scholarly journals Oleic Acid - Health Benefits and Status in Plasma Phospholipids in the Serbian Population

2019 ◽  
Vol 20 (2) ◽  
pp. 3-8 ◽  
Author(s):  
Aleksandra Arsic ◽  
Ana Stojanovic ◽  
Milena Mikic
Keyword(s):  
Oleic Acid ◽  
Fatty Acid ◽  
Olive Oil ◽  
Chronic Diseases ◽  
Acid Metabolism ◽  
Oil Consumption ◽  
Plasma Phospholipids ◽  
Beneficial Effects ◽  
Acid Status ◽  
Infants And Young Children

Abstract Oleic acid has many beneficial effects on human health. One of the main dietary sources of oleic acid is olive oil. Non-Mediterranean European countries, including Serbia, have low habitual olive oil consumption, but other vegetable oils also contain different amounts of oleic acid. In infants and young children milk is the most important source of fatty acids, including oleic acid. Furthermore, fatty acid composition of plasma phospholipids reflects dietary intake and fatty acid metabolism. In patients with serious chronic diseases fatty acid status is altered independently on the intake. Here we reviewed status of oleic acid in healthy persons as well as in patients with different chronic diseases in Serbia.

scholarly journals Role of Oleic Acid in the Gut-Liver Axis: From Diet to the Regulation of Its Synthesis via Stearoyl-CoA Desaturase 1 (SCD1)

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2283 ◽  
Author(s):  
Elena Piccinin ◽  
Marica Cariello ◽  
Stefania De Santis ◽  
Simon Ducheix ◽  
Carlo Sabbà ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Fatty Acid ◽  
Olive Oil ◽  
Intestinal Inflammation ◽  
Principal Component ◽  
Monounsaturated Fatty Acids ◽  
Beneficial Effects ◽  
Stearoyl Coa Desaturase ◽  
The Impact

The consumption of an olive oil rich diet has been associated with the diminished incidence of cardiovascular disease and cancer. Several studies have attributed these beneficial effects to oleic acid (C18 n-9), the predominant fatty acid principal component of olive oil. Oleic acid is not an essential fatty acid since it can be endogenously synthesized in humans. Stearoyl-CoA desaturase 1 (SCD1) is the enzyme responsible for oleic acid production and, more generally, for the synthesis of monounsaturated fatty acids (MUFA). The saturated to monounsaturated fatty acid ratio affects the regulation of cell growth and differentiation, and alteration in this ratio has been implicated in a variety of diseases, such as liver dysfunction and intestinal inflammation. In this review, we discuss our current understanding of the impact of gene-nutrient interactions in liver and gut diseases, by taking advantage of the role of SCD1 and its product oleic acid in the modulation of different hepatic and intestinal metabolic pathways.

Olive oil consumption, plasma oleic acid, and stroke incidence: The Three-City Study

Neurology ◽  
2011 ◽  
Vol 77 (5) ◽  
pp. 418-425 ◽  
Author(s):  
C. Samieri ◽  
C. Feart ◽  
C. Proust-Lima ◽  
E. Peuchant ◽  
C. Tzourio ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Olive Oil ◽  
Oil Consumption ◽  
Stroke Incidence

scholarly journals The effect of fetal pig size and stage of gestation on tissue fatty acid metabolism and profile

Reproduction ◽  
2005 ◽  
Vol 129 (6) ◽  
pp. 757-763 ◽  
Author(s):  
Christopher J McNeil ◽  
Angela M Finch ◽  
Kenneth R Page ◽  
Steve D Clarke ◽  
Cheryl J Ashworth ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fetal Growth ◽  
Fatty Acid Metabolism ◽  
Fatty Acid Synthase ◽  
Porcine Model ◽  
Acid Metabolism ◽  
Fatty Acid Status ◽  
Δ5 Desaturase ◽  
Acid Status ◽  
Δ6 Desaturase

The fetus requires an adequate supply of fatty acids for optimum growth and development. It has been hypothesized that reduced activity of enzymes of fatty acid metabolism could contribute to inadequate fetal growth. In a porcine model of differential fetal growth we examined heart and liver fatty acid synthase, Δ5-desaturase and Δ6-desaturase gene expression and measured hepatic fatty acid profile to assess long-chain polyunsaturated fatty acid status. On gestation days 45, 65 and 100 sows were killed and tissues extracted from an average-sized fetus and the smallest fetus from each litter. As early as day 45, considerable hepatic Δ5- and Δ6-desaturase was detected, and this expression significantly increased as gestation progressed. In contrast, cardiac desaturase expression remained stable with time. Fatty acid synthase expression was greatest at day 65 in the liver, but was not expressed in the heart. Overall, the smallest fetus did not exhibit reduced tissue Δ5- or Δ6-desaturase expression or compromised polyunsaturated fatty acid status at any stage. In fact, small fetuses expressed more cardiac Δ5-desaturase than their average-sized siblings, possibly in response to a stress to the heart. It is clear from this study that fatty acid metabolism changes markedly as gestation progresses, and reduced fatty acid supply does not cause inadequate growth in this porcine model of fetal development.

scholarly journals Olive Oil Effects on Colorectal Cancer

Nutrients ◽  
2018 ◽  
Vol 11 (1) ◽  
pp. 32 ◽  
Author(s):  
Antonio Borzì ◽  
Antonio Biondi ◽  
Francesco Basile ◽  
Salvatore Luca ◽  
Enzo Vicari ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Gut Microbiota ◽  
Olive Oil ◽  
Mediterranean Diet ◽  
Protective Action ◽  
Chemotherapeutic Agents ◽  
Oil Consumption ◽  
Active Metabolites ◽  
Microbial Composition ◽  
Beneficial Effects

Colorectal cancer is the fourth cause of cancer-related death worldwide. A Mediterranean diet showed protective action against colorectal cancer due to the intake of different substances. Olive oil is a fundamental component of the Mediterranean diet. Olive oil is rich in high-value health compounds (such as monounsaturated free fatty acids, squalene, phytosterols, and phenols). Phenolic compounds exert favourable effects on free radicals, inflammation, gut microbiota, and carcinogenesis. The interaction between gut microbiota and olive oil consumption could modulate colonic microbial composition or activity, with a possible role in cancer prevention. Gut microbiota is able to degrade some substances found in olive oil, producing active metabolites with chemopreventive action. Further clinical research is needed to clarify the beneficial effects of olive oil and its components. A better knowledge of the compounds found in olive oil could lead to the development of nutritional supplements or chemotherapeutic agents with a potential in the prevention and treatment of colorectal cancer.

scholarly journals The role of fatty acid desaturase (FADS) genes in oleic acid metabolism: FADS1 Δ7 desaturates 11-20:1 to 7,11-20:2

2018 ◽  
Vol 128 ◽  
pp. 21-25 ◽  
Author(s):  
Hui Gyu Park ◽  
Matthew G. Engel ◽  
Kyle Vogt-Lowell ◽  
Peter Lawrence ◽  
Kumar S. Kothapalli ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Fatty Acid ◽  
Acid Metabolism ◽  
Fatty Acid Desaturase

scholarly journals 13C nuclear magnetic resonance spectroscopy to check 1,3-random, 2-random pattern of fatty acid distribution in olive oil triacylglycerols

2005 ◽  
Vol 19 (2) ◽  
pp. 109-117 ◽  
Author(s):  
Giovanna Vlahov
Keyword(s):  
Oleic Acid ◽  
Fatty Acid ◽  
Olive Oil ◽  
Random Distribution ◽  
Fatty Acid Distribution ◽  
Computer Method ◽  
Random Pattern ◽  
13C Nuclear Magnetic Resonance ◽  
Oleic And Linoleic Acids ◽  
C Nmr

The fatty acid distribution between the 1,3- and 2-positions of triglycerides was determined in the olive oil set sampled in the Marche region, by using the13C NMR method which applies the DEPT pulse sequence. The results confirmed that the oleic and linoleic acids were not randomly distributed at the 2-position of triacylglycerols but were lower for oleic acid and higher for linoleic acid compared to the theoretical values expected for a random distribution. Moreover, the unsaturated acids deviated from the 2-random distribution at different extents according to the acid concentration of triglyceride.The13C NMR results, they were obtained for three olive oil samples characterized by high, medium and low oleic acid at 2-position (Ofound) corresponding to a low, medium, high deviation rate from the 2-random pattern, were compared to those calculated by the computer program based on the 1,3-random-2-random distribution of fatty acids in the triglycerides.The molar concentrations of the triglyceride species LLL and OLL were calculated from the molar concentrations of oleic and linoleic acids at the 2- and 1,3-positions obtained by using13C NMR and the computer method. The LLL and OLL triglycerides determined by the computer method were found to be markedly higher in the “high Ofound” oil as compared to NMR. No differences were detected between the two methods for both triglyceride species in the “low Ofound” oil.

Characterization of the Olive Oil from Three Potentially Interesting Varieties from Aragon (Spain)

2010 ◽  
Vol 16 (6) ◽  
pp. 523-530 ◽  
Author(s):  
M. Benito ◽  
R. Oria ◽  
A.C. Sánchez-Gimeno
Keyword(s):  
Oleic Acid ◽  
Fatty Acid ◽  
Olive Oil ◽  
Gallic Acid ◽  
Sensory Analysis ◽  
Tocopherol Content ◽  
Oil Yield ◽  
Oleic Acid Content ◽  
Olive Oils ◽  
Very High

The commercial potential of olive oils from three autochthonous olive varieties Bodocal, Racimilla and Negral from Aragón (Spain) has been examined. Physicochemical characteristics, sensory analysis, nutritional composition, color and pigments were considered. The three varieties are generally used for producing table olives or olive oil in coupages but not for the production of monovarietal virgin olive oil. The values of the physicochemical and sensory analysis for the three olive oils corresponded to extra virgin category, however important differences among the three oils were observed in relation to pigment content, color measurements and fatty acid and phenol and tocopherol composition. Several characteristics such as oil yield, fatty acid and phenol and tocopherol content and sensory profiles suggested that some of these oils are of a promising composition. The olive yield of the Bodocal variety was the lowest (17%) and its corresponding oil had the smallest oleic acid (69%), phenols (272 mg gallic acid/kg) and tocopherol (96 mg/kg) contents and not equilibrated sensory parameters. The main characteristics of the Racimilla variety were a very high oil yield (28%) with very high contents in oleic acid (79 %) and phenols (831 mg gallic acid/kg). The oil of the Negral variety had very equilibrated sensory properties and its oleic acid content (76%) was similar to that of Racimilla. Its phenol content (456 mg gallic acid/kg) was between that of the other two varieties and its tocopherol content (190 mg/kg) was the highest. Therefore, the two last varieties could be of great interest for producing monovarietal olive oils.

scholarly journals Phenolic compounds and fatty acids content of some West Algerian olive oils

2020 ◽  
Vol 11 ◽  
pp. e3247
Author(s):  
Mounsif Charaf-eddine BENDI DJELLOUL ◽  
Sidi Mohamed Amrani ◽  
Pierangela Rovellini ◽  
Roza Chenoune
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Oleic Acid ◽  
Fatty Acid ◽  
Phenolic Compounds ◽  
Olive Oil ◽  
Acid Composition ◽  
High Performance ◽  
Primary Source ◽  
Olive Oils

Olive represents the most widespread fruit cultivated in Algeria. Olive oil is the primary source of added fat in the Mediterranean diet with health benefits of which have been verified for millennia. Interest in phenolic compounds in olive oil has increased due to its antioxidant activity, which plays a very important role in human health. The present study is carried out to study the phenolic compounds and fatty acids profile of some olive oils from western Algeria. The quality parameters (acidity, peroxide value, K232, K270), tocopherol analysis, fatty acid composition and phenolic profile were determined by High performance chromatography (HPLC). The results showed that chemlal oil (SBA) recorded the highest level of tocopherol-α with 228.12 mg/Kg. Regarding the fatty acid composition, oleic acid was the most dominant, oil Oleaster (Bensekrane) records the highest percentage (72.80%) of oleic acid. The quantitative data on the phenolic content of the seven samples revealed that chemlal oil (SBA) had the highest level of polyphenols (328.99 mg/Kg). However, Sigoise oil (Sebra1) was characterized by the highest levels of tyrosol and hydroxytyrosol (15.89 mg/kg and 22.42 mg/kg, respectively). The highest concentrations of oleuropein derivatives and ligstroside derivatives were observed in chemlal oil (SBA) and the recoreded values were 105.97 mg/Kg and 83.49 mg/Kg, respectively. Chemlal oil (SBA) was characterized by the highest amount of lignans (35.93 mg/Kg), luteolin (10.16 mg/Kg) and apigenin (5.44 mg/Kg). Oleocanthal was found in all the tested samples and it was higher in Chemlal oil (102.43 mg/kg).

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