scholarly journals Clinical Study on Ocular Manifestations in Patients with Psoriasis, in Chennai, India

2021 ◽  
Vol 10 (23) ◽  
pp. 1766-1771
Author(s):  
Anandhalakshmi Subramanian ◽  
Suhas Prabhakar ◽  
Joshmitha M.S. ◽  
Gowtham Kim
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Test Results ◽  
Health Care Centre ◽  
Ocular Manifestations ◽  
Asymptomatic Patients ◽  
Scalp Psoriasis ◽  
Evaporative Dry Eye ◽  
Background History ◽  
Time Test

BACKGROUND We wanted to determine the prevalence of ocular manifestations assess the frequency and distribution of potential sight threatening complications in patients with psoriasis. METHODS This is a non interventional, observational hospital based study conducted at a tertiary health care centre which included 105 patients with psoriasis. A background history was taken regarding the duration of psoriasis and treatment taken. The prevalence of ocular manifestations were assessed by detailed ocular examination which involved the best corrected visual acuity using Snellen’s chart, examination of the anterior chamber using slit lamp, examination of the fundus, intraocular pressure measurement, dry eye evaluation including Schirmer’s test, tear film break up time test, and Rose Bengal stain test. RESULTS In total 105 patients with psoriasis were enrolled in this study. Among the 105 patients whose 210 eyes were examined, 77 % had psoriasis vulgaris, 14 % had scalp psoriasis, and 9 % had palmoplantar psoriasis. Among the 105 patients, 38 patients had symptomatic ocular manifestations. Out of the 38 % patients with symptomatic ocular manifestations, we found that 28 %, 25 %, 17 %, 2 % of the patients manifested with evaporative dry eye, blepharoconjunctivitis, redness and episcleritis respectively. CONCLUSIONS In our study, ocular manifestations were even seen among the asymptomatic patients. Hence a multi-disciplinary approach including effective screening and early detection of ocular manifestations followed by prompt treatment is essential to reduce the morbidity in patients with psoriasis. KEY WORDS Psoriasis, Dry Eye, Uveitis

Impact of Nanostructured Lipid Carriers as an Artificial Tear Film in a Rabbit Evaporative Dry Eye Model

Cornea ◽  
2019 ◽  
Vol 38 (4) ◽  
pp. 485-491 ◽  
Author(s):  
Pattravee Niamprem ◽  
Pronnarin Teapavarapruk ◽  
Sangly P. Srinivas ◽  
Waree Tiyaboonchai
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Nanostructured Lipid Carriers ◽  
Artificial Tear ◽  
Eye Model ◽  
Evaporative Dry Eye

scholarly journals Smoking as Risk Factors to Dry Eye Syndrome

2019 ◽  
Vol 15 (1) ◽  
pp. 1-5
Author(s):  
Alteriana Mydriati Sita Pritasari ◽  
Soraya Nur Faida ◽  
Siti Thomas Zulaikhah
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Test Results ◽  
Exclusion Criteria ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Cross Sectional Design ◽  
Schirmer I Test

Cigarette smoke can damage the fat layer of the tear film lperoxidation. Dry eye syndromeis a cluster of disorders caused by an imbalance between production and excretionof tears, causing symptoms of discomfort in the eye. This study aims to related riskfactors smoke of dry eye syndrome. Analytic observational with cross sectional design,population of all visitors, officers and employees KAI Poncol station Semarang. Sampleof 60 respondents who meet the inclusion and exclusion criteria. Data about dry eye syndrome are examined using Schirmer I test, data on smoking were taken using a checklist.The data obtained were analyzed using chi-square test. Results of the respondentswho smoke and have dry eye syndrome was higher (80.6%) compared with non-smokers(25.0%). The results chi-square test p=0.000 (p<0.05), PR = 3.222 (95%CI:1.582-6.562).Smoke who risk 3.222 times higher chance of developing dry eye syndrome comparedwith do not smoke.

scholarly journals DRY EYE STATUS BASED ON THE SCHIRMER TEST AND TEAR FILM BREAK UP TIME RESULTS FOLLOWING USE OF SOFT CONTACT LENS IN KERALA

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr. Simon George
Keyword(s):  
Dry Eye ◽  
Contact Lens ◽  
Tear Film ◽  
Test Results ◽  
Schirmer Test ◽  
Soft Contact ◽  
Soft Contact Lens ◽  
Break Up

Prospective two years study of the dry eye status following use of soft contact lens. Based on the Schirmer test results, 10 % soft contact lens wearers developed mild dry eye at the end of 1 year and 15 % developed mild dry eye at the end of 2 years. No patient had moderate or severe dry eye. Based on the Tear film break up time results, 17 % soft contact lens wearers developed mild dry eye at the end of 1 year and 30 % developed mild dry eye at the end of 2 years. 1% had moderate dry eye at the end of 2 years. No patient had severe dry eye. Keywords: Schirmer test, Tear film break up time, soft contact lens, dry eye

A Systematic Approach to Dry Eye using LipiFlow Treatment

2014 ◽  
Vol 07 (02) ◽  
pp. 104 ◽  
Author(s):  
Mitchell A Jackson ◽  
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Inflammatory Markers ◽  
Systematic Approach ◽  
Tear Film ◽  
Meibomian Gland ◽  
Diagnostic Methods ◽  
Therapeutic Options ◽  
Eye Disease ◽  
Evaporative Dry Eye

The complex strategy to understanding dry eye syndrome has led to a widespread change in approaching this condition as an ocular surface disease, stratified as evaporative dry eye, aqueous deficient dry eye, and ocular allergy. The diagnostic armamentarium has vastly expanded to include tear osmolarity and inflammatory markers as redefined by the new International Dry Eye WorkShop (DEWS) in 2007. The Tear Film & Ocular Surface Society (TFOS) panel on meibomian gland dysfunction (MGD) further expanded the interpretation of evaporative dry eye and its therapeutic options, including the newest US Food and Drug Administration (FDA)-approved device known as LipiFlow Thermal Pulsation System. This paper will give an overview on understanding dry eye disease, its etiology, diagnostic methods, and current therapeutic options.

Effectiveness of Combined Tear Film Therapy in Patients with Evaporative Dry Eye with Short Tear Film Breakup Time

2017 ◽  
Vol 33 (8) ◽  
pp. 635-643 ◽  
Author(s):  
Yung Hui Kim ◽  
Yeon Soo Kang ◽  
Hyo Seok Lee ◽  
Won Choi ◽  
In Cheon You ◽  
...  
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Evaporative Dry Eye ◽  
Breakup Time

scholarly journals Comparative of meibomian gland morphology in patients with evaporative dry eye disease versus non-dry eye disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ricaurte Ramiro Crespo-Treviño ◽  
Anna Karen Salinas-Sánchez ◽  
Francisco Amparo ◽  
Manuel Garza-Leon
Keyword(s):  
Dry Eye ◽  
Healthy Subjects ◽  
Morphological Changes ◽  
Tear Film ◽  
Meibomian Gland ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Ocular Surface Disease Index ◽  
Evaporative Dry Eye ◽  
The Impact

AbstractMany recent studies have showed that morphological changes are one of the key signs of meibomian gland disease (MGD). These changes can be seen even before symptom onset, potentially underestimating the prevalence of MGD; however, until now, there is no conclusive information about the impact of meibomian gland (MG) morphology in tear film physiology and disease. This study aimed to investigate the prevalence of anatomical and morphological MG alterations between patients with evaporative dry eye disease (DED) and healthy controls. Retrospective chart review of seventy-five patients with evaporative DED and healthy individuals who had dry eye assessments included Ocular Surface Disease Index questionnaire, meibum quality, meibum expressibility, lid margin abnormality, ocular staining, non-invasive tear film break-up time, and meibography. We did not find significant differences in MG alterations in the upper lid between healthy and DED subjects. Patients with evaporative DED presented MG alterations in the lower lid more frequently than healthy subjects (54.8 vs. 30.3%; p = 0.03). The presence of shortened glands was the only MG alteration that was more prevalent in the lower lid in dry-eye patients than in healthy subjects (p < 0.05). Subjects with evaporative DED presented more alterations in the lower lid than healthy subjects.

scholarly journals MON-704 Tear Glands and the Diabetic Patient: Is It a Biomarker?

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Donia Momen ◽  
Gloria Wu ◽  
Shannon Luu ◽  
Brian Leung
Keyword(s):  
Dry Eye ◽  
Infrared Imaging ◽  
Tear Film ◽  
Diabetic Patients ◽  
Test Results ◽  
Inclusion Criteria ◽  
Corneal Surgery ◽  
Percentage Loss ◽  
Meibomian Glands ◽  
Lab Test

Abstract Background: Tear glands in the eyelids, meibomian glands, play a role in tear film production and tear film stabilization. Diabetic patients often complain of dry eye and eye pain. Recently, there are new infrared (820nm) photography techniques to image meibomian glands easily in patients. Purpose: To study meibomian glands in diabetic patients with dry eye. Methods: A retrospective chart review (2017-2019) of Type 2 Diabetes Mellitus (T2DM) patients and non-diabetic patients with the diagnosis of “dry eye” in EHR (eClinicalworks, Westborough, MA) was performed. Infrared eyelid imaging (820 nm wavelength, Heidelberg Spectralis, Heidelberg, Germany) was taken. T2DM: Inclusion criteria: 1) HbA1c of &gt; 5.7% who also had infrared eyelid imaging performed + 4 weeks of their HbA1c lab test results; 2) the percentage loss of meibomian glands for each eye, then averaged, for each patient. Control: Inclusion criteria: 1) non-diabetic patients; 2) HbA1c lab test results; 3) infrared eyelid imaging was performed; 4) percentage loss of meibomian glands was calculated for each eye, then averaged per patient. Exclusion criteria for both T2DM and Controls: younger than the age of 18 years old, older than 90 years old, no glaucoma topical medications, no eyelid surgery, no corneal surgery, no conjunctival surgery. Results: n=120 patients, Avg Age=69.6 years (sd=15.1, range 23-89 years). Diabetic patients: n=60 patients, Male=30, Female=30, Avg Age=65.1 years (sd=11.50, med=65.5, range 36-85 years). Controls: n=60 patients, Male=37, Female=23, Avg Age=54.1 years (sd=16.4, med=56.5, range 23-89 years). Meibomian gland loss: Diabetics=51.54%, Controls=11.29% (p&lt;0.0001, t-test). Of the 60 DM patients: 35/37pts with HbA1c &gt; 6.6% had greater loss of meibomian glands (&gt;40%), compared to 12/23 DM patients with HbA1c &lt; 6.5%, p=0.0001. Discussion: Loss of meibomian glands in diabetic patients have been recently investigated; however, its relationship to HbA1c as a possible biomarker has not been widely discussed in literature. In this small study, loss of meibomian glands occur more frequently with elevated HbA1c, perhaps due to microischemia of the eyelids, thereby resulting in loss of meibomian glands. Conclusion: Loss of meibomian glands may suggest a need for HbA1c testing and further monitoring of the patient’s diabetic condition. Infrared imaging of the eyelid may be useful in characterizing dry eye in diabetic patients.

scholarly journals Comparative of Meibomian Gland Morphology in Patients With Evaporative Dry Eye Versus Non-Dry Eye

2021 ◽  
Author(s):  
Ricaurte Ramiro Crespo-Treviño ◽  
Anna Karen Salinas-Sánchez ◽  
Francisco Amparo ◽  
Manuel Garza-Leon
Keyword(s):  
Dry Eye ◽  
Healthy Subjects ◽  
Morphological Changes ◽  
Tear Film ◽  
Retrospective Chart Review ◽  
Meibomian Gland ◽  
Ocular Surface Disease Index ◽  
Non Invasive ◽  
Evaporative Dry Eye ◽  
The Impact

Abstract Many recent studies have demonstrated that morphological changes are one of the key signs of Meibomian gland disease (MGD) . These changes can be seen even before symptom onset, potentially underestimating the prevalence of MGD; however, Until now, there is no conclusive information about the impact of MG morphology in tear film physiology and disease. This study aimed to investigate the prevalence of anatomical and morphological MG alterations between patients with evapo-rative DED and healthy controls. Retrospective chart review of Seventy-five patients with evaporative dry eye and healthy individuals who had dry eye assesments included Ocular Surface Disease Index questionnaire, Meibum quality, meibum expressibility, lid margin abnormality, ocular staining, non-invasive tear film break-up time, and Meibography. We did not find significant differences in MG alterations in the upper lid between healthy and dry-eye subjects. Patients with evaporative dry eye presented MG alterations in the lower lid more frequently than healthy subjects (54.8 vs 30.3%; p=0.03). The presence of shortened glands was the only MG alteration that was more prevalent in the lower lid in dry-eye patients than in healthy subjects (p <0.05). Subjects with evaporative dry eye presented more alterations in the lower lid than healthy subjects.

scholarly journals Dry Eye Syndrome in Glaucomatous Patients using Topical Anti-Glaucoma Therapy

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Nabila Zulfiqar ◽  
Muhammad Sufyan Aneeq Ansari ◽  
Khurram Nafees ◽  
Rabia Nawaz ◽  
Manzra Shaheen
Keyword(s):  
Observational Study ◽  
Study Design ◽  
Dry Eye ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Film Stability ◽  
Glaucoma Therapy ◽  
Tear Film Stability ◽  
Time Test ◽  
Break Up

Purpose:  To determine the frequency of Dry eye in Glaucoma patients using topical anti-glaucoma therapy. Study Design:  Descriptive Observational study. Place and Duration of Study:  Study was conducted in outpatient department of Fatima Memorial Hospital Shadman, Lahore, from October 2016 to February 2017. Material & Methods:  In this study, 61 diagnosed cases of glaucoma were included. Patients with significant dermatological problems that may be associated with dry eye such as rosacea and blepharitis were excluded from the study. The individuals were assessed by consultant Ophthalmologist for Dry eye syndrome having symptoms of stinging and burning sensations itching, watering, irritation, due to regular use of topical anti-glaucoma drugs. A written consent was taken from every patient before the test. The ocular surfaces of the patients were evaluated using Tear film break-up time test and Basal Schrimer’s test. Patients having TBUT less than 11 seconds were categorized as having dry eye. The degree of dryness was categorized as mild, moderate and sever Dry eye. Results:  Among 61 patients of glaucoma using topical anti-glaucoma therapy, 22 (36.1%) were male and 39 (63.9%) were female. Mean age of the patients was 50.76 ± 15.67 years. On the basis of Tear film Break-up time test, 49 (81%) patients had Tear Break-up time less than 10 seconds and 12 (19%) patients were normal. On the basis of Schrimer`s test 51 (83.66%) patients had Dry eye. Conclusion:  Topical use of anti-glaucoma therapy affects tear film stability and its functions leading to Dry eye syndrome.

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