Survivorship in Gynecologic Cancer: Enduring the Treatment toward a New Normal

2014 ◽  
pp. e288-e294 ◽  
Author(s):  
Linda R. Duska ◽  
Amanda N. Fader ◽  
Don S. Dizon
Keyword(s):  
Early Detection ◽  
Health Outcomes ◽  
Cancer Diagnosis ◽  
Gynecologic Cancer ◽  
Gastrointestinal Function ◽  
Survivorship Care ◽  
Gynecologic Malignancies ◽  
Patient Centered ◽  
Psychosocial Challenges ◽  
Obesity And Cancer

Women are living longer after a cancer diagnosis because of advances in early detection and treatment. However, although our ability to effectively treat gynecologic malignancies has improved, survivors of gynecologic cancer often face profound physical, emotional, sexual, and psychosocial challenges as a result of their cancer diagnosis and treatment. In this article, we discuss how patient comorbidities (i.e., obesity) and cancer treatment effects may adversely affect sexual health outcomes, gastrointestinal function, and general health among survivors of gynecologic cancer. The importance of a multidisciplinary, patient-centered approach to survivorship care is emphasized.

Good fetal outcome of pregnancies with gynecologic cancer conditions: cases and literature review

2006 ◽  
Vol 16 (Suppl 1) ◽  
pp. 225-230 ◽  
Author(s):  
F. Ghaemmaghami ◽  
M. Hasanzadeh
Keyword(s):  
Cancer Diagnosis ◽  
Gynecologic Cancer ◽  
Multimodality Treatment ◽  
Fetal Outcome ◽  
Reproductive Age ◽  
Gynecologic Malignancies ◽  
Women Of Reproductive Age ◽  
Appropriate Treatment ◽  
Changes In Pregnancy ◽  
In Pregnancy

Gynecologic malignancies frequently occur in women of reproductive age and are estimated to complicate 1 in 1000 pregnancies. Cancer diagnosis may be delayed because of difficulties in distinguishing symptoms from physiologic changes in pregnancy. Another problem is applying the standard workup in pregnant women. These reports describe the good fetal outcome of pregnancies in patients with vulvar and ovarian carcinoma. Patients underwent multimodality treatment, and their infants were developmentally normal. Vulvar and ovarian cancer is a rare finding in pregnancy. Early diagnosis and appropriate treatment offer the best prognosis. Aggressive postoperative chemotherapy also continues to better the outcome.

scholarly journals Examining the impact of mental disease on type 2 diabetes outcomes: results from the EpiChron Cohort

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
I Guerrero Fernández de Alba ◽  
A Gimeno-Miguel ◽  
B Poblador Plou ◽  
K Bliek Bueno ◽  
J Carmona Pirez ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Substance Abuse ◽  
Early Detection ◽  
Health Outcomes ◽  
Emergency Room ◽  
Mental Disease ◽  
Emergency Room Visits ◽  
Mental Diseases ◽  
The Impact

Abstract Background Type 2 diabetes mellitus (T2D) is often accompanied by other chronic diseases, including mental diseases (MD). This work aimed at studying MD prevalence in T2D patients and analyse its impact on T2D health outcomes. Methods Retrospective, observational study of individuals of the EpiChron Cohort aged 18 and over with prevalent T2D at baseline (2011) in Aragón, Spain (n = 63,365). Participants were categorized by the existence or absence of MD, defined as the presence of depression, anxiety, schizophrenia or substance abuse. MD prevalence was calculated, and a logistic regression model was performed to analyse the likelihood of the four studied health outcomes (4-year all-cause mortality, all-cause hospitalization, T2D-hospitalization, and emergency room visits) based on the presence of each type of MD, after adjusting by age, sex and number of comorbidities. Results Mental diseases were observed in 19% of T2D patients, with depression being the most frequent condition, especially in women (20.7% vs. 7.57%). Mortality risk was significantly higher in patients with MD (odds ratio -OR- 1.24; 95% confidence interval -CI- 1.16-1.31), especially in those with substance abuse (OR 2.18; 95% CI 1.84-2.57) and schizophrenia (OR 1.82; 95% CI 1.50-2.21). The presence of MD also increased the risk of T2D-hospitalization (OR 1.51; 95% CI 1.18-1.93), emergency room visits (OR 1.26; 95% CI 1.21-1.32) and all-cause hospitalization (OR 1.16; 95% CI 1.10-1.23). Conclusions The high prevalence of MD among T2D patients, and its association with health outcomes, underscores the importance of providing integrated, person-centred care and early detection of comorbid mental diseases in T2D patients to improve disease management and health outcomes. Key messages Comprehensive care of T2D should include specific strategies for prevention, early detection, and management of comorbidities, especially mental disorders, in order to reduce their impact on health. Substance abuse was the mental disease with the highest risk of T2D-hospitalization, emergency room visits and all-cause hospitalization.

scholarly journals A Selective Ensemble Classification Method Combining Mammography Images with Ultrasound Images for Breast Cancer Diagnosis

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Jinyu Cong ◽  
Benzheng Wei ◽  
Yunlong He ◽  
Yilong Yin ◽  
Yuanjie Zheng
Keyword(s):  
Breast Cancer ◽  
Early Detection ◽  
Cancer Diagnosis ◽  
Breast Cancer Diagnosis ◽  
Ensemble Classification ◽  
Classification Method ◽  
Ultrasound Images ◽  
Selective Ensemble ◽  
Detection And Diagnosis ◽  
Early Detection And Diagnosis

Breast cancer has been one of the main diseases that threatens women’s life. Early detection and diagnosis of breast cancer play an important role in reducing mortality of breast cancer. In this paper, we propose a selective ensemble method integrated with the KNN, SVM, and Naive Bayes to diagnose the breast cancer combining ultrasound images with mammography images. Our experimental results have shown that the selective classification method with an accuracy of 88.73% and sensitivity of 97.06% is efficient for breast cancer diagnosis. And indicator R presents a new way to choose the base classifier for ensemble learning.

scholarly journals Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer

2021 ◽  
Vol 8 ◽  
Author(s):  
Su-Ju Wei ◽  
Li-Ping Wang ◽  
Jun-Yan Wang ◽  
Jing-Xu Ma ◽  
Feng-Bin Chuan ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Early Detection ◽  
Tumor Markers ◽  
Cancer Diagnosis ◽  
Diagnostic Value ◽  
Diagnostic Methods ◽  
Lung Cancer Diagnosis ◽  
Early Lung Cancer ◽  
Group A ◽  
Group B

Objective: The objective of this research is to explore the diagnostic value of imaging plus tumor markers in the early detection of lung cancer.Methods: Sixty patients with lung cancer treated in our hospital from January 2018 to January 2019 were selected as group A. They were matched with 60 patients with benign lung disease as group B and 60 healthy subjects examined in our hospital as group C. The carcino-embryonic antigen (CEA), CYFRA21-1, and neuron-specific enolase (NSE) were assessed, and the diagnostic value of tumor markers plus imaging in lung cancer diagnosis was explored.Results: The CEA, CYFRA21-1, and NSE in group A were evidently superior to those in groups B and C, and those in group B were superior to those in group C (all P < 0.001). CEA had the highest sensitivity (56.7%), and NSE had the highest specificity (93.3%). The tumor markers plus imaging had the highest sensitivity for different types of lung cancer, and the sensitivity to early lung cancer (90%) was superior to other diagnostic methods (P < 0.05).Conclusion: The tumor markers plus imaging is of great significance in early lung cancer diagnosis and provides a reference for judging the pathological classification.

Patient and Family Engagement in THE Conversation

2017 ◽  
pp. 93-113
Author(s):  
Jennifer Freytag ◽  
Richard L. Street Jr.
Keyword(s):  
Health Outcomes ◽  
End Of Life ◽  
End Of Life Care ◽  
Family Engagement ◽  
Future Research ◽  
Life Care ◽  
Patient Centered ◽  
Communication Framework ◽  
Communicative Functions ◽  
Main Ideas

This chapter uses a patient-centered communication framework to examine observational studies of patient and family engagement in communication about end-of-life care. It analyzes how the literature has connected communication with health outcomes in end-of-life care. Within this analysis, it brings together three main ideas. First, family plays an important and overlooked role in communication about end-of-life care. Second, the literature describes communication that serves multiple functions, and it describes the special challenges presented by end-of-life care communication. Finally, it links these communicative functions with health outcomes and outlines directions for future research.

scholarly journals Migrating techniques, multiplying diagnoses: the contribution of Argentina and Brazil to early 'detection policy' in cervical cancer

2010 ◽  
Vol 17 (suppl 1) ◽  
pp. 33-51 ◽  
Author(s):  
Yolanda Eraso
Keyword(s):  
Cervical Cancer ◽  
Early Detection ◽  
Cancer Diagnosis ◽  
Pap Smear ◽  
Diagnostic Techniques ◽  
Diagnostic Tools ◽  
South American ◽  
Pap Smear Test ◽  
Smear Test ◽  
Medical Centers

This article on the early detection of cervical cancer focuses on the development of two leading diagnostic techniques - colposcopy and the Pap smear test - and their histories in Argentina and Brazil. It explores how diagnostic tools were transferred between Europe and the Americas, while examining the intersection of cultural and medical aspects and the processes of adaptation and resignification in the receiving countries. Colposcopy received little attention in the main Western medical centers until South American countries reasserted its significance in the 1950s. 'Peripheral' centers played a central role in early detection policies and the combined uses of these methods gave rise to a new stage of 'cumulative confidence' in cervical cancer diagnosis and screening.

scholarly journals Systematic Review of the Impact of Cancer Survivorship Care Plans on Health Outcomes and Health Care Delivery

2018 ◽  
Vol 36 (20) ◽  
pp. 2088-2100 ◽  
Author(s):  
Paul B. Jacobsen ◽  
Antonio P. DeRosa ◽  
Tara O. Henderson ◽  
Deborah K. Mayer ◽  
Chaya S. Moskowitz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Health Outcomes ◽  
Health Care Delivery ◽  
Care Delivery ◽  
Cochrane Library ◽  
Survivorship Care Plan ◽  
Satisfaction With Care ◽  
Survivorship Care ◽  
Care Plans

Purpose Numerous organizations recommend that patients with cancer receive a survivorship care plan (SCP) comprising a treatment summary and follow-up care plans. Among current barriers to implementation are providers’ concerns about the strength of evidence that SCPs improve outcomes. This systematic review evaluates whether delivery of SCPs has a positive impact on health outcomes and health care delivery for cancer survivors. Methods Randomized and nonrandomized studies evaluating patient-reported outcomes, health care use, and disease outcomes after delivery of SCPs were identified by searching MEDLINE, Embase, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, and Cochrane Library. Data extracted by independent raters were summarized on the basis of qualitative synthesis. Results Eleven nonrandomized and 13 randomized studies met inclusion criteria. Variability was evident across studies in cancer types, SCP delivery timing and method, SCP recipients and content, SCP-related counseling, and outcomes assessed. Nonrandomized study findings yielded descriptive information on satisfaction with care and reactions to SCPs. Randomized study findings were generally negative for the most commonly assessed outcomes (ie, physical, functional, and psychological well-being); findings were positive in single studies for other outcomes, including amount of information received, satisfaction with care, and physician implementation of recommended care. Conclusion Existing research provides little evidence that SCPs improve health outcomes and health care delivery. Possible explanations include heterogeneity in study designs and the low likelihood that SCP delivery alone would influence distal outcomes. Findings are limited but more positive for proximal outcomes (eg, information received) and for care delivery, particularly when SCPs are accompanied by counseling to prepare survivors for future clinical encounters. Recommendations for future research include focusing to a greater extent on evaluating ways to ensure SCP recommendations are subsequently acted on as part of ongoing care.

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