Die Bundeswehr als Zauberlehrling der Politik? Der ISAF-Einsatz und das Provincial Reconstruction Team Kunduz 2003 bis 2012

2013 ◽  
Vol 72 (2) ◽  
pp. 317-352 ◽  
Author(s):  
Bernhard Chiari
Keyword(s):  
Security Policy ◽  
Military History ◽  
Lessons Learned ◽  
Peace Building ◽  
The Balkans ◽  
Supply Logistics ◽  
Movement Field ◽  
Official Sources ◽  
Insight Into ◽  
Made In

Abstract Using the example of the Provincial Reconstruction Team (PRT) in Kunduz, the paper explores the capabilities of military history to contribute to current debates on the change of German Military- and Security policy by providing studies on the »army on operations«. Based on official sources, which the German MoD made generally accessible for researchers of the MGFA/ZMSBw in 2011, the author analyzes the Bundeswehr’s presence in Kunduz between 2003 and 2012. He critically assesses, to what extent the Bundeswehr - aside from supply, logistics and force protection - actually did produce security and stability in Afghanistan. Documents and interviews give an insight into how conceptions of conflict resolution and Peace Building, based on lessons learned on the Balkans, interacted with the experiences made in Northern Afghanistan, but failed to prevent the spread of the Taliban-movement. Field reports, war diaries and other sources reflect the complex interdependency between the troops in the field, higher ISAF commands, and the responsible military staffs in Germany.

scholarly journals Estimating Choice Models to Quantify the Effect of Herding on the Decision to Evacuate: Application of a Serious Gaming Experimental Setup

2018 ◽  
Vol 2672 (1) ◽  
pp. 161-170 ◽  
Author(s):  
Mignon Van den Berg ◽  
Rob van Nes ◽  
Serge Hoogendoorn
Keyword(s):  
Emergency Management ◽  
Natural Disaster ◽  
Choice Models ◽  
Experimental Setup ◽  
Management Personnel ◽  
Factors Influencing ◽  
Official Sources ◽  
Source Of Information ◽  
Insight Into ◽  
Made In

Insight into factors influencing the choices people make in case of an evacuation from a natural disaster can help governments and emergency management personnel to manage people in case of such a situation. One of the aspects that influences the choices that people make in such a situation is herding. Since herding has not been quantified, this paper focuses on quantifying the effect of herding on the decision to evacuate by using an experimental setup that is based on the serious game Everscape. Around 400 people participated in 13 experiments with this setup. Choice models were estimated with the data from these experiments by including observable characteristics of herding as an attribute into the utility function. It is concluded that an important step is made in quantifying herding. It is shown that the more people someone sees leaving, the more inclined this person is to leave. Seeing people leave has more impact than seeing people stay. When people have no information from official sources, they tend to use other people as a source of information. In case of a disaster, this might result in following people who make the situation even more dangerous (for themselves and possibly for others as well). The information provided by official sources is therefore essential in managing people in the best possible way in case of a natural disaster.

Experimental Therapeutics

2014 ◽  
Author(s):  
Beth Borowsky ◽  
Cristina Sampaio
Keyword(s):  
Clinical Trials ◽  
Lessons Learned ◽  
Pharmaceutical Companies ◽  
Experimental Therapeutics ◽  
Patient Registries ◽  
Academic Researchers ◽  
History Of ◽  
Insight Into ◽  
Made In

Bringing safe and effective treatments to patients with Huntington’s disease (HD) will require evaluation in properly designed and conducted clinical trials. Such clinical trials will require appropriate tools and practices, including therapeutics, patient registries, biomarkers, endpoints, trial design, and analysis tools. This chapter provides insight into the advances being made in each of these areas and highlights the challenges remaining. Lessons learned from prior HD trials as well as from trials in other neurodegenerative diseases affect our view of future HD clinical development. With much interest from both pharmaceutical companies and academic researchers, this final chapter of the book actually opens a new chapter in the history of HD drug development.

Past, Present, and Future of Measles, Mumps, and Rubella Virus Vaccines

PEDIATRICS ◽  
1992 ◽  
Vol 90 (1) ◽  
pp. 149-153
Author(s):  
Maurice R. Hilleman
Keyword(s):  
Measles Virus ◽  
Lessons Learned ◽  
Measles Vaccine ◽  
Rubella Vaccine ◽  
The Past ◽  
Viral Vaccine ◽  
The World ◽  
Insight Into ◽  
Festive Occasion ◽  
Made In

It is a real pleasure for me to speak on this memorable occasion. Dr Saul Krugman is now entering his ninth decade while enjoying the world status of senior statesman! Saul and I have collaborated often during the last three of these decades. In the studies of new vaccines in our laboratories, our first clinical probes were made in cooperative studies with the late Dr Joseph Stokes and his colleagues and successors at the Children's Hospital of Philadelphia. Following such initial phase, Dr Krugman received the vaccines for expanded clinical studies. Hence, he has been an indispensible clinical partner in most of the new viral vaccine developments in our laboratories during the past 30 years. In discussions with Dr Wade Parks, I was advised that I might speak on any subject I choose. I chose to talk about the measles-mumps-rubella vaccine (M-M-R), a topic that has occupied Dr Krugman for nearly three decades and that is receiving renewed attention in the worlds of pediatrics and public health at the present time. This being a festive occasion, I feel I should keep it light. Therefore, I want to emphasize the science, but also to recount some of the less well-known "behind-the-scenes" activities that led to the creation and birth of M-M-R. There were lessons learned that might provide historic insight into problems that can be avoided in the future. MEASLES Measles vaccine began when the late Dr John Enders and Dr Samuel Katz and their coworkers developed and tested their Edmonston strain of attenuated live measles virus.1

Will Love Tear Us Apart: Adapting the Lyrical to the Ludic

CounterText ◽  
2016 ◽  
Vol 2 (2) ◽  
pp. 217-235
Author(s):  
Gordon Calleja
Keyword(s):  
Design Process ◽  
Game Design ◽  
Digital Games ◽  
Design Decisions ◽  
The Core ◽  
Lyrical Poetry ◽  
Insight Into ◽  
Made In

This paper gives an insight into the design process of a game adaptation of Joy Division's Love Will Tear Us Apart (1980). It outlines the challenges faced in attempting to reconcile the diverging qualities of lyrical poetry and digital games. In so doing, the paper examines the design decisions made in every segment of the game with a particular focus on the tension between the core concerns of the lyrical work being adapted and established tenets of game design.

Radical Subject Acceleration for Gifted Students: One School's Response

2019 ◽  
pp. 29-46
Author(s):  
Kaye Chalwell ◽  
Therese Cumming
Keyword(s):  
Gifted And Talented ◽  
Gifted Students ◽  
Subject Area ◽  
Lessons Learned ◽  
Gifted Student ◽  
Learning Needs ◽  
Mathematically Gifted ◽  
Support Students ◽  
Insight Into

Radical subject acceleration, or moving students through a subject area faster than is typical, including skipping grades, is a widely accepted approach to support students who are gifted and talented. This is done in order to match the student’s cognitive level and learning needs. This case study explored radical subject acceleration for gifted students by focusing on one school’s response to the learning needs of a ten year old mathematically gifted student. It provides insight into the challenges, accommodations and approach to radical subject acceleration in an Australian school. It explored the processes and decisions made to ensure that a gifted student’s learning needs were met and identified salient issues for radical subject acceleration. Lessons learned from this case study may be helpful for schools considering radical acceleration.

scholarly journals H3ABioNet genomic medicine and microbiome data portals hackathon proceedings

Database ◽  
2021 ◽  
Vol 2021 ◽  
Author(s):  
Faisal M Fadlelmola ◽  
Kais Ghedira ◽  
Yosr Hamdi ◽  
Mariem Hanachi ◽  
Fouzia Radouani ◽  
...  
Keyword(s):  
Ethnic Groups ◽  
Genomic Medicine ◽  
Lessons Learned ◽  
Team Work ◽  
Significant Progress ◽  
Team Members ◽  
Pan African ◽  
Scientific Expertise ◽  
Microbiome Data ◽  
Made In

Abstract African genomic medicine and microbiome datasets are usually not well characterized in terms of their origin, making it difficult to find and extract data for specific African ethnic groups or even countries. The Pan-African H3Africa Bioinformatics Network (H3ABioNet) recognized the need for developing data portals for African genomic medicine and African microbiomes to address this and ran a hackathon to initiate their development. The two portals were designed and significant progress was made in their development during the hackathon. All the participants worked in a very synergistic and collaborative atmosphere in order to achieve the hackathon's goals. The participants were divided into content and technical teams and worked over a period of 6 days. In response to one of the survey questions of what the participants liked the most during the hackathon, 55% of the hackathon participants highlighted the familial and friendly atmosphere, the team work and the diversity of team members and their expertise. This paper describes the preparations for the portals hackathon and the interaction between the participants and reflects upon the lessons learned about its impact on successfully developing the two data portals as well as building scientific expertise of younger African researchers. Database URL: The code for developing the two portals was made publicly available in GitHub repositories: [https://github.com/codemeleon/Database; https://github.com/codemeleon/AfricanMicrobiomePortal].

scholarly journals Whither Magnetic Hyperthermia? A Tentative Roadmap

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 706
Author(s):  
Irene Rubia-Rodríguez ◽  
Antonio Santana-Otero ◽  
Simo Spassov ◽  
Etelka Tombácz ◽  
Christer Johansson ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Nanoparticle Synthesis ◽  
Careful Analysis ◽  
Magnetic Hyperthermia ◽  
Lessons Learned ◽  
In Vivo Testing ◽  
Evolution Of Science ◽  
Made In ◽  
Critical Aspects

The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing have been seeking to push the forefront towards some new clinical trials. As many, they did not go at the expected pace. Today, fruitful international cooperation and the wisdom gain after a careful analysis of the lessons learned from seminal clinical trials allow us to have a future with better guarantees for a more definitive takeoff of this genuine nanotherapy against cancer. Deliberately giving prominence to a number of critical aspects, this opinion review offers a blend of state-of-the-art hints and glimpses into the future of the therapy, considering the expected evolution of science and technology behind magnetic hyperthermia.

scholarly journals Deploying triple artemisinin-based combination therapy (TACT) for malaria treatment in Africa: ethical and practical considerations

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Paulina Tindana ◽  
Freek de Haan ◽  
Chanaki Amaratunga ◽  
Mehul Dhorda ◽  
Rob W. van der Pluijm ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Combination Therapy ◽  
Southeast Asia ◽  
Malaria Control ◽  
Lessons Learned ◽  
Line Treatment ◽  
African Continent ◽  
First Line ◽  
First Line Treatment ◽  
Made In

AbstractMalaria remains a major cause of morbidity and mortality in Africa, particularly in children under five years of age. Availability of effective anti-malarial drug treatment is a cornerstone for malaria control and eventual malaria elimination. Artemisinin-based combination therapy (ACT) is worldwide the first-line treatment for uncomplicated falciparum malaria, but the ACT drugs are starting to fail in Southeast Asia because of drug resistance. Resistance to artemisinins and their partner drugs could spread from Southeast Asia to Africa or emerge locally, jeopardizing the progress made in malaria control with the increasing deployment of ACT in Africa. The development of triple artemisinin-based combination therapy (TACT) could contribute to mitigating the risks of artemisinin and partner drug resistance on the African continent. However, there are pertinent ethical and practical issues that ought to be taken into consideration. In this paper, the most important ethical tensions, some implementation practicalities and preliminary thoughts on addressing them are discussed. The discussion draws upon data from randomized clinical studies using TACT combined with ethical principles, published literature and lessons learned from the introduction of artemisinin-based combinations in African markets.

scholarly journals Sex as a Prognostic Factor in Systematic Reviews: Challenges and Lessons Learned

2021 ◽  
Vol 11 (6) ◽  
pp. 441
Author(s):  
Elena Stallings ◽  
Alba Antequera ◽  
Jesús López-Alcalde ◽  
Miguel García-Martín ◽  
Gerard Urrútia ◽  
...  
Keyword(s):  
Prognostic Factor ◽  
Systematic Reviews ◽  
Lessons Learned ◽  
Disease State ◽  
Sex And Gender ◽  
Funding Agencies ◽  
And Gender ◽  
Baseline Factor ◽  
Clinical Domain ◽  
Made In

Sex is a common baseline factor collected in studies that has the potential to be a prognostic factor (PF) in several clinical areas. In recent years, research on sex as a PF has increased; however, this influx of new studies frequently shows conflicting results across the same treatment or disease state. Thus, systematic reviews (SRs) addressing sex as a PF may help us to better understand diseases and further personalize healthcare. We wrote this article to offer insights into the challenges we encountered when conducting SRs on sex as a PF and suggestions on how to overcome these obstacles, regardless of the clinical domain. When carrying out a PF SR with sex as the index factor, it is important to keep in mind the modifications that must be made in various SR stages, such as modifying the PF section of CHARMS-PF, adjusting certain sections of QUIPS and extracting data on the sex and gender terms used throughout the studies. In this paper, we provide an overview of the lessons learned from carrying out our reviews on sex as a PF in different disciplines and now call on researchers, funding agencies and journals to realize the importance of studying sex as a PF.

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