Life sciences and mass spectrometry: some personal reflections

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Jasna Peter-Katalinic

Abstract Molecular analysis of biological systems by mass spectrometry was in focus of technological developments in the second half of the 20th century, in which the issues of chemical identification of high molecular diversity by biophysical instrumental methods appeared as a mission impossible. By developing dialogs between researchers dealing with life sciences and medicine on one side and technology developers on the other, new horizons toward deciphering, identifying and quantifying of complex systems became a reality. Contributions toward this goal can be today considered as pioneering efforts delivered by a number of researchers, including generations of motivated students and associates.

2002 ◽  
Vol 12 (3) ◽  
Author(s):  
Goran Mijic

This essay concentrates on scientific-rationalist discourses entering massively the realm of literature at the beginning of the 20th century. They open new horizons revealing phenomena unknown before on the one side, but they also obscure the world around us providing convenient screen from painful truths on the other. This paper tries to demonstrate how technological discourses move the reader from a highly visual receptive position to a pure cognitive realm of symbolic representations with its own dynamics. The scientific-rationalist discourses produce a new parallel reality, a scientific haze tending to withdraw from visual representation.


Author(s):  
Laura Hengehold

Most studies of Simone de Beauvoir situate her with respect to Hegel and the tradition of 20th-century phenomenology begun by Husserl, Heidegger, and Merleau-Ponty. This book analyzes The Second Sex in light of the concepts of becoming, problematization, and the Other found in Gilles Deleuze. Reading Beauvoir through a Deleuzian lens allows more emphasis to be placed on Beauvoir's early interest in Bergson and Leibniz, and on the individuation of consciousness, a puzzle of continuing interest to both phenomenologists and Deleuzians. By engaging with the philosophical issues in her novels and student diaries, this book rethinks Beauvoir’s focus on recognition in The Second Sex in terms of women’s struggle to individuate themselves despite sexist forms of representation. It shows how specific forms of women’s “lived experience” can be understood as the result of habits conforming to and resisting this sexist “sense.” Later feminists put forward important criticisms regarding Beauvoir’s claims not to be a philosopher, as well as the value of sexual difference and the supposedly Eurocentric universalism of her thought. Deleuzians, on the other hand, might well object to her ideas about recognition. This book attempts to address those criticisms, while challenging the historicist assumptions behind many efforts to establish Beauvoir’s significance as a philosopher and feminist thinker. As a result, readers can establish a productive relationship between Beauvoir’s “problems” and those of women around the world who read her work under very different circumstances.


2019 ◽  
Vol 64 (1) ◽  
pp. 27-36
Author(s):  
А. Г. БОДРОВА

The paper considers travelogues of Yugoslav female writers Alma Karlin, Jelena Dimitrijević, Isidora Sekulić, Marica Gregorič Stepančič, Marica Strnad, Luiza Pesjak. These texts created in the first half of the 20th century in Serbian, Slovenian and German are on the periphery of the literary field and, with rare exceptions, do not belong to the canon. The most famous of these authors are Sekulić from Serbia and the German-speaking writer Karlin from Slovenia. Recently, the work of Dimitrijević has also become an object of attention of researchers. Other travelogues writers are almost forgotten. Identity problems, especially national ones, are a constant component of the travelogue genre. During a journey, the author directs his attention to “other / alien” peoples and cultures that can be called foreign to the perceiving consciousness. However, when one perceives the “other”, one inevitably turns to one's “own”, one's own identity. The concept of “own - other / alien”, on which the dialogical philosophy is based (M. Buber, G. Marcel, M. Bakhtin, E. Levinas), implies an understanding of the cultural “own” against the background of the “alien” and at the same time culturally “alien” on the background of “own”. Women's travel has a special status in culture. Even in the first half of the 20th century the woman was given space at home. Going on a journey, especially unaccompanied, was at least unusual for a woman. According to Simone de Beauvoir, a woman in society is “different / other”. Therefore, women's travelogues can be defined as the look of the “other” on the “other / alien”. In this paper, particular attention is paid to the interrelationship of gender, national identities and their conditioning with a cultural and historical context. At the beginning of the 20th century in the Balkans, national identity continues actively to develop and the process of women's emancipation is intensifying. Therefore, the combination of gender and national issues for Yugoslavian female travelogues of this period is especially relevant. Dimitrijević's travelogue Seven Seas and Three Oceans demonstrates this relationship most vividly: “We Serbian women are no less patriotic than Egyptian women... Haven't Serbian women most of the merit that the big Yugoslavia originated from small Serbia?” As a result of this study, the specificity of the national and gender identity constructs in the first half of the 20th century in the analyzed texts is revealed. For this period one can note, on the one hand, the preservation of national and gender boundaries, often supported by stereotypes, on the other hand, there are obvious tendencies towards the erosion of the established gender and national constructs, the mobility of models of gender and national identification as well, largely due to the sociohistorical processes of the time.


TAJDID ◽  
2018 ◽  
Vol 25 (2) ◽  
pp. 119
Author(s):  
Ahmad Tholabi Kharlie

Tafsîr al-Manar is one of the most popular exegesis of the Qur`anic studies. Al-Manar magazine, which contains this interpretation periodically, namely in the early 20th century, is widespread throughout the Islamic world and has an important role in enlightening thoughts and religious counseling. The influence of Sheikh Muhammad Abduh, along with his student, Sayyid Muhammad Rasyîd Ridhâ, on the development of religious thought in the Islamic world, thus, cannot be underestimated.This article is a result of a previous study of the Qur’an exegesis method of the two prominent Muslim scholars, Muhammad Abduh and Muhammad Rashid Ridha. The study reveals two main conclusions, they are (1) personally both Muhammad Abduh and Muhammad Rashid Ridha are independent who have extensive, well-known, and versatile insight and knowledge, have personality traits that are steady, honest, brave, passionate, intelligent, determined, and a number of other advantages, like other leading commentator (2) Al-manâr book, with its superiorities, is well recognized as a monumental work that broadly contributes to the development of Islamic thought, particularly in modern exegesis field. In regard to exegesis of Qur’anic legal verses, though it is not a special legal book, Al-manâr is able to explain deeply and comprehensively the Qur’anic legal verses just like the other legal exegesis works.


Author(s):  
Dubey Somil

The word Malahara or Malhama is derived from unani system of medicine. Yogaratnakara mentioned this first by the name of Malahara Kalpana. It derives its name as it removes Mala (residue etc.) from Vrana (wounds), Vidradhi (abscess) etc. This is similar to ointments in modern pharmaceutics. Malahara Kalpana is the ointment preparation which has Siktha Taila (bees wax and oil mixture) or Ghrita, as the basic constituent. The other ingredients may include herbal, metal, or mineral contents depending upon the usage. Malahara has a property like Snehana (oelation), cleansing, Ropana (healing), Lekhana (scaraping), and Varnya (beautifying), depending on the drugs used in the preparation. Rasa Tarangani a Rasa Shastra treatise of 20th century by Acharya Sadananda Sharma has enumerated various types of Malahara Kalpana taking mainly Siktha Taila as a base. Though this Kalpana holds firm roots in treating diseases the mention and explanation of this particular topic is scattered in this treatise. Hence the present article is an attempt to elucidate and unfold the Malahara Kalpana of Rasatarangani.


Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2335
Author(s):  
Gabriella Pinto ◽  
Sabrina De Pascale ◽  
Maria Aponte ◽  
Andrea Scaloni ◽  
Francesco Addeo ◽  
...  

Plant polyphenols have beneficial antioxidant effects on human health; practices aimed at preserving their content in foods and/or reusing food by-products are encouraged. The impact of the traditional practice of the water curing procedure of chestnuts, which prevents insect/mould damage during storage, was studied to assess the release of polyphenols from the fruit. Metabolites extracted from pericarp and integument tissues or released in the medium from the water curing process were analyzed by matrix-assisted laser desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS) and electrospray-quadrupole-time of flight-mass spectrometry (ESI-qTOF-MS). This identified: (i) condensed and hydrolyzable tannins made of (epi)catechin (procyanidins) and acid ellagic units in pericarp tissues; (ii) polyphenols made of gallocatechin and catechin units condensed with gallate (prodelphinidins) in integument counterparts; (iii) metabolites resembling those reported above in the wastewater from the chestnut curing process. Comparative experiments were also performed on aqueous media recovered from fruits treated with processes involving: (i) tap water; (ii) tap water containing an antifungal Lb. pentosus strain; (iii) wastewater from a previous curing treatment. These analyses indicated that the former treatment determines a 6–7-fold higher release of polyphenols in the curing water with respect to the other ones. This event has a negative impact on the luster of treated fruits but qualifies the corresponding wastes as a source of antioxidants. Such a phenomenon does not occur in wastewater from the other curing processes, where the release of polyphenols was reduced, thus preserving the chestnut’s appearance. Polyphenol profiling measurements demonstrated that bacterial presence in water hampered the release of pericarp metabolites. This study provides a rationale to traditional processing practices on fruit appearance and qualifies the corresponding wastes as a source of bioactive compounds for other nutraceutical applications.


Proceedings ◽  
2020 ◽  
Vol 47 (1) ◽  
pp. 55
Author(s):  
Shan Zhang

By applying the concept of natural science to the study of music, on the one hand, we can understand the structure of music macroscopically, on the other, we can reflect on the history of music to a certain extent. Throughout the history of western music, from the classical period to the 20th century, music seems to have gone from order to disorder, but it is still orderly if analyzed carefully. Using the concept of complex information systems can give a good answer in the essence.


Radiocarbon ◽  
2021 ◽  
pp. 1-7
Author(s):  
Corina Solís ◽  
Efraín Chávez ◽  
Arcadio Huerta ◽  
María Esther Ortiz ◽  
Alberto Alcántara ◽  
...  

ABSTRACT Augusto Moreno is credited with establishing the first radiocarbon (14C) laboratory in Mexico in the 1950s, however, 14C measurement with the accelerator mass spectrometry (AMS) technique was not achieved in our country until 2003. Douglas Donahue from the University of Arizona, a pioneer in using AMS for 14C dating, participated in that experiment; then, the idea of establishing a 14C AMS laboratory evolved into a feasible project. This was finally reached in 2013, thanks to the technological developments in AMS and sample preparation with automated equipment, and the backing and support of the National Autonomous University of Mexico and the National Council for Science and Technology. The Mexican AMS Laboratory, LEMA, with a compact 1 MV system from High Voltage Engineering Europa, and its sample preparation laboratories with IonPlus automated graphitization equipment, is now a reality.


Author(s):  
Xing Wang ◽  
Henk G. Jansen ◽  
Haico Duin ◽  
Harro A. J. Meijer

AbstractThere are two officially approved methods for stable isotope analysis for wine authentication. One describes δ18O measurements of the wine water using Isotope Ratio Mass Spectrometry (IRMS), and the other one uses Deuterium-Nuclear Magnetic Resonance (2H-NMR) to measure the deuterium of the wine ethanol. Recently, off-axis integrated cavity output (laser) spectroscopy (OA-ICOS) has become an easier alternative to quantify wine water isotopes, thanks to the spectral contaminant identifier (SCI). We utilized an OA-ICOS analyser with SCI to measure the δ18O and δ2H of water in 27 wine samples without any pre-treatment. The OA-ICOS results reveal a wealth of information about the growth conditions of the wines, which shows the advantages to extend the official δ18O wine water method by δ2H that is obtained easily from OA-ICOS. We also performed high-temperature pyrolysis and chromium reduction combined with IRMS measurements to illustrate the “whole wine” isotope ratios. The δ18O results of OA-ICOS and IRMS show non-significant differences, but the δ2H results of both methods differ much more. As the δ2H difference between these two methods is mainly caused by ethanol, we investigated the possibility to deduce deuterium of wine ethanol from this difference. The results present large uncertainties and deviate from the obtained 2H-NMR results. The deviation is caused by the other constituents in the wine, and the uncertainty is due to the limited precision of the SCI-based correction, which need to improve to obtain the 2H values of ethanol as alternative for the 2H-NMR method.


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