The probable mechanism of reduced androgen level in COVID-19 patients

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Mohammad Rafi Khezri ◽  
Morteza Ghasemnejad-Berenji ◽  
Negin Mahboubi
Keyword(s):  
Health Care Systems ◽  
Pulmonary Complications ◽  
Probable Mechanism ◽  
The Other ◽  
Androgen Level ◽  
The World ◽  
Care Systems ◽  
Cellular Pathways ◽  
Androgen Levels ◽  
Expression And Activity

Abstract COVID-19, caused by the SARS-CoV-2, has challenged the health care systems of the world. Although the pulmonary complications of the infection have received extensive attention, addressing the other complications (e.g., changes in androgen levels) could further provide a more efficient understanding of the disease, which might aid in combating it. Since the association between androgens and the expression and activity of SARS-CoV-2 receptors has been proven and anti-androgen-based therapies have been considered in this regard, addressing various aspects of androgen level changes can be constructive. The present paper examines the possible mechanisms of changes in androgen levels by the virus. It seems that the infection of the gonads by the SARS-CoV-2 could reduce the androgen levels by affecting different cellular pathways.

scholarly journals Community system of social support

2017 ◽  
Vol 127 (1) ◽  
pp. 37-40
Author(s):  
Krzysztof Włoch ◽  
Janusz Jaroszyński ◽  
Ewa Warchoł-Sławińska ◽  
Anna Jurek ◽  
Bartłomiej Drop ◽  
...  
Keyword(s):  
Social Support ◽  
Health Care ◽  
Health Care Systems ◽  
Family Doctors ◽  
Community System ◽  
Modern Health Care ◽  
Number Of Patients ◽  
The World ◽  
Care Systems ◽  
Is Evaluation

Abstract Community System of Social Support is the basis of modern health care systems not only in Poland but all over the world in the prophylaxis-treatment-rehabilitation procedure. In Poland, family doctors, commune councils and territorial self-governments are involved in it. Family doctors perform a substantial function, whereas commune councils and territorial self-governments an administrative one. The principle of the system work is evaluation of its benefits. Its aim is the reduction of the number of patients who abuse alcohol and those who abuse alcohol despite treatment.

scholarly journals Practical Considerations for Treating Patients With Cancer in the COVID-19 Pandemic

2020 ◽  
Vol 16 (8) ◽  
pp. 467-482 ◽  
Author(s):  
Eva Segelov ◽  
Craig Underhill ◽  
Hans Prenen ◽  
Christos Karapetis ◽  
Christopher Jackson ◽  
...  
Keyword(s):  
Conventional Treatment ◽  
Health Care Systems ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Diverse Group ◽  
Patients With Cancer ◽  
Medical Oncologists ◽  
The World ◽  
Prevalent Disease ◽  
Care Systems

Cancer has become a prevalent disease, affecting millions of new patients globally each year. The COVID-19 pandemic is having far-reaching impacts around the world, causing substantial disruptions to health and health care systems that are likely to last for a prolonged period. Early data have suggested that having cancer is a significant risk factor for mortality from severe COVID-19. A diverse group of medical oncologists met to formulate detailed practical advice on systemic anticancer treatments during this crisis. In the context of broad principles, issues including risks of treatment, principles of prioritizing resources, treatment of elderly patients, and psychosocial impact are discussed. Detailed treatment advice and options are given at a tumor stream level. We must maintain care for patients with cancer as best we can and recognize that COVID-19 poses a significant competing risk for death that changes conventional treatment paradigms.

An Occupational Therapy Course on Community Practice

1995 ◽  
Vol 62 (2) ◽  
pp. 76-81 ◽  
Author(s):  
Constance Vanier ◽  
Michèle Hébert
Keyword(s):  
Health Care ◽  
Occupational Therapy ◽  
Health Care Systems ◽  
Skill Training ◽  
Community Services ◽  
The Other ◽  
Community Practice ◽  
Community Based ◽  
Care Systems ◽  
The University

This article outlines a course on occupational therapy community practice offered at the University of Ottawa and discusses its assets and limitations in terms of preparing students for the shift to community-based health services. The shift to community services in the health care systems of Ontario and Québec is described. Then the curricular components needed to prepare students for community practice are summarized. Finally, the community practice course at the University of Ottawa including its goal, objectives, class topics and evaluations is outlined. The strength of the community practice course described is that it includes many of the curricular components needed for community practice. On the other hand, limitations include the lack of skill training in some areas, its place in the last year of the programme, and its optional nature. Changes planned for the course and other recommendations for curricula are also discussed.

scholarly journals Contemporary rehabilitation at cancer centres

2014 ◽  
Vol 83 (2) ◽  
pp. 156-160
Author(s):  
Katarzyna Hojan
Keyword(s):  
Health Care Systems ◽  
Review Article ◽  
Cancer Rehabilitation ◽  
Continuous Part ◽  
Rehabilitation Care ◽  
Cancer Services ◽  
The World ◽  
Care Systems ◽  
Professional Resources ◽  
Extent Of Disease

Aim. Cancer rehabilitation is an important, but often underutilized treatment in the comprehensive care of the cancer patient. The lack of appropriate referral by physicians unfamiliar with the concept of rehabilitation was identified as primary barriers to optimal delivery of rehabilitation care. Therefore, the aim of this paper is to describe the current situation in the world of science of cancer rehabilitation and to describe availability of professional resources in the selected countries in the world. Material and methods. This paper is a review article to describe rehabilitation models in cancer services for patients in selected cases in the world.Results. Rehabilitation should be applied in various settings, depending on the level of disability, extent of disease, medical acuity level of the patient, and available services. However, the rehabilitation systems in the world differ depending on the various social security and health-care systems, but they are largely based on a similar, multidimensional and multidisciplinary understanding of cancer rehabilitation. Conclusions. On the basis of description of the bio-psycho-social models, it can be seen that rehabilitation must be an integral and continuous part of all cancer care. There is strong evidence that rehabilitation is a well-tolerated and safe adjunct therapy that can mitigate several common treatment-related side effects among cancer patients.

scholarly journals An Osteopathic Perspective on COVID-19: Is There a Missing Link to Treatment?

2020 ◽  
Vol 30 (3) ◽  
pp. 7-14
Author(s):  
Richard Chmielewski
Keyword(s):  
Lymphatic System ◽  
Health Care Systems ◽  
Developed Countries ◽  
Modern Medicine ◽  
Pulmonary Complications ◽  
Missing Link ◽  
The Public ◽  
Technological Interventions ◽  
Care Facilities ◽  
Care Systems

Abstract As the COVID-19 pandemic progressed across the globe, clinical reports and autopsies on patient deaths proved that the pulmonary complications were the result of an acute respiratory distress syndrome caused by an excessive inflammatory response; a cytokine storm. Through literature research and review it has become apparent to the author that the lymphatic system is a vital, somewhat overlooked, missing link in the treatment of COVID-19 pulmonary infection. The major challenges the whole world is facing now have been a shortage of supplies such as PPE, or personal protective equipment, and intensive care facilities to treat the overwhelming numbers of COVID-19 cases, in under-developed countries as well as developed countries. Osteopathic manipulative medicine (OMM) and osteopathic manipulative treatment (OMT) have been proven, for over a century, to be very effective in the treatment of pulmonary diseases and previous pandemics. Osteopathic professionals must challenge the present paradigm of modern medicine which, only too often, relies less on the body’s own capacity to regulate itself, to compensate, and to heal, and more on outside intervention such as medications and vaccinations. Osteopathic physicians are needed to step forward and discuss, explain, teach and train the importance of the lymphatic system as a major component of the circulatory as well as the immune system which plays a vital, pivotal, role in fighting diseases such as the COVID-19 coronavirus. A “viral infection protocol” (VIP), as discussed in this article, needs to be promoted as a mainstream adjunct, along with all of the other modalities of modern medicine, to health professionals and the public, in the event that the health care systems are overwhelmed. The VIP treatment is easy to train and to certify practitioners, with proven results in other pulmonary infections and epidemics. It may prove invaluable in preventing clinical deterioration of masses of patients, who then would require more expensive, less available, and more dangerous technological interventions.

scholarly journals Back into Modernity? COVID-19 Returns Nation-State to Its Original Nature

2020 ◽  
Vol 11 (1) ◽  
pp. 11-26
Author(s):  
N. Yu. Silaev ◽  
N. P. Protsenko
Keyword(s):  
Historical Perspective ◽  
International System ◽  
Health Care Systems ◽  
Current Crisis ◽  
Market Mechanisms ◽  
The World ◽  
Collateral Effect ◽  
Care Systems ◽  
Power Inequality ◽  
State Interventions

From a historical perspective, the curbing of epidemics was the collateral effect of emerging European Modern states. The current COVID-19 pandemic reminds that. It supports the broad international tendency to strengthen state sovereignty, nationalism, and economic protectionism. Meanwhile, in recent decades health care systems around the world have been evolving toward deregulation, use of market mechanisms, and decrease of state interventions, and it was one of the most salient evidence that Modern state is being deconstructed. The current crisis puts forward the prospect that Modern comes back with the following social conflicts, interstate rivalry, and growing power inequality between the international system actors.

scholarly journals Early evidence that social distancing and public health interventions flatten the COVID-19 curve in Italy

2020 ◽  
Author(s):  
Valentina Rotondi ◽  
Liliana Andriano ◽  
Jennifer Beam Dowd ◽  
Melinda C. Mills
Keyword(s):  
Health Care Systems ◽  
Scientific Evidence ◽  
Health Interventions ◽  
Infection Rates ◽  
Public Health Interventions ◽  
Social Distancing ◽  
Early Evidence ◽  
The World ◽  
Care Systems ◽  
Policy Measures

With the world experiencing one of the largest pandemics in one-hundred years, governments and policymakers are looking for scientific evidence to introduce rapid and effective policies. Here we provide evidence from two provinces in Italy with comparable early infection rates but different timing of mitigating policy measures. Lodi prohibited movement on February 23, 2020 and Bergamo 2 weeks later on March 8, before the entire lockdown of Italy on March 11. This comparison provides early evidence that rapid restriction of movement and social distancing measures may slow the transmission of the virus and “flatten the curve”, ultimately reducing pressure on health care systems

scholarly journals Impact of the COVID-19 pandemic on radiologists

2020 ◽  
Vol 72 ◽  
pp. 177-180
Author(s):  
Ganesh Hegde ◽  
Christine Azzopardi ◽  
Patrick Hurley ◽  
Harun Gupta ◽  
Naga Varaprasad Vemuri ◽  
...  
Keyword(s):  
Health Care Systems ◽  
Continuing Professional Development ◽  
Well Being ◽  
Radiology Workflow ◽  
Protective Equipment ◽  
Ability To Work ◽  
Innovative Solutions ◽  
The World ◽  
Care Systems ◽  
The Impact

COVID-19 pandemic is one of the biggest crises faced by health-care systems in the recent times. The aim of this study was to assess the impact of the COVID-19 pandemic on radiology workflow, working pattern, training and continuing professional development (CPD) activities, as well as personal well-being of the radiologists during the pandemic. Material and Methods: Questionnaire designed to gather the opinions regarding the impact of the COVID-19 pandemic was distributed to radiologists throughout the world in electronic format. Anonymized responses were obtained and analyzed. Two hundred radiologists, working in 17 different countries, responded to our questionnaire. Majority of the respondents were from India (72.8%) and 70% of the them were in the age group of 25–45 years. About 80% of respondents felt that they were well protected or moderately well protected in terms of the personal protective equipment (PPE), however, most of them felt that the use of PPE had affected their ability to work. Similar number of radiologists felt that there was significant reduction in the radiology workload. More than half of the respondents felt that their working patterns were altered by the pandemic with drastic impact on teaching, CPD activities, and personal well-being. COVID-19 pandemic has had profound impact on the radiologists all over the world. Learning from the experiences of the first wave should be used to provide innovative solutions to some of the challenges posed to provide better radiology services, training, and improve the well-being of radiologists if we encounter a similar situation in the future. COVID-19 pandemic had significant impact on radiologists. Radiologists felt that they were well or moderately well protected with PPEs; however, PPEs affected their ability to work. Radiology workflow was significantly reduced in the pandemic with more radiologists working from home. COVID-19 pandemic had deleterious effect on radiologist’s well-being, education, and CPD activities.

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