scholarly journals Predictors of Good Metabolic Control of Diabetes in Adolescents Social, Epidemiological and Neuropsychological Dimensions

2021 ◽  
pp. 15-21
Author(s):  
Jihane Ziati ◽  
Najlae El- Hafidi ◽  
Naima Bennani ◽  
Zineb Imane
Keyword(s):  
Metabolic Control ◽  
New Technologies ◽  
Epidemiological Data ◽  
Therapeutic Education ◽  
Control Group ◽  
The Family ◽  
Group A ◽  
Control Of Diabetes ◽  
Group B ◽  
The Right

Our study included 60 children with diabetes. We divided them into two groups: Group A and Group B. Patients assigned to Group A had controlled diabetes and formed our “Control Group”, while Group B was for patients with poorly controlled diabetes. This study was conducted in « The Home of the Young Diabetic » center in collaboration with the diabetes unit at the pediatric hospital of Rabat. Our goal was to identify the different predictors of metabolic control in diabetic adolescents by looking at the epidemiological data, lifestyle, social level, and the family life of different categories. Finally, we analyzed the results and suggested solutions. To improve the medical care of diabetes provide better control of the teenage period and reinforce therapeutic education, it is necessary to propose social help to families in need and expand the right of health insurance to all citizens but also refund all the new technologies in diabetes treatment. Lastly, we suggested the integration of a psychological test at the beginning of the diabetes discovery and add it to the screening of complications.

scholarly journals Prolonged Sinus Pauses upon Termination of Paroxysmal Atrial Fibrillation: Abnormal Right Atrial Electrophysiologic and Electroanatomic Findings

2017 ◽  
Vol 44 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Zhengyu Bao ◽  
Hongwu Chen ◽  
Bing Yang ◽  
Michael Shehata ◽  
Weizhu Ju ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Sinus Node ◽  
P Wave ◽  
Right Atrial ◽  
Control Group ◽  
Paroxysmal Supraventricular Tachycardia ◽  
Group A ◽  
Group B ◽  
Activation Times ◽  
The Right

The efficacy of pulmonary vein antral isolation for patients with prolonged sinus pauses (PSP) on termination of atrial fibrillation has been reported. We studied the right atrial (RA) electrophysiologic and electroanatomic characteristics in such patients. Forty patients underwent electroanatomic mapping of the RA: 13 had PSP (group A), 13 had no PSP (group B), and 14 had paroxysmal supraventricular tachycardia (control group C). Group A had longer P-wave durations in lead II than did groups B and C (115.5 ± 15.4 vs 99.5 ± 10.9 vs 96.5 ± 10.4 ms; P=0.001), and RA activation times (106.8 ± 13.8 vs 99 ± 8.7 vs 94.5 ± 9.1 s; P=0.02). Group A's PP intervals were longer during adenosine triphosphate testing before ablation (4.6 ± 2.3 vs 1.7 ± 0.6 vs 1.5 ± 1 s; P <0.001) and after ablation (4.7 ± 2.5 vs 2.2 ± 1.4 vs 1.6 ± 0.8 s; P <0.001), and group A had more complex electrograms (11.4% ± 5.4% vs 9.3% ± 1.6% vs 5.8% ± 1.6%; P <0.001). Compared with group C, group A had significantly longer corrected sinus node recovery times at a 400-ms pacing cycle length after ablation, larger RA volumes (100.1 ± 23.1 vs 83 ± 22.1 mL; P=0.04), and lower conduction velocities in the high posterior (0.87 ± 0.13 vs 1.02 ± 0.21 mm/ms; P=0.02) and high lateral RA (0.89 ± 0.2 vs 1.1 ± 0.35 mm/ms; P=0.04). We found that patients with PSP upon termination of atrial fibrillation have RA electrophysiologic and electroanatomic abnormalities that warrant post-ablation monitoring.

scholarly journals 123 PROGESTERONE LEVELS DURING 20 DAYS OF PREGNANCY IN RABBIT TREATED FOR ENDOMETRIOSIS OR WITH ANTI-CD44

2005 ◽  
Vol 17 (2) ◽  
pp. 212
Author(s):  
M.J. Illera ◽  
P. Bermejo ◽  
A. Natarajan ◽  
C. Willingham ◽  
J. Hernandez
Keyword(s):  
Embryo Implantation ◽  
Normal Pregnancy ◽  
Uterine Horn ◽  
Control Group ◽  
Corpora Lutea ◽  
Cell Surface Molecule ◽  
Group A ◽  
A Cell ◽  
Group B ◽  
The Right

Embryo implantation begins when the blastocyst both assumes a fixed position in the uterus and establishes a more intimate relationship with the endometrium. Successful implantation depends upon hormonal synchronization and development and the receptivity of the endometrium. CD44 is a cell surface molecule that has been implicated in the initial attachment of the embryo. The aim of this work was to study the hormonal levels of P4 in three groups of animals which have a normal pregnancy or an induced reduction in the number of implants. Twelve adult New Zealand does (n = 12) were naturally inseminated with a buck of proven fertility. Blood samples were obtained daily during 20 days of pregnancy. Hormonal determinations were performed by enzyme immunoassay. Animals were divided into three groups: group A (n = 4): control animals; group B (n = 4): endometriosis was surgically induced in the right horn a month before the animal was mated; and group C (n = 4): animals received an injection of 20 micrograms of anti-CD44 in the right horn via mid-ventral laparotomy on Day 6.5 post-coitum (0.5 mL each, from the ovarian end to the cervix). Each animal served as her own control with the left uterine horn receiving 0.5 mL of saline. Statistical analysis was performed using ANOVA.The number of corpora lutea was similar in all treatments. No statistical differences were found comparing CLs in the right/left ovary. In group A, a mean of 3.4 ± 0.47 (mean ± SE) implants was found in the right horn while the mean in the left side was 4.6 ± 0.81. In group B, a marked reduction in implantation sites was found, with 1.8 ± 0.60 and 4.66 ± 0.84 on the right and left horns, respectively. With anti-CD44 injected into the uterine horn (Group C), a mean of 0.12 implant was present in the right uterine horn compared with 3.6 implants on the left side (P < 0.001). Progesterone levels from Days 1 to 10 are shown in the following table (mean ± SE). Comparisons in day values are not statistically significant P > 0.05. After Day 10 the levels of progesterone were similar in all groups. The results showed an increase of progesterone levels in group B; this could be due to endometriosis and not to the number of implants. The results in the CD44 group reveal that progesterone profiles were similar to those in the control group, and we can conclude that the reduced number of implants found in group C did not affect the progesterone levels. Table 1. Progesterone levels (ng/mL) from Days 1 to 10 (mean ± SE)

Effect of Hemiovariectomy on reproductive performance in Chinchila Rabbits.

2021 ◽  
Vol 36 (1) ◽  
pp. 167-174
Author(s):  
C. A. Eze ◽  
C. P. Nwodo ◽  
E. O. Ogbu
Keyword(s):  
Birth Weight ◽  
Litter Size ◽  
Conception Rate ◽  
Control Group ◽  
Significant Difference ◽  
Negative Effect ◽  
Group A ◽  
Group B ◽  
The Right ◽  
Reproductive Indices

This work evaluates the effects of hemiovariectomi (37 some reproductive indices such as conception rate, birth weight and birth litter size in Chinchilla breed of rabbits. Thirty females and six males were used for the experiment. The males were examined for breeding soundness before using them to cross the females. The experiment was replicated in two batches of three groups of five females and a male each at different periods. Hemi-ovariectomy was carried out in the right ovary of 10 does (Group A) and left ovary of another 10 does (Group B). Ten females in Group C were not ovariectomised and served as the control group. All groups were served at reproductive maturity by rotating the bucks. Pregnancy was diagnosed using a standard method. The reproductive indices evaluated included conception rate, birth weight and birth litter size. Data were analyzed using percentages, ratios, and analysis of variance (ANOVA) was computed where necessary. Results showed that hemi ovariectomy significantly (P<0.01) reduced the mean litter size, Group A (2.50+58), Group B (3.00+0.71), control (Group C) (6.20+0.84). However, there was increased mean litter birth weight which, differed significantly (P<0.01) from that of the control (27.06), Group A (33.64+1.86) and Group B (33.93=1.75). Also, the conception rate in the treated groups averaged 65% while the control was 80%. There was no significant difference (P>0.05) between the groups in the interval from the introduction of the huck to the does to the time of conception. It is concluded thai hemiovariectomy has negative effect on the conception rate and birth litter size but has positive effect on birth litter weight. The procedure has shown that in highly priced breed of animal with unilateral ovarian uilments such an animal can still be used for breeding using the healthy ovary: The procedure could also be a more reliable method of birth control in pet animals as well as a means of producing heavy weight offspring.

scholarly journals Mapping and Preserving the Visuospatial Network by repetitive nTMS and DTI Tractography in Patients With Right Parietal Lobe Tumors

2021 ◽  
Vol 11 ◽  
Author(s):  
Giovanni Raffa ◽  
Maria Catena Quattropani ◽  
Giuseppina Marzano ◽  
Antonello Curcio ◽  
Vincenzo Rizzo ◽  
...  
Keyword(s):  
3D Reconstruction ◽  
Parietal Lobe ◽  
Tumor Resection ◽  
Historical Control ◽  
Control Group ◽  
Cortical Areas ◽  
Group A ◽  
Dti Tractography ◽  
Group B ◽  
The Right

IntroductionThe goal of brain tumor surgery is the maximal resection of neoplastic tissue, while preserving the adjacent functional brain tissues. The identification of functional networks involved in complex brain functions, including visuospatial abilities (VSAs), is usually difficult. We report our preliminary experience using a preoperative planning based on the combination of navigated transcranial magnetic stimulation (nTMS) and DTI tractography to provide the preoperative 3D reconstruction of the visuospatial (VS) cortico-subcortical network in patients with right parietal lobe tumors.Material and MethodsPatients affected by right parietal lobe tumors underwent mapping of both hemispheres using an nTMS-implemented version of the Hooper Visual Organization Test (HVOT) to identify cortical areas involved in the VS network. DTI tractography was used to compute the subcortical component of the network, consisting of the three branches of the superior longitudinal fasciculus (SLF). The 3D reconstruction of the VS network was used to plan and guide the safest surgical approach to resect the tumor and avoid damage to the network. We retrospectively analyzed the cortical distribution of nTMS-induced errors, and assessed the impact of the planning on surgery by analyzing the extent of tumor resection (EOR) and the occurrence of postoperative VSAs deficits in comparison with a matched historical control group of patients operated without using the nTMS-based preoperative reconstruction of the VS network.ResultsTwenty patients were enrolled in the study (Group A). The error rate (ER) induced by nTMS was higher in the right vs. the left hemisphere (p=0.02). In the right hemisphere, the ER was higher in the anterior supramarginal gyrus (aSMG) (1.7%), angular gyrus (1.4%) superior parietal lobule (SPL) (1.3%), and dorsal lateral occipital gyrus (dLoG) (1.2%). The reconstruction of the cortico-subcortical VS network was successfully used to plan and guide tumor resection. A gross total resection (GTR) was achieved in 85% of cases. After surgery no new VSAs deficits were observed and a slightly significant improvement of the HVOT score (p=0.02) was documented. The historical control group (Group B) included 20 patients matched for main clinical characteristics with patients in Group A, operated without the support of the nTMS-based planning. A GTR was achieved in 90% of cases, but the postoperative HVOT score resulted to be worsened as compared to the preoperative period (p=0.03). The comparison between groups showed a significantly improved postoperative HVOT score in Group A vs. Group B (p=0.03).ConclusionsThe nTMS-implemented HVOT is a feasible approach to map cortical areas involved in VSAs. It can be combined with DTI tractography, thus providing a reconstruction of the VS network that could guide neurosurgeons to preserve the VS network during tumor resection, thus reducing the occurrence of postoperative VSAs deficits as compared to standard asleep surgery.

scholarly journals Effect of epidural analgesia on the duration of labour and pains: a comparative study

2020 ◽  
Vol 9 (4) ◽  
pp. 1451
Author(s):  
Pallavi Chauhan ◽  
S. D. Shirodkar
Keyword(s):  
Pain Relief ◽  
Epidural Analgesia ◽  
New Technologies ◽  
Active Phase ◽  
The Body ◽  
Control Group ◽  
Second Stage Of Labour ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Epidural analgesia is regional anaesthesia that blocks pain in a particular region of the body. The use of Epidural Analgesia (EA) in labor is widespread in modern labor ward practice, and its benefits in terms of pain relief are well-recognized. Objective of this study was to study the effect of epidural analgesia on the duration of labour and pains.Methods: The present study was conducted on 60 women in the department of obstetrics and gynecology at Topiwala National Medical College, Mumbai during a period from October 2014 to January 2017. The women requesting EA were assigned as the study group (Group A - 30 cases) and women not receiving EA were included in the control group (Group B - 30 cases).Results: The duration of active phase of first and second stage of labour was found to be prolonged in patients who received EA as compared to control group. An increase in number of caesarean sections and requirement of oxytocin augmentation was found to be more in Group A as compared to Group B. There was no statistically significant difference in Apgar score of newborns at 1 min and 5 min in both the groups. The patients demanding epidural drug had better pain relief during labour. In Group A, 17% of patients and in Group B, 7% of patients had nausea and vomiting. Other side effects were minimal.Conclusions: Epidural analgesia is not a totally free of disadvantages, it is the most effective mode of pain relief available compared with other techniques. The addition of patient-controlled epidural analgesia and innovations using new technologies enhance patient satisfaction.

Do trabecular metal and cancellous titanium implants reduce the risk of late haematogenous infection? An experimental study in rabbits

2020 ◽  
pp. 112070002092889
Author(s):  
George Komnos ◽  
Konstantinos Banios ◽  
Konstantina Kolonia ◽  
Lazaros A Poultsides ◽  
Efthimia Petinaki ◽  
...  
Keyword(s):  
Titanium Implants ◽  
Microbial Pathogens ◽  
Control Group ◽  
Trabecular Metal ◽  
Sterile Saline ◽  
Initial Procedure ◽  
Group A ◽  
Group B ◽  
The Right ◽  
Group D

Aim: This study evaluated the late resistance to haematogenous contamination by microbial pathogens of implants and bone-implant interface and the development of late clinical infection when cementless components with different surface or structural properties are implanted. Material and methods: 50 adult male New Zealand white rabbits were divided into 5 groups of 10 animals each. In Group A smooth titanium, in Group B grit blasted titanium, in Group C HA-coated titanium, in Group D trabecular metal and in group E cancellous titanium rods were implanted in the right proximal tibia. Four weeks later, 1 ml of inoculum of a standardised CA-MRSA strain (3 × 108 cfu/ml) was injected through a femoral artery catheter (groups B, C, D, E) while in group A, 1 ml of sterile saline was injected in a similar way (control group). Subjects were killed 8 weeks after the initial procedure and 3 samples of each tibial specimen were subjected to conventional cultures and PCR studies. Results: The number of the specimens (conventional cultures and PCR studies) contaminated by the standardized pathogen was as follows: Group A: 0/10, Group B: 7/10, Group C: 6/10, Group D; 5/10 and Group E: 5/10. Comparing the number of colony form units isolated from the implant samples, Group B (GB titanium) showed statistically significantly higher values (Mann-Whitney test) compared to Group C ( p = 0.044), Group D ( p = 0.040) and Group E ( p = 0.038). Local active infection was observed in 6 animals: 3 in Group B; 1 in Group C, 1 in Group D, and 1 in Group E. Conclusions: Modern cementless implants (trabecular metal and cancellous titanium) showed a lower risk of implant contamination and late clinical haematogenous infection.

scholarly journals Selective hypothermia: an experimental study on traumatic brain injury in rats

2008 ◽  
Vol 66 (2b) ◽  
pp. 391-396 ◽  
Author(s):  
Amylcar Edemilson Dvilevicius ◽  
Mirto Nelso Prandini
Keyword(s):  
Traumatic Brain Injury ◽  
Experimental Study ◽  
Brain Injury ◽  
Control Group ◽  
Histopathological Analysis ◽  
Group A ◽  
Cortical Impact ◽  
The Difference ◽  
Group B ◽  
The Right

OBJECTIVE: To evaluate the efficiency of selective hypothermia in the treatment of the traumatic brain injury in rats. METHOD: After the trauma produced for the model of cortical impact, a small craniectomy in the right frontoparietal region was carried through; after the procedure the animals had been divided in two groups of 15 each. Group A, without treatment with hypothermia (control group) and group B, treated with selective hypothermia for a period to 5 to 6 hours. After this time all the animals were sacrificed, their brains had been removed and histopathological analysis was carried through. RESULTS: Comparison between both groups was done using the counting of neurons injured for field. Counting in the control group n=15 had an average of 70.80 neurons injured for field against an average of 21.33 neurons injured for field in group B (submitted to the treatment with hypothermia), with n=15 also. The difference was statiscally significant. CONCLUSION: Based in the quantification of the neurons injured for field, the effectiveness of the treatment with selective hypothermia was demonstrated.

scholarly journals Efektifitas latihan nebraska agility drill dan shuttle run untuk meningkatkan kelincahan dribble dalam permainan sepakbola pada Ssb Putra Rayung Kususma

2021 ◽  
Vol 2 (2) ◽  
pp. 195-203
Author(s):  
Dwicky Nurma Hendra Data
Keyword(s):  
Test Group ◽  
Control Group ◽  
Training Methods ◽  
Average Difference ◽  
Post Test ◽  
Group A ◽  
Group B ◽  
The Right ◽  
Shuttle Run ◽  
Better Than

Footballers at SSB Putra Rayung Kusuma tend to make mistakes when dribbling the ball that is not maximal in training and mini-game conditions, the athlete is not placed in the right position, he should be placed with the athlete's ability, because the coach only obeys the athlete's wishes for positioning. Therefore, the researcher intends to analyze the Nebraska Agility Drill and shuttle run on SSB footballer Putra Rayung Kusuma to find out the footballer's talent. The research method used by the author is experimental. The characteristic in this design is the presence of a control group. The type of data used in this study is premier data. The premiere data in this study were obtained directly from observations at SSB Putra Rayung Kusuma. Based on the results of the t-test, it shows that there is no difference between the two training methods, with t count 0.49> t table 1.73 with a significance value p of 0.67> 0.05, this result shows that there is no difference between the post-test group A and group B. Based on the results of the analysis shows that the increase in the percentage of group A is better than group B, and the average post-test for group A is 17.00 and group B is 17.20 with an average difference of 0.20. Thus the hypothesis which reads "The Nebraska Agility Drill training method is more effective for increasing dribble agility in soccer for athletes aged 12-14 years than shuttle run training", Thus, it can be concluded that the Nebraska Agility Drill Method is more effective for increasing dribble agility in football for athletes aged 12-14 years than shuttle run training with an average difference of 0.20.

scholarly journals 137THE EFFECT OF ANTI-CD44 ON EMBRYO IMPLANTATION IN RABBITS

2004 ◽  
Vol 16 (2) ◽  
pp. 190 ◽  
Author(s):  
M.J. Illera ◽  
P. Bermejo ◽  
J. Hernandez ◽  
A. Gonzalez ◽  
J.C. Illera
Keyword(s):  
Cell Surface ◽  
Intraperitoneal Injection ◽  
Embryo Implantation ◽  
Cellular Adhesion ◽  
Uterine Horn ◽  
Cell Surface Receptor ◽  
Control Group ◽  
Group A ◽  
Group B ◽  
The Right

Cellular adhesion molecules are thought to be responsible in embryo attachment in human and animals. Blastocyst attachment to the lining of the mammalian uterus during early implantation involves the initial apposition of the trophoblast to the uterine epithelial surface. A number of cell surface molecules have been implicated in the initial attachment reaction between trophectoderm and maternal surface epithelium, these include heparin-binding epidermal growth factor (HB-EGF), trophinin, CD44, integrins and extra cellular matrix molecules such as osteopontin (OPN) each of which exhibit elevated levels of expression at the time of implantation. CD44 is a membrane glycoprotein that is present in a variety of isoforms and is considered to be the major cell surface receptor for hyaluronan. The aim of these work was to study the effect of CD44 on embryo implantation. The rabbit is potentially an excellent model for study of implantation because it is an obligate ovulator, and therefore pregnancy can be precisely timed. Adult New Zealand rabbit females (n=12) were naturally inseminated with a buck of proven fertility. The day of coitus was counted as ‘Day 0’ of pregnancy. To determine the effect of CD44 at the time of implantation, the animals were divided in three groups: group A (four animals): received 100μg of anti-CD44/mL in an intraperitoneal injection on day 4.5 of pregnancy; group B (four animals), via mid-ventral laparotomies on day 6.5 p.c animals received an injection of 20μg of anti-CD44 on the right horn (0.5mL each, from the ovarian end to the cervix). All these treatments were performed in the right horn. Each animal served as her own control with the left uterine horn receiving 0.5mL of saline. Group C (four animals): This was the control group; two animals received an injection of 2mL of saline and the other two received 0.5mL of saline in each uterine horn. Finally, each animal was sacrificed on Day 10 of the pregnancy, the uterus was removed, and the number of implants were counted in each uterine horn. In the group A: a mean of 4.5±0.47 s.e.m implants were found in the right and on the left side. In group B, a profound reduction in implantation sites was found with the anti-CD44 injected into the uterine horn, a mean of 0 implants in the right uterine horn compared with 3.5 implants on the left side P&lt;0.0001. Group C showed 4.25 implants on the right horn and 5.5 on the left horn; no statistical differences were found. Conclusion: the intraperitoneal injection of the anti-CD44 slightly reduced the number of embryos implanted but this reduction was not statistically significant. Anti-CD44 injected intrauterine affected seriously the embryo survival at the time of implantation.

scholarly journals Clinical, Molecular and Histopathological Evaluation of the Effect Autologus PRP & PRF on the Second Intension Wound Healing in Dogs

2021 ◽  
Author(s):  
Olla Khalifa ◽  
Abdelhaleem Elkasapy ◽  
Eman Sallam ◽  
Adel Alakraa ◽  
Yasmin Marie ◽  
...  
Keyword(s):  
Wound Healing ◽  
Histopathological Examination ◽  
Saline Control ◽  
Control Group ◽  
High Positive Correlation ◽  
Cutaneous Injury ◽  
Group A ◽  
The Difference ◽  
Group B ◽  
The Right

Abstract A new trend of regenerative medicine was introduced recently in the field of second intension wound healing. The PRP and PRF represented a corner stone in this clinical practice, were it admit many factors for acceleration of wound healing, enhancement of wound epithelization and neovascularization. PRP and PRF are considered as a great concentrated source of growth factors (PDGF, TGF-β, VEGF, bFGF) and cytokines which are fundamental fro wound healing. Nine adult dogs were used in this study; we induced a 3cm diameter full thickness cutaneous injury at the right chest region. The animals were divided into three groups equally and the wounds were treated twice weekly for three successive weeks. Group A received only normal saline (control group). The members of second group treated by PRP (group B) while, the group C treated by PRF. Clinical evaluation, Molecular studies of IL10 & TGF-β and histopathological examination were used to demonstrate the difference between the three treatment regimes. Results showed non-significant negative low correlation between loss of weight and WHR%, and showed significant high positive correlation between treatment cost either by PRP or PRF with IL10 (0.79*) and WHR%(0.996**). We concluded that the PRP and PRF exhibited higher regeneration capacity and accelerate the quality of wound healing. The PRP was more superior to PRF, but not significantly different. The IL10 was significant increase in expression in PRP, while TGF-b was non-significant increased in PRF group

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