scholarly journals Nationwide Multicentric Retrospective and Prospective Epidemiologic Survey of Bisphosphonate-related Osteonecrosis of the Jaws

2020 ◽  
Author(s):  
Tamás Vereb
Keyword(s):  
Data Collection ◽  
Maxillofacial Surgery ◽  
Data Entry ◽  
Study Data ◽  
Bisphosphonate Therapy ◽  
Point Of View ◽  
Oral And Maxillofacial Surgery ◽  
Osteonecrosis Of The Jaws ◽  
Epidemiologic Survey ◽  
Set Up

Introduction: Bisphosphonate-related osteonecrosis of the jaws is considered to be a rare but severe complication of bisphosphonate therapy. The presumably multifactorial pathomechanisms of medication-related osteonecrosis of the jaws have not been fully elucidated so far. To understand this condition better data collection is essential. Although the number of scientific papers about this subject is large, only a few multicenter reports have been published. Management of this serious side effect is a real challenge and requires a multidisciplinary approach. Material and methods: We present a novel cloud-based data collection system for the evaluation of the risk factors of bisphosphonate-related osteonecrosis of the jaws. Web-based questionnaire and database have been set up and made available to voluntary researchers and clinicians in oral and maxillofacial surgery in Hungary and Slovakia. Results: To date, fifteen colleagues from eight maxillofacial units have joined the study. Data of 180 patients have been recorded. Collected data were statistically analysed and evaluated from an epidemiological point of view. Discussions: Authors consider cloud-based multicenter data collection a useful tool that allows for real-time collaboration between users, facilitates fast data entry and analysis, and thus considerably contributes to widening our knowledge of bisphosphonate-related osteonecrosis of the jaws. Conclusions: Although several issues are still open regarding the management of the disorder, this study may help to develop evidence-based, individualized, stage-adapted therapeutic strategies that will replace the previous empirical treatment.

scholarly journals Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population

2020 ◽  
Vol 9 (2) ◽  
pp. 426 ◽  
Author(s):  
Tamás Vereb ◽  
Krisztina Boda ◽  
László Czakó ◽  
Mihály Vaszilkó ◽  
Gábor Fülöp ◽  
...  
Keyword(s):  
Data Collection ◽  
Maxillofacial Surgery ◽  
Data Entry ◽  
European Population ◽  
Study Data ◽  
Bisphosphonate Therapy ◽  
Point Of View ◽  
Oral And Maxillofacial Surgery ◽  
Osteonecrosis Of The Jaws ◽  
Set Up

Objective: Bisphosphonate-related osteonecrosis of the jaws is considered to be a rare but severe complication of bisphosphonate therapy. To understand this condition better, data collection is essential. Although the number of scientific papers about this subject is large, to date only a few multicenter reports have been published. Study design: We present a novel cloud-based data collection system for the evaluation of the risk factors of bisphosphonate-related osteonecrosis of the jaws. Web-based questionnaire and database have been set up and made available to voluntary researchers and clinicians in oral and maxillofacial surgery in Hungary and Slovakia. Results: To date, fifteen colleagues from eight maxillofacial units have joined the study. Data of 180 patients have been recorded. Collected data were statistically analysed and evaluated from an epidemiological point of view. Conclusions: Authors consider cloud-based multicenter data collection a useful tool that allows for real-time collaboration between users, facilitates fast data entry and analysis, and thus considerably contributes to widening our knowledge of bisphosphonate-related osteonecrosis of the jaws.

Osteonecrosis of the Jaws Secondary to Bisphosphonate Therapy: A Case Series

2008 ◽  
Vol 9 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Satish K. S. Kumar ◽  
Michael C. Meru ◽  
Parish P. Sedghizadeh
Keyword(s):  
Maxillofacial Surgery ◽  
Case Series ◽  
Poor Quality ◽  
Bisphosphonate Therapy ◽  
Oral And Maxillofacial Surgery ◽  
Osteonecrosis Of The Jaws ◽  
Cancer Metastases ◽  
Dental Procedures ◽  
Southern California School ◽  
School Of Dentistry

Abstract Aim The objective of this report is to present the clinical experiences of several patients affected with osteonecrosis (ONJ) secondary to bisphosphonate (BP) therapy and to provide a discussion of the specific BPs implicated in this condition. Background ONJ secondary to BP therapy is becoming an increasingly reported complication following dental therapy. This is particularly true of surgical dental procedures such as extractions. BPs are a class of pharmaceuticals used in the treatment of numerous disorders affecting bone, including osteoporosis, cancer metastases to bone, hypercalcemia of malignancy, and multiple myeloma. Although ONJ is a more recently described phenomenon, it is an emerging problem that may be associated with significant morbidity such as oral dysfunction, impaired eating ability, pain, and compromised esthetics resulting in a poor quality of life in affected patients. Case Report This is a description of 13 patients affected with ONJ secondary to BP therapy managed at the Orofacial Pain & Oral Medicine Center, Special Patients Clinic, and Oral and Maxillofacial Surgery Clinic at the University of Southern California, School of Dentistry between October 2005 and April 2007, with a discussion of the specific BPs implicated in this condition, the clinical presentation, management, and follow-up. Summary Thorough reporting of every case of ONJ is important to help advance the understanding of this poorly understood condition. The authors’ approach to care represents a more conservative mode to management than previously described by many investigators. Citation Kumar SKS, Meru MC, Sedghizadeh PP. Osteonecrosis of the Jaws Secondary to Bisphosphonate Therapy: A Case Series. J Contemp Dent Pract 2008 January;(9)1:063-069.

scholarly journals Bisphosphonate-associated Osteonecrosis of the Jaws: a Survey of the Level of Knowledge of Dentists about the Risks of Bisphosphonate Therapy

Folia Medica ◽  
2019 ◽  
Vol 61 (2) ◽  
pp. 303-311
Author(s):  
Meri A. Hristamyan-Cilev ◽  
Petya P. Pechalova ◽  
Ralitsa D. Raycheva ◽  
Veselka P. Hristamyan ◽  
Ani K. Kevorkyan ◽  
...  
Keyword(s):  
Side Effects ◽  
Maxillofacial Surgery ◽  
Pediatric Dentistry ◽  
Bisphosphonate Therapy ◽  
Oral And Maxillofacial Surgery ◽  
Osteonecrosis Of The Jaws ◽  
Dental Practitioners ◽  
Level Of Knowledge ◽  
Effect Of Treatment ◽  
Insufficient Knowledge

Abstract Introduction: Bisphosphonate-associated osteonecrosis of the jaws (BAONJ) is a side effect of treatment with bisphosphonate (BP). Reports of this complication have increased recently. Aim: To evaluate the level of knowledge of dentists from Plovdiv, Bulgaria, about possible complications of bisphosphonate therapy of patients in dental practice. Materials and methods: Three hundred and twenty-three dental practitioners from Plovdiv, Bulgaria, took part in an anonymous survey containing 25 questions, designed to evaluate the knowledge of dentists about the complications of BP therapy. Results: Oral and maxillofacial surgeons have the best knowledge about the indications and side effects of BP therapy, while dentists with a specialty in Pediatric Dentistry and General Dentistry have insufficient knowledge. Of the respondents, 17.03% are absolutely uninformed about BP and their side effects, and 1/2 declare that they have never had a patient with complications from BP therapy in their practice, probably due to a lack of awareness of the problem. Approximately half of the dentists we surveyed agree to carry out prophylactic examinations of patients receiving BP and know what the prophylactic examination includes. Only 15.48% of the respondents have correctly responded that in order to be treated as clinically healthy, patients should have stopped taking BP for more than 10 years. Conclusion: With the exception of specialists in Oral and Maxillofacial Surgery, dental practitioners in Plovdiv and the region are poorly informed about the complications associated with BP therapy. Therefore, efforts must be made to make these dentists better informed about BAONJ, especially about the methods and means of preventing this condition.

scholarly journals Lower Lip Reconstruction Using Unilateral Nasolabial Gate Flap (Fujimori Technique)

2013 ◽  
Vol 59 (1) ◽  
pp. 40-43 ◽  
Author(s):  
Alina Iacob ◽  
Bálint Bögözi
Keyword(s):  
Maxillofacial Surgery ◽  
Point Of View ◽  
Medium Size ◽  
Oral And Maxillofacial Surgery ◽  
Reconstructive Procedures ◽  
Lower Lip ◽  
Lip Reconstruction ◽  
Oncological Treatment ◽  
Level I ◽  
The Aesthetic

Abstract Background: In the medical literature there are multiple reconstructive procedures for small and medium size defects of the lower lip, but only a few methods for larger defects involving the whole lower lip. Choosing the repairing procedure for larger lower lip defects must take into account two aspects: flap or flaps used should be local flaps, and suture lines should correspond to the natural facial creases or follow the functional lines of different facial aesthetic units. Finally, the flap or flaps should be large enough to restore the entire postexcisional defect. However, the more tissue is lost from the lower lip, the more challenging the reconstruction is from a functional and cosmetic point of view. Material and methods: During the last 2 years in the Oral and Maxillofacial Surgery Department of the County Emergency Clinical Hospital in Tîrgu Mureș, the unilateral Fujimori technique has been successfully used for the reconstruction of large lower lip defects in 4 patients with extended, neglected squamous cell carcinomas involving almost the whole lower lip tissue. These patients underwent complex surgical and oncological treatment. Surgery was performed in two stages: first, excision of the tumor and immediate lip reconstruction, and then removal of submandibular lymph nodes (level I), in the second stage. Results: The aesthetic and functional recovery of these patients was very good, with no need of other subsequent surgical corrections. Conclusions: The postoperative reconstruction of large defects of the lower lip is far from optimal, but it is very important to restore an adequate muscle function, the lip continence and a satisfactory facial appearance.

Evolution of Aesthetic Dentistry

2019 ◽  
Vol 98 (12) ◽  
pp. 1294-1304 ◽  
Author(s):  
M.B. Blatz ◽  
G. Chiche ◽  
O. Bahat ◽  
R. Roblee ◽  
C. Coachman ◽  
...  
Keyword(s):  
Dental Treatment ◽  
Maxillofacial Surgery ◽  
Dental Materials ◽  
Specific Treatment ◽  
Point Of View ◽  
Treatment Modalities ◽  
Oral And Maxillofacial Surgery ◽  
The Past ◽  
Science And Art ◽  
Aesthetic Dentistry

One of the main goals of dental treatment is to mimic teeth and design smiles in a most natural and aesthetic manner, based on the individual and specific needs of the patient. Possibilities to reach that goal have significantly improved over the last decade through new and specific treatment modalities, steadily enhanced and more aesthetic dental materials, and novel techniques and technologies. This article gives an overview of the evolution of aesthetic dentistry over the past 100 y from a historical point of view and highlights advances in the development of dental research and clinical interventions that have contributed the science and art of aesthetic dentistry. Among the most noteworthy advancements over the past decade are the establishment of universal aesthetic rules and guidelines based on the assessment of natural aesthetic parameters, anatomy, and physiognomy; the development of tooth whitening and advanced restorative as well as prosthetic materials and techniques, supported by the pioneering discovery of dental adhesion; the significant progress in orthodontics and periodontal as well as oral and maxillofacial surgery; and, most recently, the implementation of digital technologies in the 3-dimensional planning and realization of truly natural, individual, and aesthetic smiles. In the future, artificial intelligence and machine learning will likely lead to automation of aesthetic evaluation, smile design, and treatment-planning processes.

scholarly journals Perkembangan Pariwisata Di Daya Tarik Wisata Pantai Berawa Kabupaten Badung

2019 ◽  
Vol 6 (2) ◽  
pp. 309
Author(s):  
I Made Dipadewanda ◽  
I Gusti Agung Oka Mahagangga
Keyword(s):  
Data Analysis ◽  
Data Collection ◽  
Data Reduction ◽  
Qualitative Data ◽  
Point Of View ◽  
Local Society ◽  
Analysis Technique ◽  
Collection Data ◽  
Set Up ◽  
The Impact

The research is conducted in Banjar Berawa/Desa Adat Berawa, nort Kuta district, Badung Regency. The study purposes to know the impact of tourism growth to the society consumptive pattern in Berawa. The technique of the data collection use direct observation technique to the location, interviewing for informan, I.E.Bendesa Adat Berawa, Klian Desa Berawa, Klian Dinas Berawa, Klian Subak Tibubeneng Village, Local society, and documentation by taking photos. The data are analysed by using qualitative data analysis technique which are working based on data, searching and finding pattern, getting interesting data and deciding the data that will be ssuced. The technique of informants assigmnen is purposive sampling which is assigning the sample by using particular consideration so, deserves to be a sample. The data analysis includes with collection data, reduction data, displaying data, conclusion and  verivication. The result of the study shows the society point of view to the aconomy establishmemt of educational aspec of the society which is getting increase, society in Banjar Berawa are also starting to enterpreneurship by set up abussiness such as homestay and laundy. The point of view of society to the customary order is the society seens strong with the wealth that they have. The society fulfill their family neededs by taking many kends of occupation.  Keywords :Impact, tourism, consumptionpattern, society

scholarly journals Practical Guidelines for the Prevention, Diagnosis, and Treatment of Osteonecrosis of the Jaw in Patients With Cancer

2006 ◽  
Vol 2 (1) ◽  
pp. 7-14 ◽  
Author(s):  
Salvatore Ruggiero ◽  
Julie Gralow ◽  
Robert E. Marx ◽  
Ana O. Hoff ◽  
Mark M. Schubert ◽  
...  
Keyword(s):  
Risk Factors ◽  
Health Care Professionals ◽  
Multidisciplinary Treatment ◽  
Maxillofacial Surgery ◽  
Osteonecrosis Of The Jaw ◽  
Bisphosphonate Therapy ◽  
Oral And Maxillofacial Surgery ◽  
Patients With Cancer ◽  
Dental Procedures ◽  
Practical Guidelines

PurposeThis article discusses osteonecrosis of the jaw (ONJ) and offers health care professionals practical guidelines and recommendations for the prevention, diagnosis, and management of ONJ in cancer patients receiving bisphosphonate treatment.MethodsA panel of experts representing oral and maxillofacial surgery, oral medicine, endocrinology, and medical oncology was convened to review the literature and clinical evidence, identify risk factors for ONJ, and develop clinical guidelines for the prevention, early diagnosis, and multidisciplinary treatment of ONJ in patients with cancer. The guidelines are based on experience and have not been evaluated within the context of controlled clinical trials.ResultsONJ is a clinical entity with many possible etiologies; historically identified risk factors include corticosteroids, chemotherapy, radiotherapy, trauma, infection, and cancer. With emerging concern for potential development of ONJ in patients receiving bisphosphonates, the panel recommends a dental examination before patients begin therapy with intravenous bisphosphonates. Dental treatments and procedures that require bone healing should be completed before initiating intravenous bisphosphonate therapy. Patients should be instructed on the importance of maintaining good oral hygiene and having regular dental assessments. For patients currently receiving bisphosphonates who require dental procedures, there is no evidence to suggest that interrupting bisphosphonate therapy will prevent or lower the risk of ONJ. Frequent clinical assessments and conservative dental management are suggested for these patients. For treatment of patients who develop ONJ, a conservative, nonsurgical approach is strongly recommended.ConclusionAn increased awareness of the potential risk of ONJ in patients receiving bisphosphonate therapy is needed. Close coordination between the treating physician and oral surgeon and/or a dental specialist is strongly recommended in making treatment decisions.

Accessibility to editorial information in Oral and Maxillofacial Surgery journals: The authors' point of view

2015 ◽  
Vol 43 (7) ◽  
pp. 1078-1081 ◽  
Author(s):  
Pablo Castelo-Baz ◽  
Yago Leira-Feijoo ◽  
Juan Manuel Seoane-Romero ◽  
Pablo Varela-Centelles ◽  
Juan Seoane
Keyword(s):  
Maxillofacial Surgery ◽  
Point Of View ◽  
Oral And Maxillofacial Surgery ◽  
Surgery Journals

scholarly journals Perbandingan Kehadiran Sosial dalam Pembelajaran Daring Menggunakan Whatsapp groupdan Webinar Zoom Berdasarkan Sudut Pandang Pembelajar Pada Masa Pandemic COVID-19

2020 ◽  
Vol 3 (2) ◽  
pp. 331-341 ◽  
Author(s):  
Eko Yulianto ◽  
Putri Dwi Cahyani ◽  
Sofia Silvianita
Keyword(s):  
Online Learning ◽  
Data Collection ◽  
Financial Institutions ◽  
Social Presence ◽  
Study Data ◽  
Research Data ◽  
Point Of View ◽  
Descriptive Statistics ◽  
Student Preferences ◽  
Accounting Courses

Penelitian ini bertujuan untuk membandingkan kehadiran sosial dalam pembelajaran daring menggunakan whatsapp groupdan webinar Zoom, serta mengetahui preferensi mahasiswa terhadap kedua media pembelajaran tersebut. Pengumpulan data dalam penelitian ini menggunakan instrument non tes dalam bentuk kuisioner dengan skala likert yang diadaptasi dari Tantri, 2018 untuk mengukur 2 (dua) aspek kehadiran sosial yaitu aspek keterhubungan dan aspek pembelajaran. Data diperoleh dari 50 mahasiswa Universitas Sarjanawiyata Tamansiswa program studi akuntansi yang mengambil mata kuliah Bank dan Lembaga keuangan lainnya dan telah mengikuti perkuliahan sesuai jadwal menggunakan whatsapp groupmaupun webinar Zoom selama masa pandemi Covid-19. Data penelitian dianalisis menggunakan statistika deskriptif yaitu: mean (rata-rata) dan persentase. Hasil penelitian menunjukkan bahwa aspek keterhubungan dan aspek pembelajaran pada pembelajaran daring menggunakan whatsapp groupmenurut sudut pandang mahasiswa lebih tinggi dibandingkan dengan menggunakan webinar Zoom. Selain itu, 98% mahasiswa lebih memilih menggunakan whatsapp groupuntuk digunakan dalam pembelajaran daring pada masa pandemi Covid-19. Abstract: The purpose of this study was to compare social attendance in online learning using the Whatsapp groupand Zoom webinar and determine student preferences for the two learning media. In this study, data collection uses non-test instruments in the form of questionnaires with a Likert scale adapted from Tantri (2018), to measure 2 (two) aspects of social presence, namely aspects of connectedness and learning aspects. Data obtained from 50 Sarjanawiyata Tamansiswa University undergraduated students who took accounting courses in Banks and other financial institutions and attended classes on a schedule using WhatsApp groups or Zoom webinar during the Covid-19 pandemic. The research data were analyzed using descriptive statistics, namely: mean (average) and percentage. The results showed that the connectedness and learning aspects of online learning using the Whatsapp groupaccording to the student's point of view were higher than using Zoom webinar. Also, 98% of students prefer WhatsApp groups to be used in online learning during the Covid-19 pandemic.

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