p=0.034). The optimal cut‑off for the APD in the 3rd trimester to predict the occurrence of negative outcomes (CAKUT and/or UTI), through a receiver operating characteristic (ROC) curve, was 8.225mm with 76% sensitivity and 59% specificity. Discussion: ANH is frequent and reflects a wide range of conditions, requiring follow‑up. Most cases resolve spontaneously and require no further intervention other than ultrasounds. 3rd trimester and postnatal degree are related to prognosis, allowing the definition of risk groups and the improvement of patient management.

169 Definition of risk groups for PSA failure after radical prostatectomy - tumour volume or multivariate analysis?

2004 ◽  
Vol 3 (2) ◽  
pp. 45
Author(s):  
M. Alschibaja ◽  
C. Mueller ◽  
J. Massmann ◽  
A. Funk ◽  
R. Hartung ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Radical Prostatectomy ◽  
Risk Groups ◽  
Tumour Volume ◽  
Psa Failure ◽  
Definition Of

scholarly journals Epidemiological diagnosis of infections associated with provision of medical care at current state

2020 ◽  
Vol 3 (32) ◽  
pp. 5-10
Author(s):  
O. A. Orlova ◽  
A. V. Tutelyan ◽  
M. N. Zamyatin ◽  
V. G. Akimkin
Keyword(s):  
Risk Factors ◽  
Medical Care ◽  
General System ◽  
Risk Groups ◽  
Risk Identification ◽  
Epidemiological Surveillance ◽  
Medical Organization ◽  
Head Nurse ◽  
Prevention Of Infections ◽  
Definition Of

The risk-based approach to the prevention of healthcare-associated infections (HAIs) is entirely based on the results of a well-organized epidemiological diagnosis, which is aimed primarily at identifying risk factors. The structure of the risk-based approach includes risk identification, risk identification and risk analysis. One of the important points of epidemiological diagnosis is epidemiological observation. For the organization of epidemiological surveillance, both passive and active methods are used. The active method is the most effective, since it is an active search and identification of cases of HAIs using the standard definition of cases and the results of laboratory examination of patients from risk groups. To organize such work, a commission is formed in each medical organization, which should include an epidemiologist, clinical pharmacologist, expert doctor, laboratory assistant, head nurse, and a pharmacy employee. The functions of each participant depend on the organization of the general system for identifying HAIs in this organization. The proposed model of a risk-based approach to the epidemiological diagnosis of HAIs allows timely identification of groups and risk factors both in the context of individual departments and the medical organization as a whole, and, accordingly, to develop effective measures for the prevention of infections associated with the provision of medical care.

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