scholarly journals Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

PLoS Medicine ◽  
2020 ◽  
Vol 17 (3) ◽  
pp. e1003062 ◽  
Author(s):  
Tom G. Richardson ◽  
Eleanor Sanderson ◽  
Tom M. Palmer ◽  
Mika Ala-Korpela ◽  
Brian A. Ference ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Mendelian Randomisation ◽  
Lipoprotein Lipids ◽  
The Relationship

Mortality and associated risk factors in diabetics

1985 ◽  
Vol 110 (4_Suppl) ◽  
pp. S21-S26 ◽  
Author(s):  
R. J. Jarrett ◽  
M. J. Shipley
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Mortality Risk ◽  
Mortality Rates ◽  
Potential Risk Factors ◽  
Diabetic Population ◽  
Associated Risk Factors ◽  
The Relationship

Summary. In 168 male diabetics aged 40-64 years participating in the Whitehall Study, ten-year age adjusted mortality rates were significantly higher than in non-diabetics for all causes, coronary heart disease, all cardiovascular disease and, in addition, causes other than cardiovascular. Mortality rates were not significantly related to known duration of the diabetes. The predictive effects of several major mortality risk factors were similar in diabetics and non-diabetics. Excess mortality rates in the diabetics could not be attributed to differences in levels of blood pressure or any other of the major risk factors measured. Key words: diabetics; mortality rates; risk factors; coronary heart disease. There are many studies documenting higher mortality rates - particularly from cardiovascular disease -in diabetics compared with age and sex matched diabetics from the same population (see Jarrett et al. (1982) for review). However, there is sparse information relating potential risk factors to subsequent mortality within a diabetic population, information which might help to explain the increased mortality risk and also suggest preventive therapeutic approaches. In the Whitehall Study, a number of established diabetics participated in the screening programme and data on mortality rates up to ten years after screening are available. We present here a comparison of diabetics and non-diabetics in terms of relative mortality rates and the influence of conventional risk factors as well as an analysis of the relationship between duration of diabetes and mortality risk.

scholarly journals Up-Beat UK: A programme of research into the relationship between coronary heart disease and depression in primary care patients

2011 ◽  
Vol 12 (1) ◽  
Author(s):  
André Tylee ◽  
Mark Ashworth ◽  
Elizabeth Barley ◽  
June Brown ◽  
John Chambers ◽  
...  
Keyword(s):  
Primary Care ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Primary Care Patients ◽  
The Relationship

scholarly journals Insulin Resistance and the Relationship of a Dyslipidemia to Coronary Heart Disease

2011 ◽  
Vol 31 (5) ◽  
pp. 1208-1214 ◽  
Author(s):  
Sander J. Robins ◽  
Asya Lyass ◽  
Justin P. Zachariah ◽  
Joseph M. Massaro ◽  
Ramachandran S. Vasan
Keyword(s):  
Insulin Resistance ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Relationship Of ◽  
The Relationship

Antioxidant potential of diet: Association between dietary antioxidant index and odds of coronary heart disease: A case-control study

2021 ◽  
pp. 1-13
Author(s):  
Farhad Vahid ◽  
Zahra Nasiri ◽  
Amir Abbasnezhad ◽  
Ezatollah Fazeli Moghadam
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Antioxidant Capacity ◽  
Case Control Study ◽  
Case Control ◽  
P Value ◽  
Dietary Antioxidants ◽  
Dietary Antioxidant ◽  
The Relationship ◽  
Control Study

BACKGROUND: Oxidative stress and chronic inflammation are among the leading causes of coronary heart disease (CHD). Studies investigated the relationship between dietary antioxidants and the risk/odds of CHD, and contradictory results have been reported. Dietary antioxidant index (DAI) is a novel and reliable nutritional tool that examines the diet’s overall antioxidant capacity. Its validity was examined using serum total antioxidant capacity and malondialdehyde. OBJECTIVE: This study aimed to investigate the relationship between DAI score and odds of CHD. METHODS: In this incidence case-control study, 320 individuals with a definitive diagnosis of CHD and 320 participants without CHD or related risk factors attending the same hospitals/polyclinics were selected as the case and control groups. We estimated the DAI by summing up six standardized intakes of major dietary antioxidants, including manganese, vitamin E, A, C, selenium, and zinc. RESULTS: Modeling DAI categorized according to the median (–0.38), in multi-adjusted model showed a significant protective association with the odd of CHD (OR = 0.72; 95%CI:0.51–0.99, p-value = 0.05). Also, modeling DAI as a continuous variable in multi-adjusted models (OR = 0.94;95%CI:0.90–0.95; p-value = 0.01) showed significant results. CONCLUSION: Using the DAI to investigate the relationship between dietary antioxidants and CHD can show more realistic results than a single study of antioxidants.

scholarly journals THE RELATIONSHIP OF PSYCHOLOGICAL DISTRESS AND FRAMINGHAM SCORE IN POPULATION AT RISK OF CORONARY HEART DISEASE IN MALANG, INDONESIA

2020 ◽  
Vol 53 (2) ◽  
Author(s):  
Mareta Deka Paraswati ◽  
Niken Asih Laras Ati ◽  
Titin Andri Wihastuti ◽  
Yulian Wiji Utami ◽  
Kumboyono Kumboyono
Keyword(s):  
At Risk ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Psychological Distress ◽  
Framingham Score ◽  
Population At Risk ◽  
Relationship Of ◽  
The Relationship

Abstract P251: Relationship Between Reactive Hyperemia Index in Patients with Coronary Artery Disease With the Cardiac Function and Prognosis

Hypertension ◽  
2017 ◽  
Vol 70 (suppl_1) ◽  
Author(s):  
Liu Tianhu ◽  
Yu Chaoping ◽  
Xu Fengcheng
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Correlation Analysis ◽  
Cardiac Function ◽  
Cardiovascular Events ◽  
Reactive Hyperemia ◽  
Reactive Hyperemia Index ◽  
Health Group ◽  
The Relationship

Objective: To investigate the relationship between reactive hyperemia index(RHI) in patients with coronary heart disease (CHD) with the cardiac function and prognosis, intervention so as to provide guidance for coronary heart disease severity and prognosis assessment. Methods: 500 cases of volunteers had coronary artery angiography by Judkins method in our hospital. coronary angiography showing one or more quarantine branch of coronary artery stenosis lower than 50% or more were taken as the standard for coronary heart disease diagnosis, and the volunteers were divided into CHD group (n=81) and health group (n=419). RHI and left ventricular ejection fraction (LVEF) of two groups were detected. The CHD group were followed up for 1 year and survival prognosis and cardiovascular events prognosis of the patients were statistically analyzed and the relationship between RHI and LVEF, cardiovascular events rate and mortality were analyzed. Results: Compared with health group, RHI and LVEF of CHD group were lower ( P <0. 05). RHI of patient in CHD group with LVEF ≥ 50% were higher than that of patient with LVEF < 50% ( P <0. 05). Pearson correlation analysis results showed that RHI and LVEF of CHD patients were positively correlated (r=0.827, P <0. 05). Coronary heart disease group were followed up for 1 year and the cardiovascular events rates and mortality rates were 28.40% and 9.88% respectively, and RHI and LVEF of patient with cardiovascular events were lower than that of patients without coronary heart disease, and RHI and LVEF of death patients were also lower than that of survived patients ( P <0. 05). Spearman unconditionally correlation analysis results showed that the RHI and cardiovascular events and mortality in patients with CHD are negatively correlated (r=-0.794, -0.762, P <0. 05). Conclusion: RHI in CHD patients is lower and closely related to the cardiac function and prognosis, this may be related to RHI reflecting endothelial function and endothelial function damage of CHD associating with disease development, therefore, RHI may be reference indicators of disease severity and prognosis assessment of CHD.

Sign in / Sign up

Export Citation Format

Share Document