scholarly journals Changes in PHQ-9 depression scores in acute stroke patients shortly after returning home

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0259806
Author(s):  
Brent Strong ◽  
Michele C. Fritz ◽  
Liming Dong ◽  
Lynda D. Lisabeth ◽  
Mathew J. Reeves
Keyword(s):  
Depressive Symptoms ◽  
Acute Stroke ◽  
Recovery Period ◽  
Stroke Severity ◽  
Stroke Survivors ◽  
Stroke Patients ◽  
Early Recovery ◽  
Post Stroke ◽  
Early Recovery Period ◽  
Over Time

Introduction Post-stroke depression is a disabling condition that occurs in approximately one-third of stroke survivors. There is limited information on changes in depressive symptoms shortly after stroke survivors return home. To identify factors associated with changes in post-stroke depressive symptoms during the early recovery period, we conducted a secondary analysis of patients enrolled in a clinical trial conducted during the transition period shortly after patients returned home (MISTT). Methods The Michigan Stroke Transitions Trial (MISTT) tested the efficacy of social worker case management and access to online information to improve patient-reported outcomes following an acute stroke. Patient Health Questionnaire-9 (PHQ-9) scores were collected via telephone interviews conducted at 7 and 90 days post-discharge; higher scores indicate more depressive symptoms. Generalized estimating equations were used to identify independent predictors of baseline PHQ-9 score at 7 days and of changes over time to 90 days. Results Of 265 patients, 193 and 185 completed the PHQ-9 survey at 7 and 90 days, respectively. The mean PHQ-9 score was 5.9 at 7 days and 5.1 at 90 days. Older age, being unmarried, and having moderate stroke severity (versus mild) were significantly associated with lower 7-day PHQ-9 scores (indicating fewer depressive symptoms). However, at 90 days, both unmarried patients and those with moderate or high stroke severity had significant increases in depressive symptoms over time. Conclusions In stroke patients who recently returned home, both marital status and stroke severity were associated with depressive symptom scores; however, the relationships were complex. Being unmarried and having higher stroke severity was associated with fewer depressive symptoms at baseline, but both factors were associated with worsening depressive symptoms over time. Identifying risk factors for changes in depressive symptoms may help guide effective management strategies during the early recovery period.

scholarly journals Efficiency of Leg Exoskeleton Use in Rehabilitation of Cerebral Stroke Patients

2021 ◽  
Vol 22 (3) ◽  
pp. 257-264
Author(s):  
Sergey V. Kotov ◽  
Alexander I. Romanov ◽  
Ekaterina V. Silina ◽  
Victor A. Stupin ◽  
Elena V. Isakova ◽  
...  
Keyword(s):  
Recovery Period ◽  
Rehabilitation Program ◽  
Control Group ◽  
Cerebral Stroke ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Early Recovery ◽  
Lower Limb Exoskeleton ◽  
Group 2 ◽  
Early Recovery Period

Abstract The study aimed to evaluate the effectiveness of functional and motor activity restoration, including the walking function, in patients after an ischemic stroke using the ExoAtlet lower limb exoskeleton. Patients and methods. A clinical study was carried out on 42 patients who had undergone a cerebral infarction in the mid cerebral artery system with a post-stroke paresis of the leg, and who had undergone a rehabilitation course in a round-theclock hospital during the early recovery period. Patients were randomized into two equal groups comparable in terms of the stroke severity: the patients in group 1 were receiving a standard rehabilitation program (control group), the patients in group 2 were additionally receiving a course of gait rehabilitation using the ExoAtlet exoskeleton - 10 sessions, 5 sessions per week for 14 days. Results. The study demonstrated the effectiveness of the ExoAtlet exoskeleton used in the rehabilitation of stroke patients over the standard course of rehabilitation. The advantages include a decrease in the hemiparesis degree, an increase in the muscle strength of the paretic limb, an improvement in balance, an improvement and acceleration of the walking process. The obtained results of the instrumental study confirmed the benefits of physical training on the Exoskeleton, which was demonstrated through an increase in stability and balance, as well as through a decrease in the energy consumption index for maintaining the stable verticalization. Conclusion. The usage of the ExoAtlet exoskeleton increases the effectiveness of rehabilitation measures and improves motor and functional activities of patients who have suffered a cerebral stroke.

scholarly journals The effectiveness of using modern technologies in early recovery period treatment of post-stroke patients

2018 ◽  
Vol 9 (1) ◽  
pp. 10-17
Author(s):  
Z. M. Mizieva ◽  
E. V. Shirshova
Keyword(s):  
Treatment Effectiveness ◽  
Recovery Period ◽  
Motor Dysfunction ◽  
Upper Limbs ◽  
Stroke Patients ◽  
Early Recovery ◽  
Post Stroke ◽  
Early Recovery Period ◽  
Positive Effect ◽  
Modern Technologies

This study presents the results of investigation «Amadeo», «Armeo» effectiveness in treatment of 61 post-stroke patients during early recovery period with upper limbs motor dysfunction. Comparative characteristics of treatment effectiveness in patients with ischemic and hemorrhage stroke are given. The results of investigation represent positive effect of using robotic technologies in post stroke patients rehabilitation therapy.

Neurorehabilitation in the Early Recovery Period of Ischemic Stroke. Pharmacology Support

2021 ◽  
Vol 63 (1) ◽  
pp. 22-25
Author(s):  
Denys N. Khramtsov ◽  
Olexandr N. Stoyanov ◽  
Tetiana N. Muratova ◽  
Olexandr R. Pulyk
Keyword(s):  
Ischemic Stroke ◽  
Acute Stroke ◽  
Recovery Period ◽  
Rehabilitation Medicine ◽  
Neuroprotective Agents ◽  
Early Recovery ◽  
National Medical ◽  
Cholinergic Agents ◽  
Early Recovery Period ◽  
Medical University

Aim: The aim of the study was to evaluate the clinical outcome in the use of neuroprotective agents in the acute period of ischemic stroke. Material and Methods: The study was performed on the basis of the stroke of the Center for Reconstructive and Rehabilitation Medicine (University Clinic) of the Odessa National Medical University. A retrospective analysis of clinical outcomes of 115 patients with acute stroke was conducted. Results: An average NIHSS score at discharge was 4.1±0.1 points when treated with no refinery, then it reached 3.6±0.1 points when using peptidergic drugs, and 3.4±0.1 when using D-fdf. 3.1±0.1 points. When using D-FDF, the MMSE score was 3.5±0.1 points, whereas when using cholinergic agents, this index did not exceed 26.9±1.5 points, and when using peptidergic agents - 26.8±1.4 points. Conclusion: The use of neuroprotective agents positively affects the effectiveness of neuro-rehabilitation in patients with acute stroke. The best results in three months after the hospitalization were obtained for peptidergic agents and D-fructose-1,6-diphosphate.

scholarly journals LACK OF EMPHASIS ON PSYCHOLOGICAL REHABILITATION FOR STROKE PATIENTS

2012 ◽  
Vol 1 (1) ◽  
pp. 2
Author(s):  
Samina Masood Haider
Keyword(s):  
Emotional Difficulties ◽  
Stroke Survivors ◽  
Stroke Patients ◽  
Post Stroke ◽  
Post Stroke Depression ◽  
The Many ◽  
Over Time

It has been observed that most of the patients are not aware of the dilapidating affects of post stroke depression on their recovery, survival and a return to normal activities of life. The lack of emphasis on psychological rehabilitation for stroke patients is a source of concern for me and I would like to bring to your attention about the facts regarding the implications of proper psychological rehabilitation is not undertaken. Stroke survivors report a range of emotional difficulties, most common being fear, anxiety, frustration, anger, sadness and a sense of grief for their physical and mental losses. Usually these feelings may fade over time however, some patients may struggle with adjusting to the many changes following stroke. When this happens these feelings can develop into depression. It is estimated that approximately one-third of stroke1 survivors develop post-stroke depression (PSD)

scholarly journals Post-stroke depression and the abilities of antidepressants to enhance the effectiveness of neurorehabilitation

2020 ◽  
Vol 12 (6) ◽  
pp. 110-116
Author(s):  
S. V. Kotov ◽  
E. V. Isakova ◽  
Yu. V. Egorova
Keyword(s):  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Recovery Period ◽  
Serotonin Reuptake Inhibitors ◽  
Selective Serotonin ◽  
Early Recovery ◽  
Post Stroke ◽  
Optimal Drug ◽  
Post Stroke Depression ◽  
Early Recovery Period

Stroke is the leading cause of disability in adults. Depression after a stroke is detected in one third of patients, complicating physical rehabilitation, worsening functional outcome, increasing mortality rates. The question of the use of antidepressants in the treatment of post-stroke depression is currently not completely resolved, there is no consensus on the most optimal drug. The drugs of choice are selective serotonin reuptake inhibitors, the use of tricyclic antidepressants is possible. A number of clinical studies indicate the effectiveness of selective serotonin reuptake inhibitors in the treatment of post-stroke depression, including through mechanisms including increased neuroplasticity and stimulation of neurogenesis, while others disprove their effectiveness. The article presents a clinical case of the use of vortiroxetin in the patient’s neurorehabilitation in the early recovery period of a stroke, its safety and positive effect are shown.

Abstract P206: Changes in Social Support Within the Early Recovery Period and Outcomes After Acute Myocardial Infarction

2011 ◽  
Vol 4 (suppl_1) ◽  
Author(s):  
Erica C Leifheit-Limson ◽  
Kimberly J Reid ◽  
Stanislav V Kasl ◽  
Haiqun Lin ◽  
Philip G Jones ◽  
...  
Keyword(s):  
Social Support ◽  
Depressive Symptoms ◽  
Health Status ◽  
Confidence Intervals ◽  
Repeated Measures ◽  
Short Form ◽  
Recovery Period ◽  
Early Recovery ◽  
Early Recovery Period ◽  
High Support

Background: Baseline social support is associated with outcomes after AMI. However, little is known about changes in social support during the early AMI recovery period and whether changes influence outcomes over the first year. Methods: Using data from 1951 AMI patients enrolled in the 19-center PREMIER study, we longitudinally examined whether changes in social support between baseline (index hospitalization) and 1 month post-AMI were associated with health status and depressive symptom outcomes. Using 5 items from the ENRICHD Social Support Inventory, we categorized patients into low (score <=18) and high (score >18) support and examined changes between these categories during the first month of recovery. Health status and depressive symptoms were assessed at baseline, 6, and 12 months using the Seattle Angina Questionnaire (SAQ), Short Form-12 (SF-12), and the Patient Health Questionnaire-9 (PHQ-9). Associations were evaluated using hierarchical repeated-measures regression, adjusting for site, baseline health status, depressive symptoms, and other sociodemographic and clinical factors. Results: During the first month of recovery, 5.6% of patients had persistently low support, 6.4% had worsened support, 8.1% had improved support, and 80.0% had persistently high support. In risk-adjusted analyses, patients with persistently low or worsened support (versus those with persistently high support) had greater risk of angina, worse SAQ quality of life (QOL), worse SF-12 mental component summary (MCS), and more PHQ-9 depressive symptoms ( table ). Patients with improved support had outcomes consistent with those of patients with persistently high support ( table ). Similarly, patients with worsened support had outcomes comparable to patients with persistently low support (p>0.50 for all comparisons). Conclusion: Changes in social support within the early recovery period are not uncommon and are important for predicting patient-centered outcomes. Outcome Social Support Status at 1 Month Persistently Low Worsened Improved Persistently High SAQ Angina * 1.39 (1.09, 1.78) 1.46 (1.08, 1.97) 1.13 (0.89, 1.43) reference SAQ QoL † -7.63 (-10.96, -4.30) -7.44 (-10.54, -4.34) -0.85 (-3.49, 1.80) reference SF-12 PCS † -0.14 (-2.20, 1.91) -0.20 (-2.14, 1.73) -0.44 (-2.07, 1.18) reference SF-12 MCS † -5.63 (-7.33, -3.92) -4.82 (-6.42, -3.22) -1.54 (-2.88, -0.20) reference PHQ-9 † 2.29 (1.51, 3.06) 1.94 (1.22, 2.66) 0.81 (0.19, 1.43) reference * Estimates correspond to relative risks (95% confidence intervals) of any angina (SAQ Angina Score <100). † Estimates correspond to beta values (95% confidence intervals).

scholarly journals A Study of Biofeedback Gait Training in Cerebral Stroke Patients in the Early Recovery Phase with Stance Phase as Target Parameter

Sensors ◽  
2021 ◽  
Vol 21 (21) ◽  
pp. 7217
Author(s):  
Dmitry V. Skvortsov ◽  
Sergey N. Kaurkin ◽  
Galina E. Ivanova
Keyword(s):  
Stance Phase ◽  
Recovery Period ◽  
Biomechanical Analysis ◽  
Control Group ◽  
Cerebral Stroke ◽  
Stroke Patients ◽  
Early Recovery ◽  
Phase Duration ◽  
Gait Symmetry ◽  
Early Recovery Period

Walking function disorders are typical for patients after cerebral stroke. Biofeedback technology (BFB) is currently considered effective and promising for training walking function, including in patients after cerebral stroke. Most studies recognize that BFB training is a promising tool for improving walking function; however, the data on the use of highly selective walking parameters for BFB training are very limited. The aim of our study was to investigate the feasibility of using BFB training targeting one of the basic parameters of gait symmetry—stance phase duration—in cerebral stroke patients in the early recovery period. The study included 20 hemiparetic patients in the early recovery period after the first hemispheric ischemic stroke. The control group included 20 healthy subjects. The BFB training and biomechanical analysis of walking (before and after all BFB sessions) were done using an inertial system. The mean number of BFB sessions was nine (from 8 to 11) during the three weeks in clinic. There was not a single negative response to BFB training among the study patients, either during the sessions or later. The spatiotemporal parameters of walking showed the whole syndrome complex of slow walking and typical asymmetry of temporal walking parameters, and did not change significantly as a result of the study therapy. The changes were more significant for the functioning of hip and knee joints. The contralateral hip amplitude returned to the normal range. For the knee joint, the amplitude of the first flexion increased and the value of the amplitude of hyperextension decreased in the middle of the stance phase. Concerning muscle function, the observed significant decrease in the function of m. Gastrocnemius and the hamstring muscles on the paretic side remained without change at the end of the treatment course. We obtained positive dynamics of the biomechanical parameters of walking in patients after the BFB training course. The feasibility and efficacy of their use for targeted correction need further research.

scholarly journals POST-STROKE DEPRESSION (MODERN LOOK AT THE PROBLEM AND OWN RESEARCH)

2020 ◽  
Vol 6 (1-2) ◽  
pp. 10-19
Author(s):  
O.P. Onopriyenko
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Functional Dependence ◽  
Recovery Period ◽  
Stroke Patients ◽  
Early Recovery ◽  
Post Stroke ◽  
Post Stroke Depression ◽  
The Impact

The high incidence and increase in disability among the population after a stroke is a topical problem worldwide in the second decade of the 21st century. Brain strokes, their complications (dementias, depression), place a heavy burden on the society of the country, the families of patients. Objective: To investigate the impact of psychogenic factors on the epidemiology of stroke in Brоvаry district of Kyiv region for the last 10 years, to compile statistics and to compare them with world and regional data of Kyiv region and Ukraine. Methods. The resources of PubMed (1990-2016) and UpToDate (2016) were used to write the review article. To address these issues and to improve the quality of care provided to patients in the Kyiv region, Brovary and Brovary district, an epidemiological study of stroke patients and its risk factors has been continued. We screened 771 patients with stroke in the angioneurology department of the Brоvаry Multidisciplinary Clinical Hospital of the Kyiv region for psycho-emotional depressive disorders in the acute and late recovery period of ischemic stroke using NIHSS scales, Bartel index, modified Rankin scale, RASS scale. Statistical analysis of the obtained data was performed using the Spearman correlation coefficient, multiple regression analysis, descriptive statistics methods. Results. The risk factors for depression in the early recovery period after ischemic stroke and the association of post-stroke depression (PSD) with the risk of recurrence have been identified. 771 stroke patients (13%) had anxiety-depressive syndrome: 436 (56%) man, 335 (44%) women. PSD has been found to be more pronounced in old people, female, single patients. The development of PSD is influenced by many factors, including severity of stroke, disease course, significant functional impairment and degree of disability, reduced cognitive, language functions, and dependence on outsiders. The more pronounced severity of PSD is related to the degree of functional dependence and language-cognitive status. Conclusions. The presence of PSD results in worst prognosis of stroke of functional and cognetiv renewal of patients, increases their dependence on an extraneous help, considerably worsens quality of life. The origin of PSD has multifactorial genesis, mostly psychogenicsocial factor, influences on the degree of functional dependence of patients, especially aphasia. Influence on risk factors will give an opportunity to prevent development of PSD will promote it to effective rehabilitation and prevantion of repeated ischemic stroke. Keywords: ischemic stroke, psychogenic factors, post-stroke depression, principles of rehabilitation, treatment, prevention.

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