Temporal Relationship between Vitamin D Status and Parathyroid Hormone in the United States

ABSTRACT Background Vitamin D is important for bone health; in 2014 it was the fifth most commonly ordered laboratory test among Medicare Part B payments. Objectives The aim of this study was to describe vitamin D status in the US population in 2011–2014 and trends from 2003 to 2014. Methods We used serum 25-hydroxyvitamin D data from NHANES 2011–2014 (n = 16,180), and estimated the prevalence at risk of deficiency (<30 nmol/L) or prevalence at risk of inadequacy (30–49 nmol/L) by age, sex, race and Hispanic origin, and dietary intake of vitamin D. We also present trends between 2003 and 2014. Results In 2011–2014, the percentage aged ≥1 y at risk of vitamin D deficiency or inadequacy was 5.0% (95% CI: 4.1%, 6.2%) and 18.3% (95% CI: 16.2%, 20.6%). The prevalence of at risk of deficiency was lowest among children aged 1–5 y (0.5%; 95% CI: 0.3%, 1.1%), peaked among adults aged 20–39 y (7.6%; 95% CI: 6.0%, 9.6%), and fell to 2.9% (95% CI: 2.0%, 4.0%) among adults aged ≥60 y; the prevalence of at risk of inadequacy was similar. The prevalence of at risk of deficiency was higher among non-Hispanic black (17.5%; 95% CI: 15.2%, 20.0%) than among non-Hispanic Asian (7.6%; 95% CI: 5.9%, 9.9%), non-Hispanic white (2.1%; 95% CI: 1.5%, 2.7%), and Hispanic (5.9%; 95% CI: 4.4%, 7.8%) persons; the prevalence of at risk of inadequacy was similar. Persons with higher vitamin D dietary intake or who used supplements had lower prevalences of at risk of deficiency or inadequacy. From 2003 to 2014 there was no change in the risk of vitamin D deficiency; the risk of inadequacy declined from 21.0% (95% CI: 17.9%, 24.5%) to 17.7% (95% CI: 16.0%, 19.7%). Conclusion The prevalence of at risk of vitamin D deficiency in the United States remained stable from 2003 to 2014; at risk of inadequacy declined. Differences in vitamin D status by race and Hispanic origin warrant additional investigation.

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Living in Low-Latitude Regions in the United States Does Not Prevent Poor Vitamin D Status

Nutrition Reviews ◽

10.1111/j.1753-4887.2005.tb00138.x ◽

2005 ◽

Vol 63 (6) ◽

pp. 203-209 ◽

Cited By ~ 21

Author(s):

Sohyun Park ◽

Mary Ann Johnson

Keyword(s):

United States ◽

Vitamin D ◽

The United States ◽

Vitamin D Status ◽

Low Latitude

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Vitamin D Status and Demographic and Lifestyle Determinants among Adults in the United States (NHANES 2001-2006)

Advance Journal of Food Science and Technology ◽

10.19026/ajfst.6.104 ◽

2014 ◽

Vol 6 (6) ◽

pp. 743-750

Author(s):

Yan Cao ◽

Katie L. Callahan ◽

Sreenivas P. Veeranki ◽

Yang Chen ◽

Xuefeng Liu ◽

...

Keyword(s):

United States ◽

Vitamin D ◽

The United States ◽

Vitamin D Status

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Association Between Ready-to-Eat Cereal Consumption and Serum Level of 25-hydroxyvitamin D in US Children and Adults, NHANES 2013–2014

Current Developments in Nutrition ◽

10.1093/cdn/nzaa061_142 ◽

2020 ◽

Vol 4 (Supplement_2) ◽

pp. 1514-1514

Author(s):

Yong Zhu ◽

Neha Jain ◽

Vipra Vanage ◽

Norton Holschuh ◽

Jessica Smith

Keyword(s):

United States ◽

Vitamin D ◽

Serum Level ◽

Vitamin D Deficiency ◽

Family Income ◽

The United States ◽

Vitamin D Status ◽

Hydroxyvitamin D ◽

Health And Nutrition ◽

25 Hydroxyvitamin D

Abstract Objectives Previous studies have shown that consumption of ready-to-eat (RTE) cereal is associated with higher dietary intake of vitamin D; however, little is known about the association between RTE cereal consumption and vitamin D status measured by the serum biomarker, 25-hydroxyvitamin D. The study was conducted to examine association between consumption of RTE cereal and serum level of 25-hydroxyvitamin D, the clinical biomarker for vitamin D status in children and adults in the United States. Methods Children aged 1–18 years old (N = 2553) and adults aged 19 years or older (N = 4901) from the National Health and Nutrition Examination Survey 2013–2014 were included in the study. Day 1 dietary data were used to classify participants by RTE cereal consumption status. Vitamin D deficiency and inadequacy were assessed by serum levels of 25-hydroxyvitaminD using cut-off values recommended by the National Academy of Medicine. Adjusted odds ratio (aOR) and 95% confidence intervals (CI) were calculated using survey logistic regression for associations between RTEC consumption and vitamin D status in children and adults. Results Both children and adults who reported RTE cereal consumption had a significantly higher level of serum 25-hydroxyitamin D than children and adults who did not consume RTE cereal (P < 0.05). Adjusting for age, gender, race/ethnicity, family income to poverty ratio, season of data collection, and use of vitamin D containing supplements, children who consumed RTE cereal were less likely to have vitamin D inadequacy than non-eaters (aOR = 0.48, 95% CI = [0.34, 0.68]). In adults, RTEC eaters were less likely to have vitamin D deficiency than non-eaters (aOR = 0.52, 95% CI = [0.28, 0.97]). Conclusions Consumption of RTE cereal is associated with better vitamin D status in both children and adults in the United States. Funding Sources The study was funded by the Bell Institute of Health and Nutrition, General Mills, Inc.

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Prevalence of Vitamin D Deficiency in a Large Newborn Cohort from Northern United States and Effect of Intrauterine Drug Exposure

Nutrients ◽

10.3390/nu12072085 ◽

2020 ◽

Vol 12 (7) ◽

pp. 2085

Author(s):

Neelakanta Kanike ◽

Krupa Gowri Hospattankar ◽

Amit Sharma ◽

Sarah Worley ◽

Sharon Groh-Wargo

Keyword(s):

United States ◽

Vitamin D ◽

Vitamin D Deficiency ◽

Drug Exposure ◽

Illicit Drug ◽

Retrospective Chart Review ◽

The United States ◽

Vitamin D Status ◽

Term Neonates ◽

Vitamin D Levels

Vitamin D is not only a vital element in bone health but is also a prohormone. Data regarding distribution of vitamin D status among preterm and term neonates in the United States are limited. There are no data on the effect of intrauterine drug exposure on vitamin D status. Our objective was to determine the distribution of vitamin D levels among preterm and term neonates and the effect of intrauterine illicit drug exposure. We did a retrospective chart review of neonates admitted from 2009 to 2016 to our neonatal intensive care unit with serum 25-hydroxycholecalciferol (25[OH]D) levels measured during the hospital stay. Of 1517 neonates, the median 25[OH]D level was 19 ng/mL with 31% deficient and 49% insufficient, even though 75% of mothers took prenatal vitamins. In pregnant women, 38% were vitamin-D-deficient and 44% were vitamin-D-insufficient. Four hundred seventy-one neonates had intrauterine drug exposure, with a median 25[OH]D level of 22.9 ng/mL versus 17.8 ng/mL in nonexposed neonates (p = 0.001). Despite maternal prenatal vitamin intake, neonates are at risk of vitamin D deficiency. Maternal illicit drug use was not related to lower 25[OH]D levels in neonates.

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