scholarly journals Family History of Education Predicts Eating Disorders across Multiple Generations among 2 Million Swedish Males and Females

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e106475 ◽  
Author(s):  
Anna Goodman ◽  
Amy Heshmati ◽  
Ilona Koupil
2011 ◽  
Vol 165 (1) ◽  
pp. 97-105 ◽  
Author(s):  
P Goudet ◽  
C Bonithon-Kopp ◽  
A Murat ◽  
P Ruszniewski ◽  
P Niccoli ◽  
...  

ContextMultiple endocrine neoplasia type 1 (MEN1) disease is an autosomal dominant syndrome that is believed to equally affect men and women. This assumption has never been confirmed.ObjectiveThe aims of this study were to evaluate the impact of gender on the prevalence of MEN1 lesions, on their lifetime probability of occurrence, and on the diagnosis of MEN1.DesignData regarding a study of 734 cases of MEN1 from the multicenter ‘Groupe d'étude des Tumeurs Endocrines’ were analyzed.ResultsThere were 57.8% females. The prevalence and probability of pancreatic tumors were higher in males than in females (P=0.06, P=0.0004). This difference was due to gastrinomas. The prevalence and probability of developing pituitary tumors were significantly greater in females (P<0.001, P<0.0001). Thymic tumors were exclusively found in men. There were no significant gender differences in the prevalence and the probability of developing hyperparathyroidism, or adrenal and bronchial tumors, or in the proportion of positive genetic tests. A family history of MEN1 was more frequently found in men than in women at the time of diagnosis (P=0.02). In the case of pituitary tumor, the proportion of patients diagnosed with MEN1 at the time of the first lesion was lower in women (44.2%) than in men (67.3%).ConclusionThe phenotype expression of the MEN1 disease gene was different in males and females. In female patients, the possibility of MEN1 is not sufficiently taken into account. Any patient presenting a lesion that belongs to the MEN1 spectrum, such as a pituitary tumor, should be closely questioned about their family history and should be tested for hypercalcemia.


Author(s):  
Enny Dwi Oktaviyani ◽  
Licantik Licantik ◽  
Loure Florentina

Staffing information system (Simpeg) as an information provider of election Officers Work Medal Awardees Satya Lencana In RRI Palangkaraya aims to be a place of useful information provider for submission of award Satya lencana karya satya so that it could be effective, efficient, and accurate by simplifying the existing system. By having this website is expected to handle the process of logging employees so that it can help in the process of registration of a Nobel Prize Medal work of satya. Methodology in the making of this website using the method waterfall, waterfall method which consists of several parts or stages – stages, namely analysis, design, coding and testing. This methodology was chosen because every step of the development of this website is structured, and clearly documented. The programming language used is PHP and MySQL as a database. At this stage of testing this website using black box testing. Black-Box Testing to focus on the functional specifications of the program. After doing the testing, can be seen the result of this site that this website can perform its function, namely to manage data, time data family history, history of education, employment, lencan setya, data filing SKP, and PKP


Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
William Herzog ◽  
Thomas Aversano

For coronary artery disease (CAD), female gender is ’protective’, so that women typically present with clinically apparent CAD a decade later than men. We examined the extent to which traditional cardiovascular risk factor influence the age at presentation with STEMI in men and women. The Cardiovascular Patient Outcomes Research Team (C-PORT) primary PCI registry includes 7197 patients (5070 males and 2109 females) who presented with STEMI at 33 participating hospitals. The table below depicts the average age at presentation with STEMI in males and females with and without diabetes, hypercholesterolemia, hypertension, a family history of coronary artery disease and smoking history (current or former). The effect of smoking, family history and hypertension on age at presentation remained significant in multivariate analysis in both men and women. In both males and females, a family history of CAD and a positive smoking history are associated with presentation with STEMI at a younger age. Both have a greater effect in females. This is particularly true of smoking with lowers the age of presentation by 9 years in women, compared with 3.8 years in men. Male and female patients with a history of hypertension are older at presentation with STEMI, perhaps because the anti-ischemic effects of anti-hypertensive medications. We conclude that while the effect of most traditional risk factors for CAD on age at presentation with STEMI are similar in men and women, smoking lowers the age at presentation to a much greater degree in women. In women who do not smoke, STEMI is delayed for a decade or more compared to men; for women who do, the protective effect of female gender is nearly obliterated.


Author(s):  
Moslem TAHERI SOODEJANI ◽  
Seyyed Mohammad TABATABAEI ◽  
Hamid Reza SHORAKA ◽  
Hosein FALLAHZADEH ◽  
Azimeh GHADERI

Background: Congenital hypothyroidism is one of the most common endocrine disrupters and metabolism, and is one of the most important preventable causes of physical and mental disabilities. Methods: This was a case-control study, in which 54468 infants were screened from 2006 to 2014 in Shahre-Kord, western Iran. To describe the data, central and dispersion indices such as mean and standard deviation was used. For modeling, logistic regression was used. All the tests were performed at the significant level of 5%. Results: Overall, 111 cases were diagnosed with hypothyroidism, which made the prevalence value equal to 2 cases per 1000 births. The prevalence in females and males was 1.9 and 2.2 per 1,000 birth, respectively. The odds ratio for this disorder was 4.47(2.42-9.28) for the neonates with a family history of hypothyroidism and 1.72(1.05-2.82) for those born through cesarean. Conclusion: The incidence of this disorder is similar in males and females, and the incidence of this disease in people with a family history is far more than others.


2021 ◽  
pp. 1-8
Author(s):  
Ruyue Zhang ◽  
Ralf Kuja-Halkola ◽  
Andreas Birgegård ◽  
Henrik Larsson ◽  
Paul Lichtenstein ◽  
...  

Abstract Background Familial co-aggregation studies of eating disorders (EDs) and schizophrenia reveal shared genetic and environment factors, yet their etiological and clinical relationship remains unclear. We evaluate the influence of schizophrenia family history on clinical outcomes of EDs. Methods We conducted a cohort evaluation of the association between family history of schizophrenia and ED clinical features, psychiatric comorbidities, and somatic and mental health burden in individuals born in Sweden 1977–2003 with anorexia nervosa (AN) or other EDs (OED: bulimia nervosa, binge-eating disorder, and ED not otherwise specified). Results Of 12 424 individuals with AN and 20 716 individuals with OED, 599 (4.8%) and 1118 (5.4%), respectively, had a family history of schizophrenia (in up to third-degree relatives). Among individuals with AN, schizophrenia in first-degree relatives was significantly associated with increased comorbid attention-deficit/hyperactivity disorder (ADHD) [HR(95% CI) 2.26 (1.27–3.99)], substance abuse disorder (SUD) [HR (95% CI) 1.93 (1.25–2.98)], and anxiety disorders [HR (95% CI) 1.47 (1.08–2.01)], but higher lowest illness-associated body mass index (BMI) [1.14 kg/m2, 95% CI (0.19–2.10)]. Schizophrenia in any relative (up to third-degree) in AN was significantly associated with higher somatic and mental health burden, but lower ED psychopathology scores [−0.29, 95% CI (−0.54 to −0.04)]. Schizophrenia in first-degree relatives in individuals with OED was significantly associated with increased comorbid ADHD, obsessive-compulsive disorder, SUD, anxiety disorders, somatic and mental health burden, and suicide attempts. Conclusions We observed different patterns of ED-related outcomes, psychiatric comorbidity, and illness burden in individuals with EDs with and without family histories of schizophrenia and provide new insights into the diverse manifestations of EDs.


Author(s):  
Humam Ali Hade ◽  
Rasha Hasan Jasim ◽  
Sattar Jasim Hatrosh

During the period from the beginning of February 2016 to the end of October 2017 in the Center of Oncology of Hematology of El-Hussein Medical city in Karbala, 30 samples were collected for patients with acute lymphocytic leukemia ranging between 1-13 years old (6,80 ± 3, 79) who didn’t have a family history of any cancer infection before receiving chemotherapy. The study was divided into two sections based on sex. The study included 19 males aged (1 - 12 years) and 11 females aged (1- 13 years old). The results showed significant differences in the levels of trace elements (Fe), (Cu), (Zn) and (Ni) in the serum. There was significant difference (p = 0.00) between the healthy and the patients who didn’t gain medicine. Also, significant differences were in levels of fe) and Cu (cu) in serum samples in the samples of males and females with their peers in the control group. There were also significant differences when comparing the sexes in each of the two study groups. The results also showed significant differences in zn Blood samples for male and female patients with acute lymphocytic leukemia and healthy individuals, while significant differences of Ni (ni) between males and females of the infected group and healthy males.


2005 ◽  
Vol 4 (4) ◽  
pp. 286-289 ◽  
Author(s):  
Saafan A. Al-Safi

Background: Smoking is a risk factor for cardiovascular, coronary artery and thromboembolic disorders. There is overwhelming evidence supporting the association of cigarette smoking and the development of cardiovascular and thromboembolic events particularly in high risk populations. Aim: The aim of this investigation was to explore the correlation of smoking habit with blood pressure and heart rate values through a randomized cross-sectional epidemiological study in Jordan. Settings and design: This study was performed during the period of February–June 2004. The sample of this investigation included healthy adult males and females from various regions of Jordan. Most of the selected sample included Jordanian university students. Patients with hypertension or cardiovascular disorders were excluded. Methods: Selected individuals of the sample were interviewed by well-trained senior pharmacy students. They were asked initially if they have hypertension or other cardiovascular disorders and if the answer was negative, further questions were asked followed by measurement of the blood pressure and heart rate. Demographic data such as age, sex, nationality, place of residence, occupation and level of education were also recorded. Smokers (for ≥ 6 months) were asked to report how many cigarettes per day they smoke. For each individual of the sample, the systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate were measured three times with 10–15 min intervals in the sitting position and at the resting state. The arterial blood pressure (ABP) was calculated from the measured SBP and DBP. The mean values were distributed according to sex and smoking habit. Statistical analysis: The student unpaired t-test was used for statistical analysis. Results were considered statistically significant when the p value was less than 0.05. Results and conclusion: A total of 14,310 adult males (7400) and females (6910) were selected in various regions of Jordan. The frequencies of smokers and non-smokers in the sample were 3832 (26.8%) and 10478 (73.2%), respectively. Smoker males and females had significantly higher SBP, DBP, ABP values than non-smokers. However, smoking had statistically non-significant effects on heart rate in females while heart rate values were significantly higher in male smokers than in non-smokers. Smoker or non-smoker adults with a positive family history of hypertension had significantly higher blood pressure and heart rate values than those with a negative family history of hypertension. In conclusion, smokers have higher blood pressure than non-smokers.


Author(s):  
Mustefa Jibril

Chewing Khat is one of the leading causes of mental disorders in Ethiopia. An alarming increase in Khat chewing among adults since the early 1990s was reported. Studies have shown that starting chewing Khat early in life is associated with an increased risk of adverse health effects. The objective of the study: This study was conducted to measure the increase in Khat chewing among students at Dire Dawa University students in Dire Dawa City, identify the natural causes of the problem, and demonstrate students' knowledge of the effects of Khat chewing. Material and Methods: The study was separate. Dated February 2021. Students during study time (n = 302) were included. The information was collected through personal interviews and completed a list of questions prepared after reviewing. RESULTS: Male (88.2%) of responding students chewed Khat with a significant difference (P <0.001) between males and females in terms of chewing. The year of student study, academic achievement, and family history of chewing Khat had a significant impact (P <0.05) on chewer students. Of the Khat chewer students who read 35.6% reported chewing both morning and afternoon. 66.7% of students who chewed reported that they had intentions to stop chewing and 82.4% considered chewing to be dangerous. CONCLUSION: Khat chewing gum among students is considered a problem and efforts are needed to help students stop chewing and this is considered a way to prevent Khat chewing among students.


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