scholarly journals Experimental studies on 3D printing of barium titanate ceramics for medical applications

2016 ◽  
Vol 2 (1) ◽  
pp. 95-99 ◽  
Author(s):  
Mark Schult ◽  
Eric Buckow ◽  
Hermann Seitz

AbstractThe present work deals with the 3D printing of porous barium titanate ceramics. Barium titanate is a biocompatible material with piezoelectric properties. Due to insufficient flowability of the starting material for 3D printing, the barium titanate raw material has been modified in three different ways. Firstly, barium titanate powder has been calcined. Secondly, flow additives have been added to the powder. And thirdly, flow additives have been added to the calcined powder. Finally, a polymer has been added to the three materials and specimens have been printed from these three material mixtures. The 3D printed parts were then sintered at 1320°C. The sintering leads to shrinkage which differs between 29.51–71.53% for the tested material mixtures. The porosity of the parts is beneficial for cell growth which is relevant for future medical applications. The results reported in this study demonstrate the possibility to fabricate porous piezoelectric barium titanate parts with a 3D printer that can be used for medical applications. 3D printed porous barium titanate ceramics can especially be used as scaffold for bone tissue engineering, where the bone formation can be promoted by electrical stimulation.

2020 ◽  
Vol 16 ◽  
Author(s):  
Wei Liu ◽  
Shifeng Liu ◽  
Yunzhe Li ◽  
Peng Zhou ◽  
Qian ma

Abstract:: Surgery to repair damaged tissue, which is caused by disease or trauma, is being carried out all the time, and a desirable treatment is compelling need to regenerate damaged tissues to further improve the quality of human health. Therefore, more and more research focus on exploring the most suitable bionic design to enrich available treatment methods. 3D-printing, as an advanced materials processing approach, holds promising potential to create prototypes with complex constructs that could reproduce primitive tissues and organs as much as possible or provide appropriate cell-material interfaces. In a sense, 3D printing promises to bridge between tissue engineering and bionic design, which can provide an unprecedented personalized recapitulation with biomimetic function under the precise control of the composition and spatial distribution of cells and biomaterials. This article describes recent progress in 3D bionic design and the potential application prospect of 3D printing regenerative medicine including 3D printing biomimetic scaffolds and 3D cell printing in tissue engineering.


Crystals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 353
Author(s):  
Yanting Han ◽  
Qianqian Wei ◽  
Pengbo Chang ◽  
Kehui Hu ◽  
Oseweuba Valentine Okoro ◽  
...  

Hydroxyapatite (HA) and HA-based nanocomposites have been recognized as ideal biomaterials in hard tissue engineering because of their compositional similarity to bioapatite. However, the traditional HA-based nanocomposites fabrication techniques still limit the utilization of HA in bone, cartilage, dental, applications, and other fields. In recent years, three-dimensional (3D) printing has been shown to provide a fast, precise, controllable, and scalable fabrication approach for the synthesis of HA-based scaffolds. This review therefore explores available 3D printing technologies for the preparation of porous HA-based nanocomposites. In the present review, different 3D printed HA-based scaffolds composited with natural polymers and/or synthetic polymers are discussed. Furthermore, the desired properties of HA-based composites via 3D printing such as porosity, mechanical properties, biodegradability, and antibacterial properties are extensively explored. Lastly, the applications and the next generation of HA-based nanocomposites for tissue engineering are discussed.


2020 ◽  
Vol 6 (1) ◽  
pp. 57-69
Author(s):  
Amirhosein Fathi ◽  
Farzad Kermani ◽  
Aliasghar Behnamghader ◽  
Sara Banijamali ◽  
Masoud Mozafari ◽  
...  

AbstractOver the last years, three-dimensional (3D) printing has been successfully applied to produce suitable substitutes for treating bone defects. In this work, 3D printed composite scaffolds of polycaprolactone (PCL) and strontium (Sr)- and cobalt (Co)-doped multi-component melt-derived bioactive glasses (BGs) were prepared for bone tissue engineering strategies. For this purpose, 30% of as-prepared BG particles (size <38 μm) were incorporated into PCL, and then the obtained composite mix was introduced into a 3D printing machine to fabricate layer-by-layer porous structures with the size of 12 × 12 × 2 mm3.The scaffolds were fully characterized through a series of physico-chemical and biological assays. Adding the BGs to PCL led to an improvement in the compressive strength of the fabricated scaffolds and increased their hydrophilicity. Furthermore, the PCL/BG scaffolds showed apatite-forming ability (i.e., bioactivity behavior) after being immersed in simulated body fluid (SBF). The in vitro cellular examinations revealed the cytocompatibility of the scaffolds and confirmed them as suitable substrates for the adhesion and proliferation of MG-63 osteosarcoma cells. In conclusion, 3D printed composite scaffolds made of PCL and Sr- and Co-doped BGs might be potentially-beneficial bone replacements, and the achieved results motivate further research on these materials.


2007 ◽  
Vol 46 (10B) ◽  
pp. 7039-7043 ◽  
Author(s):  
Satoshi Wada ◽  
Kotaro Takeda ◽  
Tomomitsu Muraishi ◽  
Hirofumi Kakemoto ◽  
Takaaki Tsurumi ◽  
...  

2022 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Ramesh Chand ◽  
Vishal S. Sharma ◽  
Rajeev Trehan ◽  
Munish Kumar Gupta

Purpose A nut bolt joint is a primary device that connects mechanical components. The vibrations cause bolted joints to self-loosen. Created by motors and engines, leading to machine failure, and there may be severe safety issues. All the safety issues and self-loosen are directly and indirectly the functions of the accuracy and precision of the fabricated nut and bolt. Recent advancements in three-dimensional (3D) printing technologies now allow for the production of intricate components. These may be used technologies such as 3D printed bolts to create fasteners. This paper aims to investigate dimensional precision, surface properties, mechanical properties and scanning electron microscope (SEM) of the component fabricated using a multi-jet 3D printer. Design/methodology/approach Multi-jet-based 3D printed nut-bolt is evaluated in this paper. More specifically, liquid polymer-based nut-bolt is fabricated in sections 1, 2 and 3 of the base plate. Five nuts and bolts are fabricated in these three sections. Findings Dimensional inquiry (bolt dimension, general dimensions’ density and surface roughness) and mechanical testing (shear strength of nut and bolt) were carried out throughout the study. According to the ISO 2768 requirements for the General Tolerances Grade, the nut and bolt’s dimensional examination (variation in bolt dimension, general dimensions) is within the tolerance grades. As a result, the multi-jet 3D printing (MJP)-based 3D printer described above may be used for commercial production. In terms of mechanical qualities, when the component placement moves from Sections 1 to 3, the density of the manufactured part decreases by 0.292% (percent) and the shear strength of the nut and bolt decreases by 30%. According to the SEM examination, the density of the River markings, sharp edges, holes and sharp edges increased from Sections 1 to 3, which supports the findings mentioned above. Originality/value Hence, this work enlightens the aspects causing time lag during the 3D printing in MJP. It causes variation in the dimensional deviation, surface properties and mechanical properties of the fabricated part, which needs to be explored.


Author(s):  
Tejinder Kaur ◽  
Suruchi Singh

Malvidin belongs to the class of anthocyanidin, a pigment compound present in fruits and vegetables like the colored berries, flowers, and vegetables which have pigments on it and it is available commercially as malvidin chloride. Malvidin is known to possess many medicinal characteristics like anti-microbial, anti-diabetic, anti-inflammatory, anti-obesity, and anti-cancer. In this research paper, a 3D printing technique is used which evolves a 3D printer based on desktop that extrudes tablets comprising the active drug which here is malvidin our main ingredient and the other excipients which are used as binders and disintegrants. Methods which are adapted here for the formulation of 3D printed tablet make the tablets appropriate for immediate and sustained release with its definite physical and mechanical properties like hardness, friability, and weight. Tablets that are extruded by the 3D printer are controlled release bi-layer tablets. Due to involvement of 3D printer, printing cost for the bi-layered tablets found very low that makes our method as cost efficient.


History of additive manufacturing started in the 1980s in Japan. Stereolithography was invented first in 1983. After that tens of other techniques were invented under the common name 3D printing. When stereolithography was invented rapid prototyping did not exists. Tree years later new technique was invented: selective laser sintering (SLS). First commercial SLS was in 1990. At the end of 20t century, first bio-printer was developed. Using bio materials, first kidney was 3D printed. Ten years later, first 3D Printer in the kit was launched to the market. Today we have large scale printers that printed large 3D objects such are cars. 3D printing will be used for printing everything everywhere. List of pros and cons questions rising every day.


2010 ◽  
Vol 57 (4(1)) ◽  
pp. 897-901
Author(s):  
Petr Pulpan ◽  
Rintaro Mori ◽  
Satoshi Wada ◽  
Hiroshi Hayashi ◽  
Yoshitaka Nagamori ◽  
...  

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