scholarly journals Serum symmetric dimethylarginine shows a relatively consistent long-term concentration in healthy dogs with a significant effect of increased body fat percentage

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0247049
Author(s):  
Amber Hillaert ◽  
Daisy J. X. Liu ◽  
Sylvie Daminet ◽  
Bart J. G. Broeckx ◽  
Emmelie Stock ◽  
...  

Symmetric dimethylarginine (SDMA) is a promising renal marker that correlates well with the glomerular filtration rate and could allow earlier detection of impaired renal function. The main objectives of this study were to assess the long-term variability of SDMA in healthy dogs and examine the influence of an increased body fat percentage on the level of SDMA. Sixteen lean Beagles were randomly assigned to the control group or weight-change group in age- and gender-matched pairs. The energy intake of the control group (n = 8) was strictly regulated to maintain an ideal body weight for 83 weeks, while the weight-change group (n = 8) was fed to induce weight gain (week 0–47), to maintain stable excessive body weight (week 47–56) and to lose weight (week 56–83), consecutively. At 8 specified time points, the body condition score, body composition, glomerular filtration rate, serum concentration of SDMA and creatinine were analyzed. In the control group, the within-subject coefficient of variation, between-subject coefficient of variation, reference change value (type I error = 5%) and index of individuality were 0.16, 0.22, 0.43 and 0.73, respectively. The control group and weight-change group did not differ significantly in SDMA concentration. SDMA showed a significant negative association (coefficient = -0.07) with body fat percentage (p<0.01) in the weight-change group and a significant positive association (coefficient = 7.79) with serum creatinine (p<0.01) in the entire study population. In conclusion, SDMA concentration has high long-term stability in healthy adult dogs. For the evaluation of SDMA concentrations, subject-specific reference values are preferred over a population-based reference value seen their higher sensitivity. Moreover, an increased body fat percentage does seem to affect the serum SDMA concentration of otherwise healthy dogs, but its clinical relevance has to be clarified in further research.

Author(s):  
Boštjan Jakše ◽  
Barbara Jakše ◽  
Stanislav Pinter ◽  
Jernej Pajek ◽  
Nataša Fidler Mis

Failure of various weight-loss programs and long-term maintenance of favorable body composition in all kinds of people is high, since the majority go back to old dietary patterns. Many studies have documented the efficacy of a plant-based diet (PBD) for body mass management, but there are opinions that maintaining a PBD is difficult. We aimed to evaluate the long-term success of a whole-food plant-based (WFPB) lifestyle program. We investigated the differences in the obesity indices and lifestyle of 151 adults (39.6 &plusmn; SD 12.5 years), who were on our program for short (0.5&ndash;&lt;2 years), medium (2&ndash;&lt;5 years), or long term (5&ndash;10 years). Body-composition changes were favourable for all three groups, both genders and all participants. There were no differences in relative body-composition changes (BMI, body fat percentage and muscle mass index (MMI)) between the three groups. All participants improved their BMI (baseline mean pre-obesity BMI range (kg/m2): 26.4 &plusmn; 5.6 to normal 23.9 &plusmn; 3.8, p &lt; 0.001), decreased body mass (&ndash;7.1 &plusmn; 8.3 kg, p &lt; 0.001) and body fat percentage (&ndash;6.4 &plusmn; 5.6 % points, p &lt; 0.001). 85.6% (101 out of 118) of parents of underage children (&lt; 18 years), introduced WFPB lifestyle to their children. Those with the highest BMI at baseline lost the most of: a) BMI units, b) total body mass and c) body fat (a) (kg/m2) (&ndash;5.6 &plusmn; SD 2.9, &ndash;2.4 &plusmn; 1.8 and &ndash;0.9 &plusmn; 1.5), b) (kg) (&ndash;16.1 &plusmn; SD 8.8, &ndash;7.1 &plusmn; 5.4 and &ndash;2.5 &plusmn; 4.5) and c) (% points) (&ndash;9.5 &plusmn; SD 5.7, &ndash;6.6 &plusmn; 4.6 and &ndash;4.7 &plusmn; 5.3) for participants who had baseline BMI in obese, overweight and normal range, respectively; pbaseline vs. current &lt; 0.001 for all). WFPB lifestyle program provides long-term lifestyle changes for reversal of obesity and is effective transferred to the next generation.


2020 ◽  
pp. 155982762094920
Author(s):  
Boštjan Jakše ◽  
Barbara Jakše ◽  
Stanislav Pinter ◽  
Jernej Pajek ◽  
Nataša Fidler Mis

Failure of weight-loss programs is high. We evaluated a whole-food plant-based (WFPB) lifestyle program. We investigated the obesity indices of 151 healthy adults who were on our ongoing, community-based program for the short (0.5 to ≤2 years), medium (2 to ≤5 years), or long term (5 to 10 years). Body composition indices were measured by medically approved bioimpedance. Body composition changes were favorable for all 3 groups and both genders. There were no differences in body composition between the males for all 3 groups, while there were lower body mass (BM), body mass index (BMI), and muscle mass in females on long-term versus short-term programs. All participants experienced a decrease in BMI (−2.5 kg/m2), BM (−7.1 kg), and body fat percentage (−6.4%; P < .001 for all). The reductions for those with a baseline BMI of obese, overweight, and normal were −5.6, −2.4, and −0.9 kg/m2 for BMI, −16.1, −7.1, and −2.5 kg for total BM, and −9.5%, −6.6%, and −4.8% for body fat percentage (baseline vs current; P < .001 for all). A total of 86% of parents of underage children introduced the WFPB lifestyle to children. Our WFPB lifestyle program provides a long-term reversal of obesity.


Author(s):  
Seunghui Baek ◽  
Jong-Beom Park ◽  
Sang-Hwan Choi ◽  
Jae-Don Lee ◽  
Sang-Seok Nam

Background: The purpose of this study is to investigate the effect of Taekwondo training on body composition and to evaluate the magnitude of the effect. Methods: Databases were used to select studies related to the effectiveness of Taekwondo training, and the inclusion criteria were as follows. Results: Thirty-seven studies were selected. We found statistically significant differences from the control group in weight, body mass index (BMI), waist circumference (WC), waist–hip ratio (WHR), body fat mass, body fat percentage, lean mass, and muscle mass. Also, the age group was statistically significant in control variables on weight, BMI, and body fat percentage. Conclusions: Taekwondo training had a positive effect on body composition, and these results suggest that Taekwondo training is an effective exercise method to lower obesity.


Author(s):  
Farhad Towhidi ◽  
Khalid Mohammadzadeh Salamat ◽  
Ali Soroush ◽  
Ali Pourmotabbed

Background: Obesity is known as one of the most important cardiovascular risk factors. Objectives: This quasi-experimental study was conducted to investigate the effect of an eight-week aerobic exercise and garlic extract use on the blood pressure, fat percentage, and lipid profile of patients with hypertension. Methods: A total of 50 men with a mean age of 53 ± 7.6 years were recruited from among obese patients with blood pressure. They were randomly divided into five groups of aerobic exercise, garlic extract, aerobic exercise plus garlic extract, placebo, and control. The experimental groups underwent aerobic exercise (3 sessions per week, each session for 35 - 60 min with a maximum heart rate of 50 - 75) or garlic extract supplementation (daily use of 6 g) for eight weeks. Blood samples were collected before interventions and 48 h after the last exercise session. Statistical analysis was done by the dependent t-test and ANCOVA. Results: Body weight, body fat percentage, systolic and diastolic blood pressures, and serum LDL significantly reduced in the aerobic exercise, garlic extract, and aerobic exercise plus garlic extract groups compared to the control group (P ≤ 0.05). Aerobic exercise and aerobic exercise plus garlic extract groups showed a significant decrease in total cholesterol level and serum triglyceride and an increase in serum HDL compared to the control group (P ≤ 0.05). Aerobic exercise plus garlic extract group indicated a higher increase in serum HDL and a higher decrease in the body weight, body fat percentage, and serum LDL compared with the control group (P ≤ 0.05). Aerobic exercise plus garlic extract group indicated a higher serum LDL decrease compared to the aerobic exercise group (P ≤ 0.01). Conclusions: Both aerobic exercise and garlic extract seem to be able to improve obesity, lipid profile, and hypertension. However, their concurrent use has no additional effects on the blood pressure control although it mostly influences lipid profile and body composition.


2001 ◽  
Vol 14 (3) ◽  
pp. 177-183
Author(s):  
Aline Rodrigues BARBOSA ◽  
José Maria SANTARÉM ◽  
Wilson JACOB FILHO ◽  
Maria de Fátima Nunes MARUCCI

This study analyzed the effects of a 10-wk resistance training program on body composition in 11 elderly women (68.91 ± 5.43 yrs). A control group of 8 women (65.13 ± 4.09 yrs) served as inactive control. The body fat percentage (skinfold thickness and bioelectrical impedance), body-circumference measurements and sum of skinfolds were assessed before and after 10 weeks. Food intake was assessed immediately before week 0 and week 10, from 3-day diet records (energy, protein, carbohydrate and fat). After initial tests, the subjects began a training program consisting of eight exercises for the whole body. The training program only resulted in decrease in sum of skinfolds (p<=0.05). No significant changes in any variable were observed in the control group. In conclusion, the training program did not reduce body fat percentage, although it reduced sum of skinfolds.


2020 ◽  
pp. 1-9 ◽  
Author(s):  
Irene A. Garcia-Yu ◽  
Luis Garcia-Ortiz ◽  
Manuel A. Gomez-Marcos ◽  
Emiliano Rodriguez-Sanchez ◽  
Cristina Lugones-Sanchez ◽  
...  

Abstract During menopause, women undergo a series of physiological changes that include a redistribution of fat tissue. This study was designed to investigate the effect of adding 10 g of cocoa-rich chocolate to the habitual diet of postmenopausal women daily on body composition. We conducted a 6-month, two-arm randomised, controlled trial. Postmenopausal women (57·2 (sd 3·6) years, n 132) were recruited in primary care clinics. Participants in the control group (CG) did not receive any intervention. Those of the intervention group (IG) received 10 g daily of 99 % cocoa chocolate in addition to their habitual diet for 6 months. This quantity comprises 247 kJ (59 kcal) and 65·4 mg of polyphenols. The primary outcomes were the between-group differences in body composition variables, measured by impendancemetry at the end of the study. The main effect of the intervention showed a favourable reduction in the IG with respect to the CG in body fat mass (–0·63 kg (95 % CI –1·15, –0·11), P = 0·019; Cohen’s d = –0·450) and body fat percentage (–0·79 % (95 % CI –1·31, –0·26), P = 0·004; Cohen’s d = –0·539). A non-significant decrease was also observed in BMI (–0·20 kg/m2 (95 % CI –0·44, 0·03), P = 0·092; Cohen’s d = –0·345). Both the body fat mass and the body fat percentage showed a decrease in the IG for the three body segments analysed (trunk, arms and legs). Daily addition of 10 g of cocoa-rich chocolate to the habitual diet of postmenopausal women reduces their body fat mass and body fat percentage without modifying their weight.


2018 ◽  
Vol 7 (1) ◽  
pp. 1-8
Author(s):  
Marisi Elizabeth R. Silitonga ◽  
K. Heri Nugroho HS ◽  
Kusmiyati Tjahjono ◽  
Nyoman Suci Widyastiti ◽  
Diana Nur Afifah

Background: Metabolic syndrome is related to glucose metabolism disturbance (hyperglycemia), lipid (dyslipidemia), high blood pressure, and central obesity. Metabolic syndrome implicates to heart attack, diabetes mellitus, hypertension, and death. Aloe vera, well known rich of polyphenol and vitamin, has a pharmacological effect to improve insulin resistance, chronic inflammation, and oxidative stress.Objective: To prove the effect of Aloe vera-based drink toward total antioxidant concentration improvement and body fat percentage reduction in metabolic syndrome subjects.Methods: Thus study was pre-post randomized true experimental study with control group design. The subjects were divided by 2 groups, treatment group (n=19) and control group (n=19). Treatment group was given 165 g/d Aloe vera-based drink for 30 days. Both of groups were given nutrition education about metabolic syndrome management. Total antioxidant concentration and body fat percentage were assessed pre-post-test by ABTS and BIA respectively, while food intake and activity were assessed by 24-h recall and GPAQ respectively. Independent t-test and Mann Whitney test were used to compare before and after treatment between control and treatment group.Results: Total antioxidant concentration significantly improved (p=0.00) in treatment group from 1.2 to 2.0 mmol/L, while total antioxidant concentration decreased from 1.4 to 1.3 mmol/L (p=0.074) in this control group. Moreover, there was significant difference of total antioxidant between treatment and control groups in the end of study (p=0.00). Furthermore, body fat percentage was reduced significantly from 32.8 to 32,4 mmol/L (p=0.005) in treatment group, while the reduction of body fat percentage in control group was not significant from 33.1 to 33,4 mmol/L (p=0.100). There was no difference of body fat percentage between two groups after intervention (p=0.358).Conclusion: Aloe vera-based drink improved total antioxidant concentration in metabolic syndrome subjects.


2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Ewa Jednacz ◽  
Lidia Rutkowska-Sak

The study was aimed to evaluate cardiovascular risk parameters, body mass index (BMI) centiles for sex and age, and body fat percentage using the electric bioimpedance method in children with juvenile idiopathic arthritis (JIA). 30 children with JIA participated in the study. A control group included 20 children. Patients were well matched for the age and sex. The body mass and body fat percentage were determined using the segmental body composition analyser; the BMI centiles were determined. All patients had the following parameters determined: lipid profile, hsCRP, homocysteine, and IL-6. The intima media thickness (IMT) was measured. Patients with JIA had significantly lower body weight, BMI, and the BMI centile compared to the control group. The IL-6 levels were significantly higher in patients with JIA compared to the control group. There were no differences between two groups with regard to the lipid profile, % content of the fat tissue, homocysteine levels, hsCRP, and IMT. Further studies are necessary to search for reasons for lower BMI and BMI centile in children with JIA and to attempt to answer the question of whether lower BMI increases the cardiovascular risk in these patients, similarly as in patients with rheumatoid arthritis (RA).


2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Okan Bakiner ◽  
Emre Bozkirli ◽  
Emine Duygu Ersozlu Bozkirli ◽  
Kursat Ozsahin

Aim. We aimed to observe the effects of L-thyroxine replacement therapy on body fat content determined with various anthropometric methods and a bioelectrical impedance analysis method in patients with hypothyroidism.Methods. Forty-two women with naive autoimmune hypothyroidism were included. Also, 40 healthy participants were enrolled as a control group. Weight, body mass index, waist circumference, and subscapulary, suprailiac, femur, biceps, and triceps skin fold thicknesses were measured. Body fat percentages were calculated and body fat measurements were performed. Euthyroidism was maintained with L-thyroxine. At the 6th and 18th month, of therapy, measurements were reperformed.Results. Mean TSH levels were  mIU/L in hypothyroid group and  mIU/L in control subjects at admission. In hypothyroid patients, calculated body fat percentages were greater than those of the control subjects during follow-up. Body fat percentage of each hypothyroid case decreased at 6- and 18-month controls, but the decrements were statistically insignificant. Although skin fold thicknesses measured from all sites were observed to decline, only those obtained from femur and biceps showed a significant decrease ( and , resp.).Discussion. Correction of hypothyroidism did not cause any improvement in body weight and body fat percentage. The decrease in skin fold thicknesses might probably result from the reduction in subcutaneous mucopolysaccharide deposits.


2021 ◽  
Vol 13 (16) ◽  
pp. 8746
Author(s):  
Tomás Herrera-Valenzuela ◽  
Johan Carter ◽  
Elvis Leiva ◽  
Pablo Valdés-Badilla ◽  
Alex Ojeda-Aravena ◽  
...  

The present study investigated the effect of an additional short-duration HIIT program using boxing-specific techniques on activity during a simulated competition. Additionally, we investigated the impact on physical fitness, specifically aerobic performance and lower-body muscle power. Sixteen boxers were randomized into a control (n = 8) or experimental groups (n = 8). The experimental protocol consisted of 3 blocks of 5 repetitions of 30s all-out effort, with 6s recovery between repetitions and 1 min rest interval between blocks, conducted 3 days per week for 4 weeks. A two-way (group, two levels; moment, two levels) analysis of variance with repeated measurements in the second factor was used. For the experimental group, there was a change in body mass (ES = −0.13 (trivial)), body fat percentage (ES = −0.12 (trivial)), VO2max (ES = +0.42 (small)), CMJ (ES = +0.12 (trivial)), CMJ-left (ES = −0.11 (trivial)), CMJ-right (ES = +0.22 (trivial)), actions (ES = +0.68 (moderate)), time (ES = −0.29 (small)) and punches (ES = +0.56 (moderate)). For the control group, there was a change in body mass (ES = +0.04 (trivial)), body fat percentage (ES = −0.12 (trivial)), VO2max (ES = +0.11 (trivial)), CMJ (ES = −0.27 (small)), CMJ-left (ES = −0.39 (small)), CMJ-right (ES = +0.08 (trivial)), actions (ES = +0.08 (trivial)), time (ES = −0.65 (moderate)) and punches (ES = −0.57 (moderate)). The punches variable was significant concerning group-by-time interaction (F1,14 = 11.630; p = 0.004; n2 = 0.454). The present study indicated that the addition of a boxing-specific HIIT program is effective to increase the number of punches during a simulated match.


Sign in / Sign up

Export Citation Format

Share Document