Management in cases of large uterine myomas in pregnancy

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Aleksandra Stupak ◽  
Marcin Bobiński ◽  
Andrzej Miturski ◽  
Barbara Kalbarczyk ◽  
Anna Kwaśniewska ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Pain Control ◽  
Clinical Observation ◽  
Uterine Fibroids ◽  
Reproductive Organs ◽  
Benign Tumors ◽  
Premature Delivery ◽  
Case Presentation ◽  
Uterine Myomas ◽  
In Pregnancy

AbstractObjectivesUterine fibroids are the most common benign tumors in women of procreative age. The effects of their occurrence affect the course of pregnancy by increasing the frequency of abortions, premature delivery or premature abruption of the placenta. Medical treatment includes clinical observation, pharmacological pain control, myomectomy during pregnancy or perinatal hysterectomy.Case presentationWe present a survey of literature and the case of a pregnant woman with an enormous uterine fibroid 23×13×16 cm on the basis of which a diagnostic-therapeutic scheme for tumors of the reproductive organs during pregnancy has been developed.ConclusionsThe study presents improved recommendations for management the pregnancies in presence of the uterine myomas based on clinical practice.

Cholangiocarcinoma in pregnancy (clinical case)

2020 ◽  
pp. 19-27
Author(s):  
A. Yu. Ralnikova ◽  
V. F. Bezhenar ◽  
B. V. Arakelyan ◽  
N. A. Tatarova ◽  
M. E. Malysheva
Keyword(s):  
Pregnant Woman ◽  
Clinical Case ◽  
Clinical Observation ◽  
Late Diagnosis ◽  
Biliary Cancer ◽  
In Pregnancy

The article discusses the problems of diagnosing biliary cancer during pregnancy, proceeding under the guise of complications associated with gestation. A clinical observation of late diagnosis of cholangiocarcinoma in a pregnant woman is presented.

scholarly journals HEALTHY AND PATHOLOGICAL CHANGES OF MYOMETRIUM: PREGNANT MYOMETRIUM, UTERINE FIBROIDS AND LEIOMYOSARCOMA. Cambios normales y patológicos del miometrio: miometrio del embarazo, fibrosis uterina y leiomiosarcoma

2016 ◽  
Vol 4 (1) ◽  
pp. 7-13
Author(s):  
Pasquapina Ciarmela ◽  
Soriful Islam ◽  
Pasquale Lamanna ◽  
Andrea Tranquilli ◽  
Mario Castellucci
Keyword(s):  
Smooth Muscle ◽  
Uterine Fibroids ◽  
Present Review ◽  
Benign Tumors ◽  
Pathological Changes ◽  
Uterine Smooth Muscle ◽  
Smooth Muscle Tumors ◽  
In Pregnancy

El miometrio, la pared muscular del útero, puede modificar su misma masa y las propiedades celulares en el embarazo y también en los tumores como el leiomioma y el leiomiosarcoma. El leiomioma, dicho también fibroma, es un tumor benigno del útero y se considera como  una de las causas más frecuentes de infertilità en el período reproductivo femenino. El leiomiosarcoma, en cambio, es un tumor maligno y agresivo de la musculatura lisa uterina. La presente revisión discute las características generales del leiomioma y el leiomiosarcoma y los relativos tratamientos clínicos actualmente usados y además describe las características del miometrio normal en el embarazo.  The myometrium, the muscular wall of the uterus, can modify its mass and cellular properties in pregnancy as well as in tumor conditions such as leiomyoma and leiomyosarcoma. Leiomyomas, also known as fibroids, are benign tumors of the uterus, considered to be one of the most frequent causes of infertility in reproductive years of women. Leiomyosarcomas in turn, are rare aggressive malignant uterine smooth-muscle tumors. The present review is discussing the general features of leiomyoma and leiomyosarcoma with their current treatments and also discussing the characteristics of normal pregnant myometrium and compare with leiomyoma.

New Detection and Treatment for Chlamydia Psittaci: A Case Report

2020 ◽  
Author(s):  
Xiaojing Wu ◽  
Yang Li ◽  
Yingying Feng ◽  
Min Li ◽  
Ye Tian ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Left Lung ◽  
Severe Pneumonia ◽  
Lavage Fluid ◽  
Chlamydia Psittaci ◽  
Premature Delivery ◽  
Correct Treatment ◽  
Case Presentation ◽  
Paired Serum ◽  
Next Generation Sequencing Ngs

Abstract Background: The presentation of psittacosis can vary from subclinical infection to fatal pneumonia with a high mortality rate. Chlamydia psittaci infection during pregnancy is rare and might result in placental involvement, premature delivery or miscarriage. Herein, we report a case of severe pneumonia in a pregnant woman caused by C. psittaci.Case presentation: A 27-year-old female with a pregnancy at 22 weeks was admitted with hyperpyrexia, dry cough and dyspnea. Laboratory tests showed increased white blood cell count and slightly-elevated procalcitonin. Chest computed tomography scan revealed consolidation in the lingual and inferior lobe of the left lung. She suffered rapidly progressing respiratory failure and required mechanical ventilation and extracorporeal membrane oxygenation (ECMO). Her sample of bronchoalveolar lavage fluid (BALF) was collected, from which C. psittaci was detected using next-generation sequencing (NGS). The pathogen was further confirmed by polymerase chain reaction (PCR) with the primers specific for the microorganism. Moreover, paired serum tests showed elevated C. psittaci group titer in both IgG and IgM. She was treated with azithromycin and tigecycline. After 24-day hospitalization, the patient was clinically well and discharged home.Conclusion: We report a case of severe pneumonia in a pregnant woman caused by C. psittaci, which diagnosed by NGS, and was cured without adverse effects on infant with tigecycline. The introduction of NGS and other effective assays might increase the detection rate. C. psittaci infection in pregnant women is very rare, but critical. Early diagnosis and correct treatment may save the mother and fetus. New tetracycline agent, tigecycline, may also be an effective alternative and should be further evaluated in psittacosis.

scholarly journals COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report

2021 ◽  
Author(s):  
Nadine El Kassis ◽  
Wael Abdallah ◽  
Rim Abou Chakra ◽  
Wissam Arab ◽  
Serge Sassine ◽  
...  
Keyword(s):  
Case Report ◽  
Pregnant Woman ◽  
Cesarean Section ◽  
Protective Effect ◽  
Passive Immunization ◽  
Prior History ◽  
Case Presentation ◽  
Maternal Vaccination ◽  
History Of ◽  
In Pregnancy

Aim: Evaluating the newborn passive immunization after maternal vaccination against SARS-COV-2. Case presentation: We present the case of a pregnant woman, with no prior history of COVID-19 infection, who got her second dose of mRNA vaccine against SARS-COV-2, 3 days before the start of her spontaneous labor. She was delivered by cesarean section after dynamical dystocia. Placental cord blood was retrieved immediately and sent to evaluate the titers of COVID-19 antibodies. Vaccine-generated antibodies were present in the umbilical cord with IgG spike >100 AU/ml. Conclusion: By reviewing the literature, vaccination seems to give hope about the potential protective effect of the maternal vaccination on her baby. Thus, pregnant women deserve a priority in the COVID-19 vaccination program.

scholarly journals Spontaneous Pregnancy following Treatment of Symptomatic Uterine Myomatosis with Ulipristal Acetate without Surgery

2021 ◽  
Vol 5 (3) ◽  
pp. 01-05
Author(s):  
Vicente Spinoso Cruz ◽  
Marta Colechá Morales ◽  
Ligia Gil Melgosa ◽  
Aida Revuelta Lopez
Keyword(s):  
Uterine Fibroids ◽  
Reproductive Age ◽  
Fertility Treatment ◽  
Benign Tumors ◽  
Women Of Reproductive Age ◽  
Ulipristal Acetate ◽  
Uterine Myomas ◽  
Spontaneous Pregnancy ◽  
Future Fertility ◽  
Effective Option

Uterine fibroids are the most frequent gynaecological benign tumors in women of reproductive age and can cause infertility. Their treatment may be medical, surgical or a combination of both, but they may compromise future fertility in patients in which their wish to conceive has not yet been fulfilled. In this report we present two patients with symptomatic uterine myomas and who wanted to preserve their fertility. Treatment with one or two 12-week courses of 5 mg of ulipristal acetate was prescribed. A decrease in the size of the fibroids was observed, along with adequate control of the symptoms. Spontaneous pregnancies led to two live births without significant complications. Treatment with Ulipristal Acetate may be an effective option to take into account in the management of patients with symptomatic uterine fibroids who refuse surgery or in those in which it is contraindicated and who wish to preserve their fertility.

scholarly journals Huge Cystadenocarcinoma of the Ovary Disguising as Degenerating Uterine Fibroid in Pregnancy: Case Report and Literature Review

2021 ◽  
Author(s):  
Adedapo Ande ◽  
Maradona Isikhuemen ◽  
Weyinmi Kubeyinje ◽  
Michael Ezeanochie
Keyword(s):  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Abdominal Distension ◽  
Case Presentation ◽  
Serous Cystadenocarcinoma ◽  
Index Pregnancy ◽  
Ovarian Tumours ◽  
Adenocarcinoma Of The Ovary ◽  
High Index Of Suspicion ◽  
In Pregnancy

Abstract Background: Ovarian malignancy is rare in pregnancy and constitutes 3 – 6% of all ovarian tumours associated with pregnancy. It is usually asymptomatic, detected during routine antenatal ultrasound scan. Treatment is mainly surgical. The aim of this report is to share our experience in the management of a referred case of papillary serous cystadenocarcinoma of the ovary disguising as degenerating uterine fibroid in pregnancy. The diagnostic challenges and treatment are highlighted with a view to improving care in our setting.Case presentation: A 29 year old gravida 2 para 1 with one living child was referred to our unit at 25 weeks gestation with complaint of progressive painful abdominal distension with dyspnoea noticed in the index pregnancy. Ultrasound scans were suggestive of uterine fibroid in pregnancy with degenerative changes for which she had conservative management. Due to worsening symptoms, she had laparotomy and a huge ovarian mass was removed alongside the affected ovary. Histology confirmed Serous Papillary Cyst Adenocarcinoma of the ovary. She is doing well on adjuvant chemotherapy. Conclusion: A high index of suspicion for ovarian malignancies in pregnancy, coupled with complementing MRI (when available) with ultrasound to differentiate degenerating uterine fibroids is suggested/recommended.

Hypocalcemia After Thyroidectomy and Parathyroidectomy in a Pregnant Woman

Endocrinology ◽  
2020 ◽  
Vol 161 (7) ◽  
Author(s):  
Benjamin Lebrun ◽  
Christophe De Block ◽  
Yves Jacquemyn
Keyword(s):  
Pregnant Woman ◽  
Fetal Death ◽  
Perinatal Death ◽  
Serum Levels ◽  
Premature Delivery ◽  
Normal Range ◽  
Search Terms ◽  
Time Period ◽  
In Pregnancy

Abstract Hypoparathyroidism during pregnancy is a very rare endocrine disorder. The majority of cases are postsurgical (75%). Managing pregnant or nursing women with hypoparathyroidism is challenging due to complications arising from either under- or overtreatment, including premature delivery or fetal death, abortion, stillbirth, perinatal death, and neonatal tetany. Specific adaptations are needed within each time period to meet the fetal, neonatal, and maternal calcium requirements. A systematic search was performed on PubMed using the search terms “pregnancy” and “hypoparathyroidism.” Included were articles published in English between January 1, 1966, and January 1, 2018. We provide an overview of all published cases (n = 43) of hypoparathyroidism in pregnancy, including a case report of a 29-year-old pregnant woman who underwent a total thyroidectomy before her current pregnancy because of a therapy-resistantant Graves’ disease. The procedure was complicated by postsurgical hypoparathyroidism. She carried out the pregnancy to term with minor complaints of paresthesia and muscle cramps. Furthermore, we discuss treatment, complications, and follow-up of hypoparathyroidism in pregnancy. Treatment of hypoparathyroidism in pregnancy should still be individualized, depending on the patient’s complaints and serum levels of calcium, which should be maintained in the lower normal range of 2.15 to 2.55 mmol/l, according to the literature. We recommend monitoring calcium levels every 3 to 4 weeks throughout the pregnancy, within 1 week postpartum, and monthly during lactation to ensure normocalcemia.

scholarly journals Physiopathology and Management of Uterine Fibroids

2020 ◽  
Author(s):  
Joel Noutakdie Tochie ◽  
Therese Gaelle Badjand ◽  
Gregory Ayissi ◽  
Julius Sama Dohbit
Keyword(s):  
Urinary Incontinence ◽  
Pregnant Woman ◽  
Menstrual Cycle ◽  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Reproductive Age ◽  
Heavy Menstrual Bleeding ◽  
Spontaneous Abortions ◽  
Red Degeneration ◽  
In Pregnancy

Uterine fibroid is the most encountered benign tumour in women of reproductive age. It causes spontaneous abortions, missed abortions, painful red degeneration or infarction of the fibroids, abnormal foetal presentation, obstructed labour, and an increased likelihood of premature deliveries, caesarean deliveries, postpartum haemorrhage in pregnancy, whereas, in the non-pregnant women it is associated an irregular menstrual cycle sometimes associated with heavy menstrual bleeding, infertility, constipation, urinary incontinence, and leiosarcoma transformation. Till date is pathophysiology and management both in the non-pregnant and pregnant woman have not been well described. In this chapter, we present contemporary evidence to help elucidate this enigma.

scholarly journals Pulmonary blastoma in a pregnant woman: a case report and brief review of the literature

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Michał P. Budzik ◽  
Grzegorz Panek ◽  
Małgorzata Bińkowska ◽  
Beata Osuch ◽  
Ewa Borkowska ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Poor Prognosis ◽  
Unusual Case ◽  
Rapid Diagnosis ◽  
Pulmonary Blastoma ◽  
Review Of The Literature ◽  
Embryonic Lung ◽  
Case Presentation ◽  
Lung Tumours ◽  
In Pregnancy

Abstract Background Pulmonary blastoma (PB) comprises a rare heterogeneous group of lung tumours typically containing immature epithelial and mesenchymal structures that imitate the embryonic lung tissue and extremely rarely occurs during pregnancy. Although cough and haemoptysis are the most common PB symptoms, they usually indicate other serious pregnancy-related complications. Case presentation The article presents the unusual case of a 22-year-old pregnant woman diagnosed with PB during pregnancy. Conclusions PB is characterized by poor prognosis and patients’ outcome relies on a rapid diagnosis. Surgery remains the most common and effective treatment. Due to the extreme rarity, the literature contains only single mentions of PB in pregnancy, thus its impact on the course of pregnancy and the developing fetus remains unknown.

An adrenocortical oncocytoma with unusual mitochondrial inclusions and cytoplasmic crystals

1994 ◽  
Vol 52 ◽  
pp. 250-251
Author(s):  
W.T. Gunning ◽  
G.D. Haselhuhn ◽  
E.R. Phillips ◽  
S.H. Selman
Keyword(s):  
Adrenal Gland ◽  
Salivary Glands ◽  
Mitotic Activity ◽  
Diagnostic Criteria ◽  
Vascular Invasion ◽  
Benign Neoplasm ◽  
Benign Tumors ◽  
Nuclear Morphology ◽  
Case Presentation ◽  
Microscopic Evidence

Within the last few years, adrenal cortical tumors with features concordant with the diagnostic criteria attributed to oncocytomas have been reported. To date, only nine reported cases exist in the literature. This report is the tenth case presentation of a presumptively benign neoplasm of the adrenal gland with a rare differentiation. Oncocytomas are well recognized benign tumors of the thyroid, parathyroid, and salivary glands and of the kidney. Other organs also give rise to these types of tumors, however with less frequency than the former sites. The characteristics generally used to classify a tumor as an oncocytoma include the following criteria: the tumor is 1) usually a solitary circumscribed mass with no gross nor microscopic evidence of metastasis (no tissue nor vascular invasion), 2) fairly bland in terms of mitotic activity and nuclear morphology, and 3) composed of large eosinophillic cells in which the cytoplasm is packed full of mitochondria (Figure 1).

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