scholarly journals Prolonged Sinus Pauses upon Termination of Paroxysmal Atrial Fibrillation: Abnormal Right Atrial Electrophysiologic and Electroanatomic Findings

2017 ◽  
Vol 44 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Zhengyu Bao ◽  
Hongwu Chen ◽  
Bing Yang ◽  
Michael Shehata ◽  
Weizhu Ju ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Sinus Node ◽  
P Wave ◽  
Right Atrial ◽  
Control Group ◽  
Paroxysmal Supraventricular Tachycardia ◽  
Group A ◽  
Group B ◽  
Activation Times ◽  
The Right

The efficacy of pulmonary vein antral isolation for patients with prolonged sinus pauses (PSP) on termination of atrial fibrillation has been reported. We studied the right atrial (RA) electrophysiologic and electroanatomic characteristics in such patients. Forty patients underwent electroanatomic mapping of the RA: 13 had PSP (group A), 13 had no PSP (group B), and 14 had paroxysmal supraventricular tachycardia (control group C). Group A had longer P-wave durations in lead II than did groups B and C (115.5 ± 15.4 vs 99.5 ± 10.9 vs 96.5 ± 10.4 ms; P=0.001), and RA activation times (106.8 ± 13.8 vs 99 ± 8.7 vs 94.5 ± 9.1 s; P=0.02). Group A's PP intervals were longer during adenosine triphosphate testing before ablation (4.6 ± 2.3 vs 1.7 ± 0.6 vs 1.5 ± 1 s; P <0.001) and after ablation (4.7 ± 2.5 vs 2.2 ± 1.4 vs 1.6 ± 0.8 s; P <0.001), and group A had more complex electrograms (11.4% ± 5.4% vs 9.3% ± 1.6% vs 5.8% ± 1.6%; P <0.001). Compared with group C, group A had significantly longer corrected sinus node recovery times at a 400-ms pacing cycle length after ablation, larger RA volumes (100.1 ± 23.1 vs 83 ± 22.1 mL; P=0.04), and lower conduction velocities in the high posterior (0.87 ± 0.13 vs 1.02 ± 0.21 mm/ms; P=0.02) and high lateral RA (0.89 ± 0.2 vs 1.1 ± 0.35 mm/ms; P=0.04). We found that patients with PSP upon termination of atrial fibrillation have RA electrophysiologic and electroanatomic abnormalities that warrant post-ablation monitoring.

Prognostic Factors for Late Ventricular Arrhythmias after Repair of Tetralogy of Fallot

1997 ◽  
Vol 5 (1) ◽  
pp. 20-24
Author(s):  
Fumikazu Nomura ◽  
Seiichiro Ikawa ◽  
Keishi Kadoba ◽  
Masataka Mitsuno ◽  
Yoshiki Sawa ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Right Ventricular ◽  
Tetralogy Of Fallot ◽  
Ventricular Arrhythmias ◽  
Right Atrial ◽  
Age At Surgery ◽  
Group A ◽  
Group B ◽  
The Right

During a median follow-up period of 9 years (ranging from 9 months to 25 years), 24-hour ambulatory electrocardiographic studies were undertaken in 155 patients after repair of tetralogy of Fallot. The patients were divided into two groups. Group A consisted of 76 patients in whom the right ventricular approach was used and group B comprised 79 patients whose repair was through the right atrium. A transannular patch was employed in all patients in group A and in none of the patients in group B. Age at surgery was between 1 and 37 years (median age 4.8 years). During follow-up, 37 patients (48.6%) in group A had significant ventricular arrhythmias (Lown grade 2 or higher) and 13 patients (15.4%) in group B had significant ventricular arrhythmias. A close relationship was observed between age at surgery and Lown grade (R2 = 0.374, p < 0.001) and between follow-up duration and Lown grade (R2 = 0.514, p < 0.001), especially when the two groups were analyzed separately (R2 = 0.502, 0.476, p < 0.001). In contrast, no significant relationship was observed between the ratio of right ventricular to left ventricular pressure and Lown grade or between right ventricular systolic pressure and Lown grade. Discriminant analysis revealed risk factors associated with postoperative ventricular arrhythmias are follow-up duration (partial F = 3.22, p < 0.01), right ventricular to pulmonary artery pressure gradient (partial F = 3.35, p < 0.01), and operative method (partial F = 2.4, p < 0.05). Despite antiarrhythmic therapy, 11 of 22 late postoperative deaths occurred suddenly, presumably from ventricular arrhythmias. In this series of patients, the right atrial and pulmonary artery approach significantly reduced the risk of life-threatening ventricular arrhythmias after repair of tetralogy of Fallot.

Histologic Evaluation of Stapled Right Atrial Appendages with Fabric Buttressing

2010 ◽  
Vol 5 (5) ◽  
pp. 359-363
Author(s):  
Hideyuki Fumoto ◽  
A. Marc Gillinov ◽  
D. Geoffrey Vince ◽  
Masatoshi Akiyama ◽  
Diyar Saeed ◽  
...  
Keyword(s):  
Doppler Echocardiography ◽  
Fibrous Tissue ◽  
Atrial Appendage ◽  
Right Atrial ◽  
Histologic Evaluation ◽  
Group A ◽  
Right Atrial Appendage ◽  
Group B ◽  
The Right ◽  
Group D

Objective The aim of this study was to histologically evaluate the importance of using buttressing materials in stapling the atrial appendages. Methods We stapled the right atrial appendage with a commercial apparatus in 11 mongrel dogs. To evaluate the efficiency of using a buttressing material as an adjunct to stapling, we conducted 30-day studies without (group A: n = 2) or with buttressing material (group B: n = 3) and 90-day studies without (group C: n = 3) or with buttressing material (group D: n = 3) and thereafter made assessments using Doppler echocardiography and performed histologic analyses on all stapled appendages. Results During surgery, blood oozing from the stapling sites was observed in four of five cases of groups A and C; with buttressing, there was no oozing in groups B and D. In groups A and B, we observed the myocardium of the appendage being focally replaced with fibrous tissue. Myocardium in group C was infiltrated diffusely with loose fibrous tissue and in group D had been almost completely replaced with fibrous tissue. Conclusions The buttressing material was useful not only in preventing oozing but also likely promoting the growth of fibrous tissue in the right atrial appendage.

scholarly journals 123 PROGESTERONE LEVELS DURING 20 DAYS OF PREGNANCY IN RABBIT TREATED FOR ENDOMETRIOSIS OR WITH ANTI-CD44

2005 ◽  
Vol 17 (2) ◽  
pp. 212
Author(s):  
M.J. Illera ◽  
P. Bermejo ◽  
A. Natarajan ◽  
C. Willingham ◽  
J. Hernandez
Keyword(s):  
Embryo Implantation ◽  
Normal Pregnancy ◽  
Uterine Horn ◽  
Control Group ◽  
Corpora Lutea ◽  
Cell Surface Molecule ◽  
Group A ◽  
A Cell ◽  
Group B ◽  
The Right

Embryo implantation begins when the blastocyst both assumes a fixed position in the uterus and establishes a more intimate relationship with the endometrium. Successful implantation depends upon hormonal synchronization and development and the receptivity of the endometrium. CD44 is a cell surface molecule that has been implicated in the initial attachment of the embryo. The aim of this work was to study the hormonal levels of P4 in three groups of animals which have a normal pregnancy or an induced reduction in the number of implants. Twelve adult New Zealand does (n = 12) were naturally inseminated with a buck of proven fertility. Blood samples were obtained daily during 20 days of pregnancy. Hormonal determinations were performed by enzyme immunoassay. Animals were divided into three groups: group A (n = 4): control animals; group B (n = 4): endometriosis was surgically induced in the right horn a month before the animal was mated; and group C (n = 4): animals received an injection of 20 micrograms of anti-CD44 in the right horn via mid-ventral laparotomy on Day 6.5 post-coitum (0.5 mL each, from the ovarian end to the cervix). Each animal served as her own control with the left uterine horn receiving 0.5 mL of saline. Statistical analysis was performed using ANOVA.The number of corpora lutea was similar in all treatments. No statistical differences were found comparing CLs in the right/left ovary. In group A, a mean of 3.4 ± 0.47 (mean ± SE) implants was found in the right horn while the mean in the left side was 4.6 ± 0.81. In group B, a marked reduction in implantation sites was found, with 1.8 ± 0.60 and 4.66 ± 0.84 on the right and left horns, respectively. With anti-CD44 injected into the uterine horn (Group C), a mean of 0.12 implant was present in the right uterine horn compared with 3.6 implants on the left side (P < 0.001). Progesterone levels from Days 1 to 10 are shown in the following table (mean ± SE). Comparisons in day values are not statistically significant P > 0.05. After Day 10 the levels of progesterone were similar in all groups. The results showed an increase of progesterone levels in group B; this could be due to endometriosis and not to the number of implants. The results in the CD44 group reveal that progesterone profiles were similar to those in the control group, and we can conclude that the reduced number of implants found in group C did not affect the progesterone levels. Table 1. Progesterone levels (ng/mL) from Days 1 to 10 (mean ± SE)

Effect of Hemiovariectomy on reproductive performance in Chinchila Rabbits.

2021 ◽  
Vol 36 (1) ◽  
pp. 167-174
Author(s):  
C. A. Eze ◽  
C. P. Nwodo ◽  
E. O. Ogbu
Keyword(s):  
Birth Weight ◽  
Litter Size ◽  
Conception Rate ◽  
Control Group ◽  
Significant Difference ◽  
Negative Effect ◽  
Group A ◽  
Group B ◽  
The Right ◽  
Reproductive Indices

This work evaluates the effects of hemiovariectomi (37 some reproductive indices such as conception rate, birth weight and birth litter size in Chinchilla breed of rabbits. Thirty females and six males were used for the experiment. The males were examined for breeding soundness before using them to cross the females. The experiment was replicated in two batches of three groups of five females and a male each at different periods. Hemi-ovariectomy was carried out in the right ovary of 10 does (Group A) and left ovary of another 10 does (Group B). Ten females in Group C were not ovariectomised and served as the control group. All groups were served at reproductive maturity by rotating the bucks. Pregnancy was diagnosed using a standard method. The reproductive indices evaluated included conception rate, birth weight and birth litter size. Data were analyzed using percentages, ratios, and analysis of variance (ANOVA) was computed where necessary. Results showed that hemi ovariectomy significantly (P<0.01) reduced the mean litter size, Group A (2.50+58), Group B (3.00+0.71), control (Group C) (6.20+0.84). However, there was increased mean litter birth weight which, differed significantly (P<0.01) from that of the control (27.06), Group A (33.64+1.86) and Group B (33.93=1.75). Also, the conception rate in the treated groups averaged 65% while the control was 80%. There was no significant difference (P>0.05) between the groups in the interval from the introduction of the huck to the does to the time of conception. It is concluded thai hemiovariectomy has negative effect on the conception rate and birth litter size but has positive effect on birth litter weight. The procedure has shown that in highly priced breed of animal with unilateral ovarian uilments such an animal can still be used for breeding using the healthy ovary: The procedure could also be a more reliable method of birth control in pet animals as well as a means of producing heavy weight offspring.

scholarly journals Mapping and Preserving the Visuospatial Network by repetitive nTMS and DTI Tractography in Patients With Right Parietal Lobe Tumors

2021 ◽  
Vol 11 ◽  
Author(s):  
Giovanni Raffa ◽  
Maria Catena Quattropani ◽  
Giuseppina Marzano ◽  
Antonello Curcio ◽  
Vincenzo Rizzo ◽  
...  
Keyword(s):  
3D Reconstruction ◽  
Parietal Lobe ◽  
Tumor Resection ◽  
Historical Control ◽  
Control Group ◽  
Cortical Areas ◽  
Group A ◽  
Dti Tractography ◽  
Group B ◽  
The Right

IntroductionThe goal of brain tumor surgery is the maximal resection of neoplastic tissue, while preserving the adjacent functional brain tissues. The identification of functional networks involved in complex brain functions, including visuospatial abilities (VSAs), is usually difficult. We report our preliminary experience using a preoperative planning based on the combination of navigated transcranial magnetic stimulation (nTMS) and DTI tractography to provide the preoperative 3D reconstruction of the visuospatial (VS) cortico-subcortical network in patients with right parietal lobe tumors.Material and MethodsPatients affected by right parietal lobe tumors underwent mapping of both hemispheres using an nTMS-implemented version of the Hooper Visual Organization Test (HVOT) to identify cortical areas involved in the VS network. DTI tractography was used to compute the subcortical component of the network, consisting of the three branches of the superior longitudinal fasciculus (SLF). The 3D reconstruction of the VS network was used to plan and guide the safest surgical approach to resect the tumor and avoid damage to the network. We retrospectively analyzed the cortical distribution of nTMS-induced errors, and assessed the impact of the planning on surgery by analyzing the extent of tumor resection (EOR) and the occurrence of postoperative VSAs deficits in comparison with a matched historical control group of patients operated without using the nTMS-based preoperative reconstruction of the VS network.ResultsTwenty patients were enrolled in the study (Group A). The error rate (ER) induced by nTMS was higher in the right vs. the left hemisphere (p=0.02). In the right hemisphere, the ER was higher in the anterior supramarginal gyrus (aSMG) (1.7%), angular gyrus (1.4%) superior parietal lobule (SPL) (1.3%), and dorsal lateral occipital gyrus (dLoG) (1.2%). The reconstruction of the cortico-subcortical VS network was successfully used to plan and guide tumor resection. A gross total resection (GTR) was achieved in 85% of cases. After surgery no new VSAs deficits were observed and a slightly significant improvement of the HVOT score (p=0.02) was documented. The historical control group (Group B) included 20 patients matched for main clinical characteristics with patients in Group A, operated without the support of the nTMS-based planning. A GTR was achieved in 90% of cases, but the postoperative HVOT score resulted to be worsened as compared to the preoperative period (p=0.03). The comparison between groups showed a significantly improved postoperative HVOT score in Group A vs. Group B (p=0.03).ConclusionsThe nTMS-implemented HVOT is a feasible approach to map cortical areas involved in VSAs. It can be combined with DTI tractography, thus providing a reconstruction of the VS network that could guide neurosurgeons to preserve the VS network during tumor resection, thus reducing the occurrence of postoperative VSAs deficits as compared to standard asleep surgery.

Do trabecular metal and cancellous titanium implants reduce the risk of late haematogenous infection? An experimental study in rabbits

2020 ◽  
pp. 112070002092889
Author(s):  
George Komnos ◽  
Konstantinos Banios ◽  
Konstantina Kolonia ◽  
Lazaros A Poultsides ◽  
Efthimia Petinaki ◽  
...  
Keyword(s):  
Titanium Implants ◽  
Microbial Pathogens ◽  
Control Group ◽  
Trabecular Metal ◽  
Sterile Saline ◽  
Initial Procedure ◽  
Group A ◽  
Group B ◽  
The Right ◽  
Group D

Aim: This study evaluated the late resistance to haematogenous contamination by microbial pathogens of implants and bone-implant interface and the development of late clinical infection when cementless components with different surface or structural properties are implanted. Material and methods: 50 adult male New Zealand white rabbits were divided into 5 groups of 10 animals each. In Group A smooth titanium, in Group B grit blasted titanium, in Group C HA-coated titanium, in Group D trabecular metal and in group E cancellous titanium rods were implanted in the right proximal tibia. Four weeks later, 1 ml of inoculum of a standardised CA-MRSA strain (3 × 108 cfu/ml) was injected through a femoral artery catheter (groups B, C, D, E) while in group A, 1 ml of sterile saline was injected in a similar way (control group). Subjects were killed 8 weeks after the initial procedure and 3 samples of each tibial specimen were subjected to conventional cultures and PCR studies. Results: The number of the specimens (conventional cultures and PCR studies) contaminated by the standardized pathogen was as follows: Group A: 0/10, Group B: 7/10, Group C: 6/10, Group D; 5/10 and Group E: 5/10. Comparing the number of colony form units isolated from the implant samples, Group B (GB titanium) showed statistically significantly higher values (Mann-Whitney test) compared to Group C ( p = 0.044), Group D ( p = 0.040) and Group E ( p = 0.038). Local active infection was observed in 6 animals: 3 in Group B; 1 in Group C, 1 in Group D, and 1 in Group E. Conclusions: Modern cementless implants (trabecular metal and cancellous titanium) showed a lower risk of implant contamination and late clinical haematogenous infection.

Right heart pressures and blood-gas tensions in ponies during exercise and laryngeal hemiplegia

1986 ◽  
Vol 251 (1) ◽  
pp. H121-H126 ◽  
Author(s):  
M. Manohar
Keyword(s):  
Heart Rate ◽  
Pulmonary Artery ◽  
Pleural Pressure ◽  
Right Atrial ◽  
Stride Frequency ◽  
Group A ◽  
Alveolar Hypoxia ◽  
Severe Exercise ◽  
Group B ◽  
The Right

Right atrial, right ventricular, and pulmonary artery pressures, along with change in pleural pressure, were determined with catheter-tipped micromanometers in two groups of ponies at rest, as well as during moderate (trot; heart rate = 180 beats . min-1) and severe (gallop; heart rate = 220 beats . min-1) exercise performed on a treadmill. Group A (n = 8) ponies served as controls, and group B ponies (n = 6) had laryngeal hemiplegia (LH) induced by sectioning the left recurrent laryngeal nerve 20-29 days before the study. It was observed that LH ponies could not gallop for more than 45-90 s. With both levels of exertion, pressures in the right atrium, right ventricle, and pulmonary artery increased very significantly in normal ponies. The change in pleural pressure of galloping ponies was 30.4 +/- 2.9 cmH2O, and the respiratory (and stride) frequency was 138 +/- 4 breaths . min-1. During severe exercise in normal ponies, the systolic, mean, and diastolic pressures in the pulmonary artery were 107 +/- 7, 63.5 +/- 4.2, and 46 +/- 4 mmHg, despite the fact that no alveolar hypoxia could be detected. In LH ponies pulmonary artery pressures rose to levels observed in normal ponies, but during galloping, the change in pleural pressure (delta Ppl) (92 +/- 6 cmH2O) was three times that in normal ponies, and there was no synchronization of respiratory (86 +/- 6 breaths . min-1) frequency to stride frequency (142 +/- 3 strides . min-1). Despite these respiratory adjustments (decreased frequency and increased delta Ppl), arterial PO2 decreased and arterial PCO2 increased in galloping LH ponies.(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals Predictors of Good Metabolic Control of Diabetes in Adolescents Social, Epidemiological and Neuropsychological Dimensions

2021 ◽  
pp. 15-21
Author(s):  
Jihane Ziati ◽  
Najlae El- Hafidi ◽  
Naima Bennani ◽  
Zineb Imane
Keyword(s):  
Metabolic Control ◽  
New Technologies ◽  
Epidemiological Data ◽  
Therapeutic Education ◽  
Control Group ◽  
The Family ◽  
Group A ◽  
Control Of Diabetes ◽  
Group B ◽  
The Right

Our study included 60 children with diabetes. We divided them into two groups: Group A and Group B. Patients assigned to Group A had controlled diabetes and formed our “Control Group”, while Group B was for patients with poorly controlled diabetes. This study was conducted in « The Home of the Young Diabetic » center in collaboration with the diabetes unit at the pediatric hospital of Rabat. Our goal was to identify the different predictors of metabolic control in diabetic adolescents by looking at the epidemiological data, lifestyle, social level, and the family life of different categories. Finally, we analyzed the results and suggested solutions. To improve the medical care of diabetes provide better control of the teenage period and reinforce therapeutic education, it is necessary to propose social help to families in need and expand the right of health insurance to all citizens but also refund all the new technologies in diabetes treatment. Lastly, we suggested the integration of a psychological test at the beginning of the diabetes discovery and add it to the screening of complications.

scholarly journals Selective hypothermia: an experimental study on traumatic brain injury in rats

2008 ◽  
Vol 66 (2b) ◽  
pp. 391-396 ◽  
Author(s):  
Amylcar Edemilson Dvilevicius ◽  
Mirto Nelso Prandini
Keyword(s):  
Traumatic Brain Injury ◽  
Experimental Study ◽  
Brain Injury ◽  
Control Group ◽  
Histopathological Analysis ◽  
Group A ◽  
Cortical Impact ◽  
The Difference ◽  
Group B ◽  
The Right

OBJECTIVE: To evaluate the efficiency of selective hypothermia in the treatment of the traumatic brain injury in rats. METHOD: After the trauma produced for the model of cortical impact, a small craniectomy in the right frontoparietal region was carried through; after the procedure the animals had been divided in two groups of 15 each. Group A, without treatment with hypothermia (control group) and group B, treated with selective hypothermia for a period to 5 to 6 hours. After this time all the animals were sacrificed, their brains had been removed and histopathological analysis was carried through. RESULTS: Comparison between both groups was done using the counting of neurons injured for field. Counting in the control group n=15 had an average of 70.80 neurons injured for field against an average of 21.33 neurons injured for field in group B (submitted to the treatment with hypothermia), with n=15 also. The difference was statiscally significant. CONCLUSION: Based in the quantification of the neurons injured for field, the effectiveness of the treatment with selective hypothermia was demonstrated.

scholarly journals Efektifitas latihan nebraska agility drill dan shuttle run untuk meningkatkan kelincahan dribble dalam permainan sepakbola pada Ssb Putra Rayung Kususma

2021 ◽  
Vol 2 (2) ◽  
pp. 195-203
Author(s):  
Dwicky Nurma Hendra Data
Keyword(s):  
Test Group ◽  
Control Group ◽  
Training Methods ◽  
Average Difference ◽  
Post Test ◽  
Group A ◽  
Group B ◽  
The Right ◽  
Shuttle Run ◽  
Better Than

Footballers at SSB Putra Rayung Kusuma tend to make mistakes when dribbling the ball that is not maximal in training and mini-game conditions, the athlete is not placed in the right position, he should be placed with the athlete's ability, because the coach only obeys the athlete's wishes for positioning. Therefore, the researcher intends to analyze the Nebraska Agility Drill and shuttle run on SSB footballer Putra Rayung Kusuma to find out the footballer's talent. The research method used by the author is experimental. The characteristic in this design is the presence of a control group. The type of data used in this study is premier data. The premiere data in this study were obtained directly from observations at SSB Putra Rayung Kusuma. Based on the results of the t-test, it shows that there is no difference between the two training methods, with t count 0.49> t table 1.73 with a significance value p of 0.67> 0.05, this result shows that there is no difference between the post-test group A and group B. Based on the results of the analysis shows that the increase in the percentage of group A is better than group B, and the average post-test for group A is 17.00 and group B is 17.20 with an average difference of 0.20. Thus the hypothesis which reads "The Nebraska Agility Drill training method is more effective for increasing dribble agility in soccer for athletes aged 12-14 years than shuttle run training", Thus, it can be concluded that the Nebraska Agility Drill Method is more effective for increasing dribble agility in football for athletes aged 12-14 years than shuttle run training with an average difference of 0.20.

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