scholarly journals Impact of Interdialytic Weight Gain (IDWG) on Nutritional Parameters, Cardiovascular Risk Factors and Quality of Life in Hemodialysis Patients

2015 ◽  
Vol 13 (1) ◽  
pp. 25-33 ◽  
Author(s):  
Aysegul Kahraman ◽  
Hakan Akdam ◽  
Alper Alp ◽  
Mustafa Ahmet Huyut ◽  
Cagdas Akgullu ◽  
...  

AbstractIntroduction. The amount of interdialytic weight gain (IDWG) considering body weight is of great importance in hemodialysis patients. In general practice, patients are asked to get standard weight between two hemodialysis sessions. However, it should be individualized considering patient’s weight. We aimed to determine the association between the IDWG and the nutritional parameters, cardiovascular risk factors, and quality of life.Methods. Thrity-two patients receiving hemodialysis at least for one year were enrolled into the study. Patients were monitored for 12 consecutive hemodialysis sessions; and the arithmetic mean of IDWG was calculated. IDWG% was calculated in accordance with patients’ dry weight. Data of patients with IDWG<3% (Group I) and IDWG≥3 (Group II) were compared. Sociodemographic variables, laboratory, anthropometric measurements, blood pressure, left ventricular mass index, Subjective Global Assessment Scale and SF-36 Quality of Life Scale were applied to evaluate the patients.Results. 59.4% (n=19) and 40.6% (n=13) of patients were included in Group I and Group II, respectively. In Group II, albumin (p=0.02), potassium (p=0.02), phosphorus (p=0.04), nPCR (p=0.03), physical function (p=0.04), role limitations caused by physical problems (p=0.04), general health (p=0.03), physical quality of life (p=0.04) scores were significantly higher. A significant correlation was detected between IDWG and physical and mental quality of life, total score SF-36, albumin, total protein and the potassium values.Conclusions. Patients with an IDWG ≥ 3% have better nutritional parameters and quality of life scales. The limiting of IDWG to 1-2 kg, ingoring patient weight may give rise to malnutrition and a reduced quality of life.

2018 ◽  
Vol 3 (3) ◽  
pp. 2473011418S0023
Author(s):  
Florian Grubhofer ◽  
Stephan Wirth

Category: Hindfoot Introduction/Purpose: Swelling and pain are common after foot and ankle procedures. We hypothesized that compressive stockings (CS) treatment after hindfoot surgery would positively influence patient outcomes. Methods: We undertook this randomized controlled trial in 87 consecutive patients to analyze the clinical effect of CS after hindfoot and ankle surgery and evaluate CS-wearing compliance using sensors that were implanted into CS. Ankle swelling, pain status, quality of life (SF-36 score), and the American Orthopaedic Foot & Ankle Score (AOFAS) were set as the primary end points. The CS wearing time in hours and percentage were investigated as the secondary end points. All participants with CS (group I) were informed about the implanted sensor after the CS were taken off. A subgroup analysis of group I was performed to detect differences between patients with high vs low compliance. Results: At 12 weeks, the results of ankle swelling (mean 234 mm in group I and 232 mm in group II), pain in the visual analog scale (1.7 group I vs 1.9 in group II), the SF-36 score (38 points in group I vs 30 points in group II), and the AOFAS score (a mean of 76 points in both groups) showed no statistical differences between the 2 groups. The mean wearing time was 136 (range, 0-470) hours, which corresponds to a compliance rate of 65%. Sixteen participants had high compliance (>80%, >170 hours), and 21 patients had low or noncompliance. The clinical results of patients with high wearing compliance were not significantly better compared to the results of patients with low compliance. Conclusion: CS therapy after ankle and hindfoot surgery was associated with a low wearing compliance and did not influence ankle swelling, function, pain, and the quality of life compared to the control group. Furthermore, the clinical results of patients with high compliance were not better compared to the results of patients with low or noncompliance wearing behavior.


2019 ◽  
Vol 0 (Avance Online) ◽  
Author(s):  
Grace Fernanda Nunes ◽  
Luis Cuadrado Martins ◽  
Roberto Jorge da Silva Franco ◽  
Ivani Morales Xavier ◽  
Monica Marcelli de Souza ◽  
...  

Resumo Objetivo: Avaliar a associação entre nível de atividade física e fatores de risco cardiovascular, qualidade de vida e comorbidades dos pacientes hipertensos em Agudos (São Paulo - Brasil). Método: Foram avaliados 200 pacientes hipertensos e verificadas as associações entre Questionário Internacional de Atividade Física IPAQ, questionário de qualidade de vida SF-36, fatores de risco cardiovascular e comorbidades. Resultados: O nível de atividade física associou-se à qualidade de vida nos domínios capacidade funcional, limitações físicas e estado geral de saúde. Houve associação entre o nível de atividade física e qualidade de vida, mesmo ajustando-se para as variáveis de confusão (idade, sexo, profissão, acidente vascular encefálico prévio, internação previa por insuficiência cardíaca congestiva e diabetes). Conclusão: O nível de atividade física em hipertensos e diabéticos foi inferior ao desejado e associou-se a fatores de risco cardiovascular, comorbidades e vários indicadores de qualidade de vida. Resumen Objetivo: Evaluar la asociación entre nivel de actividad física y factores de riesgo cardiovascular, calidad de vida y comorbilidades de los pacientes del programa de atención a pacientes hipertensos en Agudos (São Paulo-Brasil). Método: 200 pacientes hipertensos fueron evaluados y se valoró la asociación entre el nivel de actividad física (mediante el Cuestionario Internacional de Actividad Física IPAQ), la calidad de vida (mediante el cuestionario SF-36), los factores de riesgo cardiovascular y las comorbilidades. Resultados: El nivel de actividad física se asoció con la calidad de vida en los ítems de capacidad funcional, limitaciones físicas y estado general de salud. Se obtuvo asociación entre el nivel de actividad física y dichos ítems de calidad de vida, independientemente de las variables de confusión (edad, sexo, profesión, accidente vascular encefálico previo, internamiento previo por insuficiencia cardíaca congestiva y diabetes). Conclusión: El nivel de actividad física en pacientes hipertensos y diabéticos fue menor de lo deseado y se asoció con factores de riesgo cardiovascular, comorbilidades y diversos indicadores de calidad de vida. Abstract Objetive: To evaluate the association between physical activity level and cardiovascular risk factors, quality of life, and comorbidities of hypertensive patients in Agudos (São Paulo-Brazil). Method: 200 hypertensive patients were evaluated and the associations between international physical activity Questionnaire IPAQ, questionnaire of quality of life SF-36, cardiovascular risk factors and comorbidities were verified. Results: The level of physical activity was associated with the quality of life in the areas functional capacity, physical limitations and general state of health. There was association between the level of physical activity and quality of life, even adjusting for the confounding variables. Conclusion: The level of physical activity in hypertensive and diabetic patients was lower than desired and was associated with cardiovascular risk factors, comorbidities and several indicators of quality of life.


2021 ◽  
pp. 345-351
Author(s):  
Iryna SHMAKOVA ◽  
Svitlana PANINA ◽  
Volodymyr MYKHAYLENKO

Introduction. Comorbidity is an independent risk factor for mortality and significantly influences the prognosis and quality of life. Purpose: to evaluate the impact of high-tone HiTOP 4 touch therapy on cognitive disorders and quality of life in the complex treatment of patients with comorbid pathology. Methods: complex treatment of 2 groups of patients with inclusion in the basic treatment regimen of high-tone therapy was carried out - a total of 80 patients (men - 34, women - 46) aged 41 to 79 years old, group I - patients with hypertension and chronic cerebral ischemia (CСI) - 38 patients and group II - patients with hypertension, CСI and concomitant diabetes mellitus (DM) type 2 - 42 patients. The average age in group I was 61.5, in group II - 65.5. Group I received lisinopril and amlodipine in one tablet, group II received metformin in addition to the above therapy. Both groups received a course of 10 sessions of high-tone therapy using the device HiTOP 4 touch (Germany) according to the general method: 2 electrodes on the feet, 2 on the forearms and one on the neck-collar area. All the patients were assessed for their cognitive condition, degree of anxiety and depression, and estimated for quality of life before and after a course of high-tone therapy. In order to do this, we used valid assessment tests, such as the Montreal Cognitive Assessment Scale (MoCA), the Hospital Anxiety and Depression Scale (HADS), and the SF-36 Quality of Life Questionnaire. Results: the course of high-tone therapy for patients with hypertension and CCI led to improved quality of life, on all indicators of the SF-36 scale, except for pain intensity, increased cognitive functions by 3.52 points on the MoCA scale, reduced anxiety by 2.06 points and depression by 1.92 points on the HADS scale. The course of high-tone therapy for patients with CCI, hypertension and type 2 DM resulted in a significant improvement of 5 out of 8 quality of life indicators on the SF-36 scale, cognitive functions by 2.27 points on the MoCA scale and reduced anxiety by 4.3 points, and depression by 0.53 points on the HADS scale. Conclusion: the inclusion of high-tone therapy in the complex treatment of patients with comorbid pathology improves cognitive functions, reduces anxiety and depression, improves quality of life. Keywords: comorbid pathology, high-tone therapy, cognitive functions, anxiety, depression, quality of life,


2020 ◽  
Vol 14 (3) ◽  
pp. 155798832091725
Author(s):  
Jeong Kyun Yeo ◽  
Ho Seok Koo ◽  
Jihyeong Yu ◽  
Min Gu Park

Testosterone deficiency (TD) is common and impairs quality of life (QoL) in patients with chronic kidney disease (CKD). However, there are no studies about whether testosterone replacement therapy (TRT) can improve QoL in patients with CKD. Therefore, we investigated the effect of TRT on the QoL of patients with CKD and confirmed the safety of TRT. Twenty-five male patients with stages III–IV CKD whose serum testosterone levels were <350 ng/dl (TD) were enrolled and treated with testosterone gel for 3 months (group II). Age-matched controls with stages III–IV CKD and TD (group I) were recommended to exercise for the same period. Before and after the treatment, the BMI and handgrip strength were checked, serological tests were performed, and questionnaires were administered in both groups. Compared to baseline, there was no significant difference in serum testosterone levels, scores of the 36-Item Short Form Health Survey (SF-36), Aging Males’ Symptoms Scale (AMS), and International Prostate Symptom Score (IPSS), and grip strength in group I after 3 months. In group II, a significant increase in testosterone, hemoglobin (Hb), and hematocrit (Hct) was observed, and grip strength significantly increased after TRT. Significant improvement in scores of SF-36, AMS, and IPSS was also confirmed after TRT in group II. There was a significant difference in testosterone, Hb, Hct, grip strength, and scores of SF-36, AMS, and IPSS between the two groups after 3 months. The patients in group II showed positive results and continued with TRT. Therefore, we conclude that TRT safely improves the QoL and TD symptoms in patients with moderate-to-severe CKD.


2017 ◽  
Vol 10 (3) ◽  
pp. 236-240
Author(s):  
Maxim Borisovich Polyansky ◽  
Dmitry Petrovich Nazarenko ◽  
Tatjana Aleksandrovna Ishunina ◽  
Dmitrii Igorevich Kolmykov

Relevance. The number of elderly patients with acute cholecystitis is constantly increasing, in spite of the success achieved in the diagnosis and treatment of this pathology. The possibilities for radical treatment of patients with high operational anesthesia risk are substantially limited. The aim of the study was to conduct comparative analysis of the quality of life of patients after transcutaneous-transhepaticmicrocholecystostomy and traditional cholecystostomy with thermal mucoclasia of the gallbladder. Materials and methods. The quality of life of 31 patients with high operational anesthesia risk following transcutaneous-transhepaticmicrocholecystostomy (TTMC) and traditional cholecystostomy with thermal mucoclasia of the gallbladder (TCTMG), was studied. All patients were divided into two groups: the first group consisted of 20 (64.5%) patients who underwent TTMC, the second one included 11 (35.5%) patients who underwent TCTMG. Quality of life of patients was studied with the help of the questionnaire using the SF-36 Health Status Survey 4 months after TTMC or TCTMG. Statistical processing of the results was carried out using the program Microsoft Office Excel -2013. Results and its discussion. The physical component of health (physical functioning, role functioning due to physical condition, pain intensity, general health) was 64.25% higher in patients of Group II than in patients of Group I (p = 0.001), and the psychological Health component (mental health, role functioning due to emotional state, social functioning, vital activity) was also (68.05%) higher in Group II (p = 0.004).   Conclusions. The use of the method of thermal mucoclasia of the gallbladder in patients with high operational anesthesia risk allows to achieve higher quality indices compared to patients who underwent TTMC, since after demucotization of the gallbladder cavity it is obliterated due to hyperplasia of the connective tissue of the lamina propria or submucosa, thereby finally solving the problem of acute cholecystitis in this category of patients.


2018 ◽  
Vol 85 (7) ◽  
pp. 5-8
Author(s):  
V. V. Grubnik ◽  
N. R. Paranyak ◽  
V. V. Grubnik ◽  
V. V. Ilyashenko

Objective. Studying of possibility of application of a self-fixing mesh ProGrip™ while plasty performing for large hiatal hernias (HH).Маterials and methods. In the investigation 144 patients, ageing 30 – 78 yrs old, owing HH with square 10 - 20 сm2, took part. The patients were divided into two groups. Group I consisted of 71 patients, to whom crurorhaphy with additional strengthening of the sutures, using a self-fixing mesh ProGrip™ was peformed. Group II consisted of 73 patients, in whom sutures of crurorhaphy were not strengthened by the mesh implant. Dynamical follow-up in patients was conducted in 3, 6, 12, 24, 36, 48 and 60 mo after the surgical treatment.Results. Average duration of the operation in patients of Group i and Group II did not differ essentially – (94 ± 12) and (92 ± 15) min, accordingly (p > 0.1). In late terms of follow-up the HH recurrence have occurred in 3.2% in the Group I patients and in 21.5% - in the Group II patients. The quality of life index in patients of Group I, in accordance to questionnaire SF-36, was trustworthily better, than in patients of Group II (p < 0.05).Conclusion. The mesh ProGrip™ application while doing plasty of large HH permits to lower the recurrence rate significantly and to improve the operative interventions results essentially.


2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1147.2-1147
Author(s):  
S. Jriri ◽  
S. Boussaid ◽  
S. Rekik ◽  
M. Abbes ◽  
M. Ben Majdouba ◽  
...  

Background:The level of the Health-related quality of life (HRQL) in patients with rheumatoid arthritis (RA) is often negleglected in their medical care. While, theese patients are suffering from a precarious quality of life, resulting from pain, impaired physical function and fatigue. The use of biological agents for treating this disease is then a challenge, leading to the possibility of reducing the consequences of the disease.Objectives:The main purpose of this study was to compare the level of HRQL in patients with rheumatoid arthritis (RA) during therapy applying disease-modifying antirheumatic drugs (DMARDs) with conventional synthetics (csDMARDs) or with csDMARDs in combination with biological drugs (bDMARDs).Methods:The study involved 120 patients with RA, divided into two groups: group I –treated using csDMARDs (combination therapy: methotrexate and salazopyrine), group II – using csDMARDs in association with bDMARDs which included TNF inhibitors (etanercept and adalimumab). All the studied patients were surveyed with the use of the following questionnaires: the short-form health survey (SF-36) for HRQL that assesses eight domains: functional capacity (ten items), physical aspects (four items), pain (two items), general health (five items), vitality (four items), social aspects (two items), emotional issues (three items) and mental health (five items), in addiction to one item to compare current health status and that of the previous year, The AIMS2-SF, and Health Assessment Questionnaire (HAQ). The questionnaires were filled out at the consultation after patient’s consent.The 28-Joint Disease Activity Score (DAS-28) was calculated.Results:Group I consisted of 72 persons including 55 women and 17 men with a mean age of 58.4 years. Group II contaned 48 patients where females predominated (sex ratio: 0.3), the mean age was 52.4 years. The majority of patients (53.3%) had been diagnosed with RA for more than five years. Most of the SF-36 domains showed significant improvement in the second group (p<0.01), highlighting the social aspects, pain, physical functioning, emotional issues, vitality and physical aspects. The mean score of HAQ II decreased from 1.97 up to 1.23 with biological therapy (p<0.01). The highest AIMS scores were comparatively in the two groups (I vs II): in social activity (6.49±1.93 vs 6.23±1.56), pain (4.70±2.04 vs 4.01±2), depression (4.70±2.23 vs 4.66±2.03), and physical activity (4.03±2.10 vs 4.01±2.08). The DAS-28 value, the number of swollen joints, and the duration of morning stiffness were significantly smaller among patients from group II (P=0.04). After logistical regression,treatement with biotherapy was isolated as a fundamental independent factor influencing the mentel component of SF-36 scale with an OR of 1.59.Conclusion:we conclude that the use of biologic therapy in patients with RA proved to be an important pharmacological strategy for improving HRQL and functional capacity as assessed by the HAQ II and SF-36 instruments.The intensity of the activity of RA as well as experiencing pain and the duration of morning stiffness were smaller among patients applying csDMARDs plus bDMARDs compared with patients treated only with csDMARDs.References:[1]Blair, H. A., & Deeks, E. D. (2016). Infliximab Biosimilar (CT-P13; Infliximab-dyyb): A Review in Autoimmune Inflammatory Diseases. BioDrugs, 30(5), 469–480.[2]Araújo, F., Gonçalves, J., & Fonseca, J. E. (2016). Biosimilar DMARDs: What Does the Future Hold? Drugs, 76(6), 629–637.Disclosure of Interests:None declared


Author(s):  
M. M. Halei ◽  
I. Ya. Dziubanovskyi ◽  
I. P. Marchuk

Gallstone disease is quite common in the adult population and can quickly cause life-threatening conditions that require extensive surgical treatment. In recent years, the assessment of quality of life is becoming increasingly important in world medicine as an indicator of the general condition of the patient and the effectiveness of treatment and rehabilitation measures. The aim of this work – to collect and calculate indicators of quality of life in postoperative patients with gallstones of gall bladder and common bile duct; to compare data from patients with open and laparoscopic treatment; to determine the advantages of the treatment methods. For rating quality of life 36-Item Short-Form Health Status (SF-36) was used. The statistic was collected using retrospective analysis of worked out data in laparoscopic surgery unit in Volynian regional state hospital during 2016–2019 (191 patients). Patients of group I (113 patients) underwent laparoscopic treatment, patients of group II used open surgical treatment (78 people). Statistical processing was performed using the program “Statistica 6.0” (Statsoft Inc., USA). In group I pain level in first two hours was significantly lower than in group II (6.2 vs 8.4 in 10 point scale), in addition, pain relief became faster reaching low pain level of abdomen in 2.48 days. In group II pain level was higher (8.4 points) and pain relief was reached in 5.11 days. Oral nutrition and verticalisation were renewed in 14.7±3.1 hours in group I, and in 22.9±5,5 hours in group II and 6.1±1,9 hours in group I vs 19.7±3,3 hours in group II. Also, according the results SF-36, quality of life indicators indicate faster recovery in the group of laparoscopic treatment compared to the group with the classic version of the operation. The physical functioning and physical performance of the role differed significantly in favor of laparoscopic treatment throughout the follow-up period. Pain indicators in the first group were satisfactory after 1 month of rehabilitation, while in the second group such indicators were achieved only after 6 months – 91/94/94 vs. 74/89/94. Although psychological well-being differed between 1 and 3 months, in favor of minimally invasive treatment, after 6 months the data were comparable in both groups.


2017 ◽  
Vol 39 (2) ◽  
pp. 210-218 ◽  
Author(s):  
Florian Grubhofer ◽  
Sabrina Catanzaro ◽  
Regula Schüpbach ◽  
Mohamed A. Imam ◽  
Stephan Wirth

Background: Swelling and pain are common after foot and ankle procedures. We hypothesized that compressive stockings (CS) treatment after hindfoot surgery would positively influence patient outcomes. Methods: We undertook this randomized controlled trial in 87 consecutive patients to analyze the clinical effect of CS after hindfoot and ankle surgery and evaluate CS-wearing compliance using sensors that were implanted into CS. Ankle swelling, pain status, quality of life (SF-36 score), and the American Orthopaedic Foot & Ankle Score (AOFAS) were set as the primary end points. The CS wearing time in hours and percentage were investigated as the secondary end points. All participants with CS (group I) were informed about the implanted sensor after the CS were taken off. A subgroup analysis of group I was performed to detect differences between patients with high vs low compliance. Results: At 12 weeks, the results of ankle swelling (mean 234 mm in group I and 232 mm in group II), pain in the visual analog scale (1.7 group I vs 1.9 in group II), the SF-36 score (38 points in group I vs 30 points in group II), and the AOFAS score (a mean of 76 points in both groups) showed no statistical differences between the 2 groups. The mean wearing time was 136 (range, 0-470) hours, which corresponds to a compliance rate of 65%. Sixteen participants had high compliance (>80%, >170 hours), and 21 patients had low or noncompliance. The clinical results of patients with high wearing compliance were not significantly better compared to the results of patients with low compliance. Conclusion: CS therapy after ankle and hindfoot surgery was associated with a low wearing compliance and did not influence ankle swelling, function, pain, and the quality of life compared to the control group. Furthermore, the clinical results of patients with high compliance were not better compared to the results of patients with low or noncompliance wearing behavior. Level of Evidence: Level II, prospective randomized study of lower quality.


2015 ◽  
Vol 25 (1) ◽  
pp. 135-140 ◽  
Author(s):  
Kavitha M. Chinnaiyan ◽  
Ann M. DePetris ◽  
Judith A. Boura ◽  
Korana Stakich-Alpirez ◽  
Scott S Billecke

Background: We sought to study the feasibility of establishing a comprehensive, mostly self-directed yoga program in a hospital and its dose-effect relationship on cardiovascular risk factors and quality of life (QoL) measures over six months. Methods: Yoga-based techniques (Advanced Yoga Practices; AYP; advancedyogapractices.com) were taught in 12 biweekly group sessions and self-directed practice at home was emphasized. Cardiovascular risk factors were elucidated by interview and review of medical history. Quality of life (QoL) outcomes included the SF-36, the Cohen Perceived Stress Scale (CPSS), and the Hospital Anxiety and Depression Scale (HADS). Risk factors and QoL measures were compared in participants at baseline and six months, as well as between those practicing ≥ 7 times versus &lt; 7 times per week. Results: A total of 22 individuals (19 women, mean age 59 ± 8.7 years) completed the study. At six months, changes were noted in the Mental Component Scale (MCS) of the SF-36 (p=0.0004) and the CPSS (p = 0.022). A greater improvement in CPSS was noted in those practicing ≥ 7 times versus &lt; 7 times a week (p=0.045). No changes were noted in cardiovascular risk factors. Conclusions: The prescription of a self-directed yoga program was feasible in a hospital setting and resulted in improvement in QoL measures at six months. Practicing more than seven times per week correlated with greater improvement in the perception of stress. Thus, at least a once-daily dose of AYP techniques for a significant improvement in perceived stress is an appropriate dose to employ and study in hospital settings.


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