scholarly journals Risk factors associated with the development of delirium in general ICU patients. A prospective observational study

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0255522
Author(s):  
Beatriz Lobo-Valbuena ◽  
Federico Gordo ◽  
Ana Abella ◽  
Sofía Garcia-Manzanedo ◽  
Maria-Mercedes Garcia-Arias ◽  
...  
Keyword(s):  
Risk Factors ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Hospital Length ◽  
Risk Scores ◽  
Clinical Frailty Scale ◽  
Saps 3 ◽  
Factors Associated ◽  
Organ Failures

Objective We aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk. Material and methods Observational study, including prospectively collected patients treated in a single general ICU. These were classified into two groups, according to whether they developed delirium or not (screening performed using CAM-ICU tool). Demographics and clinical data were analyzed. Multivariate logistic regression analyses were performed to quantify existing associations. Results 1462 patients were included. 93 developed delirium (incidence: 6.3%). These were older, scored higher on the Clinical Frailty Scale, on the risk scores on admission (SAPS-3 and SOFA), and had a greater number of organ failures (OF). We observed more incidence of delirium in patients who (a) presented more than two OF (20.4%; OR 4.9; CI95%: 2.9–8.2), and (b) were more than 74 years old albeit having <2 OF (8.6%; OR 2.1; CI95%: 1.3–3.5). Patients who developed delirium had longer ICU and hospital length-of-stays and a higher rate of readmission. Conclusions The highest risk observed for developing delirium clustered in patients who presented more than 2 OF and patients over 74 years old. The detection of patients at high risk for developing delirium could imply a change in management and improved quality of care.

scholarly journals Comparison of the Contamination Rate and Risk Factor Profile of Blood Culture Done in Emergency Department and MHDU/MICUs

2021 ◽  
pp. 1-8
Author(s):  
Dr. Pankaj Kumar Singh
Keyword(s):  
Risk Factors ◽  
Emergency Department ◽  
Risk Factor ◽  
Blood Culture ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Contamination Rate ◽  
Medical Illness ◽  
Inclusion Criteria ◽  
Factors Associated

Aims and objectives: To determine the risk factors of blood culture contamination done in ED and those done in the MHDU/MICU among patients admitted with medical illness. Material and Methods: This is a two months’ prospective observational study comparing blood culture contamination rate and risk factors associated with contamination between ED and MICU/MHDU. A total of 998 patients were included in the study who underwent blood culture in ED and MICU/MHDU. 570 in ED and 428 in MICU/MHDU were included after meeting exclusion and inclusion criteria. Results: Blood culture growths were higher in ED (19%). Most common growth was CoNS (4%). The overall contamination rate in this study was (4.8%) The contamination rate was lower in ED (4.4%) when compared to MICU/MHDU (5.4%).

Risk Factors Associated With Early Reintubation in Trauma Patients: A Prospective Observational Study

2011 ◽  
Vol 71 (1) ◽  
pp. 37-42 ◽  
Author(s):  
Carlos V. R. Brown ◽  
Jacob B. Daigle ◽  
Kelli H. Foulkrod ◽  
Brandee Brouillette ◽  
Adam Clark ◽  
...  
Keyword(s):  
Risk Factors ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Trauma Patients ◽  
Factors Associated

A Prospective Observational Study of the Determinants of Current Cataract Surgical Selection

2008 ◽  
pp. 1111-1124
Author(s):  
B. Dhillon ◽  
P. Aspinall ◽  
T. Aslam ◽  
P. Halpin ◽  
A. Vani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Observational Study ◽  
Visual Function ◽  
False Positive ◽  
Prospective Observational Study ◽  
False Negative ◽  
Research Proposal ◽  
Policy Decisions

The principal aim of this research proposal was to develop quality of life and relevant visual function criteria to provide a rational decisional framework to be used as a basis for individual and policy decisions on cataract referral and surgery. There are two key objectives within this overall aim. The first is to identify reliable and effective quality of life and visual function criteria to determine the threshold for surgery for each individual patient in which false positive and false negative errors are minimized. The second is to provide a decisional framework in which risk factors may be incorporated to assess the likely outcome benefits from surgery.

scholarly journals A PROSPECTIVE OBSERVATIONAL STUDY ON THE EVALUATION OF RISK FACTORS IN PATIENTS DIAGNOSED WITH CORONARY ARTERY DISEASE IN TERTIARY CARE HOSPITAL.

2020 ◽  
pp. 283-286
Author(s):  
CHINMAYI PINNA ◽  
Dharavath Vinay Naik Dharavath Vinay Naik ◽  
Naresh Podugu Naresh Podugu ◽  
Shaik.Mohammed Shaabaaz Shaik.Mohammed Shaabaaz ◽  
Okeke Chukwugoziem Bright Okeke Chukwugoziem Bright
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Factors Associated ◽  
Artery Disease

Background: coronary artery disease is one of the most common types of cardiovascular disorder and it occurs when the coronary artery that supply blood to the heart muscle is compromised due to the accumulation of materials such as plaque/cholesterol atherosclerosis risk factors associated with coronary artery disease   men are susceptible at 45, women at 55 include age, gender, genetics, etc, Objective: To identify the patients at elevated risk for CAD, To identify patients required further investigation to confirm the diagnosis of CAD, To describe a management plan including lifestyle changes, medications, psychosocial support, cardiac rehabilitation, etc. Methods:  A prospective observational study was conducted for a period of 6 months, from CAD patients attending max cure hospital. The data was collected from the participants after consent. Relevant patient lifestyles and lab data were documented in the data collection form (DCF). Results: The study findings are according to parameter wise, age categorization defines that in 51-60 ranging age group 27.22% that is the highest percent affected people are observed with CAD.  Of the total number of subjects participated in the study (n=202) the gender-wise comparison males (144) are more than females (58).To observe patient region, urban people (68%) are mostly affected with CAD than rural people (32%). To identify risk factors of CAD, patients with DM (34.67%), HTN (23%), smoking (17.32%), alcohol (25.74%), and obesity (13.86%) are the major risk factors associated with CAD. Based on family history a total of 21 members were identified out of 202, among them with CAD were 7, with CKD were 6, with HTN were 5 and with DM were 3 members respectively.  According to the past history in a total of 202 members, patients with Cerebrovascular accidents were 4, patients with MI/UA were 20, and CKD were 4 respectively. Conclusion: Evaluation of risk factors in patients with coronary artery disease in a tertiary care hospital was observed. Age, Diabetes mellitus, Hypertension, Smoking, Alcohol, and Obesity are more causing risk factors than others.

scholarly journals Active Surveillance of Carbapenem-resistant Gram-negative Bacteria to guide antibiotic therapy: a single-center prospective observational study

2021 ◽  
Author(s):  
Qiqiang Liang ◽  
Juan Chen ◽  
Yongshan Xu ◽  
Yibing Chen ◽  
Man Huang
Keyword(s):  
Risk Factors ◽  
Observational Study ◽  
Antibiotic Therapy ◽  
Prospective Observational Study ◽  
Gram Negative Bacteria ◽  
Empirical Antibiotic Therapy ◽  
Single Center ◽  
Gram Negative ◽  
Factors Associated ◽  
Carbapenem Resistant

Abstract Background Carbapenem-resistant Gram-negative Bacteria (CRGNB) have become a public health concern worldwide. The risk factors associated with CRGNB infection after colonization are unknown, nor is the optimal timing of antibiotic treatment, warranting further investigation. Methods A 4-year single-center prospective observational study was conducted. CRGNB-colonized patients were incorporated on admission into our observation cohort for an active surveillance culture program, and analysis of risk factors associated with infections after CRGNB colonization was performed. We divided patients into empirical antibiotic therapy groups and standard antibiotic therapy groups according to whether antibiotics were used before or after cultures yielded a result to explore the relationship between the timing of antibiotics and clinical efficacy. Results 152 out of 451 CRGNB-colonized patients in the prospective observational cohort developed CRGNB infection. The risk factors associated with CRGNB infection after colonization included CRKP (P < 0.001, OR = 3.27) and CRPA (P < 0.001, OR = 2.97) colonization, history of carbapenems use (P < 0.001, OR = 5.48), and immunocompromise (P < 0.001, OR = 7.07). There were 88 infected patients in the empirical antibiotic therapy groups and 64 in standard antibiotic therapy groups. The mortality was lower in empirical therapy groups than standard therapy groups (17.0% vs. 37.5%, P = 0.004, OR = 0.32). Conclusions CRGNB colonization increased the risk of infection, and risk factors included CRKP and CRPA colonization, immunocompromise, and prior carbapenems use. Once infection occurs in CRGNB-colonized patients, susceptibility-guided antibiotic treatment can be given according to previous susceptibility results of colonized CRGNB, reducing mortality.

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