Non-enzymatic glucose detection using nitrogen-doped diamond-like carbon electrodes modified with gold nanoclusters

2010 ◽  
Vol 82 (11) ◽  
pp. 2217-2229 ◽  
Author(s):  
Aiping Liu ◽  
Erjia Liu ◽  
Guocheng Yang ◽  
Nay Win Khun ◽  
Wenguang Ma
Keyword(s):  
Photoelectron Spectroscopy ◽  
Gold Nanoclusters ◽  
High Sensitivity ◽  
Vacuum Arc ◽  
Diabetic Patients ◽  
Diamond Like Carbon ◽  
Glucose Detection ◽  
Detection Range ◽  
Nitrogen Doped ◽  
Glucose Levels

Highly sensitive electrochemical electrodes for glucose detection were developed by using Au nanoclusters (NCs) to modify nitrogen-doped diamond-like carbon thin films (DLC:N/Au). The DLC:N/Au electrodes were prepared with a filtered cathodic vacuum arc process followed by electrodeposition and characterized by X-ray photoelectron spectroscopy, Raman spectroscopy, and scanning electron microscopy. The size of the Au NCs covered by Au oxide ranged between 10 and 70 nm with a density of 108–109 clusters per cm2. Glucose oxidation at the DLC:N/Au electrodes started from about –0.5 V due to the high catalytic activities of the Au NCs in NaOH solutions, and the catalytic ability of the electrodes depended on the amount of Au NCs deposited on the electrode surfaces. A linear detection range of glucose with the DLC:N/Au electrodes was identified from about 0.25 to 30 mM (covering blood glucose levels in diabetic patients) with a detection limit of 60 μM. The experimental results showed that the non-enzymatic glucose sensors based on the DLC:N/Au electrodes had high sensitivity and good reproducibility and stability.

Field emission properties of nitrogen-doped diamond-like carbon films deposited by direct metal ion beam deposition

2001 ◽  
Vol 697 ◽  
Author(s):  
Kie Moon Song ◽  
Namwoong Paik ◽  
Steven Kim ◽  
Daeil Kim ◽  
Seongjin Kim ◽  
...  
Keyword(s):  
Field Emission ◽  
Photoelectron Spectroscopy ◽  
Metal Ion ◽  
Nitrogen Doping ◽  
Ion Beam ◽  
Diamond Like Carbon ◽  
Emission Data ◽  
Nitrogen Doped ◽  
Ion Beam Deposition ◽  
Beam Deposition

AbstractNitrogen-doped diamond-like carbon (DLC) films were deposited on a silicon substrate by direct metal ion beam deposition (DMIBD). Partial pressures of nitrogen gas were changed to get different compositions of nitrogen in the DLC films. The composition and surface morphology of the films were examined using X-ray photoelectron spectroscopy (XPS) and atomic force microscope (AFM). Effect of nitrogen doping on field emission property was studied. The field emission data indicated that the nitrogen doping lowered the turn-on field and increase the current density. It was believed that doping of nitrogen into the DLC film plays an important role in enhancement of the field emission. This enhancement of field emission could be explained by the improvement of electron transport through nitrogen-dope DLC layer.

Self-supported Ni nanoparticles embedded on nitrogen-doped carbon derived from nickel polyphthalocyanine for high-performance non-enzymatic glucose detection

2018 ◽  
Vol 6 (42) ◽  
pp. 6781-6787 ◽  
Author(s):  
Wenbin Gao ◽  
Qin Li ◽  
Meiling Dou ◽  
Zhengping Zhang ◽  
Feng Wang
Keyword(s):  
High Performance ◽  
High Sensitivity ◽  
Glucose Detection ◽  
Ni Nanoparticles ◽  
Nitrogen Doped ◽  
Nitrogen Doped Carbon ◽  
Supported Ni

Ni nanoparticles self-supported on N-doped carbon derived from nickel-polyphthalocyanine exhibit a high sensitivity and long-term reusability for glucose detection.

scholarly journals A Smart Tongue Depressor-Based Biosensor for Glucose

Sensors ◽  
2019 ◽  
Vol 19 (18) ◽  
pp. 3864 ◽  
Author(s):  
Xiaojin Luo ◽  
Weihua Shi ◽  
Yiqun Liu ◽  
Pengju Sha ◽  
Yanan Chu ◽  
...  
Keyword(s):  
Electronic Materials ◽  
Silver Chloride ◽  
Close Contact ◽  
Human Saliva ◽  
Diabetic Patients ◽  
Glucose Detection ◽  
Healthcare Applications ◽  
Counter Electrodes ◽  
Detection Range ◽  
Tongue Depressor

The development of new bioelectronic platforms for direct interactions with oral fluid could open up significant opportunities for healthcare monitoring. A tongue depressor is a widely used medical tool that is inserted into the mouth, where it comes into close contact with saliva. Glucose is a typical salivary biomarker. Herein, we report—for the first time—a tongue depressor-based biosensor for the detection of glucose in both phosphate buffer and real human saliva. Carbon nanotubes (CNTs) are attractive electronic materials, with excellent electrochemical properties. The sensor is constructed by printing CNTs and silver/silver chloride (Ag/AgCl) to form three electrodes in an electrochemical cell: Working, reference, and counter electrodes. The enzyme glucose oxidase (GOD) is immobilized on the working electrode. The glucose detection performance of the sensor is excellent, with a detection range of 7.3 μM to 6 mM. The glucose detection time is about 3 min. The discretion between healthy people’s and simulated diabetic patients’ salivary samples is clear and easy to tell. We anticipate that the biosensor could open up new opportunities for the monitoring of salivary biomarkers and advance healthcare applications.

The Biocompatibility of Ti Alloy Improved by Nitrogen-Doped Diamond-Like Carbon Films

2014 ◽  
Vol 711 ◽  
pp. 250-254 ◽  
Author(s):  
Wufanbieke Baheti ◽  
Ming Xin Li ◽  
Fu Guo Wang ◽  
Jin Ge Song ◽  
Long Hua Xu ◽  
...  
Keyword(s):  
Contact Angle ◽  
Photoelectron Spectroscopy ◽  
Carbon Film ◽  
Chemical Vapor ◽  
Carbon Films ◽  
Diamond Like Carbon ◽  
Measuring Device ◽  
Nitrogen Doped ◽  
Angle Measuring ◽  
N Doping

The nitrogen-doped diamond-like carbon film was prepared on Ti6Al4V alloy by using plasma enhanced chemical vapor deposition (PECVD) technique,and its biocompatibility was studied.The surface morphology,chemical composition and contact angle were measured by scanning electron microscope (SEM),X-ray photoelectron spectroscopy(XPS),Raman Spectrometer and contact angle measuring device. Finally, the proliferation rate and cellular morphology of 3T3-E1 osteoblast cells on different sample surfaces were tested and Image J software was used to statistically analyze the count of the adhered cells. The results showed that cell adhesion and proliferation were significantly (P<0.05) increased on nitrogen-doped diamond-like carbon films , which illustrated that N doping improved the biocompatibility of DLC films. This finding has potential clinical application value to modify titanium alloy for new bone formation.

Diamond-Like Carbon Films for Silicon Passivation in Microelectromechanical Devices

1995 ◽  
Vol 383 ◽  
Author(s):  
M. R. Houston ◽  
R. T. Howe ◽  
K Komvopoulos ◽  
R. Maboudian
Keyword(s):  
Contact Angle ◽  
Surface Properties ◽  
Photoelectron Spectroscopy ◽  
Microelectromechanical Systems ◽  
Adhesion Force ◽  
Contact Angles ◽  
Vacuum Arc ◽  
Diamond Like Carbon ◽  
Adhesion Forces ◽  
Water Contact

ABSTRACTThe surface properties of diamond-like carbon (DLC) films deposited by a vacuum arc technique on smooth silicon wafers are presented with specific emphasis given to stiction reduction in microelectromechanical systems (MEMS). The low deposition temperatures afforded by the vacuum arc technique should allow for easy integration of the DLC films into the current fabrication process of typical surface micromachines by means of a standard lift-off processing technique. Using X-ray photoelectron spectroscopy (XPS), contact angle analysis, and atomic force microscopy (AFM), the surface chemistry, microroughness, hydrophobicity, and adhesion forces of DLC-coated Si(100) surfaces were measured and correlated to the measured water contact angles. DLC films were found to be extremely smooth and possess a water contact angle of 87°, which roughly corresponds to a surface energy of 22 mJ/m2. It is shown that the pull-off forces measured by AFM correlate well with the predicted capillary forces. Pull-off forces are reduced on DLC surfaces by about a factor of five compared to 10 nN pull-off forces measured on the RCA-cleaned silicon surfaces. In the absence of meniscus forces, the overall adhesion force is expected to decrease by over an order of magnitude to the van der Waals attractive force present between two DLC-coated surfaces- To further improve the surface properties of DLC, films were exposed to a fluorine plasma which increased the contact angle to 99° and lowered the pull-off force by approximately 20% over that obtained with as-deposited DLC. The significance of these results is discussed with respect to stiction reduction in micromachines.

Co3O4 Nanoparticles as a Noninvasive Electrochemical Sensor for Glucose Detection in Saliva

NANO ◽  
2020 ◽  
pp. 2150009
Author(s):  
Mei Wang ◽  
Fang Liu ◽  
Zhifeng Zhang ◽  
Erchao Meng ◽  
Feilong Gong ◽  
...  
Keyword(s):  
Glucose Sensor ◽  
Saliva Sample ◽  
High Sensitivity ◽  
Single Step ◽  
Uniform Structure ◽  
Glucose Detection ◽  
Co3o4 Nanoparticles ◽  
Glucose Levels ◽  
Maximal Sensitivity ◽  
Sensitivity And Selectivity

A new noninvasive glucose sensor is developed based on Co3O4 particles (Co3O4 NPs), which are synthesized by a single-step hydrothermal method with uniform structure and size. The electrochemical measurements reveal that the device exhibits outstanding performance for glucose detection, achieving a maximal sensitivity of 2495.79[Formula: see text][Formula: see text]A mM[Formula: see text] cm[Formula: see text] with a high [Formula: see text] of 0.99575, a ultra-low detection limit of 9.3[Formula: see text]nM with a signal-to-noise of 3 and linear range up to 3[Formula: see text]mM. The noninvasive glucose sensor can respond swiftly and selectively due to the high electrocatalytic activity of Co3O4 NPs. The sensor also shows its high sensitivity and selectivity in detecting glucose levels in human blood serum and saliva sample, confirming the application potential of Co3O4 NPs in noninvasive detection of glucose.

scholarly journals Nanostructured copper selenide as an ultrasensitive and selective non-enzymatic glucose sensor

2021 ◽  
Author(s):  
Siddesh Umapathi ◽  
Harish Singh ◽  
Jahangir Masud ◽  
Manashi Nath
Keyword(s):  
Detection Limit ◽  
High Efficiency ◽  
Glucose Sensor ◽  
High Sensitivity ◽  
Copper Selenide ◽  
Glucose Detection ◽  
Applied Potential ◽  
Detection Range ◽  
Low Detection Limit ◽  
Linear Detection

CuSe nanostructures exhibit high-efficiency for glucose detection with high sensitivity (19.419 mA mM−1 cm−2) and selectivity at low applied potential (0.15 V vs. Ag|AgCl), low detection limit (0.196 μM) and linear detection range (100 nM to 40 μM).

scholarly journals Simply synthesized nitrogen-doped graphene quantum dot (NGQD)-modified electrode for the ultrasensitive photoelectrochemical detection of dopamine

Nanophotonics ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 3831-3839 ◽  
Author(s):  
Jin Wang ◽  
Cheng Lu ◽  
Tingting Chen ◽  
Lanping Hu ◽  
Yukou Du ◽  
...  
Keyword(s):  
Quantum Effect ◽  
Graphene Quantum Dots ◽  
High Sensitivity ◽  
Photoelectrochemical Activity ◽  
Detection Range ◽  
Nitrogen Doped ◽  
Nitrogen Doped Graphene ◽  
Long Term Experiment ◽  
Doped Graphene ◽  
Quantum Semiconductor

AbstractRecently, nitrogen-doped graphene quantum dots (NGQDs), as a new type of quantum semiconductor and photoelectrochemical material, are promising candidates in photoelectric sensing, water splitting, and biological imaging and have various potential application prospects. In this work, NGQDs were prepared by a simple calcination method, and then a photoelectrochemical sensing platform based on the NGQDs electrode with superior photoelectrochemical activity was designed and fabricated for the detection of dopamine (DA). Benefitting from the quantum effect and size effect, NGQDs displayed an enhanced photocurrent effective within ultra-low detection limit (0.03 μm), wide detection range (0.03–450 and 450–9680 μm), and high sensitivity in detecting DA with the assistance of ultraviolet light irradiation. The NGQDs electrode also showed continuous and stable photocurrent densities after long-term experiment, indicating the excellent durability of NGQDs for DA detection.

Deposition of Diamond-Like Carbon Films on Polyoxymethylene Substrates by Magnetic Filtered Cathodic Vacuum Arc Deposition

2008 ◽  
Vol 47-50 ◽  
pp. 1415-1418
Author(s):  
Lan Xin Xu ◽  
Peng Li ◽  
Jin Wang ◽  
Yong Xiang Leng ◽  
Hong Sun ◽  
...  
Keyword(s):  
Photoelectron Spectroscopy ◽  
Carbon Films ◽  
Vacuum Arc ◽  
Diamond Like Carbon ◽  
Dlc Film ◽  
Vacuum Arc Deposition ◽  
Filtered Cathodic Vacuum Arc ◽  
Arc Deposition ◽  
Ball On Disc

In order to improve the abrasion property of polyoxymethylene (POM)，diamond like carbon (DLC) film was deposited on POM substrate by the method of magnetic filtered cathodic vacuum arc deposition (MFCVAD). X-ray photoelectron spectroscopy (XPS) showed that the sp3 fraction decreased with the negative bias voltages increased. According to the result of the nano-indenter, the hardness of POM plates coated with DLC films was significantly harder than POM substrate. The results of ball-on-disc tribological testing demonstrated that the hardest DLC film had the lowest friction coefficient (0.11). The evaluation of in vitro platelet adhesion test indicates that the numbers of adhered and activated platelet on the DLC film deposited under the condition of 0V and 9min were remarkably decreased compared with that of the untreated POM.

Sign in / Sign up

Export Citation Format

Share Document