Volatile oil profile of some lamiaceous plants growing in Saudi Arabia and their biological activities
AbstractA comparative investigation of hydro-distilled essential oils from aerial parts ofMentha longifoliaL. (ML),Mentha microphyllaK.Koch (MM),Mentha australisR.Br. (MA), andTeucrium poliumL. (TP) growing in Al Madinah Al Munawwarah, Saudi Arabia, was carried out. The total numbers of identified constituents were 22, 23, 14, and 20 in ML, MM, MA, and TP oils, representing 93.0, 99.3, 78.1, and 81.1% of the total oil composition, respectively. Pulegone (40.7%) and cineole (33.4%) were the major components in ML, whereas carvone (64.6%) was the major one in MM. Furthermore, β-linalool (22.9%) and α-terpineol (12%) were the major components in MA, whereas, (E)-3-caren-2-ol accounted for 12.1% in TP. The essential oils of TP and MA exhibited promising activities againstLeishmania donovanipromastigotes with IC50values of 2.3 and 3.7 μg/mL, respectively. In contrast, MA essential oils exhibited antifungal activities towardsCandida kruseiandC. glabratawith IC50values of 1 and 1.2 μg/mL, respectively.